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Intelgenx Corp patents


Recent patent applications related to Intelgenx Corp. Intelgenx Corp is listed as an Agent/Assignee. Note: Intelgenx Corp may have other listings under different names/spellings. We're not affiliated with Intelgenx Corp, we're just tracking patents.

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Solid oral film dosage forms and methods for making same

Improved pharmaceutical solid oral dosage forms for the buccal and/or sublingual delivery of tadalafil. The improved delivery systems for solubilizing and stabilizing pharmaceutically active ingredients exhibit enhanced methods of preparation by the use improved solubilization systems which can maintain the tadalafil in a buccal and/or sublingual oral dosage form or a polymeric film matrix that provides improved bioavailability and/or absorption of tadalafil.. ... Intelgenx Corp

Montelukast transmucosal film

An oral film product in which a pharmaceutically active agent is stabilized in its partially-ionized form to better facilitate oral transmucosal delivery is provided. The film includes a bioadhesive layer including a pharmaceutically active agent having a logarithmic acid dissociation constant that is less than 4.5 and which is complexed with a cationic polymer.. ... Intelgenx Corp

Film dosage form with extended release mucoadhesive particles

An orally administered dosage form that facilitates delivery of an agent locally in the buccal cavity for a sustained period of time includes mucoadhesive particles that are made of at least a mucoadhesive material combined with the agent, and which are dispersed in a disintegrating film. The dosage form is capable of delivering an agent to a patient at the desired oral mucosa site over an extended period of time while reducing patient discomfort or annoyance associated with conventional sustained release mucoadhesive films that must reside on the oral mucosa during the period of sustained release.. ... Intelgenx Corp

Loxapine film oral dosage form

A loxapine film oral dosage form includes loxapine salt, free base, or prodrug in an amount effective to provide relief from acute agitation associated with schizophrenia or bipolar 1 disorder via oral transmucosal delivery, dispersed in a polymeric film forming system. Advantageously, the film oral dosage form further includes a sweetener, a refreshing agent, an antioxidant, a ph stabilizer, a penetration enhancer, a mucoadhesive agent and a plasticizer. ... Intelgenx Corp

Solid oral film dosage forms and methods for making same

Oral film dosage forms that provide improved solubilization and stabilization of an active ingredient in particle form include at least one primary crystallization inhibitor in an amount that inhibits growth and/or agglomeration of the active ingredient, a polyoxyethylated fatty acid glycerides in an amount that further enhances inhibition of crystallization, growth and agglomeration of the particles of the pharmaceutically active ingredient; and at least one plasticizer present in an amount that is effective to increase flexibility and elasticity of the film dosage form.. . ... Intelgenx Corp








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