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Merck Patent Gmbh patents


Recent patent applications related to Merck Patent Gmbh. Merck Patent Gmbh is listed as an Agent/Assignee. Note: Merck Patent Gmbh may have other listings under different names/spellings. We're not affiliated with Merck Patent Gmbh, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "M" | Merck Patent Gmbh-related inventors


Laser-markable and laser-weldable polymeric materials

. . The present invention relates to coloured laser-markable and laser-weldable polymeric materials which are distinguished by the fact that they comprise, as absorber, at least one doped tin oxide or indium oxide having a large specific surface area.. . ... Merck Patent Gmbh

Amine derivatives as potassium channel blockers

The present invention relates to compounds useful in the modulation of potassium channel activity in cells, in particular the activity of kv1.3 channels found in t cells. The invention also relates to the use of these compounds in the treatment or prevention of autoimmune and inflammatory diseases, including multiple sclerosis, pharmaceutical compositions containing these compounds and methods for their preparation.. ... Merck Patent Gmbh

Perfluoroalkyl group-containing bismuth compounds as lewis acid catalysts

The invention relates to perfluoroalkyl group-containing bismuth compounds as lewis acid catalysts, to specific compounds, and to the method for the production thereof.. . ... Merck Patent Gmbh

Triphenylene-based materials for organic electroluminescent devices

. . . . . . The present invention relates to compounds of the formula (1) and (2) which are suitable for use in electro¬nic devices, in particular organic electroluminescent devices.. . ... Merck Patent Gmbh

Electronic device

The present application relates to an organic electroluminescent device (oled) comprising an emitting layer, where the emitting layer includes a compound having a small difference between the energies of the s1 and t1 states, and further comprising a layer which has been applied from solution between the emitting layer and anode and comprises an amine compound. The present application further relates to a process for producing such an oled.. ... Merck Patent Gmbh

Materials for organic electroluminescent devices

The present invention relates to compounds suitable for use in electronic devices, and to electronic devices, especially organic electroluminescent devices, comprising these compounds.. . ... Merck Patent Gmbh

Compounds for electronic devices

The invention relates to arylamino compounds and to the use thereof in electronic devices, for example organic electroluminescent devices. The invention furthermore relates to electronic devices comprising one or more of the said compounds, for example as hole-transport materials in a corresponding functional layer of the device. ... Merck Patent Gmbh

Compounds for electronic devices

The invention relates to arylamino compounds and to the use thereof in electronic devices, for example organic electroluminescent devices. The invention furthermore relates to electronic devices comprising one or more of the said compounds, for example as hole-transport materials in a corresponding functional layer of the device. ... Merck Patent Gmbh

Pigment powders

Disclosed are pigment powders containing only coated biocl flakes, which flakes area) biocl flakes having a coating containing yellow iron oxide fe2o3*xh2o, optionally a colorant, optionally an adjuvant, and optionally sio2, b) biocl flakes having a coating containing sio2, optionally a colorant, and optionally an adjuvant, c) biocl flakes having a coating containing a colorant, sio2, optionally yellow iron oxide fe2o3*xh2o, and optionally an adjuvant, or d) biocl flakes having a coating containing fe3o4 and optionally sio2, to a process for the preparation of the pigment powders, and to the use thereof especially in cosmetic formulations.. . ... Merck Patent Gmbh

Metal complexes

. . The present invention relates to metal complexes and to electronic devices, especially organic electroluminescent devices, comprising these metal complexes.. . ... Merck Patent Gmbh

Methods for the modulation of lgals3bp to treat systemic lupus erythematosus

Embodiments of the present invention describe methods for modulating lgals3bp and the use of antibodies to the same in the treatment of autoimmune diseases including systemic lupus erythematosus and lupus nephritis.. . ... Merck Patent Gmbh

Tablets having media independent active substance delivery

The present invention relates to formulations having extended release of active ingredient, comprising an active ingredient from bcs class i having high solubility and high permeability in a polyvinyl alcohol-containing matrix, from which the active ingredient is released at a controlled rate over a therapeutically relevant time period independently of the composition of the release medium.. . ... Merck Patent Gmbh

Materials for electronic devices

. . The present application relates to compounds of a formula (i), to the use thereof in organic electroluminescent devices, and to processes for preparing these compounds.. . ... Merck Patent Gmbh

Phenoxazine derivatives for organic electroluminescent devices

The present invention relates to the compounds of the formulae (1) and (2) and to organic electroluminescent devices, in particular blue-emitting devices, in which these compounds are used as host material or dopant in the emitting layer and/or as hole-transport material and/or as electron-transport material.. . ... Merck Patent Gmbh

08/23/18 / #20180240979

Materials for electronic devices

The present application relates to a compound of a formula (i) which contains a spirobifluorene basic structure condensed onto a benzofuran unit. The application furthermore relates to a process for the preparation of the compound of the formula (i), and to the use of the compound of the formula (i) in an electronic device.. ... Merck Patent Gmbh

08/23/18 / #20180237696

Material combination

The invention relates to a material combination comprising a first fluid comprising a liquid crystal material, and an electrically insulating second fluid substantially not miscible with the first fluid, and to an optical device using the same.. . ... Merck Patent Gmbh

08/23/18 / #20180237426

Heteroaryl compounds as irak inhibitors and uses thereof

The present invention relates to compounds of formula i and pharmaceutically acceptable compositions thereof, useful as irak inhibitors.. . ... Merck Patent Gmbh

08/23/18 / #20180237413

Heteroaryl compounds as irak inhibitors and uses thereof

The present invention relates to compounds of formula i and pharmaceutically acceptable compositions thereof, useful as irak inhibitors.. . ... Merck Patent Gmbh

08/23/18 / #20180237410

Hydrophilic compounds for optically active devices

The present invention relates to novel compounds, particularly to hydrophilic compounds, comprising a photoactive unit, said novel compounds being particularly suitable for ophthalmic devices. The present application also relates to ophthalmic devices comprising such compounds.. ... Merck Patent Gmbh

08/23/18 / #20180237409

Compounds for optically active devices

The present invention relates to novel compounds, particularly to compounds comprising a photoactive unit, said novel compounds being particularly suitable for ophthalmic devices as well as to ophthalmic devices comprising such compounds.. . ... Merck Patent Gmbh

