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Medical Diagnostic Laboratories Llc patents


Recent patent applications related to Medical Diagnostic Laboratories Llc. Medical Diagnostic Laboratories Llc is listed as an Agent/Assignee. Note: Medical Diagnostic Laboratories Llc may have other listings under different names/spellings. We're not affiliated with Medical Diagnostic Laboratories Llc, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "M" | Medical Diagnostic Laboratories Llc-related inventors


Novel cell based assay

The present invention relates to cell-based assays involving her2. The assays use assay cells that are transfected with cassettes containing the her2 gene of interest and measure the effect of mutations on the activity of her2, and on their response to inhibitors.. ... Medical Diagnostic Laboratories Llc

Novel cell based assay

The present invention relates to cell-based assays involving the estrogen receptor and/or aromatase. The assays use assay cells that are transfected with linear cassettes containing the esr1 or the cyp19a1 gene of interest and measure the effect of mutations on the activity of the estrogen receptor and/or aromatase, and on their response to inhibitors.. ... Medical Diagnostic Laboratories Llc

Novel cell-based assay for determining mtor activity

Disclosed are methods of determining activity of mtor variants upon exposure to mtor inhibitors, such a rapamycin or rapalogs thereof, methods for determining kinase activity of a mtor variant, and methods for determining tumor cell response to treatment with rapamycin or rapalogs thereof. A method for determining whether a compound inhibits mtor activity in a cell is also disclosed.. ... Medical Diagnostic Laboratories Llc

Elisa detection of urine dek to predict and diagnose bladder cancer in humans

The present invention is directed to a method of detecting a dek protein in a human urine sample using an elisa assay. Methods and compositions for detection of dek using mab 260-6f9f6 (as detection antibody) and mab 16-2c9c3 (as capture antibody) in human urine are provided herein. ... Medical Diagnostic Laboratories Llc

Method of enhancing mir-185 expression to reduce low density lipoprotein/cholesterol accumulation in a cell

The present invention provides a method of quantifying mir-185 as a potential biomarker in lipid disorder or cardiovascular diseases in human. The present invention also provides a method of modulating mir-185 in regulating ldl and cholesterol metabolism in cells. ... Medical Diagnostic Laboratories Llc

Novel repressor on ifn-lambda promoter and sirna against gata1, evi1, and crx to alter ifn-lambda gene activity

The present invention is directed to the identification of a novel repressor located between ˜1.2 kb to ˜1.6 kb from the translation start site of the ifn-λ1 promoter. The present invention provides a method of using sirnas against zeb1 (binds to the repressor region) and blimp-1 (binds outside the repressor region) and increases the promoter activity of ifn-λ1 (i.e., increases the production of ifn-λ1 protein). ... Medical Diagnostic Laboratories Llc

Pme-1 as a biomarker to predict and diagnose an increased risk of endometrial cancer and gene silencing of pme-1 to inhibit epithelial to mesenchymal transition

Disclosed are methods of attenuating activity of the pme-1 gene. Sirnas or shrnas are used to target against pme-1, thereby reducing the pme-1 mrna. ... Medical Diagnostic Laboratories Llc

Method of receiving and handling a plurality of clinical samples for reporting a sum of diagnostic results for each sample

A method is provided for receiving and handling a plurality of clinical samples and managing information associated therewith for generating and reporting any of a plurality of different diagnostic results from each sample in a timely manner, particularly within about thirty (30) hours. Methods described comprise, for example, receiving a plurality of single gynecological swab samples, each having identity and test requisition information associated therewith, wherein the test requisition information indicates a test for at least one causative agent, from a choice of a plurality of agents (for example, between about 5 and about 25 different microbiological agents) and managing information associated therewith for generating and reporting any of a plurality of different diagnostic results for each sample.. ... Medical Diagnostic Laboratories Llc

Elisa for a naturally-occurring soluble truncated form of il-23 receptor

A naturally-occurring soluble truncated il-23rα protein (i.e., Δ9 il-23rα) is shown to be present in a biological sample and can serve as a diagnostic tool for autoimmune diseases. There is provided an enzyme-linked immunosorbent assay (elisa) and test kit for the serological detection of the soluble truncated form of il-23rα protein. ... Medical Diagnostic Laboratories Llc

Methods and reagents that specifically detect, distinguish and quantify ifn-lambda2 mrna from ifn-lambda3 mrna in humans

The present invention provides a method of specifically detecting ifn-λ2 mrna or ifn-λ3 mrna. There is provided a qrt-pcr method specifically detecting, discriminating and quantifying ifn-λ2 and ifn-λ3 mrna in a biological sample obtained from a human. ... Medical Diagnostic Laboratories Llc








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