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Kyoto University patents


Recent patent applications related to Kyoto University. Kyoto University is listed as an Agent/Assignee. Note: Kyoto University may have other listings under different names/spellings. We're not affiliated with Kyoto University, we're just tracking patents.

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Separation method for halogenated unsaturated carbon compound

The method according to this disclosure is a method for separating an unsaturated hydrocarbon having 2 or 3 carbon atoms and a halogenated unsaturated carbon compound formed by replacing at least one of hydrogen atoms included in the unsaturated hydrocarbon with a fluorine atom, from each other and is a method for selectively adsorbing either the unsaturated hydrocarbon or the halogenated unsaturated carbon compound by a porous coordination polymer that includes a metallic ion having a valence of 2 to 4 and an aromatic anion having 1 to 6 aromatic ring(s).. . ... Kyoto University

Lifesaving assisting apparatus

. . A light-emitting section (21) emits light to be irradiated on a body of a patient (100). A light-receiving section (22) outputs a signal corresponding to an intensity of light which has been transmitted through or reflected from the body of the patient (100). ... Kyoto University

Composite membrane and method of fabricating the same

Disclosed is a composite membrane including a polymeric membrane having an h2 permeability of 500 barrer or more at 25 degrees c., and a coating layer deposited on the polymer membrane by oxidative polymerization.. . ... Kyoto University

Method for screening induced pluripotent stem cells

The present invention provides a method for screening for ips cells exhibiting differentiation resistance using a marker identified as lincrna or mrna that is specifically expressed in an ips cell line exhibiting differentiation resistance, and such markers.. . ... Kyoto University

Metal oxide film formation method

Disclosed herein in a method of forming a metal oxide film, which can provide a high-quality metal oxide film while enhancing production efficiency. The method includes the steps of: turning a raw-material solution having a metallic element into a mist, to obtain a raw-material solution mist; turning a reaction aiding solution into a mist, to obtain an aiding-agent mist; feeding the raw-material solution mist and the aiding-agent mist into a mixing vessel, thereby mixing the raw-material solution mist and the aiding-agent mist, to obtain a mixed mist; and feeding the mixed mist onto a back surface of a substrate which is heated, to obtain a metal oxide film.. ... Kyoto University

Method for inducing differentiation of pluripotent stem cells into germ cells

The invention provides a method for inducing human primordial germ cell-like (pgc-like) cells from human pluripotent stem cells, with high efficiency and high reproducibility, and a cell surface marker for identifying human pgc-like cells. In particular, the invention provides a method for producing a human pgc-like cell from a human pluripotent stem cell, includes a step of producing a mesoderm-like cell by culturing a human pluripotent stem cell in a culture medium comprising activin a and a gsk3β inhibitor, and a step of culturing the mesoderm-like cell in a culture medium containing bmp. ... Kyoto University

Therapeutic agent associated with suppression of proliferation and metastasis of tumor, which comprises exosomes released from cytotoxic t cells and targets cancer stromal/mesenchymal cells

Therapeutic agents effective for treating cell-proliferative diseases contain extracellular vesicles (exosomes) released from cytotoxic t cells or mirna obtained from extracellular vesicles (exosomes) released from cytotoxic t cells, such as human cd8+ t cells. Such therapeutic agents suppress the proliferation of mesenchymal cells surrounding cancer cells, e.g., by killing the mesenchymal cells, such that the cancer cells become isolated and unable to metastasize. ... Kyoto University

Novel triglyceride and use thereof

The invention provides a hya derivative having superior physiological functions intrinsic to hya and permitting easy ingestion and easy handling, and use thereof. In particular, the invention relates to a triglyceride in which at least one fatty acid forming an ester bond with a hydroxy group of glycerol is 10-hydroxy-cis-12-octadecenoic acid, or an optical isomer thereof, and a composition (edible fat or oil, food, medicament, cosmetic etc.) containing same.. ... Kyoto University

Separating medium and column for liquid chromatography

The present invention provides a separating medium including porous resin particles which has a sufficient pore diameter suitable for liquid chromatography applications and which has high strength, is reduced in pressure loss during liquid passing, has the excellent property of separating a desired substance, and has low nonspecific adsorption properties. The separating medium of the invention is a separating medium obtained by treating porous epoxy resin particles and having an average pore diameter of 10 to 2,000 nm, or a separating medium obtained by treating porous epoxy resin particles and having a water content of 50% or higher.. ... Kyoto University

Acetylene removal from light hydrocarbon mixtures by metal-organic framework exhibiting dual size and chemical selectivities

The present invention provides a gas separation system and a gas separation method capable of separating various types of hydrocarbon gas with high selectivity, and a gas separation system is for separating one type or more of hydrocarbon gases from mixed gas consisting of two types or more of hydrocarbon gases; having a porous metal-organic complex having pores determined by metal ion-containing planar ligands facing each other and pillar ligands coordinating between the planar ligands, and a controller for controlling at least a pressure of the mixed gas; and in which the pressure is controlled to control adsorption of the hydrocarbon gas to the porous metal-organic complex or desorption thereof from the porous metal-organic complex.. . ... Kyoto University

