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Lund Inc patents


Recent patent applications related to Lund Inc. Lund Inc is listed as an Agent/Assignee. Note: Lund Inc may have other listings under different names/spellings. We're not affiliated with Lund Inc, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "L" | Lund Inc-related inventors


 new patent  Agents, uses and methods for the treatment of synucleinopathy

The invention relates to combinational treatment using a monoclonal anti-alpha-synuclein antibody and an additional medicament. The antibodies can be used for treating a synucleinopathy such as parkinson's disease (including idiopathic and inherited forms of parkinson's disease), diffuse lewy body disease (dlbd), lewy body variant of alzheimer's disease (lbv), combined alzheimer's and parkinson disease, pure autonomic failure and multiple system atrophy together with another medicament of the invention.. ... Lund Inc

 new patent  Pde9 inhibitors with imidazo triazinone backbone and imidazo pyrazinone backbone for treatment of peripheral diseases

The present invention relates to pde9 inhibitors and their use for treatment of benign prostate hyperplasia and sickle cell disease.. . ... Lund Inc

 new patent  Process feature graphical elements for medical treatment user interfaces

Graphical user interfaces for use with extracorporeal blood treatment systems may include one or more process feature graphical elements. The process feature graphical elements may be moved automatically or manually by users to provide indications with respect to the process features associated with and represented by the process feature graphical elements.. ... Lund Inc

 new patent  Apparatus for determining a parameter indicative of the progress of an extracorporeal blood treatment

An apparatus for extracorporeal treatment of blood (1) comprising a treatment unit, a blood withdrawal line, a blood return line, a preparation line and a spent dialysate line. A control unit (10) is configured to calculate values of a parameter relating to treatment effectiveness based on measures of the conductivity in the spent dialysate line. ... Lund Inc

 new patent  Treatment solution delivery in an extracorporeal blood treatment apparatus

Blood treatment apparatus and methods of using the same are described herein that include two or more intermediate containers located between a treatment solution source and a port through which the treatment solution is to be delivered with the blood treatment apparatus. The weight of the intermediate containers is measured and used to control the refilling and emptying of treatment solution in the intermediate containers.. ... Lund Inc

Human-shaped graphical element for medical treatment user interfaces

. . Graphical user interfaces for use with extracorporeal blood treatment systems may include a human-shaped graphical element and one or more process feature graphical elements. The human-shaped graphical element may be moved automatically or manually by users with respect to the process feature graphical elements to provide indications with respect to the process features corresponding to the human-shaped graphical element and the process feature graphical elements.. ... Lund Inc

Systems and methods including a human-shaped graphical element

Graphical user interfaces for use with extracorporeal blood treatment systems may include a human-shaped graphical element and one or more process feature graphical elements. The human-shaped graphical element may be moved automatically or manually by users with respect to the process feature graphical elements to provide indications with respect to the process features corresponding to the human-shaped graphical element and the process feature graphical elements.. ... Lund Inc

Methods and packaging for wet aging meat

Methods, packaging, and packets for wet aging meat are described herein. For example, in one or more embodiments of the present disclosure a package for wet aging meat includes a cut of meat having a fat layer portion and an edible meat portion, an adsorptive material to adsorb gases emitted from the cut of meat wherein the adsorptive material is positioned on the fat layer portion, a salt material positioned on the adsorptive material or on the fat layer portion with the adsorptive material, and wherein the cut of meat with the adsorptive material and salt material is sealed in a packaging material to form the package.. ... Lund Inc

Monoclonal anti-alpha-synuclein antibodies for preventing tau aggregation

The invention relates to a novel use of monoclonal anti-alpha-synuclein antibodies. The antibodies can be used to prevent tau aggregation and thereby treating tauopathies such as alzheimer's disease.. ... Lund Inc

Agents, uses and methods for the treatment of synucleinopathy

The invention relates to novel monoclonal anti-alpha-synuclein antibodies. The antibodies can be used for treating a synucleinopathy such as parkinson's disease (including idiopathic and inherited forms of parkinson's disease), diffuse lewy body disease (dlbd), lewy body variant of alzheimer's disease (lbv), combined alzheimer's and parkinson disease, pure autonomic failure and multiple system atrophy.. ... Lund Inc

Agents, uses and methods for the treatment of synucleinopathy

The invention relates to novel monoclonal anti-alpha-synuclein antibodies. The antibodies can be used for treating a synucleinopathy such as parkinson's disease (including idiopathic and inherited forms of parkinson's disease), diffuse lewy body disease (dlbd), lewy body variant of alzheimer's disease (lbv), combined alzheimer's and parkinson disease, pure autonomic failure and multiple system atrophy.. ... Lund Inc

Pyrazolo[3,4-b]pyridines and imidazo[1,5-b]pyridazines as pde1 inhibitors

The present invention provides compounds of formula (i) that are pde1 enzyme inhibitors and their use as a medicament, in particular for the treatment of neurodegenerative disorders and psychiatric disorders. The present invention also provides pharmaceutical compositions comprising compounds of the invention and methods of treating disorders using the compounds of the invention.. ... Lund Inc

Cyclic amines

The present invention is directed to novel cyclic amines which inhibit the p2x7 receptor.. . ... Lund Inc

Apparatus for extracorporeal blood treatment

An extracorporeal blood treatment apparatus is provided comprising a filtration unit (2) connected to a blood circuit (17) and to a dialysate circuit (32), a preparation device (9) for preparing and regulating the composition of the dialysis fluid, and a sensor (11) for measuring conductivity of the dialysate (i.e. Spent dialysis fluid); a control unit (12) configured for setting a sodium concentration in the dialysis fluid and after setting the dialysis fluid at the initial set point, circulating the dialysis fluid and blood through the filtration unit (2), measuring an initial conductivity value of the dialysate at the beginning of the treatment, and calculating, based on the measured initial conductivity value of the spent dialysis fluid and on the corresponding conductivity value of the dialysis fluid, the value of the initial plasma conductivity, said circulating the dialysis fluid up to the calculating of the initial plasma conductivity being performed maintaining the dialysis fluid conductivity substantially constant.. ... Lund Inc