08/23/18 / #20180236032

Combination composition comprising fgf-18 compound

The present invention relates to the use of an fgf-18 compound in combination with a further active ingredient, selected from the group of an inhibitor of il-6, an inhibitor of il-6 receptor, an inhibitor of ngf or a botulinum toxin compound. Said composition can be used for the treatment of a cartilage disorder such as osteoarthritis or cartilage injury.. ... Merck Patent Gmbh

08/16/18 / #20180230449

Artificial non-ribosomal peptide synthetases

. . The present invention concerns a novel method for the modification and/or custom-made design of artificial non-ribosomal peptide synthetases (nrpss) from naturally available nrpss. The artificial nrpss are of predetermined length and amino acid composition and sequence. ... Merck Patent Gmbh

08/16/18 / #20180230422

Cell culture media

The present invention relates to cell culture media comprising inorganic ester derivatives of tyrosine and/or cysteine. The poor solubility of tyrosine and the often non-sufficient stability of cysteine in cell culture media is overcome by substituting them with an inorganic ester derivative, e.g. ... Merck Patent Gmbh

08/16/18 / #20180230382

Liquid-crystalline media

Liquid-crystalline media which can be used, in particular, for electro-optical displays having active-matrix addressing based on the ecb effect and for ips (in-plane switching) displays or ffs (fringe field switching) displays.. . ... Merck Patent Gmbh

08/16/18 / #20180230378

Materials for organic electroluminescent devices

The present invention relates to mixtures comprising at least one phosphorescent dopant and at least one compound of one of the formulae (1) and (2), and the use thereof in electronic devices, especially in organic electroluminescent devices.. . ... Merck Patent Gmbh

08/16/18 / #20180230375

Formulation of an organic functional material comprising an epoxy group containing solvent

The present invention relates to formulations containing at least one organic functional material and at least a first organic solvent, wherein said first organic solvent contains at least one epoxy-group as well as to electronic devices prepared by using these formulations.. . ... Merck Patent Gmbh

08/16/18 / #20180230162

Compounds for the inhibition of cyclophilins and uses thereof

The present invention relates to compounds, and pharmaceutically acceptable compositions thereof, useful as inhibitors of cyclophilins, and for the treatment of cyclophilin-related disorders.. . ... Merck Patent Gmbh

08/09/18 / #20180226591

Electroluminescent bridged metal complexes for use in electronic devices

. . The present invention relates to metal complexes and to electronic devices, especially organic electroluminescent devices, comprising these metal complexes.. . ... Merck Patent Gmbh

08/09/18 / #20180226587

Compounds having fluorene structures

The present invention describes fluorene derivatives substituted by electron-transporting groups, especially for use as triplet matrix materials in electronic devices. The invention further relates to a process for preparing the compounds of the invention and to electronic devices comprising these.. ... Merck Patent Gmbh

08/09/18 / #20180226586

Phenyl derivatives substituted with at least two electron acceptors and at least two electron donors for use in organic electronic devices

The present invention relates to a phenyl-derivative compound substituted with at least two electron acceptors and at least two electron donors. Formula (i) raardbrscc6 wherein a is 2, 3 or 4; b is 2, 3 or 4; c is 0, 1 or 2; a+b−c=6; ra is at each occurrence independently a group with −m-effect; rb is at each occurrence independently a group with +−m-effect; rs is as defined in claim 1. ... Merck Patent Gmbh

08/09/18 / #20180223250

Process for producing cell culture media

The present invention relates to a process for manufacturing dry powder cell culture media. The preparation and usage of mixed particles generated by co-lyophilisation leads to cell culture media with improved solubility without changing the chemical composition.. ... Merck Patent Gmbh

08/09/18 / #20180223189

Liquid crystal medium and liquid crystal display

The present invention relates to mesogenic media and to electro-optical displays comprising these media as light modulation media. In particular, the electro-optical displays according to the present invention are displays, which are operated at a temperature, at which the mesogenic modulation media are in an optically isotropic phase, preferably in a blue phase.. ... Merck Patent Gmbh

08/09/18 / #20180223115

Laser-markable polymers and coatings

The present invention relates to laser-markable polymers and coatings which are distinguished by the fact that they comprise tin/antimony oxide-coated spherical tio2 particles of defined particle size as laser additive.. . ... Merck Patent Gmbh

08/09/18 / #20180223103

Colouring of surfaces

The present invention relates to a process for colouring surfaces, in particular surfaces of foods, with effect pigments, preferably pearlescent pigments, based on flake-form substrates, where (i) the effect pigment is incorporated into a pasty, transparent, water-based material and (ii) the application medium prepared in step (i) is applied to the surface.. . ... Merck Patent Gmbh

08/09/18 / #20180222872

Materials for organic electroluminescent devices

Fluorene derivatives that are connected in one or more of the 1-, 1′-, 4-, or 4′-positions in any combination to a carbon atom of a diaryl substituted triazinyl or pyrimidinyl derivative. The fluorene derivatives are not spirobifluorene derivatives. ... Merck Patent Gmbh

08/09/18 / #20180220685

Preparation and colouring of pulverulent foods

A process for the preparation and colouring of pulverulent foods which is distinguished by the fact that uncoloured pulverulent foods are mixed with effect pigments based on flake-form substrates.. . ... Merck Patent Gmbh

08/02/18 / #20180219156

Materials for organic electroluminescent devices

. . . . The present invention relates to compounds of the formula (1) which are suitable for use in electronic devices, in particular organic electroluminescent devices, and to electronic devices which comprise these compounds.. . ... Merck Patent Gmbh

08/02/18 / #20180216061

Method for increasing the glutathione level in cells

The present invention relates to the use of sulfocysteine and derivatives thereof to increase the gluthathione pool in cells.. . ... Merck Patent Gmbh

08/02/18 / #20180215998

Luminescent particle, ink formulation, polymer composition, optical device, fabrication of thereof, and use of the luminescent particle

The present invention relates to a luminescent particle, ink formulation, polymer composition, optical device and a preparation thereof. The invention further relates to use of a luminescent particle in a medium or biological imaging.. ... Merck Patent Gmbh

08/02/18 / #20180215786

Removal of protein aggregates from biopharmaceutical preparations in a flow-through mode

The present invention provides novel compositions and methods for removal of protein aggregates from a sample in a flow-through mode.. . ... Merck Patent Gmbh

07/26/18 / #20180212166

Composition comprising organic semiconducting compounds

The present invention relates to novel composition comprising an organic semiconductor (osc) and organic solvents. The composition comprises at least two organic solvents. ... Merck Patent Gmbh