Liquid injection method

A liquid injection method for injecting a liquid into a culture vessel includes tilting the culture vessel around a horizontal axis at a tilt angle (x°) of greater than 0° and 50° or less, wherein adherent cells are adhered to the culture vessel; and injecting the liquid into the culture vessel at a predetermined linear velocity (y mm/s) via a wall surface of the culture vessel tilted at the tilt angle (x°), wherein the tilt angle (x) and the linear velocity (y) satisfy the following (formula 1): y≤5.075x+123 (formula 1).. . ... Kyoto University

Method for producing myocardial cells using synthetic peptide

Provided is a method for producing myocardial cells from pluripotent stem cells. The myocardial cell production method provided by the present invention includes supplying an artificially produced synthetic peptide to a cell culture that contains pluripotent stem cells. ... Kyoto University

Hepatocyte induction method

. . A method for producing hepatocytes from hepatoblasts is provided. The method includes the step of culturing the hepatoblasts in a medium containing a compound selected from the group consisting of pregnenolone and an adrenergic agonist. ... Kyoto University

Method for sorting tissue cells

An object of the present invention is to provide a method for increasing the purity of a type of tissue cell such as an endothelial cell, a hepatocyte, or an insulin-producing cell. The present invention solves the problem by providing a method comprising a step of introducing, into a cell population, an mrna comprising a nucleic acid sequence recognized by an mirna specifically expressed in endothelial cells, hepatocytes, or insulin-producing cells.. ... Kyoto University

02/22/18 / #20180051256

Method for inducing differentiation of alveolar epithelial cells

. . This invention provides a method for stably producing type ii alveolar epithelial cells from pluripotent stem cells. Specifically, the invention relates to a method for producing type ii alveolar epithelial cells from pluripotent stem cells comprising steps of: (1) culturing pluripotent stem cells in a medium containing activin a and a gsk3β inhibitor; (2) culturing the cells obtained in step (1) in a medium containing a bmp inhibitor and a tgfβ inhibitor; (3) culturing the cells obtained in step (2) in a medium containing bmp4, retinoic acid, and a gsk3β inhibitor; (4) culturing the ventral anterior foregut cells obtained in step (3) in a medium containing a gsk3β inhibitor, fgf10, kgf, and a notch signal inhibitor; and (5) subjecting the alveolar epithelial progenitor cells obtained in step (4) to three-dimensional culture in a medium containing a steroid drug, a camp derivative, a phosphodiesterase inhibitor, and kgf.. ... Kyoto University

02/15/18 / #20180047913

Material for organic electroluminescent elements, organic electroluminescent element, display device, and lighting device

Provided is an organic electroluminescent element which has improved driving voltage and improved current efficiency. An organic electroluminescent element having the above-mentioned improved characteristics is provided by using, as a material for organic electroluminescent elements, a polycyclic aromatic compound in which a nitrogen atom and another heteroatom or a metal atom (x) are adjacent to each other in a non-aromatic ring.. ... Kyoto University

02/15/18 / #20180044714

Nucleic acid sequence amplification method

The invention provides a method of preparing a nucleic acid population suitable for rna sequencing. The method involves amplifying a double-stranded dna and a poly t sequence by using the dna constituted of any additional nucleic acid sequence x, poly t sequence, mrna sequence isolated from a biological sample, poly a sequence and any additional nucleic acid sequence y in this order as a template, a first primer containing any additional nucleic acid sequence x having amine added to the 5′-terminal (and a poly t sequence), and a second primer containing any additional nucleic acid sequence y (and a poly t sequence), followed by fractionalizing the dna, phosphorylating the dna, preparing cdna by using the dna as a template and a third primer, adding adenine (a) to the cdna, linking a dna, and amplifying the dna by using the dna as a template, a fourth primer, and a fifth primer.. ... Kyoto University

02/15/18 / #20180044634

Method for producing culture containing megakaryocytes, and method for producing platelets using same

The present invention provides a method for producing megakaryocytes that have an increased capacity to produce platelets, the method comprising a step of culturing, under conditions that cause the death of cells that do not express a gene that is specifically expressed by megakaryocytes, cells that have the capacity to differentiate into megakaryocytes.. . ... Kyoto University

01/25/18 / #20180022655

Method for manufacturing ceramic material, capacitor, solid oxide fuel cell, water electrolysis device, and hydrogen pump

A method for manufacturing a ceramic material includes a step of performing heat treatment in a reducing atmosphere on a ceramic material in which a metallic oxide is diffused in crystal grains, thereby to reduce the metallic oxide to deposit a metallic element at grain boundaries of the ceramic material.. . ... Kyoto University