06/21/18 / #20180168222

Container

A container comprising a base and a lid defining a first compartment therebetween for storing unused snus, wherein at least the lid or the base includes a reconfigurable wall to enable a user to form or enlarge a second compartment for storing used snus on the other side of said wall to the first compartment. The reconfigurable wall is formed of contiguous polygons configured to move relative to a boundary of the reconfigurable wall and relative to each other under applied pressure so as to be arrangeable in a first, convex configuration and arrangeable in a second, concave configuration. ... Lund Inc

06/07/18 / #20180155097

Container

A container comprising a base and a lid defining a first compartment therebetween for storing unused snus, wherein at least the lid or the base includes a separating element which is stretchable to enable a user to form or enlarge a second compartment for storing used snus on the other side of said separating element to the first compartment.. . ... Lund Inc

06/07/18 / #20180153881

Dosing regimens for fast onset of antidepressant effect

A dose regimes comprising the simultaneous administration of two pharmaceutical compositions, wherein the first pharmaceutical composition is a composition comprising vortioxetine or a pharmaceutically acceptable salt thereof for once daily oral administration, and the second pharmaceutical composition is a composition comprising vortioxetine or a pharmaceutically acceptable salt thereof which together with said first composition quickly achieves a steady-state plasma level of vortioxetine in said patient which steady-state plasma level is the same as the steady-state vortioxetine plasma level achieved by the administration to said patient of said first composition alone.. . ... Lund Inc

06/07/18 / #20180153797

Novel parenteral carbamazepine formulation

The present invention is directed to a carbamazepine-cyclodextrin inclusion complex useful for the parenteral administration of carbamazepine. The carbamazepine-cyclodextrin inclusion complex is prepared by the admixture of a modified cyclodextrin and carbamazepine in a physiologically acceptable fluid. ... Lund Inc

05/31/18 / #20180147335

Apparatus for performng an extracorporeal blood treatment

An extracorporeal blood treatment apparatus is provided comprising a filtration unit (2) connected to a blood circuit (17) and to a dialysate circuit (32); a control unit (12) is configured for calculating a sodium concentration value for the blood; the estimation of the sodium concentration includes the sub-step of calculating the sodium concentration value as an algebraic sum of a main contribution term based on the isoconductive sodium concentrate and of an offset contribution term based on a concentration of at least a substance in the dialysis fluid chosen in the group including bicarbonate, potassium, acetate, lactate, citrate, magnesium, calcium, sulphate and phosphate.. . ... Lund Inc

05/24/18 / #20180144817

Medical device system and method having a distributed database

A medical device system (10) including a distributed database (10a to 10f); a plurality of medical devices (12) operating with the distributed database (10a to 10f); and a logic implementer (20) associated with each medical device (12), wherein each logic implementer (20) is programmed to access the distributed database (10a to 10f), so that each medical device (12) of system (10) periodically (i) delivers at least one of prescription input parameters or treatment output data to and (ii) retrieves at least one of prescription input parameters or treatment output data from each of the other medical devices (12).. . ... Lund Inc

05/24/18 / #20180141497

Automated retractable vehicle step

Powered retractable vehicle step assist systems and methods are provided. The steps systems are configured for installation (e.g., after market installation) and use with a vehicle. ... Lund Inc

05/24/18 / #20180140761

Extracorporeal blood treatment apparatus

An extracorporeal blood treatment apparatus is provided comprising a filtration unit (2) connected to a blood circuit (17) and to a dialysate circuit (32), a preparation device (9) for preparing and regulating the composition of the dialysis fluid; a control unit (12) is configured for setting a sodium concentration value for the dialysis fluid in the dialysis supply line (8) at a set point; the setting of the sodium concentration includes the sub-step of calculating the sodium concentration value as an algebraic sum of a main contribution term based on the blood plasma conductivity and of an adjustment contribution term based on a concentration of at least a substance in the dialysis fluid chosen in the group including bicarbonate, potassium, acetate, lactate, citrate, magnesium, calcium, sulphate, and phosphate.. . ... Lund Inc

05/10/18 / #20180127492

Agents, uses and methods for the treatment of synucleinopathy

. . The invention relates to novel monoclonal anti-alpha-synuclein antibodies. The antibodies can be used for treating a synucleinopathy such as parkinson's disease (including idiopathic and inherited forms of parkinson's disease), diffuse lewy body disease (dlbd), lewy body variant of alzheimer's disease (lbv), combined alzheimer's and parkinson disease, pure autonomic failure and multiple system atrophy.. ... Lund Inc

05/10/18 / #20180127491

Agents, uses and methods for the treatment of synucleinopathy

The invention relates to novel monoclonal anti-alpha-synuclein antibodies. The antibodies can be used for treating a synucleinopathy such as parkinson's disease (including idiopathic and inherited forms of parkinson's disease), diffuse lewy body disease (dlbd), lewy body variant of alzheimer's disease (lbv), combined alzheimer's and parkinson disease, pure autonomic failure and multiple system atrophy.. ... Lund Inc

05/10/18 / #20180126062

Detection of a disruption of a fluid connection between two fluid containing systems

A monitoring system (9) performs a method for detecting a disruption of a fluid connection between a first fluid containing system and a second fluid containing system. The monitoring system generates a monitoring signal (m1) which is representative of a fluid pressure in respect of the first fluid containing system and which is responsive to the disruption of the fluid connection, and a tracking signal (t1) which corresponds to and is more smoothed over time than the monitoring signal (m1). ... Lund Inc

05/10/18 / #20180125835

Dosage and use of an a2a antagonist

The present invention relates to specific dosages of an a2a antagonist for use as a medicament and in particular useful for the treatment of parkinson disease and attention deficit/hyperactivity disorder.. . ... Lund Inc

