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Karyopharm Therapeutics Inc patents


Recent patent applications related to Karyopharm Therapeutics Inc. Karyopharm Therapeutics Inc is listed as an Agent/Assignee. Note: Karyopharm Therapeutics Inc may have other listings under different names/spellings. We're not affiliated with Karyopharm Therapeutics Inc, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "K" | Karyopharm Therapeutics Inc-related inventors


Polymorphs of selinexor

The present invention relates to crystalline forms of the compound represented by structural formula i, and compositions comprising crystalline forms of the compound represented by structural formula i described herein. The crystalline forms of the compound of structural formula i and compositions comprising the crystalline forms of the compound of structural formula i provided herein, in particular, single crystalline form a, can be incorporated into pharmaceutical compositions, which can be used to treat various disorders associated with crm1 activity, including cancer. ... Karyopharm Therapeutics Inc

Cyclic compounds and uses thereof

. . . . The invention generally relates to substituted benzothiophenyl, substituted benzothiazolyl, substituted indolyl and substituted benzoimidazolyl compounds and, more particularly, to a compound represented by structural formula i: or a pharmaceutically acceptable salt thereof, wherein the variables are as defined and described herein. The invention also includes the synthesis and use of a compound of structural formula i, or a pharmaceutically acceptable salt or composition thereof, e.g., in the treatment of a disease or disorder selected from cancer (e.g., lymphoma, such as mantle cell lymphoma), a neurodegenerative disease, inflammatory diseases or an autoimmune system disease (e.g., a t-cell mediated autoimmune disesase).. ... Karyopharm Therapeutics Inc

Multicyclic compounds and methods of using same

. . . . The invention generally relates to compounds represented by structural formula i: or a pharmaceutically acceptable salt thereof, wherein the variables are as defined and described herein. The invention also includes the synthesis and use of a compound of structural formula i, or a pharmaceutically acceptable salt or composition thereof, e.g., in treatment of cancer (e.g., mantle cell lymphoma), and other diseases and disorders (e.g., pak-mediated, for example, pak4-mediated, diseases and disorders).. ... Karyopharm Therapeutics Inc








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