07/26/18 / #20180212149

Materials for organic electroluminescent devices

The present invention relates to compounds of the formula (1) which are suitable for use in electronic devices, in particular organic electroluminescent devices, and to electronic devices which comprise these compounds.. . ... Merck Patent Gmbh

07/26/18 / #20180210272

Device for the regulation of light transmission

The present application concerns a switchable device for the regulation of light transmission, which has a compartemented structure, where the switching state of each of the compartments can be controlled individually.. . ... Merck Patent Gmbh

07/26/18 / #20180208848

Liquid crystalline media having homeotropic alignment

The present invention relates to liquid-crystalline media (lc media) having negative or positive dielectric anisotropy, comprising a low-molecular-weight component and a polymerisable component. The polymerisable component comprises self-aligning, polymerisable mesogens (polymerisable self-alignment additives) which effect homeotropic (vertical) alignment of the lc media at a surface or the cell walls of a liquid-crystal display (lc display). ... Merck Patent Gmbh

07/26/18 / #20180207545

Apparatus for vacuum purification

The present invention relates to a process for the vacuum purification of chemical compounds and to an apparatus for carrying out this process.. . ... Merck Patent Gmbh

07/26/18 / #20180207101

Pulverulent, directly compressible polyvinyl alcohol grades

The present invention relates to premixes for the production of active compound-containing tablets which comprise polyvinyl alcohols (pvas). The invention also relates to active compound-containing tablets which comprise a corresponding premix.. ... Merck Patent Gmbh

07/26/18 / #20180207080

Compositions of fluorinated surfactants and antioxidants

The invention relates to the use of specific fluorosurfactants for increasing the efficacy of antioxidants, in particular in cosmetic, dermatological preparations and medicinal products, and to specific mixtures and preparations. . ... Merck Patent Gmbh

07/19/18 / #20180201837

Method of reducing odf mura in polymer stabilised liquid crystal displays

The present invention relates to a method of reducing odf mura in liquid crystal (lc) displays of the polymer sustained alignment (psa) type and to psa lc displays made by this method.. . ... Merck Patent Gmbh

07/12/18 / #20180198068

Organic semiconducting compounds

. . . . . . The invention relates to novel organic semiconducting compounds containing a polycyclic unit, to methods for their preparation and educts or intermediates used therein, to compositions, polymer blends and formulations containing them, to the use of the compounds, compositions and polymer blends as organic semiconductors in, or for the preparation of, organic electronic (oe) devices, especially organic photovoltaic (opv) devices, perovskite-based solar cell (psc) devices, organic photodetectors (opd), organic field effect transistors (ofet) and organic light emitting diodes (oled), and to oe, opv, psc, opd, ofet and oled devices comprising these compounds, compositions or polymer blends.. . ... Merck Patent Gmbh

07/12/18 / #20180197927

Organic electronic devices with fluoropolymer bank structures

An electronic device and methods for its preparation comprising an active area between first and second conductive layers on a substrate; the active area is in a well whose bottom is a patterned first conductive layer on the substrate, the sides of the well are bank structures comprising a non-radiative active fluoropolymer which overlap the edges of the first conductive layer and which are in contact with the substrate. The well contains active materials, preferably introduced by a solution method such as ink-jet. ... Merck Patent Gmbh

07/05/18 / #20180188586

Process of preparing a light modulation element

The present invention relates to a process of preparing a light modulation element of the ps-ulh (polymer stabilised ulh) type.. . ... Merck Patent Gmbh

07/05/18 / #20180187081

Process of preparing a light modulation element

The present invention relates to a process of preparing a light modulation element of the ps-ulh (polymer stabilised ulh) type, which allows to reduce the operational voltage and allows to improve the switching time of the light modulation element.. . ... Merck Patent Gmbh

07/05/18 / #20180187080

Liquid crystal medium containing polymerisable compounds

The present invention relates to a liquid crystal (lc) medium comprising polymerisable compounds, to a process for its preparation, to its use for optical, electro-optical and electronic purposes, in particular in lc displays, and to lc displays comprising it.. . ... Merck Patent Gmbh

06/28/18 / #20180179446

Liquid crystal medium containing polymerisable compounds

The present invention relates to a liquid crystal (lc) medium comprising polymerisable compounds, to a process for its preparation, to its use for optical, electro-optical and electronic purposes, in particular in lc displays, and to lc displays comprising it.. . ... Merck Patent Gmbh

06/28/18 / #20180179232

Boronic acid derivatives

Compounds of formula (i) are inhibitors of lmp7 and can be employed, inter alia, for the treatment of an autoimmune disorder or hematological malignancies.. . ... Merck Patent Gmbh

06/28/18 / #20180179231

Boronic acid derivatives

Compounds of formula (i) are inhibitors of lmp7 and can be employed, inter alia, for the treatment of an autoimmune disorder or hematological malignancies.. . ... Merck Patent Gmbh

06/21/18 / #20180174158

Composite security marking

. . The present disclosure relates to the field of anti-counterfeit protection of products. Specifically, the disclosure is directed to a composite security marking for a physical object, in particular to an anti-counterfeit product marking. ... Merck Patent Gmbh

06/21/18 / #20180174157

Composite security marking

The present invention relates to the field of anti-counterfeit protection of products. Specifically, the invention is directed to a composite security marking for a physical object, in particular to an anti-counterfeit product marking. ... Merck Patent Gmbh

06/21/18 / #20180173917

Reader device for reading a marking comprising a physical unclonable function

The present disclosure relates to the field of anti-counterfeit protection of products. Specifically, the disclosure is directed to a method of reading with a reader device a marking comprising a physical unclonable function, puf, and a corresponding reader device. ... Merck Patent Gmbh

06/21/18 / #20180173916

Reader device for reading a marking comprising a physical unclonable function

The present invention relates to the field of anti-counterfeit protection of products. Specifically, the invention is directed to a method of reading with a reader device a marking comprising a physical unclonable function, puf, and a corresponding reader device. ... Merck Patent Gmbh

06/21/18 / #20180171020

Methods for generating bispecific shark variable antibody domains and use thereof

The present invention provides a method for generating bispecific shark variable antibody domains (vnar domains) and uses thereof. The present invention further provides fusion proteins comprising the inventive bispecific vnar domains as well as polynucleotide libraries for use in the generation of the inventive bi-specific vnars. ... Merck Patent Gmbh

06/21/18 / #20180169094

Pyrimidine pyrazolyl derivatives and their use as irak inhibitors

The present invention provides compounds of formula (ii) for the treatment of cancer, rheumatoid arthritis and other diseases.. . ... Merck Patent Gmbh