05/10/18 / #20180125557

Mixing and dispensing gun

A device for mixing and dispensing a paste, such as bone cement, comprises a housing (h) with a feeding mechanism (53), and a cylinder (51) for mixing a powder component and a liquid component forming the paste. A piston assembly includes a paste feeding member (57) located in the cylinder, and a tubular member (54). ... Lund Inc

05/03/18 / #20180118283

Adjustable spare tire carrier

Disclosed herein are embodiments of a spare tire carrier for a vehicle that can be adjustable for moving the spare tire into different positions. The spare tire carrier can be attached to existing components of a vehicle in order to move the spare tire's position, which can be advantageous for avoiding environmental hazards when off-roading.. ... Lund Inc

03/29/18 / #20180086273

Retractable vehicle step

A retractable step for use with a vehicle comprises a stepping member having an upper stepping surface, a first arm, and a second arm. The first arm has a first end pivotally attached to the vehicle, and a second end pivotally attached to the stepping member. ... Lund Inc

03/29/18 / #20180085512

Filtering a pressure signal from a pressure sensor in a blood processing apparatus

A signal filtering device acquires a pressure signal from a pressure sensor in a blood processing apparatus having a known disturbance generator that generates a disturbance in the pressure signal. The signal filtering device obtains (401) a current set of principal components representing the disturbance. ... Lund Inc

03/22/18 / #20180079366

Loft storage and equipment compartment

A compact safe storage compartment for weapons and electronic equipment, also sometime referred to as loft, for police sports utility vehicles (suvs) is provided which is easy to use and access by police and is not readily viewable from outside the suv by pedestrians, criminals and others. The loft can occupy otherwise unused space in the suv. ... Lund Inc

03/15/18 / #20180075203

Medical treatment device with speaker sound detection

Medical treatment devices and methods may include a speaker operable to broadcast one or more types of sounds, wherein each type of sound may be associated with a predefined sound signature. An acoustic transducer may be used to generate a sound signal representative of a sound when broadcast by the speaker. ... Lund Inc

03/15/18 / #20180071450

Treatment system with infusion apparatus pressure priming

A system or method includes an infusion apparatus controllable to provide a fluid flow from a replaceable fluid dispenser at a set flow rate. The infusion apparatus may be commanded to operate on a replacement fluid dispenser to provide one or more boluses of the plurality of boluses into an infusion line. ... Lund Inc

03/15/18 / #20180071254

Methods of treating dementia and pharmaceutical compositions thereof

The present invention describes methods of treating dementia comprising administering an effective daily dose of n-[2-(6-fluoro-1h-indol-3-yl)ethyl]-3-(2,2,3,3-tetrafluoropropoxy)benzylamine to improve or augment the effect of an acetylcholinesterase inhibitor.. . ... Lund Inc

03/08/18 / #20180065984

Manufacture of 4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridin-3-ol

The present invention relates to a process for synthesis of 4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridin-3-ol abbreviated thip, having the inn name gaboxadol, starting from pyrrolidin-2-one. The process comprises a new direct process to obtain the intermediate dimethyl 5-hydroxy-3,6-dihydropyridine-1,4(2h)-5 dicarboxylate or the intermediate diethyl 5-hydroxy-3,6-dihydropyridine-1,4(2h)-dicarboxylate.. ... Lund Inc

03/01/18 / #20180055989

Controlling an apparatus for fluid transfer to and/or from a subject

A control system (23) is arranged to control the operation of an apparatus (200) for extracorporeal blood treatment. The apparatus (200) comprises an extracorporeal blood circuit (20) and a connection system (c) for connecting the blood circuit (20) to the vascular system of a patient. ... Lund Inc

02/22/18 / #20180050062

Dialysis precursor composition product

The present invention concerns a dialysis acid precursor composition for use during preparation of a dialysis acid concentrate solution and for mixing with water, a sodium containing concentrate, and a bicarbonate containing concentrate into a ready-for-use dialysis solution. The dialysis acid precursor composition consists of powder components comprising glucose, at least one dry acid and at least one magnesium salt, and optionally potassium salt, and calcium salt. ... Lund Inc

02/01/18 / #20180028526

Nalmefene for reduction of alcohol consumption in specific target populations

The present invention relates to nalmefene for use in the reduction of alcohol consumption in a patient with alcohol dependence who has a high drinking risk level. The present invention also relates to nalmefene for use in the reduction of alcohol consumption in a patient with alcohol dependence who maintains a high drl after an observation period following initial assessment.. ... Lund Inc

01/25/18 / #20180022505

Packaging container for scoopable contents

A packaging container for scoopable bulk solids comprising a container body includes a container wall extending from a container bottom edge to a container body opening in a height direction of the container, and a closure arrangement including a lid. The container wall has an inner surface facing towards an inner compartment in the packaging container and an outer surface facing away from the inner compartment. ... Lund Inc

01/25/18 / #20180020876

Packaging container with rim and lid

A paperboard packaging container for bulk solids includes a container body having a container wall extending from a container bottom edge to a container body opening and having an inner surface facing an inner compartment in the packaging container, and a lid for closing the container body opening. An upper reinforcing rim is applied at the container body opening and extends along the opening edge, defining a perimeter of a container access opening and is joined to the inner surface of the container wall by means of a weld seal which extends around the container body opening and has an upper edge including a first abutment surface arranged to abut against a second abutment surface on an inner lid surface with the lid in a closed position on the container access opening and form a tight seal between the rim and the lid with the lid in the closed position.. ... Lund Inc

01/18/18 / #20180016330

Antibodies specific for hyperphosphorylated tau and methods of use thereof

The present invention relates to a class of monoclonal antibody that specifically binds the phosphorylated serine 396 residue on pathological hyperphosphorylated (phf) tau (ps396) with improved affinity, as well as to methods of using these molecules and their tau binding fragments in the treatment of alzheimer's disease and other tauopathies.. . ... Lund Inc