01/18/18 / #20180015171

High-density lipoprotein, and delivery of drug to posterior segment of eye by ocular instillation of said cytophilic peptide-fused high-density lipoprotein

The purpose of the present invention is to provide a novel system for the delivery of a drug to a posterior segment of the eye. The present invention relates to: a cytophilic peptide-fused high-density lipoprotein (chdl) which can be used as a carrier for the delivery of a drug to a posterior segment of the eye; a method for producing the cytophilic peptide-fused high-density lipoprotein; a system of the delivery of a drug to a posterior segment of the eye, a pharmaceutical composition, and a system of the delivery of a drug to a posterior segment of the eye, each of which utilizes the cytophilic peptide-fused high-density lipoprotein; and a method for diagnosing, preventing or treating posterior ocular disease.. ... Kyoto University

01/04/18 / #20180005277

User interest estimation system and information delivery system

. . The purpose of the present invention is to provide a user interest estimation system and an information delivery system capable of accurately estimating user's interest and eventually capable of delivering specific information such as advertisements while corresponding to the user. After having received photographic data related to a commodity or service transmitted via a network from a user's information terminal device 1, geographical or spatial context information related to a time and location included in the photographic data is acquired by referring to a context information database, object information pertaining to the commodity or service related to the time and location included in photographic data is obtained by referring to an object information database, and a user interest information is generated by associating the context information and the object information with each other.. ... Kyoto University

01/04/18 / #20180000771

Agent for preventing and/or treating amyotrophic lateral sclerosis

The present invention provides a prophylactic and/or therapeutic agent for amyotrophic lateral sclerosis (als), which contains one or more kinase inhibitors selected from the group consisting of an epithelial cell growth factor receptor (egfr) inhibitor, a fibroblast growth factor receptor (fgfr) inhibitor, an aurorakinase inhibitor, a protein kinase a (pka) inhibitor, a protein kinase c (pkc) inhibitor, an mek inhibitor, an met inhibitor, a jnk inhibitor, a syk inhibitor and a jak inhibitor, a prostaglandin analogue and an estrogen receptor antagonist, or one or more kinase inhibitors selected from the group consisting of tivozanib and an analog thereof, sb 216763, cdk2 inhibitor ii, budesonide, riboflavin, alpha-tochopherol, amodiaquine, su9516, sunitinib and an analog thereof, gsk-3 inhibitor xiii, bisindolylmaleimide i, hydroquinone, flunisolide, mgcd-265, indirubin-3′-monoxime, hydrastine (1r,9s), piperine, butamben, axitinib and an analog thereof, apomorphine, fenbufen, bosutinib (ski-606) and an analog thereof, a wee1 inhibitor, cdk2 inhibitor iv, nu6140, 3-hydroxybutyric acid, at9283, imatinib, nilotinib, rebastinib, and bafetinib for the prophylaxis and/or treatment of als. Particularly, using a compound already on the market as a pharmaceutical product, a pharmaceutical product for the prophylaxis or treatment of als can be developed rapidly at a low cost.. ... Kyoto University

12/28/17 / #20170370821

Method for selecting skeletal muscle progenitor cell

. . The present invention aims to provide a method of sorting a skeletal muscle progenitor cell from a cell population containing the skeletal muscle progenitor cell. The above-mentioned problem is solved by providing a step of introducing mirna-responsive mrna into a cell population. ... Kyoto University

12/21/17 / #20170363587

Structure evaluation system, structure evaluation apparatus, and structure evaluation method

According to an embodiment, a structure evaluation system includes a plurality of sensors, a position locator, and an evaluator. The sensors detect an elastic wave generated from a structure. ... Kyoto University

12/21/17 / #20170363586

Structure evaluation system, structure evaluation apparatus, and structure evaluation method

According to an embodiment, a structure evaluation system includes a plurality of ae sensors, a signal processor, a position locator, and an evaluator. The ae sensors detect an elastic wave generated from a structure. ... Kyoto University

12/21/17 / #20170362630

Observation method using binding and dissociation probe

An observation method of a sample containing a target substance, the observation method including an imaging step in which a step of obtaining a speckle image including, as a speckle, light emitted from a luminescent substance in which a medium is brought into contact with the sample is performed a plurality of times so as to obtain a plurality of speckle images, the medium containing a probe that contains the luminescent substance emitting light and that repeatedly binds to and dissociates from the target substance directly and specifically, and an observation image generation step of generating an observation image of the target substance in the sample from the plurality of speckle images, wherein a half-life of a probe-target complex formed by binding between the probe and the target substance is equal to or more than 10 milliseconds and equal to or less than 3 seconds.. . ... Kyoto University

12/21/17 / #20170362568

Endodermal cell production method, liver cell production method, pancreatic cell production method, endodermal cell induction promoter, liver cell induction promoting kit, pancreatic cell induction promoting kit, and microfluidic device