06/14/18 / #20180163171

Deep eutectic solvents and/or ionic liquids in cell culture media

. . . . The present invention relates to cell culture media compositions comprising deep eutectic solvents and/or ionic liquids.. . ... Merck Patent Gmbh

06/14/18 / #20180163137

Polymerisable compounds and the use thereof in liquid-crystal displays

Polymerisable compounds, processes and intermediates for the preparation thereof, liquid-crystal (lc) media comprising them, and the use of the polymerisable compounds and lc media for optical, electro-optical and electronic purposes, in particular in lc displays, especially in lc displays of the polymer sustained alignment type.. . ... Merck Patent Gmbh

06/14/18 / #20180163070

Solution process for insb nanoparticles and application for ir detectors

This invention relates to a process for synthesizing insb nanoparticles, a method to stabilize them, and a method to provide a photodetector to detect infrared light.. . ... Merck Patent Gmbh

06/14/18 / #20180162843

Materials for organic electroluminescent devices

The present invention relates to compounds which are suitable for use in electronic devices, and to electronic devices, in particular organic electroluminescent devices, comprising these compounds. The compounds have a dibenzofuran, dibenzothiophene or a fluorene group substituted in the 1-position, either directly or through a linking group, to a carbon atom of a heteroaromatic group with one or two nitrogen atoms in a bicyclic 6/6 core, or to a carbon or nitrogen atom of a heteroaromatic group with two nitrogen atoms in a bicyclic 5/6 core and is further substituted with a group selected from dibenzofuran, dibenzothiophene, fluorene or carbazole.. ... Merck Patent Gmbh

06/14/18 / #20180162817

Compounds for optically active devices

The present invention relates to novel compounds, particularly to compounds comprising a photoactive unit, said novel compounds being particularly suitable for ophthalmic devices as well as to ophthalmic devices comprising such compounds.. . ... Merck Patent Gmbh

06/07/18 / #20180157088

Optical switching layer for use in an optical switching element

. . The present invention presents a switching layer s for use in a switching element which has forwards-scattering properties in at least one switching state. Furthermore, a switching element which comprises the switching layer s and a window element which includes the switching element are presented.. ... Merck Patent Gmbh

06/07/18 / #20180155621

Phosphors and phosphor-converted leds

The present invention relates to pyrosilicate phosphors, to a process for the preparation thereof and to the use thereof as conversion phosphors. The present invention also relates to an emission-converting material comprising the conversion phosphor according to the invention, and to the use thereof in light sources, in particular pc-leds (phosphor converted light emitting devices). ... Merck Patent Gmbh

06/07/18 / #20180155616

Esters containing non-aromatic cycles as solvents for oled formulations

The present invention relates to formulations for the preparation of organic electronic devices (oleds) which comprise at least one specific ester solvent containing a non aromatic cycle and at least one organic functional material selected from organic conductors, organic semiconductors, organic fluorescent compounds, organic phosphorescent compounds, organic light-absorbent compounds, organic light-sensitive compounds, organic photosensitisation agents and other organic photoactive compounds, selected from organometallic complexes of transition metals, rare earths, lanthanides and actinides.. . ... Merck Patent Gmbh

06/07/18 / #20180155339

Method for the production of praziquantel

The present invention relates to a method for the racemization of enantiomerically pure or enantiomerically enriched praziquantel under basic conditions and a method for the production of (r)-praziquantel in enantiopure or enantiomerically enriched form, which comprises the racemization method.. . ... Merck Patent Gmbh

05/31/18 / #20180148648

Reactive mesogens

The invention relates to lateral fluorinated reactive mesogens (rms) comprising a tolane group, to mixtures and formulations comprising them, to polymers obtained form such rms and rm mixtures, and the use of the rms, rm mixtures and polymers in optical or electrooptical components or devices, like optical films for liquid crystal displays (lcds).. . ... Merck Patent Gmbh

05/24/18 / #20180145260

Materials for organic electrluminescent devices

. . The present invention relates to the fluorene derivatives and to organic electronic devices in which these compounds are used as matrix material in the emitting layer and/or as hole transport material and/or as electron blocker or exciton blocker material and/or as electron transport material.. . ... Merck Patent Gmbh

05/24/18 / #20180142152

Compounds for the homeotropic alignment of liquid-crystalline media

Disclosed are liquid-crystalline media (lc media) comprising a low-molecular-weight component and a polymerisable component. The polymerisable component contains self-aligning, polymerisable mesogens (polymerisable self-alignment additives) which effect homeotropic (vertical) alignment of the lc media at a surface or the cell walls of a liquid-crystal display (lc display). ... Merck Patent Gmbh

05/17/18 / #20180138439

Electronic device

. . The present application relates to an electronic device comprising a hole-transport layer a, a doped hole-transport layer b and a hole-transport layer c, where hole-transport layers a, b and c are arranged between the anode and the emitting layer, and where hole-transport layer b is arranged on the cathode side of hole-transport layer a and hole-transport layer c is arranged on the cathode side of hole-transport layer b.. . ... Merck Patent Gmbh

05/17/18 / #20180134959

Liquid-crystal medium

The present invention relates to a liquid crystal (lc) medium comprising a polymerisable compound, to a process for its preparation, to its use for optical, electro-optical and electronic purposes, in particular in lc displays, especially in an lc display of the polymer sustained alignment (psa) type, and to an lc display, especially a psa display, comprising it.. . ... Merck Patent Gmbh

05/17/18 / #20180133334

Targeting aminoacid lipids

The present invention is directed to carrier systems comprising ether-lipids conjugated to one or more bioactive ligands and exposed on the surface of the carrier system for use in targeted delivery and/or antigen display systems. Optionally one or more further bioactive agents may be encapsulated or embedded within or attached to or adsorbed onto the carrier system. ... Merck Patent Gmbh

05/10/18 / #20180126298

Device for substance separation

The invention relates to a device for substance separation with monolithic sorbents which can be produced by means of 3-d printing. They comprise pressure- and solvent-stable thermoplastics.. ... Merck Patent Gmbh

05/03/18 / #20180122974

Wavelength conversion polymer film

. . . . The invention relates to a polymer film comprising an inorganic fluorescent compound and an organic fluorescent compound. The invention further relates methods for preparing such a film, and to its use as wavelength conversion film in a solar cell.. ... Merck Patent Gmbh