01/18/18 / #20180016056

Paperboard packaging container for bulk solids

A paperboard packaging container for bulk solids includes a container body formed by a container wall having wall portions, and a container bottom. The wall portions are connected by corner portions and each wall portion extends in a height direction from a lower end edge at the container bottom to an upper end edge at a container opening, the height direction being perpendicular to a cross direction of the container. ... Lund Inc

01/18/18 / #20180016038

Method of producing and filling a packaging container

A method of producing and filling a paperboard packaging container with pulverulent bulk solids includes forming a tubular container body from a paperboard sheet, the body having upper and lower body openings and a container wall extending between the upper and lower body openings and having inner and outer surfaces; closing the upper body opening with a sealing membrane attached to the inner surface; providing an upper reinforcing rim; inserting at least a lower part of the upper reinforcing rim into the tubular container body at the upper body opening; forming a weld seal between the inner surface and the inserted part of the upper reinforcing rim; presenting the body to a filling station with the bottom body opening of the container body directed upward in a vertical direction; filling pulverulent material into the body through the upwardly directed bottom body opening; and closing the bottom body opening.. . ... Lund Inc

01/11/18 / #20180008761

Packaging of powdery material for preparation of a medical solution

A package (1) is configured to store a powdery material (2) which is to be mixed with a solvent to form a medical solution, such as a dialysis solution. The package (1) comprises a filled cavity portion (6a) containing the powdery material (2), optionally separated into groups of different composition, and a tab portion (9) integrally formed with the filled cavity portion (6a) and being swept around the filled cavity portion (6a) so as to define a roll-up package. ... Lund Inc

01/04/18 / #20180000815

Dosing regimens for fast onset of antidepressant effect

A dose regimes comprising the simultaneous administration of two pharmaceutical compositions, wherein the first pharmaceutical composition is a composition comprising vortioxetine or a pharmaceutically acceptable salt thereof for once daily oral administration, and the second pharmaceutical composition is a composition comprising vortioxetine or a pharmaceutically acceptable salt thereof which together with said first composition quickly achieves a steady-state plasma level of vortioxetine in said patient which steady-state plasma level is the same as the steady-state vortioxetine plasma level achieved by the administration to said patient of said first composition alone.. . ... Lund Inc

01/04/18 / #20180000786

1h-pyrazolo[4,3-b]pyridines as pde1 inhibitors

The present invention provides 1h-pyrazolo[4,3-b]pyridin-7-amines of formula (i) as pde1 inhibitors and their use as a medicament, in particular for the treatment of neurodegenerative disorders and psychiatric disorders.. . ... Lund Inc

12/28/17 / #20170369108

Tailgate reinforcement

Disclosed herein are embodiments of a reinforcement or brace that can be installed on the tailgate of a vehicle. The reinforcement can provide structural support for heavier mounted objects, such as tires, as well as allowing for different attachment points. ... Lund Inc

12/28/17 / #20170368507

On-line drying of hollow fiber membranes

The present invention relates to a continuous process for preparing permselective hollow fiber membranes being suitable e.g. For hemodialysis, hemodiafiltration and hemofiltration of blood which comprises a two-stage drying and tempering treatment of the hollow fiber membranes. ... Lund Inc

12/21/17 / #20170364649

Apparatus, process and system for monitoring a plurality of patients affected by kidney failure

An apparatus, a process and a system for monitoring a plurality of patients (p) affected by kidney failure over a time frame (t) are disclosed. The system includes blood treatment units, laboratory storage units, at least one hub module, and client units. ... Lund Inc

12/21/17 / #20170360777

1-[2-(2,4-dimethylphenylsulfanyl)-phenyl]piperazine as a compound with combined serotonin reuptake, 5-ht3 and 5-ht1a activity for the treatment of cognitive impairment

1-[2-(2,4-dimethylphenylsulphanyl)phenyl)]piperazine exhibits potent activity on sert, 5-ht3 and 5-ht1a and may as such be useful for the treatment of cognitive impairment, especially in depressed patients.. . ... Lund Inc

12/14/17 / #20170355335

Vehicle shield

A vehicle shield is provided according to the invention. The vehicle shield is constructed to avoid excessive hood flutter. ... Lund Inc

12/14/17 / #20170355315

Retractable vehicle step

A retractable vehicle step is attachable to a vehicle or truck, such as at the rear portion. The vehicle step facilitates access to a cargo hold of the vehicle. ... Lund Inc

11/30/17 / #20170340800

Infusion site for improved mixing of fluids

The invention relates to a blood line (108) comprising an infusion site (145) intended to inject into the line a solution comprising: —a first main channel (200) having a first passage section, —a second main channel (220) having a second passage section, —means for the formation (210) of a turbulence area located downstream from the first main channel, located upstream from the second main channel, these formation means comprising a first fluid passage means (224) defining a reduction (225) in the passage section and whose smallest passage section is smaller than the first passage section and smaller than the second fluid passage section, —a secondary channel (230) comprising an inlet (231) for letting in the solution and an outlet (232) in fluid communication with the first main channel or the means for the formation of a turbulence area or the second main channel.. . ... Lund Inc

11/30/17 / #20170340618

2-amino-5,5-difluoro-6-(fluoromethyl)-6-phenyl-3,4,5,6-tetrahydropyridines as bace1 inhibitors

The present invention is directed to compounds of formula (i) which are inhibitors of the bace1 enzyme. Separate aspects of the invention are directed to pharmaceutical compositions comprising said compounds and uses of the compounds to treat disorders for which the reduction of aβ deposits is beneficial such as alzheimer's disease.. ... Lund Inc

11/23/17 / #20170334614

Packaging container comprising a locking arrangement

A packaging container for bulk solids includes a container body, a container lid and a locking arrangement. The container body comprises a container wall that defines a container opening and an inner compartment. ... Lund Inc