The present invention provides an endodermal cell production method that can induce differentiation of pluripotent cells into endodermal cells even when the pluripotent cells are dispersed and can achieve improved endodermal cell production efficiency. The endodermal cell production method according to the present invention is a method for producing endodermal cells by inducing differentiation of pluripotent cells into the endodermal cells, including the step of: inducing differentiation of the pluripotent cells into the endodermal cells in the presence of an endodermal cell inducing factor. ... Kyoto University

12/07/17 / #20170352921

Liquid electrolyte for fluoride ion battery and fluoride ion battery

An object of the present disclosure is to provide a liquid electrolyte for a fluoride ion battery in which decomposition of a solvent is restrained. The present disclosure attains the object by providing a liquid electrolyte for a fluoride ion battery comprising a plurality of carbonate-based solvents and a fluoride salt, wherein the plurality of carbonate-based solvents contain: i) only propylene carbonate (pc) and dimethyl carbonate (dmc), ii) only ethylene carbonate (ec) and ethyl methyl carbonate (emc), or iii) only ethyl methyl carbonate (emc) and dimethyl carbonate (dmc).. ... Kyoto University

12/07/17 / #20170352887

Anode layer for fluoride ion battery and fluoride ion battery

An object of the present disclosure is to provide an anode layer for a fluoride ion battery in which decomposition of a binder is restrained. The present disclosure attains the object by providing an anode layer to be used for a fluoride ion battery, the anode layer comprising an anode active material and a non-fluorine-based binder having aromaticity.. ... Kyoto University

12/07/17 / #20170352875

Secondary battery system

An object of the present disclosure is to provide a secondary battery system that functions at high voltage. The present disclosure attains the object by providing a secondary battery system comprising: a fluoride ion battery including a cathode active material layer, an anode active material layer, and an electrolyte layer formed between the cathode active material layer and the anode active material layer; and a controlling portion that controls charging and discharging of the fluoride ion battery; wherein the cathode active material layer contains a cathode active material with a crystal phase that has a perovskite layered structure and is represented by an+1bno3n+1-αfx (a comprises at least one of an alkali earth metal element and a rare earth element; b comprises at least one of mn, co, ti, cr, fe, cu, zn, v, ni, zr, nb, mo, ru, pd, w, re, bi, and sb; “n” is 1 or 2; “α” satisfies 0≦α≦3.5; and “x” satisfies 0≦x≦5.5); and the controlling portion controls charging so that a value of f/b in the cathode active material becomes more than 2/n that is in an over-charged state.. ... Kyoto University

12/07/17 / #20170351081

Observation system, observation program, and observation method

An observation system includes a microscope optical system, an image pickup unit, an image pickup control unit, a detection unit, and an observation control unit. The image pickup unit is configured to take an image of a field-of-view range of the microscope optical system. ... Kyoto University

12/07/17 / #20170349883

Mature cardiac muscle cell marker

From a cell population containing cardiomyocytes, the cardiomyocytes are extracted using a marker(s) specific to cardiomyocytes, that is, at least one marker selected from corin, ncam1, cryab, hbegf, dmd, atpif1, cav2, itgav, dcbld2, clic4, bmpr2, ctsb, tmem123, usp14, and mir761.. . ... Kyoto University

11/30/17 / #20170346316

Secondary battery system

. . An object of the present disclosure is to provide a secondary battery system that functions at high voltage. The present disclosure attains the object by providing a secondary battery system comprising: a hybrid ion battery provided with a cathode active material layer having a cathode active material that contains a metal element capable of taking two kinds or more of a positive valence, an anode active material layer having an anode active material that contains a metal element capable of taking a valence of +2 or more, and an electrolyte layer containing an alkali metal ion and fluoride anion, and formed between the cathode active material layer and the anode active material layer; and a controlling portion that controls charging and discharging of the hybrid ion battery; wherein the controlling portion controls discharging so that a potential of the cathode active material includes a potential range higher than 0.23 v (vs. ... Kyoto University

11/30/17 / #20170342439

Method for extracting differentiated cells

A method for extracting differentiated cells from a cell population comprising undifferentiated cells after induction of the differentiation of pluripotent stem cells. A method for extracting differentiated cells from a cell population, comprising the following steps: (1) a step of introducing, into a cell population, mrna comprising a marker gene operably linked to the target sequence of mirna specifically expressed in pluripotent stem cells; and (2) a step of extracting cells in which the marker gene has been translated.. ... Kyoto University

11/23/17 / #20170336365

Structure evaluation system, structure evaluation apparatus, and structure evaluation method

According to an embodiment, a structure evaluation system includes a plurality of sensors, a position locator, a velocity calculator, and an evaluator. The sensors detect an elastic wave generated from a structure. ... Kyoto University

11/23/17 / #20170336364

Structure evaluation system, structure evaluation apparatus, and structure evaluation method

