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Institute For Basic Science patents


Recent patent applications related to Institute For Basic Science. Institute For Basic Science is listed as an Agent/Assignee. Note: Institute For Basic Science may have other listings under different names/spellings. We're not affiliated with Institute For Basic Science, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "I" | Institute For Basic Science-related inventors


Quantum dot electronic device and quantum dot transfer printing method

A quantum dot electronic device comprises a first encapsulation layer, a first electrode disposed on the first encapsulation layer, a quantum dot pattern disposed on the first electrode, a second electrode disposed on the quantum dot pattern and a second encapsulation layer disposed on the second electrode. The quantum dot pattern may be famed by an intaglio transfer printing method, where the method comprises forming a quantum dot layer on a donor substrate, picking up the quantum dot layer using a stamp, putting the quantum dot layer into contact with an intaglio substrate using the stamp and separating the stamp from the intaglio substrate. ... Institute For Basic Science

Method for analyzing 3' end sequence of messenger rna

The present disclosure provides a new protocol for sequencing the 3′ end of messenger rna (mrna). The present disclosure can be very favorably used in analyzing the repetitive sequences of nucleic acids, which are difficult to analyze by current sequencing methods, especially, homopolymeric sequences (poly[a] sequence) of mrna. ... Institute For Basic Science

Endonuclease targeting blood coagulation factor viii gene and composition for treating hemophilia comprising same

The present invention provides a method for inducing an inversion of normal blood coagulation factor viii (f8) gene, a method for correcting an inversion of blood coagulation factor viii gene in which the inversion has occurred, and a hemophilia a patient-derived induced pluripotent stem cell in which the inversion is corrected, constructed using the same. The method of the present invention effectively reproduces the inversion of intron 1 and intron 22 of the f8 gene, which is responsible for the majority of severe hemophilia a, and thereby may be effectively used for studying the development mechanism of hemophilia a and as a research tool for screening therapeutic agents. ... Institute For Basic Science

Endonuclease targeting blood coagulation factor viii gene and composition for treating hemophilia comprising same

The present invention provides a method for inducing an inversion of normal blood coagulation factor viii (f8) gene, a method for correcting an inversion of blood coagulation factor viii gene in which the inversion has occurred, and a hemophilia a patient-derived induced pluripotent stem cell in which the inversion is corrected, constructed using the same. The method of the present invention effectively reproduces the inversion of intron 1 and intron 22 of the f8 gene, which is responsible for the majority of severe hemophilia a, and thereby may be effectively used for studying the development mechanism of hemophilia a and as a research tool for screening therapeutic agents. ... Institute For Basic Science

Endonuclease targeting blood coagulation factor viii gene and composition for treating hemophilia comprising same

The present invention provides a method for inducing an inversion of normal blood coagulation factor viii (f8) gene, a method for correcting an inversion of blood coagulation factor viii gene in which the inversion has occurred, and a hemophilia a patient-derived induced pluripotent stem cell in which the inversion is corrected, constructed using the same. The method of the present invention effectively reproduces the inversion of intron 1 and intron 22 of the f8 gene, which is responsible for the majority of severe hemophilia a, and thereby may be effectively used for studying the development mechanism of hemophilia a and as a research tool for screening therapeutic agents. ... Institute For Basic Science

Genome editing with split cas9 expressed from two vectors

The present invention relates to a method for regulating gene expression, comprising introducing into a cell each of a recombinant vector which expresses a first domain comprising n-terminus of a cas9 protein, and a recombinant vector which expresses a second domain comprising c-terminus of a cas9 protein, a composition comprising the recombinant vectors, a kit for regulating gene expression, and a method for intracellular production of cas9 protein. Moreover, the present invention relates to a transformed cell introduced with a viral vector which packages the first domain, and a viral vector which packages the second domain, and to a composition comprising a virus produced therefrom.. ... Institute For Basic Science

Immune-compatible cells created by nuclease-mediated editing of genes encoding hla

The present invention relates to a method for producing immune-compatible cells or a cell population which comprises a step of editing one or two alleles of one or more immune-compatible antigen genes by gene deletion or modification in an isolated cell comprising at least one of the immune-compatible antigen genes selected from hla (human leukocyte antigen)-a, hla-b and hla-dr, to immune-compatible cells produced by the method, and to a cell population comprising the immune-compatible cells produced by the method. . ... Institute For Basic Science

Cell sheet manufacturing device and manufacturing method therefor

The present invention relates to a cell sheet manufacturing device and a manufacturing method therefor. More specifically, the present invention relates to a cell sheet manufacturing device comprising a support layer made of silicon rubber, a patterned electrode formed adjacent to the support layer and a graphene layer formed adjacent to the electrode, and a manufacturing method therefor.. ... Institute For Basic Science

Quantum dot electronic device and quantum dot transfer printing method

A quantum dot electronic device comprises a first encapsulation layer, a first electrode disposed on the first encapsulation layer, a quantum dot pattern disposed on the first electrode, a second electrode disposed on the quantum dot pattern and a second encapsulation layer disposed on the second electrode. The quantum dot pattern may be formed by an intaglio transfer printing method, where the method comprises forming a quantum dot layer on a donor substrate, picking up the quantum dot layer using a stamp, putting the quantum dot layer into contact with an intaglio substrate using the stamp and separating the stamp from the intaglio substrate. ... Institute For Basic Science

Method for sensitive detection of target dna using target-specific nuclease

The present invention relates to a method for analyzing a genotype using a target-specific nuclease and, specifically, to a method for diagnosing cancer or analyzing a genotype by removing wild type dna or particular genotype dna using a target-specific nuclease or a variant thereof to amplify or concentrate only a small amount of dna which has a difference in variation, such as a mutation, or genotype, and to a method for separating target dna sesusing a target-specific nuclease or a variant thereof. Such methods are novel paradigm methods contrary to existing simple target-specific nucleases for post-pcr recognition of normal genotype and carcinogenic genotype, and can be favorably used in the early diagnosis of cancer or analysis of similar genotypes.. ... Institute For Basic Science

System for measuring displacement of accelerating tube in high-vacuum chamber by using micro-alignment telescope and method thereof

A system for measuring displacement of an accelerating tube by using a micro-alignment telescope, which includes a vacuum chamber; a hollow accelerating tube in the vacuum chamber; a sighting target attached to a surface of the accelerating tube while protruding from the surface of the accelerating tube; the micro-alignment telescope spaced apart from one side surface of the vacuum chamber; a first lens device interposed between the micro-alignment telescope and the vacuum chamber; and a second lens device spaced apart from an opposite side surface of the vacuum chamber by a distance, wherein the vacuum chamber includes first and second viewports placed on the surfaces of the vacuum chamber in correspondence with each other, and the micro-alignment telescope, the first lens device, the first viewport, the sighting target, the second viewport and the second lens device are aligned on a same axis in one direction.. . ... Institute For Basic Science

A method of selecting a nuclease target sequence for gene knockout based on microhomology

The present invention relates to a method of selecting a nuclease target sequence for gene knockout based on microhomology.. . ... Institute For Basic Science

Novel chiral metal complex and use thereof for analyzing chirality of charged compound by 1h nmr spectroscopy

Provided are novel ligand, a chiral metal complex including the same, and a use of the chiral metal complex for analyzing the chirality of a charged compound by 1h nmr spectroscopy. The chiral metal complex of the present invention may be used as the chiral solvating agent to conveniently analyze the optical purity of charged compounds such as various amine derivatives, carboxylic acid derivatives, cyanohydrin derivatives and charged metal complexes by 1h nmr spectroscopy.. ... Institute For Basic Science








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