11/23/17 / #20170333616

Apparatus and method of controlling an extracorporeal blood treatment

An apparatus is described for extracorporeal blood treatment, comprising a treatment unit, an extracorporeal blood circuit and a fluid evacuation line. The apparatus comprises a control unit connected to a pressure sensor and a blood pump, the blood pump generating a variable flow with a constant component and a variable component. ... Lund Inc

11/16/17 / #20170327279

Container with display function

The present invention provides a packaging container for bulk solids, the container comprising a container body and a container lid. The container body includes wall portions that define a container opening. ... Lund Inc

11/16/17 / #20170327159

Vehicle cargo tailgate enclosure

An improved vehicle cargo tailgate enclosure particularly adapted for ease of installation and removal. The tailgate enclosure comprises two side walls and a rear wall. ... Lund Inc

11/16/17 / #20170326107

5-ht6 receptor antagonists for use in the treatment of alzheimer's disease with apathy as comorbiity

The present invention relates to 5-ht6 receptor antagonists for the treatment of alzheimer's disease with comorbid apathy comprising administering an effective dose of a 5-ht6 receptor antagonist to improve or augment the effect of an acetylcholinesterase inhibitor.. . ... Lund Inc

11/09/17 / #20170319771

Apparatus for extracorporeal blood treatment and a control method therefor

An apparatus is described for extracorporeal blood treatment, comprising a treatment unit, an extracorporeal blood circuit and a fluid evacuation line. The apparatus comprises a control unit connected to a pressure sensor and configured to move a blood pump, generating a variable flow with a constant component equal to a desired blood flow value and a variable component having a nil mean value; the variable flow generates, in the expansion chamber, a pressure progression that is variable over time with a pressure component oscillating about a mean value. ... Lund Inc

11/09/17 / #20170319770

Systems and methods for peritoneal dialysis having point of use dialysis fluid preparation including mixing and heating therefore

A peritoneal dialysis system includes a cycler including a pump actuator, a heater and a heating pan operable with the heater, and a disposable set operable with the cycler. The heating pan includes a sidewall forming a slot. ... Lund Inc

11/09/17 / #20170319769

Systems and methods for peritoneal dialysis having point of use dialysis fluid preparation including testing thereof

A peritoneal dialysis system includes a disposable set, source(s) of concentrate(s), a water purifier, a sensor, and a control unit. The disposable set includes a water port, an inlet port, a drain port, a water line in fluid communication with the water port, a drain line in fluid communication with the drain port, and a container to hold a dialysis fluid prepared by mixing water and the concentrate(s). ... Lund Inc

11/09/17 / #20170319768

Systems and methods for peritoneal dialysis having point of use dialysis fluid preparation using water accumulator and disposable set

A peritoneal dialysis system includes a water purifier, a cycler, and a disposable set operable with the cycler. The disposable set includes a pumping cassette including a water inlet port, a heater/mixing container in fluid communication with the pumping cassette, a water accumulator, a first water line segment, and a second water line segment. ... Lund Inc

11/09/17 / #20170319564

2-amino-6-(difluoromethyl)-5,5-difluoro-6-phenyl-3,4,5,6-tetrahydropyridines as bace1 inhibitors

The present invention is directed to compounds of formula (i) which are inhibitors of the bace1 enzyme. Separate aspects of the invention are directed to pharmaceutical compositions comprising said compounds and uses of the compounds to treat disorders for which the reduction of aβ deposits is beneficial such as alzheimer's disease.. ... Lund Inc

10/26/17 / #20170306822

Tank cover for diesel exhaust fluid tank

Embodiments of a tank cover for covering a diesel exhaust fluid tank of a vehicle. The tank cover can be added directly over a diesel exhaust fluid tank or can be used to replace a factory/oem or other replacement cover. ... Lund Inc

10/26/17 / #20170304267

Use of an acetylcholinesterase inhibitor and idalopirdine for reducing falls in parkinson's disease patients

The present invention relates to the use of an acetylcholinesterase inhibitor and idalopirdine for reducing falls in patients suffering from a cns disease, in particular patients with parkinson's disease, wherein balance, gait or movement is impaired.. . ... Lund Inc

10/12/17 / #20170291903

Imidazopyrazinones as pde1 inhibitors

The present invention provides imidazopyrazinones as pde1 inhibitors and their use as a medicament, in particular for the treatment of neurodegenerative disorders and psychiatric disorders.. . ... Lund Inc

10/12/17 / #20170291901

1,5-dihydro-4h-pyrazolo[3,4-d]pyrimidin-4-ones and 1,5-dihydro-4h-pyrazolo[4,3-c]pyridin-4-ones as pde1 inhibitors

The present invention provides 1,5-dihydro-4h-pyrazolo[3,4-d]pyrimidin-4-ones and 1,5-dihydro-4h-pyrazolo[4,3-c]pyridin-4-ones of formula (i) as pde1 inhibitors and their use as a medicament, in particular for the treatment of neurodegenerative disorders and psychiatric disorders.. . ... Lund Inc

10/12/17 / #20170291874

Process for the manufacture of idalopirdine via hydrogenation of an imine

The present invention relates to the preparation of n-(2-(6-fluoro-1h-indol-3-yl)-ethyl)-3-(2,2,3,3-tetrafluoropropoxy)-benzylamine (compound i), inn-name idalopirdine, and pharmaceutically acceptable salts thereof:. . ... Lund Inc

09/28/17 / #20170275294

Nalmefene salts as medicaments for reducing alcohol consumption or for preventing excessive alcohol consumption

The present invention relates to new nalmefene salts which salts fall within at least one of the two following categories: non-hydrate forming salts and non-solvate forming salts. In particular, the invention relates to the hydrogen adipate salt, the hydrogen malonate salt, the lactate salt, the hydrogen fumarate salt, the hydrogen succinate salt, the benzene sulfonate salt, the hydrogen maleate salt and the salicylate salt of nalmefene. ... Lund Inc