According to an embodiment, a structure evaluation system includes a plurality of ae sensors, a signal processor, a position locator, a velocity calculator, and an evaluator. The ae sensors detect an elastic wave generated from a structure. ... Kyoto University

11/23/17 / #20170335285

Novel cardiomyocyte marker

The present invention provides a method for producing or detecting cardiomyocytes by extracting/detecting cardiomyocytes from a cell population which includes cardiomyocytes using, as an index, positivity of ncam1, ssea3, ssea4 and/or cd340.. . ... Kyoto University

11/16/17 / #20170327600

Rna-protein complex, and rna and protein delivery system using the same

An rna and protein delivery system utilizing an rna-protein complex having a higher-order structure, and an rna-protein complex having a novel higher-order structure.. . ... Kyoto University

11/16/17 / #20170326175

Method for induction of t cells from pluripotent stem cells

The present invention provides a method for efficiently inducing cd8-positive t cells by adding vitamin c to the medium in the steps of induction of the cd8-positive t cells from pluripotent stem cells. The present invention also provides a method for efficiently inducing cd8-positive t cells by performing culture in a medium supplemented with an adrenocortical hormone agent in the step of induction of the cd8-positive t cells from cd4/cd8 double-positive t cells.. ... Kyoto University

09/21/17 / #20170269204

Structure evaluation apparatus, structure evaluation system, and structure evaluation method

A structure evaluation apparatus has an acquisitor and an evaluator. The acquisitor acquires a distribution that represents a distribution of strength of a reflected wave obtained by an electromagnetic radar scan to a reinforced concrete which comprises concrete and a material other than concrete. ... Kyoto University

09/07/17 / #20170253934

Method for screening induced pluripotent stem cells

The present invention provides a method for screening for ips cells exhibiting differentiation resistance using a marker identified as lincrna or mrna that is specifically expressed in an ips cell line exhibiting differentiation resistance, and such markers.. . ... Kyoto University

09/07/17 / #20170252593

Test unit for simulating fires

The invention relates to a test unit for simulating fires, formed on the basis of an enclosure (1) in the form of a closed compartment with a floor, walls and ceiling made from reinforced concrete parts, which has an access area (2) located at one end of the enclosure (1), a central area (3) with side doors (4) and provided with an outflow passage (5) and one or more deflectors (6) for controlling the air and smoke, and a furnace area (7) covered in refractive material with a cleaning door (8) located at the opposite end of the enclosure (1). Said enclosure (1) incorporates temperature and smoke level probes (13), and all the electrical elements and probes (13) of the enclosure (1) are connected to a control panel (26) connected to a computer (28) that collects all the data supplied by such elements.. ... Kyoto University

09/07/17 / #20170251647

Method for knock-in of dna into target region of mammalian genome, and cell

This invention provides a method for knock-in of a donor dna into the genome of a cell, comprising introducing at least one artificial nuclease system capable of cleaving target sequence(s) of the cell genome, the donor dna, and two single-stranded oligonucleotides (ssodns) into the cell, the artificial nuclease system cleaving the target sequence(s) on the cell genome, the two ssodns each complementary to one of the ends generated by the target sequence cleavage in the cell genome and to one of the introduction ends of the donor dna, the donor dna being knocked-in at the cleavage site via the two ssodns.. . ... Kyoto University

08/17/17 / #20170237067

Active material and fluoride ion battery

The main object of the present invention is to provide an active material that has a favorable cycle property. The present invention achieves the object by providing an active material to be used for a fluoride ion battery comprising a crystal phase having a layered perovskite structure, and represented by an+1bno3n+1−αfx (a is composed of at least one of an alkaline earth metal element and a rare earth element; b is composed of at least one of mn, co, ti, cr, fe, cu, zn, v, ni, zr, nb, mo, ru, pd, w, re, bi, and sb; “n” is 1 or 2; “α” satisfies 0≦α≦2; and “x” satisfies 0≦x≦2.2).. ... Kyoto University

08/03/17 / #20170220704

Object display system for relationship graph

. . An object display system for a relationship graph includes an object information reception unit that receives object information from a terminal device. A node conversion unit converts the object information into a corresponding node and sets the node as a reference point node. ... Kyoto University

07/27/17 / #20170211070

Prophylactic agent and therapeutic agent for fibrodysplasia ossificans progressiva

The invention provides a prophylactic agent or therapeutic agent for fibrodysplasia ossificans progressiva, containing as an active ingredient a binding inhibitor that inhibits interaction between activin and activin a receptor type i (acvr1), or an expression suppressor that suppresses expression of activin.. . ... Kyoto University

07/13/17 / #20170198258

Culture medium for mesenchymal stem cells

Mesenchymal stem cells may be culture for a long period, without using any special apparatus, equipment and the like, in a medium in which seven kinds of nonessential amino acids of glycine, alanine, serine, proline, asparagine, aspartic acid, and glutamic acid are reduced.. . ... Kyoto University

