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Mcgill University patents


Recent patent applications related to Mcgill University. Mcgill University is listed as an Agent/Assignee. Note: Mcgill University may have other listings under different names/spellings. We're not affiliated with Mcgill University, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "M" | Mcgill University-related inventors


Tc-ptp inhibitors as apc activators for immunotherapy

The invention encompasses the novel class of compounds represented by the formula (i) below, which are inhibitors of the tc-ptp enzyme. The invention also encompasses pharmaceutical compositions which include the compounds shown above and methods of treating or preventing tc-ptp mediated diseases, including cancer, via their use in the activation of antigen-presenting cells, like dendritic cells, for applications in the immunotherapeutic treatment of diseases.. ... Mcgill University

Markers to predict macrocyclic lactone drug resistance in dirofilaria immitis, the causative agent of heartworm disease

Disclosed are nucleic acid molecules from the genome of dirofilaria spp. Nematodes that contain single nucleotide polymorphisms related to reduced responsiveness of the nematodes to macrocyclic lactones. ... Mcgill University

Electrocyclonic particle collector

An electrocyclonic particle collector (epc) for removing particulate matter from a gas includes an epc gas inlet, an epc gas outlet, and an epc gas flow path between the epc gas inlet and the epc gas outlet. A first section is downstream of the epc gas inlet and includes a first cyclonic particle collector in the gas flow path for cyclonically removing particles from the gas. ... Mcgill University

Tc-ptp inhibitors as apc activators for immunotherapy

The invention encompasses the novel class of compounds represented by the formula (i) below, which are inhibitors of the tc-ptp enzyme. The invention also encompasses pharmaceutical compositions which include the compounds shown above and methods of treating or preventing tc-ptp mediated diseases, including cancer, via their use in the activation of antigen-presenting cells, like dendritic cells, for applications in the immunotherapeutic treatment of diseases.. ... Mcgill University

Simultaneous segmentation and grading of structures for state determination

Applicants have discovered a new low-cost and accessible method and apparatus that allowing for quicker and more precise state determinations based on medical images. The method and apparatus are non-intrusive and require providing a medical image of a subject and determining a state based on a comparison to a training image set comprising two or more states. ... Mcgill University

Pyrimidines for treatment of bacterial infections

Filamenting temperature-sensitive mutant z (ftsz) protein plays a crucial role in the bacterial cell division machinery and is a validated drug target for antibacterial agents. The present invention relates to ftsz-interacting compounds that possess a 2,4,6-trisubstituted pyrimidine scaffold. ... Mcgill University

Vision strengthening methods and systems

Active dichoptic perceptual-learning tasks or dichoptic game play have been shown to significantly improve visual acuity of amblyopic children and adults. However, these dichoptic perceptual learning tasks are intensive and repetitive such that non-compliance is high. ... Mcgill University

Injectable chitosan sponges for enhancing bone regeneration

It is provided a chitosan sponge for bone regeneration in a subject, comprising chitosan; a purine compound such as guanosine 5′-diphosphate (gdp); and at least one of a growth factor and a pyrophosphatase. Preferably the growth factor is bmp-7. ... Mcgill University

Alkyne-, azide- and triazole-containing flavonoids as modulators for multidrug resistance in cancers

A triazole bridged flavonoid dimer compound library was efficiently constructed via the cycloaddition reaction of a series of flavonoid-containing azides (az 1-15) and alkynes (ac 1-17). These triazole bridged flavonoid dimers and their precursor alkyne- and azide-containing flavonoids were screened for their ability to modulate multidrug resistance (mdr) in p-gp-overexpressed cell line (lcc6mdr), mrp1-overexpressed cell line (2008/mrp1) and bcrp-overexpressed cell line (hek293/r2 and mcf7-mx100). ... Mcgill University

Methods and compositions for treatment of drug addiction

Methods of reducing ampa/nmda ratio in d1-type medium spiny neurons (msn) and/or reducing development of behavioural sensitization or suppressing drug induced behavioural sensitization in a subject, optionally a subject that is afflicted with an addiction, the method comprising administering to the subject in need thereof an effective amount of a toll-like receptor 4 (tlr4) agonist or a composition comprising said tlr4 agonist, preferably wherein the tlr4 agonist is a monophosphoryl lipid a (mpla).. . ... Mcgill University

Tc-ptp inhibitors as apc activators for immunotherapy

The invention encompasses the novel class of compounds represented by the formula (i) below, which are inhibitors of the tc-ptp enzyme. The invention also encompasses pharmaceutical compositions which include the compounds shown above and methods of treating or preventing tc-ptp mediated diseases, including cancer, via their use in the activation of antigen-presenting cells, like dendritic cells, for applications in the immunotherapeutic treatment of diseases.. ... Mcgill University








ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009



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