09/21/17 / #20170267761

Agents, uses and methods for treatment

The present invention relates to monoclonal anti-sortilin antibodies which have been found useful in correcting a deficient level of progranulin (pgrn). In particular, these antibodies can be used in the treatment of frontotemporal dementia (ftd) and amyotrophic lateral sclerosis (als).. ... Lund Inc

09/21/17 / #20170267664

Quinazolin-thf-amines as pde1 inhibitors

The present invention provides quinazolin-thf-amines as pde i inhibitors and their use as a medicament, in particular for the treatment of neurodegenerative disorders and psychiatric disorders.. . ... Lund Inc

09/21/17 / #20170267182

Retractable vehicle step

A retractable step for use with a vehicle comprises a stepping member having an upper stepping surface, a first arm, and a second arm. The first arm has a first end pivotally attached to the vehicle, and a second end pivotally attached to the stepping member. ... Lund Inc

09/14/17 / #20170258976

Method of displaying a predicted state, medical apparatus and computer program

A method of displaying a predicted state of a medical apparatus, and a medical apparatus employing the method are disclosed. The method comprises receiving a sensor signal from a sensor of the medical apparatus, filtering the sensor signal by an adaptive filter such that a predicted signal is achieved, determining a state from the predicted signal, and displaying an indication through a user interface of the medical apparatus based on the determined state.. ... Lund Inc

09/07/17 / #20170252501

Apparatus for extracorporeal treatment of blood and method of control of a blood-warming device in an extracorporeal blood treatment apparatus

An extracorporeal blood treatment apparatus (1) comprising a control unit (10) connectable to a blood warming device (200). The apparatus (1) comprises: an extracorporeal blood circuit (100) and at least one infusion line (15, 21, 25) connected to the extracorporeal blood circuit (100). ... Lund Inc

08/31/17 / #20170248610

Method of predicting obesity

The presently disclosed subject matter relates to a method for predicting increased risk of obesity on a non-obese subject. More particularly, the presently disclosed subject matter relates to a method of predicting increased risk of obesity in a non-obese subject by determining a level of neurotensin expression in a biological sample from the subject and comparing the level of neurotensin expression in the sample with a control level. ... Lund Inc

08/31/17 / #20170246993

Horizontal retractable vehicle step

A horizontally moving retractable vehicle step is attachable to a vehicle, such as a low to the ground vehicle like a van. The horizontal vehicle step can provide access to different portions of the vehicle. ... Lund Inc

08/24/17 / #20170240611

Modulation of the vps10p-domain receptor family for the treatment of mental and behavioural disorders

. . The present invention relates to methods for modulating the activity of one or more vps10p-domain receptors selected from the group consisting of sortilin, sorla, sorcs1, sorcs2 and sorcs3, in an animal and methods for preparation of a medicament for the treatment of mental and behavioral disorders. The modulation is carried out by inhibiting or promoting the binding of ligands to the vps10p-domain receptor. ... Lund Inc

08/24/17 / #20170239412

Method for establishing a wireless communication between a fluid processing medical device and a medical accessory, fluid processing medical device and system comprising a fluid processing medical device and medical accessory configured for establishing a wireless communication

A method of establishing a wireless operating communication between the extracorporeal blood treatment device and a medical accessory and extracorporeal blood treatment device configured for implementing the method are provided; the method comprises the steps of establishing a wireless auxiliary communication between the blood treatment device and the medical accessory, transferring configuration data using the wireless auxiliary communication and establishing the wireless operating communication between the blood treatment device and the medical accessory based on the configuration data. A maximum operating distance of the wireless auxiliary communication is shorter than a maximum operating distance of the wireless operating communication.. ... Lund Inc

08/17/17 / #20170237467

Method for providing operation data to a fluid processing medical apparatus using a medical accessory and a medical accessory

A method for providing operation data to a fluid processing medical apparatus and a medical accessory have been provided. The method comprises the steps of providing the medical apparatus (10) with a readable element (12); acquiring configuration data associated to the readable element (12) of the medical apparatus (10) by relatively approaching a data acquisition unit (22) of a medical accessory (20) and the readable element (12) of the medical apparatus (10); establishing a wireless communication between medical accessory (20) and the medical apparatus (10) based on the configuration data; providing a medical component (40) having a readable element (42); acquiring operation data associated to the readable element (42) of the medical component (40) by relatively approaching the data acquisition unit (22) of the medical accessory (20) and the readable element (42) of the medical component (40), the medical component (40) being destined to be operatively coupled to the medical apparatus (10); and providing the operation data to the medical apparatus (10) using the wireless communication.. ... Lund Inc

08/10/17 / #20170224677

Liquid formulations of salts of 1-[2-(2,4-dimethylphenylsulfanyl)phenyl]-piperazine

Liquid formulations of lactic acid addition salts of 1-[2-(2,4-dimethylphenylsulfanyl)-phenyl]piperazine are provided.. . ... Lund Inc

07/27/17 / #20170209637

Extracorporeal blood treatment alarm docking

. . Extracorporeal blood treatment systems and methods to display information related to an alarm issued during extracorporeal blood treatments. For example, when an alarm is issued, an alarm region may be depicted on a graphical user interface. ... Lund Inc

07/27/17 / #20170209636

Filter module

The present disclosure relates to a filter module for a medical fluid delivery system capable of removing cytokine inducing substances (cis) from a medical fluid.. . ... Lund Inc

07/27/17 / #20170209635

Medical apparatus for the preparation of medical fluid

A medical apparatus for the preparation of medical fluid is disclosed, comprising a support structure, a movable member, biasing means, and locking means. The movable member is mounted to the support structure and the biasing means are configured to operate in at least one of a repulsion mode and an attraction mode in the repulsion mode, the biasing means exert on the movable member a biasing force directing the movable member away from its retracted configuration, and in the attraction mode, the biasing means exert on the movable member a biasing force directing the movable member towards its retracted configuration. ... Lund Inc