06/22/17 / #20170175082

Method for producing pancreatic blast cells and pancreatic disease treatment agent containing pancreatic blast cells

Provided is a method for generating pancreatic bud cells, having the step of culturing pdx1+/nkx6.1− cells in a medium containing kgf, egf and a bmp inhibitor. The culturing step may be performed in suspension cultures or in adherent cultures. ... Kyoto University

06/22/17 / #20170175077

Culture medium composition and method of culturing cell or tissue using thereof

The present invention provides a culture method of cells and/or tissues including culturing cells and/or tissues in a suspended state by using a medium composition wherein indeterminate structures are formed in a liquid medium, the structures are uniformly dispersed in the solution and substantially retain the cells and/or tissues without substantially increasing the viscosity of the solution, thus affording an effect of preventing sedimentation thereof, and the like. . ... Kyoto University

06/01/17 / #20170152485

Method for inducing cardiac differentiation of pluripotent stem cell with low-molecular compounds

The present invention provides a method for inducing cardiac differentiation of a pluripotent stem cell, which comprises the steps of (1) culturing a pluripotent stem cell in a medium containing a wnt signaling activator and a pck activator and (2) culturing the cell after the step (1) in a medium containing a wnt signaling inhibitor, a src inhibitor, and an egfr inhibitor.. . ... Kyoto University

05/11/17 / #20170134449

Shared experience information construction system

In an information terminal processing device of a first user, after selection of a content on a prescribed experience by the first user, content identification information is output to an information terminal device of a second user b, and various information thereof is transmitted to a server device. In an information terminal device of a second user b, after the content identification information is input, a unique key corresponding to the content identification information is generated. ... Kyoto University

05/11/17 / #20170130202

Methods respectively for producing mesodermal cells and hematopoietic cells

The present invention aims to provide a novel method for producing mesodermal cells, and a graft material containing mesodermal cells obtained by this method. The present invention also aims to provide a novel method for producing hematopoietic cells, and a therapeutic agent for blood diseases containing a hematopoietic cell obtained by the method. ... Kyoto University

04/27/17 / #20170114322

Culture medium for pluripotent stem cells

An object of the present invention is to provide a medium that comprises fewer protein components and enables the maintenance of pluripotent stem cells in an undifferentiated state. The culture medium for pluripotent stem cells comprises a gsk3β inhibitor (a) and a dyrk inhibitor (b).. ... Kyoto University

04/20/17 / #20170108517

Mechanochemical platform and sensing methods using dna origami nanostructures

A biosensing platform capable of high throughput mechanochemical biosensing comprising a dna origami nanostructure having a plurality of slots into which recognition elements are strategically placed and apparatus that senses a change in the origami nanostructure in response to the introduction of a target where the apparatus includes a signal transduction unit and signal sensor which exploits mechanical signals in a recognition element which signal includes one or more mechanical tension or mechanochemical rearrangement event. The nanostructure is preferably a 2-dimensional or 3-dimensional arrangement of tiles linked by locking elements, such as aptamers that will open in response to an event such as exposure to a drug molecule, dna, rna or protein target.. ... Kyoto University

04/13/17 / #20170104237

Electrolytic solution for electrochemical devices and electrochemical device in which the electrolytic solution is used

An electrolytic: solution for electrochemical devices includes: a salt consisting of a bifluoride anion and a cation.; a compound containing boron; and an organic solvent.. . ... Kyoto University

03/16/17 / #20170077521

Anode current collector, conductive material, and fluoride ion battery

A main object of the present invention is to provide an anode current collector that is capable of inhibiting the reaction with liquid electrolyte. The present invention achieves the object by providing an anode current collector to be used for a fluoride ion battery; and the anode current collector being a simple substance of fe, mg, or ti, or an alloy containing one or more of these metal elements.. ... Kyoto University

03/09/17 / #20170067978

Image processing apparatus, magnetic resonance imaging apparatus, image processing method, and storage medium

Conventionally, it has been impossible to output an image that allows for an easy and accurate diagnosis as to whether or not a malignant tumor is present and that allows for correctly indicating a part with a high or low grade of malignancy in the tumor. With an image processing apparatus that includes: a receiving unit configured to receive diffusion weighted images; a parameter acquisition unit configured to acquire parameters of two or more types for each of one or more units of processing that constitute the diffusion weighted images, by using the diffusion weighted images; a diagnostic image composition unit configured to acquire, for each of the one or more units of processing, a score that corresponds to the parameters of two or more types, by using the parameters of two or more types, and to compose a diagnostic image that is an image having, for each of the one or more units of processing, a pixel value that corresponds to the acquired score that corresponds to the unit of processing; and an output unit configured to output the diagnostic image, it is possible to output an image that allows for an easy and accurate diagnosis as to whether or not a malignant tumor is present and that allows for correctly indicating a part with a high or low grade of malignancy in the tumor.. ... Kyoto University