05/03/18 / #20180122640

Screen-printable boron doping paste with simultaneous inhibition of phosphorus diffusion in co-diffusion processes

The present invention relates to a novel printable boron doping paste in the form of a hybrid gel based on precursors of inorganic oxides, preferably of silicon dioxide, aluminium oxide and boron oxide, in the presence of organic polymer particles, where the pastes according to the invention can be used in a simplified process for the production of solar cells, where the hybrid gel according to the invention functions both as doping medium and as diffusion barrier.. . ... Merck Patent Gmbh

05/03/18 / #20180118832

Combination therapy for cancer

This invention relates generally to a combination therapy for the treatment of cancer, particularly to a combination of (i) a bifunctional molecule comprising a tgfβrii or fragment thereof capable of binding tgfβ and an antibody, or antigen binding fragment thereof, that binds to an immune checkpoint protein, such as programmed death ligand 1 (pd-l1) and (ii) at least one additional anti-cancer therapeutic agent.. . ... Merck Patent Gmbh

04/19/18 / #20180105637

Thiadiazolopyridine polymers, their synthesis and their use

. . The present invention relates to thiadiazolopyridine polymers, their synthesis and their use. The present invention further relates to organic electronic devices comprising such thiadiazolopyridine polymers.. ... Merck Patent Gmbh

04/19/18 / #20180105539

Boronic acid derivatives

Compounds of formula (i) are inhibitors of lmp7 and can be employed, inter alia, for the treatment of an autoimmune disorder or hematological malignancies.. . ... Merck Patent Gmbh

04/19/18 / #20180105538

Boronic acid derivatives

Compounds of formula (i) are inhibitors of lmp7 and can be employed, inter alia, for the treatment of an autoimmune disorder or hematological malignancies.. . ... Merck Patent Gmbh

04/12/18 / #20180102479

Phenanthrene compounds for organic electronic devices

. . . . The invention relates to specific phenanthrenes, the use of the compound in an electronic device, and an electronic device containing at least one of said compounds. The invention further relates to a method for producing the compound and a formulation and composition containing one or more of the compounds.. ... Merck Patent Gmbh

04/05/18 / #20180097178

Compounds and organic electronic devices

. . The present invention relates to certain fluorenes, to the use of the compounds in an electronic device, and to an electronic device comprising at least one of these compounds. The present invention furthermore relates to a process for the preparation of the compounds and to a formulation and composition comprising one or more of the compounds.. ... Merck Patent Gmbh

03/29/18 / #20180090694

Metal complexes

. . The present invention relates to metal complexes and to electronic devices, in particular organic electroluminescent devices, comprising these metal complexes, in particular as emitters.. . ... Merck Patent Gmbh

03/29/18 / #20180090683

Formulation of an organic functional material comprising a siloxane solvent

The present invention relates to a formulation containing at least one organic functional material and at least a first and a second solvent, characterized in that the first solvent is a siloxane.. . ... Merck Patent Gmbh

03/22/18 / #20180081096

A color conversion film, and optical devices

The present invention relates to a color conversion film and to a use of the color conversion film in an optical device. The color conversion film comprises a red sub color area which comprises nanosized 1st and 2nd red color converting material and a green sub color area which comprises nanosized 1st and 2nd green color converting material. ... Merck Patent Gmbh

03/15/18 / #20180072715

Imidazolonylquinolines and the use thereof as atm kinase inhibitors

. . Compounds of the formula (i), which are atm kinase inhibitors and can be employed, inter alia, for the treatment of cancer.. . ... Merck Patent Gmbh

03/15/18 / #20180071386

Silicon dioxide nanoparticles and the use thereof for vaccination

The invention relates to ultrasmall, monodisperse nanoparticles comprising silicon dioxide to the surface of which at least one antigen is attached. The nanoparticles can be used for the immunoprophylaxis or immunotherapy of cancer. ... Merck Patent Gmbh

03/08/18 / #20180066186

Phosphors and phosphor-converted leds

The present invention relates to alkaline earth aluminate phosphors, to a process for the preparation thereof and to the use thereof as conversion phosphors. The present invention also relates to an emission-converting material comprising at least the conversion phosphor according to the invention, and to the use thereof in light sources, in particular pc-leds (phosphor converted light emitting devices). ... Merck Patent Gmbh

03/08/18 / #20180066000

Metal complexes and electroluminescent devices comprising these metal complexes

The present invention relates to metal complexes having a metal atom of groups 13 to 15 and at least one ligand, where the ligand comprises at least one anionic coordination group having at least one oxygen and/or nitrogen atom via which the metal atom is coordinated, and the ligand comprises at least one triarylamine group, to processes for preparation thereof and to the use thereof in electronic devices, especially in organic electroluminescent devices, called oleds (oled=organic light emitting diode). The present invention also further relates to organic electroluminescent devices comprising these metal complexes.. ... Merck Patent Gmbh

03/01/18 / #20180062022

Sol-gel-based printable doping media which inhibit parasitic diffusion for the local doping of silicon wafers

The present invention relates to a novel printable paste in the form of a hybrid gel based on precursors of inorganic oxides which can be used in a simplified process for the production of solar cells, where the hybrid gel according to the invention functions both as doping medium and also as diffusion barrier.. . ... Merck Patent Gmbh

03/01/18 / #20180057743

Liquid-crystalline media having homeotropic alignment

The present invention relates to liquid-crystalline media (lc media) having negative or positive dielectric anisotropy, comprising a low-molecular-weight component and a polymerizable component. The polymerizable component comprises self-aligning, polymerizable mesogens (polymerizable self-alignment additives) which effect homeotropic (vertical) alignment of the lc media at a surface or the cell walls of a liquid-crystal display (lc display). ... Merck Patent Gmbh

02/22/18 / #20180053873

Process for the production of solar cells using printable doping media which inhibit the diffusion of phosphorus

The present invention relates to a novel printable medium in the form of a hybrid sol and/or gel based on precursors of inorganic oxides for use in a simplified process for the production of solar cells, in which the medium according to the invention functions both as doping medium and also as diffusion barrier.. . ... Merck Patent Gmbh

02/22/18 / #20180051206

Materials for organic electroluminescent devices

The present invention relates to a compound of formula (i) or (ii), which is suitable for use as functional material in an electronic device, in particular as emitter material in an organic electroluminescent device.. . ... Merck Patent Gmbh