07/13/17 / #20170196907

Dialysis formulation

. . A replacement fluid for dialysis treatment includes selenium in a concentration of 0.6-1.8 μm, and rubidium in a concentration of 1.4-4.2 μm. The replacement fluid is essentially free of one or more of the trace elements selected from chromium, manganese, and copper.. ... Lund Inc

07/06/17 / #20170190308

Retractable step and side bar assembly for raised vehicle

A retractable step and side bar assembly that can be used for raised vehicles, such as trucks. The retractable step can be configured to provide for significant reach in a deployed position to allow for a user to enter the raised vehicle. ... Lund Inc

06/22/17 / #20170173073

Dialysis precursor composition

. . A dialysis acid precursor assembly including: a bicarbonate containing concentrate and a dialysis acid concentrate solution including powder components mixed with water. The powder components include (1) a sodium chloride powder, (2) at least one dry acid powder, and (3) a magnesium chloride 4.5-hydrate (mgc12.4.5h2o) powder in a quantity such that a concentration of about 7.5-50 mm magnesium ions is provided in the dialysis acid concentrate solution.. ... Lund Inc

06/15/17 / #20170165616

Membrane for blood purification

The present disclosure relates to semipermeable membranes which are suitable for blood purification, e.g. By hemodialysis, which have an increased ability to remove larger molecules while at the same time effectively retaining albumin. ... Lund Inc

06/15/17 / #20170165615

Hemodialyzer for blood purification

The present disclosure relates to a dialyzer comprising a bundle of semipermeable hollow fiber membranes which is suitable for blood purification, wherein the dialyzer has an increased ability to remove larger molecules while at the same time it is able to effectively remove small uremic toxins and efficiently retain albumin and larger proteins. The invention also relates to using said dialyzer in hemodialysis.. ... Lund Inc

06/08/17 / #20170158766

Modulation of activity of neurotrophins

The present invention relates to methods for modulating the activity of one or more neurotrophins, such as neural growth factor (ngf), brain derived neurotrophic factor (bdnf), neurotrophin-3, and neurotrophin-4 (nt-4), in an animal and methods for treatment of a disease or disorder in an individual by modulation of neurotrophin activity. The modulation is carried out by interfering with binding between a neurotrophin and a receptor of the vps10p-domain receptor family or modulating the expression of a receptor of the vps10p-domain receptor family. ... Lund Inc

06/08/17 / #20170158650

Deuterated 1-piperazino-3-phenyl indanes for treatment of schizophrenia

The present invention relates to deuterated 1-piperazino-3-phenyl-indanes and salts thereof with activity at dopamine receptors d1 and d2 as well as the 5ht2 receptors in the central nervous system, to medicaments comprising such compounds as active ingredients, to the use of such compounds in the treatment of diseases in the central nervous system, and to methods of treatment comprising administration of such compounds.. . ... Lund Inc

06/08/17 / #20170157622

System, apparatuses, and methods for improving the operation of a turbine by using electrostatic precipitation

Embodiments of the invention involve the application of a disk-in-tube type of “wet” or “dry” esp (electrostatic precipitation) technology for the capture/removal of airborne particles entering a gas turbine compressor. This provides an effective method of particulate removal without the inefficiencies associated with conventional filtering techniques. ... Lund Inc

06/08/17 / #20170157172

Dialysis precursor composition

The present invention concerns a dialysis acid precursor composition for use during preparation of a dialysis acid concentrate solution and for mixing with water and a bicarbonate containing concentrate into a ready-for-use dialysis solution. The dialysis acid precursor composition consists of powder components comprising sodium chloride, at least one dry acid and at least one calcium salt, and optionally potassium salt, magnesium salt, and glucose. ... Lund Inc

06/01/17 / #20170152227

Novel polymorphic form of n-[2-(6-fluoro-lh-indol-3-yl)ethyl]-3-2,2,3,3-tetrafluoropropoxy)benzylamine hydrochoride for the treatment of alzheimer's

The present invention relates to a novel polymorphic form of n-[2-(6-fluoro-1h-indol-3-yl)ethyl]-3-(2,2,3,3-tetrafluoropropoxy)benzylamine hydrochloride.. . ... Lund Inc

05/11/17 / #20170128460

Cyclic amines

The present invention is directed to novel cyclic amines which inhibit the p2x7 receptor.. . ... Lund Inc

05/04/17 / #20170120731

Vehicle hood shield and bracket system

Disclosed herein are embodiments of a vehicle hood shield for use in protecting a vehicle hood from damage while the vehicle is in motion. The vehicle hood shield can be attached through the use of different adhesive taping configurations. ... Lund Inc

03/30/17 / #20170087968

Tonneau cover and method of attachment

A tonneau cover and a method of attachment are disclosed herein. In some embodiments, a self-energizing clamp can be used to retain a tonneau cover onto a side wall of a truck bed, or other vehicle bed. ... Lund Inc

03/23/17 / #20170081333

Pde9 inhibitors with imidazo triazinone backbone

This invention is directed to compounds, which are pde9 enzyme inhibitors. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. ... Lund Inc

03/23/17 / #20170079967

New positive allosteric modulators or nicotinic acetylcholine receptor

The present invention relates to compounds useful in therapy, to compositions comprising said compounds, and to methods of treating diseases comprising administration of said compounds. The compounds referred to are positive allosteric modulators (pams) of the nicotinic acetylcholine α7 receptor.. ... Lund Inc

03/09/17 / #20170066741

2-amino-3,5,5-trifluoro-3,4,5,6-tetrahydropyridines as bace1 inhibitors for treatment of alzheimer's disease

The present invention is directed to novel inhibitors of the bace1 enzyme. Separate aspects of the invention are directed to pharmaceutical compositions comprising said compounds and uses of the compounds to treat disorders for which the reduction of aβ deposits is beneficial such as alzheimer's disease.. ... Lund Inc