03/02/17 / #20170062805

Fluoride ion battery

An object of the present invention is to provide a fluoride ion battery in which excess voltage at the time of charging is decreased. The present invention achieves the object by providing a fluoride ion battery comprising a cathode active material layer containing a cathode active material, an anode active material layer containing an anode active material, and an electrolyte layer formed between the cathode active material layer and the anode active material layer; wherein the anode active material is an alloy containing at least a ce element and a pb element.. ... Kyoto University

02/23/17 / #20170051292

Translational control system using rna-protein interaction motif

A translational control method using an rna-protein interaction motif is provided. The method comprises a step of introducing an mrna having: a 5′utr regulation structure comprising: (1) a cap structure at the 5′ terminus, (2) a spacer positioned on the 3′ side of the cap structure, and (3) one or more rna motifs positioned on the 3′ side of the spacer, which comprises an rna-protein interaction motif-derived nucleotide sequence or a variant thereof; and a nucleotide sequence encoding a target protein gene on the 3′ side of the 5′utr regulation structure, into a cell in the presence of a protein specifically binding to the rna motifs, wherein a translational level is decreased as the number of bases of the spacer decreases, and the translational level is decreased as the number of the rna motifs increases.. ... Kyoto University

02/02/17 / #20170033386

Proton conductor, method for producing proton conductor, and fuel cell

. . . . A proton conductor includes a coordination polymer having stoichiometrically metal ions, oxoanions, and proton coordinating molecules capable of undergoing protonation or deprotonation. The coordination polymer including coordination entities that are repeatedly coordinated to bond the coordination entities with one another. ... Kyoto University

02/02/17 / #20170033351

Alkaline storage battery

An alkaline storage battery contains: a positive electrode; a negative electrode containing, as an active material, at least one of a metal capable of forming a dendrite and a metal compound thereof; and an alkaline electrolyte. The alkaline electrolyte contains a compound which is a chain saturated hydrocarbon at least partially having a hydrophilic functional group other than a hydroxyl group and having a molecular weight of 400 or more and less than 220000 in an amount of less than 15 g per 100 ml of the electrolyte.. ... Kyoto University

02/02/17 / #20170033345

Storage battery

A storage battery includes a negative electrode including, as an active material, at least one of a metal capable of forming a dendrite and a metal compound thereof, a positive electrode, a separator, and an electrolyte containing an additive. In the storage battery, a concentration of the additive in the electrolyte in a region on a side of the negative electrode defined by the separator is higher than a concentration of the additive in a region on a side of the positive electrode.. ... Kyoto University

02/02/17 / #20170029927

Alloy for medical use, and method for producing same

The present invention provides an alloy for medical use including an au—pt alloy, in which the au—pt alloy has a pt concentration of 24 mass % or more and less than 34 mass % with the balance being au, and has at least a material structure in which a pt-rich phase having a pt concentration higher than that of an α-phase is distributed in an α-phase matrix, the pt-rich phase has a pt concentration that is 1.2 to 3.8 times the pt concentration of the α-phase, and the pt-rich phase has an area ratio of 1 to 22% in any cross-section. This alloy is an artifact-free alloy material that exhibits excellent compatibility with a magnetic field environment such as an mri and has magnetic susceptibility of ±4 ppm with respect to magnetic susceptibility of water.. ... Kyoto University

01/26/17 / #20170023548

Method of screening atp11c or cdc50a inhibitor

. . The present invention relates to a method for screening an inhibitor of atp11c or cdc50a, comprising determining (a) exposure of phosphatidylserine on cell surface, (b) engulfment of cells by macrophages, or (c) cleavage of atp11c by caspase. The present invention also relates to a method for inducing engulfment of cells by macrophages, comprising inhibiting atp11c or cdc50a.. ... Kyoto University

01/26/17 / #20170022223

Method for producing surface-modified base material, method for producing joined body, new hydrosilane compound, surface treatment agent, surface treatment agent kit, and surface-modified base material

The method for producing a surface-modified base material according to the present invention includes a step of bringing a base material having a polar group present on a surface thereof into contact with a hydrosilane compound having a molecular structure a and having a si—h group composed of a silicon atom of the molecular structure a and a hydrogen atom bonded to the silicon atom in the presence of a borane catalyst so as to allow a dehydrocondensation reaction to take place between the base material and the compound, thereby forming the base material surface-modified with the molecular structure a. This production method is capable of surface-modifying a base material at a lower temperature in a shorter time than conventional methods and allows a wide variety of options for the form, type, and application of the base material, the mode of the modification reaction, and the type of the molecular structure with which the base material is surface-modified.. ... Kyoto University