02/22/18 / #20180051024

2-oxo-imidazopyridines as reversible btk inhibitors and uses thereof

The present invention relates to imidazo pyridine compounds, and pharmaceutically acceptable compositions thereof, useful as btk inhibitors.. . ... Merck Patent Gmbh

02/15/18 / #20180044591

Liquid-crystal medium

The present invention relates to a liquid crystal (lc) medium comprising a polymerizable compound, to a process for its preparation, to its use for optical, electro-optical and electronic purposes, in particular in lc displays, especially in an lc display of the polymer sustained alignment (psa) type, and to an lc display, especially a psa display, comprising it.. . ... Merck Patent Gmbh

02/08/18 / #20180040832

Electronic device containing cyclic lactams

The present invention relates to electronic devices containing special cyclic lactams, more particularly organic electroluminescent devices, and to special cyclic lactams for use in electronic devices, more particularly in organic electroluminescent devices.. . ... Merck Patent Gmbh

02/08/18 / #20180037820

Piperidine derivatives and liquid-crystalline medium

Disclosed are compounds of the formula i, liquid-crystalline media comprising the compounds of formula i, and the use of these liquid-crystalline media in liquid-crystal displays.. . ... Merck Patent Gmbh

02/08/18 / #20180037744

Particles for electrophoretic displays

This invention relates to polymer particles preferably with surface functionality for charge retention, a process for their preparation, the use of these particles for the preparation of an electrophoretic device, electrophoretic displays comprising such particle, and new polymerisable dyes.. . ... Merck Patent Gmbh

02/08/18 / #20180037743

Particles for electrophoretic displays

This invention relates to polymer particles, a process for their preparation, the use of these particles for the preparation of an electrophoretic device, and electrophoretic displays comprising such particles.. . ... Merck Patent Gmbh

02/08/18 / #20180037570

Tlr7/8 antagonists and uses thereof

The present invention relates to compounds of formula i and pharmaceutically acceptable compositions thereof, useful as tlr7/8 antagonists.. . ... Merck Patent Gmbh

02/01/18 / #20180031941

Multi-electrode total internal reflection image display

. . . . Conventional total internal reflection image displays consist of mobile particles of a single charge and capable of displaying information consisting of two different optical states. The reflective image display embodiments described herein comprises particles of different charge states and optical characteristics in combination with multi-electrode arrays. ... Merck Patent Gmbh

01/25/18 / #20180026209

Metal complexes

. . . . The present invention relates to metal complexes and to electronic devices, especially organic electroluminescent devices, comprising these metal complexes, especially as emitters.. . ... Merck Patent Gmbh

01/25/18 / #20180026188

Spirobifluorene derivative-based materials for electronic devices

The present application relates to spirobifluorene derivatives of a formula (i), to the use thereof in electronic devices, and to processes for preparing said derivatives.. . ... Merck Patent Gmbh

01/25/18 / #20180024404

Electro-optical switching element and display device

The present invention relates to an electro-optical switching element comprising at least one light source, and a light converting layer, and to a use of the electro-optical switching element in an optical device. The invention further relates to an optical device comprising the electro-optical switching element.. ... Merck Patent Gmbh

01/25/18 / #20180022997

Liquid crystal displays and liquid crystalline media with homeotropic alignment

The present invention relates to liquid-crystalline media (lc media) having negative or positive dielectric anisotropy comprising self-aligning mesogens (sams) which effect homeotropic (vertical) alignment of the lc media at a surface or the cell walls of a liquid-crystal display (lc display). The invention therefore also encompasses lc displays having homeotropic alignment of the liquid-crystalline medium (lc medium) without conventional imide alignment layers. ... Merck Patent Gmbh

01/25/18 / #20180021730

Connecting mechanism for a water purification cartridge

A connecting mechanism (1) for a cartridge-type replaceable module (2) that has at least one fluid port (2a, 2b) at each of opposite sides of the module (2) in a longitudinal direction of the module (2). The connecting mechanism (1) comprises two connector elements (3) spaced apart in the longitudinal direction of the module (2) and each provided with at least one fluid connector (3b) configured to releasably inter-engage with a complementary fluid port (2a, 2b) of the module (2) at the respective side thereof, wherein at least one of the connector elements (3) is movable to perform a translational movement in the longitudinal direction of the module (2). ... Merck Patent Gmbh

01/25/18 / #20180020661

Powder formulation containing insect repellent

The present invention relates to a powder formulation comprising at least one insect repellent and magnesium hydroxide carbonate, and to a process for the preparation of the formulation and to the use of the formulation for repelling insects.. . ... Merck Patent Gmbh

01/18/18 / #20180019405

Materials for organic electroluminescent devices

The present invention relates to compounds of the formula (1) which are suitable for use in electronic devices, in particular organic electroluminescent devices, and to electronic devices which comprise these compounds.. . ... Merck Patent Gmbh

01/18/18 / #20180016499

Light modulation element

The invention relates to a light modulation element comprising a cholesteric liquid crystalline medium sandwiched between two substrates (1), provided with a common electrode structure (2) and a driving electrode structure (3) individually, wherein the substrate with driving and/or common electrode structure is additionally provided with an alignment electrode structure (4) which is separated from the driving and or common electrode structure on the same substrate by a dielectric layer (5). The invention is further related to a method of production of said light modulation element and to the use of said light modulation element in various types of optical and electro-optical devices, such as electro-optical displays, liquid crystal displays (lcds), non-linear optic (nlo) devices, and optical information storage devices.. ... Merck Patent Gmbh

01/18/18 / #20180016452

Process for printing multicoloured printed images

The present invention relates to a process for printing multicoloured printed images in which exclusively interference pigments are used for the coloured pigmentation of the printing inks, to printed products produced using a process of this type, to the use thereof, and to suitable interference pigments.. . ... Merck Patent Gmbh

01/18/18 / #20180016354

Domain-exchanged antibody

The invention provides for a domain-exchanged antibody comprising a light chain (lc) composed of vl-ch3, and a heavy chain (hc) comprising vh-ch3-ch2-ch3, wherein the vl-ch3 of the lc is dimerising with the vh-ch3 of the hc thereby forming a domain-exchanged lc/hc dimer comprising a ch3lc/ch3hc domain pair, and means and method for producing the same.. . ... Merck Patent Gmbh

01/18/18 / #20180015173

Conjugates for protection from nephrotoxic active substances

The present invention relates to a conjugate containing at least one kidney-selective carrier molecule and at least one active compound which has a protective action for the kidney against nephrotoxic active compounds, to a process for the preparation of the conjugate, to the use thereof for the protection of the kidney against nephrotoxic active compounds, and to a medicament comprising the conjugate.. . ... Merck Patent Gmbh