03/09/17 / #20170065760

Apparatus for extracorporeal blood treatment

An apparatus for extracorporeal blood treatment, comprising a treatment unit (2) having a first chamber (3) and a second chamber (4) separated from one another by a semipermeable membrane (5), a blood removal line (6) connected in inlet with the first chamber (3) and a blood return line (7) connected in outlet with the first chamber; an infusion line (9; 9a, 9b) of a replacement fluid and a fluid evacuation line (10) connected in outlet from the second chamber. A regulating device (20) of a transmembrane pressure is active on at least one of the lines and a control unit (15) is configured to: command the regulating device (20) by setting a first increase (δtmp1), determine a value of a control parameter (φ1) corresponding to the first increase, compare the value of the control parameter (φ1) with a reference value (φref) and, if the value of the control parameter is greater than the reference value, command the regulating device (20) by setting a second increase (δtmp2) which is greater than the first increase (δtmp1).. ... Lund Inc

02/23/17 / #20170051268

Non-neurotoxic plasminogen activating factors for treating of stroke

The invention concerns the use and the production of non-neurotoxic plasminogen activating factors, derived, for example, from the common vampire desmodus rotundus (dspa), for therapeutic treatment of stroke in humans. The invention provides a novel therapeutic base for treating stroke in humans.. ... Lund Inc

02/23/17 / #20170049948

Multipart fluid system and a system for regional citrate anticoagulation in an extracorporeal blood circuit

A method of treating blood withdrawn from patient including: simultaneously withdrawing blood and infusing withdrawn blood from and to the patient by flowing the withdrawn blood through an extracorporeal dialysis circuit including a dialyzer having a semi-permeable dialysis membrane and a dialysate side adjacent the membrane; feeding a dialysate containing 1 to 5 mm total calcium and 2 to 8 mm citrate to the dialysate side of the dialyzer, and introducing an anticoagulation fluid including at least 8 mm citrate into the. . ... Lund Inc

02/16/17 / #20170043299

Uv-irradiated hollow fiber membranes

. . . . The present invention relates to porous hollow fiber membranes suitable for hemodialysis, hemodiafiltration or hemofiltration of blood and processes for their production involving uv irradiation of the membrane.. . ... Lund Inc

02/16/17 / #20170042887

Combination of brexpiprazole and nalmefene and use thereof for treating substance-related disorders

A medicament comprising (i) brexpiprazole or a pharmaceutically acceptable salt thereof, and (ii) nalmefene or a pharmaceutically acceptable salt thereof in combination, wherein brexpiprazole or a pharmaceutically acceptable salt thereof, and nalmefene or a pharmaceutically acceptable salt thereof are contained in a single preparation, or a pharmaceutical composition containing brexpiprazole or a pharmaceutically acceptable salt thereof and a pharmaceutical composition containing nalmefene or a pharmaceutically acceptable salt thereof are formulated for use in combination. The medicament is used for the prophylaxis or treatment of a substance-related disorder, preferably an alcohol-related disorder.. ... Lund Inc

02/09/17 / #20170037006

Crystalline forms of 4-[2-(4-methylphenylsulfanyl)-phenyl] piperidine

Crystalline forms of 4-[2-(4-methylphenylsulfanyl)-phenyl]piperidine and salts thereof are provided, e.g., for the treatment of neuropathic pain.. . ... Lund Inc

02/02/17 / #20170028354

Thermoforming of fiber bundles

The invention relates to processes for the production of capillary dialyzers. The processes involve thermoforming of bundles of hollow fiber membranes. ... Lund Inc

01/26/17 / #20170022268

Antibodies specific to pyroglutamated abeta

The present invention relates to antibodies specific for pyroglutamated aβ, as well as their use in the treatment of alzheimer's disease and as use in diagnostic methods or as diagnostic imaging ligands. Further, is provided pyroglutamated n-terminal fragments of murine or human aβ to generate antibodies and for use in therapeutic purposes.. ... Lund Inc

01/26/17 / #20170022186

Halogenated quinazolin-thf-amines as pde1 inhibitors

The present invention provides halogenated quinazolin-thf-amines as pde1 inhibitors and their use as a medicament, in particular for the treatment of neurodegenerative disorders and psychiatric disorders.. . ... Lund Inc

01/19/17 / #20170015739

Agents, uses and methods for the treatment of synucleinopathy

The invention relates to novel monoclonal anti-alpha-synuclein antibodies. The antibodies can be used for treating a synucleinopathy such as parkinson's disease (including idiopathic and inherited forms of parkinson's disease), diffuse lewy body disease (dlbd), lewy body variant of alzheimer's disease (lbv), combined alzheimer's and parkinson disease, pure autonomic failure and multiple system atrophy.. ... Lund Inc

01/19/17 / #20170015738

Antibodies specific for hyperphosphorylated tau and methods of use thereof

The present invention relates to a novel class of monoclonal antibody that specifically binds the phosphorylated serine 396 residue on pathological hyperphosphorylated (phf) tau (ps396), as well as to methods of using these molecules and their tau binding fragments in the treatment of alzheimer's disease and tauopathies.. . ... Lund Inc

01/12/17 / #20170008898

Cyclic amines

The present invention is directed to novel cyclic amines which inhibit the p2x7 receptor.. . ... Lund Inc

01/12/17 / #20170008459

Retractable vehicle step

A retractable vehicle step is attachable to a vehicle or truck. The vehicle step facilitates access to a cargo hold, interior, or roof of the vehicle. ... Lund Inc

01/05/17 / #20170001587

Rock guard for highway vehicles

Rock guards can be used to protect parts, such as a radiator, in the engine compartment of highway vehicles. The present disclosure relates to a rock guard that includes a body with self-supporting frameless structure that has a hem and a plurality of mounting points mountable to a structure of the vehicle. ... Lund Inc








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