01/19/17 / #20170018795

Liquid electrolyte for fluoride ion battery and fluoride ion battery

. . The problem to be solved is to provide a liquid electrolyte for a fluoride ion battery which allows a larger capacity of the battery. Solving the problem by providing a liquid electrolyte for a fluoride ion battery including a fluoride salt and a solvent to dissolve the fluoride salt, characterized in that the solvent is an aromatic material having an aromatic cation and an anion, and a molar ratio of the aromatic cation to a fluoride ion is more than 1.. ... Kyoto University

01/19/17 / #20170016069

Method for testing for autosomal dominant polycystic kidney disease and method for screening agent for treatment of the disease

This invention provides a method of comparing disease markers obtained from subject samples to test for, detect, or diagnose autosomal dominant polycystic kidney disease and a disease marker for such disease. The method for detecting autosomal dominant polycystic kidney disease and the method for screening for an agent for treatment or prevention of such disease comprise detecting a gene that is expressed specifically in cases of autosomal dominant polycystic kidney disease, including igfbp7.. ... Kyoto University

01/19/17 / #20170015966

Spheroid-producing device, method for recovering spheroids, and method for producing spheroids

The present invention provides a device for producing a large number of uniform spheroids by an easy method. The spheroid-producing device (1) at least includes a first surface (11), a second surface (12), and a plurality of wall surfaces (13). ... Kyoto University

01/12/17 / #20170010256

Method for screening therapeutic and/or prophylactic agents for alzheimer's disease

The present invention provides a method for screening a therapeutic and/or prophylactic agent for alzheimer's disease using at least one index selected from the levels of aβ oligomers, bip, cleaved caspase 4, prdx4 and ros in nerve cells or the like whose differentiation has been induced from ips cells derived from somatic cells of a patient with alzheimer's disease.. . ... Kyoto University

01/12/17 / #20170009201

Culture medium composition

The present invention provides a culture method of cells and/or tissues including culturing cells and/or tissues in a suspended state by using a medium composition having an effect of preventing sedimentation of cells and/or tissues, which is afforded by substantially retaining the cells and/or tissues without substantially increasing the viscosity of the solution by nanofibers which have been added to the solution and uniformly dispersed in the liquid medium, and the like.. . ... Kyoto University

01/05/17 / #20170002311

Method for producing culture medium composition

The present invention provides a production method of a medium composition, including previously removing divalent metal cations contained in a polymer compound having an anionic functional group, preparing a dry powder of the polymer compound, and mixing the dry powder and the medium, and the like. The present invention also provides a purification method of a polymer compound having an anionic functional group, which includes mixing a suspension of the polymer compound having an anionic functional group in water and a cation exchanger that exchanges a divalent metal cation with a monovalent metal cation to give a polymer compound having an anionic functional group, which shows a reduced amount of contaminating divalent metal cations.. ... Kyoto University

01/05/17 / #20170002182

Puroduction method for readily dispersible cellulose composition, readily dispersible cellulose composition, cellulose dispersion resin composition, and prodaction method for water-based dispersant for cellulose

An object of the present invention is to provide a technology of dispersing cellulose readily in a hydrophobic substance such as a resin by treating cellulose being a hydrophilic substance in a system that contains water as a main medium with a polymer dispersant, which has been developed for dispersing a fine and hydrophobic substance such as a pigment, in a simple and efficient manner without conducting surface modification of nanocellulose or other treatments. The object is solved by a process for producing a readily dispersible cellulose composition, the process including dissolving a polymer dispersant having a block copolymer structure having a resin-affinitive segment a and a cellulose-adsorptive segment b in a hydrophilic organic solvent solution, adding a surface active agent to the resultant solution, thereafter adding water to the resultant mixture to prepare an aqueous dispersion treatment agent containing the polymer dispersant, and adding the obtained aqueous dispersion treatment agent to cellulose in a water-containing state or in a dry state, thereby obtaining a readily dispersible cellulose composition. ... Kyoto University

01/05/17 / #20170001162

Polymer dispersant for cellulose, aqueous dispersion treatment agent containing same, readily dispersible cellulose composition, cellulose dispersion resin composition, and dispersant-containing resin composition for cellulose dispersion

An object of the present invention is to provide a high-performance polymer dispersant that can be applied to cellulose being a hydrophilic substance, and another object of the present invention is to provide a technology for practical application of obtaining a cellulose-dispersed resin composition that realizes stable dispersion of cellulose in a simpler manner and in an environmentally conscious manner that never uses a large amount of organic solvents when the polymer dispersant for cellulose is applied to cellulose and disperses the cellulose in a thermoplastic resin. These objects are achieved by providing a polymer dispersant for cellulose, being a polymer compound including a block copolymer structure having a resin-affinitive segment a and a cellulose-adsorptive segment b, the polymer compound synthesized by a reversible chain transfer catalyzed polymerization (rtcp) method not using any of a heavy metal, a nitroxide compound, and a sulfur-based compound, using an organic iodine compound as an initiation compound, and using a phosphorus compound, a nitrogen compound, an oxygen compound, or a carbon compound as a catalyst.. ... Kyoto University








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