01/11/18 / #20180013068

Materias for electronic devices

The present invention relates to a compound of the formula (i), (ii) or (iii), to the use of the compound in an electronic device, and to an electronic device comprising a compound of the formula (i), (ii) or (iii). The present invention furthermore relates to a process for the preparation of a compound of the formula (i), (ii) or (iii) and to a formulation comprising one or more compounds of the formula (i), (ii) or (iii).. ... Merck Patent Gmbh

01/11/18 / #20180011359

Device for the regulation of light transmission

The present application discloses a switchable device, comprising a switching layer and a first conductive layer and a second conductive layer, where the switching layer is positioned between the first and the second conductive layer, and where at least one of the first and the second conductive layers comprises a plurality of isolating sections and a plurality of conductive sections, where the isolating sections and the conductive sections alternate over the area of the conductive layer, and where the switching state of the switchable device is controlled by touch motions.. . ... Merck Patent Gmbh

01/11/18 / #20180010046

Polymerisable compounds and the use thereof in liquid-crystal displays

The present invention relates to polymerisable compounds, to processes and intermediates for the preparation thereof, to liquid-crystal (lc) media comprising them, and to the use of the polymerisable compounds and lc media for optical, electro-optical and electronic purposes, in particular in lc displays, especially in lc displays of the polymer sustained alignment type.. . ... Merck Patent Gmbh

01/04/18 / #20180006245

Materials for electronic devices

. . . . The present application relates to spirobifluorene derivatives of a formula (i), to the use thereof in electronic devices, and to processes for preparing said derivatives.. . ... Merck Patent Gmbh

01/04/18 / #20180006237

Materials for electronic devices

The present application relates to a compound which contains an indenocarbazole group, a particular arylamino group and an electron-deficient group bonded to the indenocarbazole group. The compound is suitable for use in electronic devices, in particular in organic electroluminescent devices.. ... Merck Patent Gmbh

01/04/18 / #20180004045

Light modulation element

The invention relates to a light modulation element comprising a cholesteric liquid crystalline medium sandwiched between two substrates (1), provided with a common electrode structure (2) and a driving electrode structure (3) individually, wherein the substrate with driving and/or common electrode structure is additionally provided with an alignment electrode structure (4) which is separated from the driving and or common electrode structure on the same substrate by a dielectric layer (5), characterized in that it comprises at least one alignment layer (6) directly adjacent to the liquid crystalline medium. The invention is further related to a method of production of said light modulation element and to the use of said light modulation element in various types of optical and electro-optical devices, such as electro-optical displays, liquid crystal displays (lcds), non-linear optic (nlo) devices, and optical information storage devices.. ... Merck Patent Gmbh

01/04/18 / #20180002604

Liquid-crystalline medium

The invention relates to a liquid-crystalline medium based on a mixture of polar compounds comprising a self-alignment additive for vertical alignment and additionally at least one compound of formula i as described more closely within this disclosure (polymerizable hals), especially for vertically aligned display applications.. . ... Merck Patent Gmbh

01/04/18 / #20180002436

Targeted tgfß inhibition

This invention relates generally to bifunctional molecules including (a) a tgfβrii or fragment thereof capable of binding tgfβ and (b) an antibody, or antigen binding fragment thereof, that binds to an immune checkpoint protein, such as programmed death ligand 1 (pd-l1), uses of such molecules (e.g., for treating cancer), and methods of making such molecules.. . ... Merck Patent Gmbh

01/04/18 / #20180002387

Variants of group 5 allergens of the true grasses having reduced allergeneity due to mutagenesis of proline residues

The present invention relates to the preparation and use of recombinant variants of group 5 allergens of the poaceae (true grasses), which are characterised by reduced ige reactivity compared with known wild-type allergens and at the same time substantially retained reactivity with t-lymphocytes.. . ... Merck Patent Gmbh

01/04/18 / #20180002327

Heteroaryl compounds as irak inhibitors and uses thereof

The present invention relates to compounds of formula i and pharmaceutically acceptable compositions thereof, useful as irak inhibitors.. . ... Merck Patent Gmbh

12/28/17 / #20170372903

Method for doping semiconductors

. . . . The present invention relates to a process for the production of structured, highly efficient solar cells and of photovoltaic elements which have regions of different doping. The invention likewise relates to the solar cells having increased efficiency produced in this way.. ... Merck Patent Gmbh

12/28/17 / #20170371186

Optical switching device

An optical switching device comprising a polarisation layer and a switching layer which comprises a liquid-crystalline material and a dye compound. Use of the optical switching device for the regulation of the passage of light through an area element. ... Merck Patent Gmbh

12/28/17 / #20170369781

Liquid crystalline medium

The present invention relates to a liquid-crystalline medium based on a mixture of polar compounds having negative dielectric anisotropy (Δε), which is distinguished by the fact that it has a value for the ratio γ1/Δn2 in the range 6-45 with a clearing point of >60° c. And a Δε of ≦−2.3. ... Merck Patent Gmbh

12/28/17 / #20170369773

Organic compounds with soluble groups

The present invention relates to soluble organic compounds, to compositions comprising these compounds, to formulations comprising the compounds or compositions, and to electronic devices.. . ... Merck Patent Gmbh

12/21/17 / #20170365786

Compositions comprising at least one polymer and at least one metal complex and to electroluminescent devices containing said compositions

. . The present invention relates to compositions comprising at least one polymer which contains triarylamine repeating units, and at least one metal complex, to methods for the production thereof, and the use thereof in electronic devices, especially in organic electroluminescent devices, so-called oleds (oled=organic light emitting diode). The present invention also relates to organic electroluminescent devices which contain said compositions. ... Merck Patent Gmbh

12/21/17 / #20170365785

Compositions comprising at least one polymer and at least one salt, and electroluminescent devices containing said compositions

The present invention relates to compositions comprising at least one polymer containing repeat triarylamine units and comprising at least one salt, to processes for production thereof and to the use thereof in electronic devices, especially in organic electroluminescent devices, called oleds (oled=organic light-emitting diodes). The present invention also further relates to organic electroluminescent devices comprising these compositions.. ... Merck Patent Gmbh

12/21/17 / #20170365734

Laser doping of semiconductors

The present invention relates to a process for the production of structured, highly efficient solar cells and of photovoltaic elements which have regions of different doping. The invention likewise relates to the solar cells having increased efficiency produced in this way.. ... Merck Patent Gmbh

