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Laboratoire Francais Du Fractionnement Et Des Biotechnologies patents


Recent patent applications related to Laboratoire Francais Du Fractionnement Et Des Biotechnologies. Laboratoire Francais Du Fractionnement Et Des Biotechnologies is listed as an Agent/Assignee. Note: Laboratoire Francais Du Fractionnement Et Des Biotechnologies may have other listings under different names/spellings. We're not affiliated with Laboratoire Francais Du Fractionnement Et Des Biotechnologies, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "L" | Laboratoire Francais Du Fractionnement Et Des Biotechnologies-related inventors


Composition enriched in anti-a and/or anti-b polyclonal immunoglobulins for use in the treatment of autoimmune diseases or polycythemia

The invention relates to a composition strongly enriched with anti-a and/or anti-b polyclonal immunoglobulins, comprising polyclonal human immunoglobulins, characterised in that at least 80 wt.-% of the polyclonal human immunoglobulins present in the composition are anti-a or anti-b polyclonal human immunoglobulins, for use as a drug, particularly in the treatment of polycythemia and/or autoimmune diseases, and in particular peripheral autoimmune thrombocytopenia.. . ... Laboratoire Francais Du Fractionnement Et Des Biotechnologies

Composition enriched in anti-a and /or anti b polyclonal immunoglobulins

The present invention relates to a composition highly enriched in anti-a and/or anti-b polyclonal immunoglobulins, comprising human polyclonal immunoglobulins, characterized in that at least 80% by weight of the human polyclonal immunoglobulins present in the composition are human anti-a and/or anti-b polyclonal immunoglobulins. The invention also relates to a method for preparing such a composition, and to the use of the composition for preparing a positive control that can be used in a method for assaying anti-a and/or anti-b activity of human normal immunoglobulins, and to use of the composition for determining an individual's blood type.. ... Laboratoire Francais Du Fractionnement Et Des Biotechnologies

Anti-cd303 monoclonal antibodies

The invention relates to chimeric or humanised anti-cd303 antibodies to nucleic acids coding for the heavy and light chains of these antibodies, expression vectors, host cells, transgenic non-human animals or transgenic plants expressing said antibodies, as well as to the uses thereof in the treatment or prevention of blastic plasmacytoid dendritic cell neoplasms (bpdcn) or inflammatory diseases, in particular autoimmune diseases, involving plasmacytoid dendritic cells.. . ... Laboratoire Francais Du Fractionnement Et Des Biotechnologies

Method for the purification of a therapeutic recombinant protein from transgenic milk

The invention relates to a method for the purification of a therapeutic protein from transgenic milk, comprising a clarification step using a salt of poly(diallyldimethylammonium).. . ... Laboratoire Francais Du Fractionnement Et Des Biotechnologies

Cell line overexpressing human cd303 antigen

The invention relates to a cell line expressing the gamma chain of the fcεri receptor and human cd303 antigen, characterised in that said cell line is transfected in a stable manner by an expression vector comprising a nucleic acid molecule coding for human cd303 antigen and having strong expression of human cd303 on the surface thereof, e.g. At least 10000 molecules of human cd303 per cell, as well as a vector or vector kit that can be used to co-express the gamma chain of the fcεri receptor and human cd303 antigen, and different uses of the cell line of the invention.. ... Laboratoire Francais Du Fractionnement Et Des Biotechnologies

Fc mutants with modified functional activity

Disclosed is to a polypeptide including a mutated fc region and having functional activity, mediated by the fc region, that is modified compared with that of a parent polypeptide. The fc region includes at least one combination of 2 mutations, the combination being selected from among one mutation selected from among a first set of mutations, and at least one mutation selected from among a second set of mutations, and provided that mutation (i) does not take place on the same amino acid as mutation (ii). ... Laboratoire Francais Du Fractionnement Et Des Biotechnologies

Monoclonal antibodies with enhanced adcc function

The invention concerns a method for obtaining and selecting monoclonal antibodies by an addc-type test, said antibodies capable of activating type iii fcy receptors and having a particular glycan structure. The inventive anti-d antibodies can be used for preventing rhesus isoimmunisation in rh negative persons, in particular for haemolytic disease in a new-born baby of for uses such as idiopathic thrombocytopenic pupura 9itp). ... Laboratoire Francais Du Fractionnement Et Des Biotechnologies

Combination of anti-cd20 antibody and pi3 kinase selective inhibitor

Highly effective combinations of a compound of formula a (a pi3kδ selective inhibitor) and anti-cd20 antibodies are provided herein for the treatment and amelioration of pi3kδ and/or cd20 mediated diseases and disorderes. In particular, the combination can be used to treat cancers and autoimmune diseases. ... Laboratoire Francais Du Fractionnement Et Des Biotechnologies

Method for preparing universal plasma

The present invention relates to an universal plasma, originating from a mixture of plasmas originating from donor individuals of blood groups a, b, ab and/or o and compatible with all the blood groups and the preparation process thereof.. . ... Laboratoire Francais Du Fractionnement Et Des Biotechnologies

Method for purification of monoclonal antibodies

Disclosed is a method for purification of monoclonal antibodies or of a fusion protein between the fc segment of an antibody and a second polypeptide, including a) an affinity chromatography step on a resin having as a matrix a crosslinked methacrylate polymer gel, on which the protein a is grafted, b) a viral inactivation step, c) a chromatography step exchanging cations on a resin having a crosslinked agarose gel matrix, on which sulfonate groups (—so3—) are grafted using dextran-based spacer arms, d) a chromatography step exchanging anions on a hydrophilic membrane of polyethersulfone coated with a crosslinked polymer on which quaternary amine groups (q) are grafted, and e) a nanofiltration step using a filter having an asymmetric polyethersulfone double membrane with a porosity of approximately 20 nm.. . ... Laboratoire Francais Du Fractionnement Et Des Biotechnologies

Recombinant proteins having factor h activity

The invention relates to a recombinant protein having factor h activity.. . ... Laboratoire Francais Du Fractionnement Et Des Biotechnologies

Packaging for a medicament used for innovative therapy

Disclosed is a product including: a) at least one substance selected from recombinant nucleic acids, single cells and single tissues, the compound being contained in a primary container; and b) a secondary container containing the primary container, the secondary container consisting of an insulating material. Also disclosed is a method for transporting a substance selected from recombinant nucleic acids, single cells and single tissues, which uses the product.. ... Laboratoire Francais Du Fractionnement Et Des Biotechnologies

Method for preparing human plasma proteins

The invention relates to a method for preparing plasma protein concentrate from blood plasma by means of multicolumn chromatography.. . ... Laboratoire Francais Du Fractionnement Et Des Biotechnologies








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