12/21/17 / #20170362505

Compounds having a c-c triple bond

Compounds containing at least one c—c triple bond within a chain of at least 3 ring systems which have positive dielectric anisotropy, the use thereof for high-frequency components, liquid-crystalline media containing these compounds, and high-frequency components, in particular antennae, especially for the gigahertz region, containing these media. The liquid-crystalline media serve, for example, for the phase shifting of microwaves for tuneable phased-array antennae.. ... Merck Patent Gmbh

12/14/17 / #20170358760

Organic electroluminescent device

. . The present invention relates to organic electroluminescent devices which comprise mixtures of at least one phosphorescent material and at least two electron-transporting materials.. . ... Merck Patent Gmbh

12/14/17 / #20170355703

Compounds for the inhibition of indoleamine-2,3-dioxygenase

The present invention relates to compounds, and pharmaceutically acceptable compositions thereof, useful as antagonists of ido, and for the treatment of ido-related disorders.. . ... Merck Patent Gmbh

12/14/17 / #20170355210

Laser-markable and laser-weldable polymeric materials

The present invention relates to laser-markable and laser-weldable polymeric materials which are distinguished by the fact that they comprise, as laser absorber, at least one copper-doped zinc sulfide.. . ... Merck Patent Gmbh

12/07/17 / #20170351130

Light modulation element

. . The invention relates to a light modulation element, preferably exploiting the flexoelectric effect comprising a cholesteric liquid crystalline medium sandwiched between two substrates (1), each provided with an electrode structure (2), wherein at least one of the substrates is provided with a photoresist pattern consisting of periodic substantially parallel stripes (3) which is additionally provided with an alignment layer (4). The invention is further related to a method of production of said light modulation element and to the use of said light modulation element in various types of optical and electro-optical devices, such as electro-optical displays, liquid crystal displays (lcds), non-linear optic (nlo) devices, and optical information storage devices.. ... Merck Patent Gmbh

12/07/17 / #20170350753

Spectrophotometer and method for carrying out a spectrophotometric measurement

The present invention relates to a spectrophotometer comprising a light source; and a light sensor for measuring the light emitted by the light source and passing through or reflected a sample; and being characterized by an offset generator for applying an offset value to an output of the light sensor. The invention further relates to a method for performing a related spectrophotometric measurement.. ... Merck Patent Gmbh

12/07/17 / #20170349761

Fluorine compounds

The present invention relates to compounds of the formula (i) (rf—chf—cf2—chr)m-l-(x)n, where rf=a perfluorinated alkyl group, optionally containing heteroatoms, r=h or an alkyl group, l=a single bond or a divalent organic group, x=an anchor group, m is ≧1 and n is ≧1, and to the use thereof in, for example, dirt-repellent coatings.. . ... Merck Patent Gmbh

12/07/17 / #20170349760

Fluorine compounds

The present invention relates to novel compounds containing fluorinated end groups and to the use thereof in, for example, dirt-repellent coatings.. . ... Merck Patent Gmbh

12/07/17 / #20170349001

Process for the production of a pattern having a three-dimensional appearance in a coating

The present invention relates to a process for the production of a pattern having a three-dimensional appearance in a coating comprising flake-form effect pigments, to a coating produced in this way, and to the use thereof.. . ... Merck Patent Gmbh

12/07/17 / #20170348488

Auto injector with separate needle injection

An auto injector having sequential control of needle insertion and dose injection is disclosed. A syringe with a needle is movably positioned in a housing between a first position in which the needle is accommodated inside the housing and a second position in which the needle protrudes outside the housing. ... Merck Patent Gmbh

12/07/17 / #20170348487

Auto-injector for epinephrine injection

A reloadable auto injector for epinephrine injection is provided. The reloadable auto injector has a separate needle insertion and medicine injection drivers (1600) wherein needle insertion driver (1200) is configured to be re-activated upon reloading. ... Merck Patent Gmbh

12/07/17 / #20170348380

Intraarticular application of pepstatin in the case of arthrosis

The present invention relates to pharmaceutical preparations and medicaments for intraarticular administration, comprising pepstatin, and to the preparation and use thereof, in particular in the treatment and/or prophylaxis of arthrosis, traumatic cartilage injuries, arthritis, pain, allodynia or hyperalgesia, particularly preferably in arthrosis.. . ... Merck Patent Gmbh

11/30/17 / #20170343847

Light modulation element

. . The invention relates to a light modulation element comprising a cholesteric liquid crystalline medium sandwiched between two substrates, each provided with an electrode structure, wherein at least one of the substrates is additionally provided with an alignment layer which is provided with a photoresist pattern consisting of periodic substantially parallel stripes. The invention is further related to a method of production of said light modulation element and to the use of said light modulation element in various types of optical and electro-optical devices, such as electro-optical displays, liquid crystal displays (lcds), non-linear optic (nlo) devices, and optical information storage devices.. ... Merck Patent Gmbh

11/30/17 / #20170343712

A polarized light emissive device

The present invention relates to a polarized light emissive device and a method for its manufacture comprising a plural of fluorescent semiconductor quantum rods, and to a preparation thereof. The invention further relates to a use of the polarized light emissive device in optical devices, and to an optical device comprising the polarized light emissive device.. ... Merck Patent Gmbh

11/30/17 / #20170342372

Cell culture media

The present invention relates to dry cell culture media comprising amino acid components of certain particle size. Some dry powder cell culture media show poor dissolving properties and result in turbid solutions when they are dissolved in aqueous solutions. ... Merck Patent Gmbh

11/30/17 / #20170340989

Target molecule capture from crude solutions

The present invention refers to a method for the separation of peptide aggregates and fragments from solutions containing target peptide.. . ... Merck Patent Gmbh

11/30/17 / #20170340635

Combination of a 6-oxo-1,6-dihydro-pyridazine derivative having anti-cancer activity with a quinazoline derivative

A pharmaceutical composition of 3-(1-{3-[5-(1-methyl-piperidin-4-ylmethoxy)-pyrimidin-2-yl]-benzyl}-6-oxo-1,6-dihydro-pyridazin-3-yl)-benzonitrile or a pharmaceutically acceptable salt and/or solvate thereof in combination with 4-[(s)-2-azetidin-1-yl-1-(4-chloro-3-trifluoromethyl-phenyl)-ethylamino]-quinazoline-8-carboxylic acid amide.. . ... Merck Patent Gmbh








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