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Merck Patent Gmbh patents (2016 archive)


Recent patent applications related to Merck Patent Gmbh. Merck Patent Gmbh is listed as an Agent/Assignee. Note: Merck Patent Gmbh may have other listings under different names/spellings. We're not affiliated with Merck Patent Gmbh, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "M" | Merck Patent Gmbh-related inventors


Tbk/ikk inhibitor compounds and uses thereof

The present invention relates to compounds of formula i and pharmaceutically acceptable compositions thereof, useful as tbk/ikkε inhibitors.. . ... Merck Patent Gmbh

Process for producing inorganic particulate material

The present invention relates to a process for producing inorganic particulate material, the material obtainable by such process, a modified release delivery system comprising the material and the use of the material for the administration of a bioactive agent.. . ... Merck Patent Gmbh

Spiro-condensed lactam compounds for organic electroluminescent devices

The invention relates to polycondensed lactam compounds as materials for use in electronic devices, and electronic devices, in particular organic electroluminescent devices, containing said materials.. . ... Merck Patent Gmbh

Assays and monitoring paradigms for stem cell culture

The invention provides, inter alia, methods for monitoring the differentiation state of cultured cells, such as cultured mscs, as well as related kits and systems for performing the methods. In certain embodiments, the methods entail measuring the level of one or more of klf5, fabp4, adiponectin/adipoq, chemerin/rarres2, klf4, pai1, runx2, alpl, osteocalcin/bglap, ctnnb1, osteonectin/sparc, sox9, col2a1, mia, and comp.. ... Merck Patent Gmbh

Metal complexes

The present invention relates to metal complexes and to electronic devices, in particular organic electroluminescent devices, comprising these metal complexes.. . ... Merck Patent Gmbh

Polymerizable compounds and the use thereof in liquid-crystal displays

The present invention relates to polymerizable compounds, to processes and intermediates for the preparation thereof, to liquid-crystal media comprising them, and to the use of the polymerizable compounds and liquid crystalline media for optical, electro-optical and electronic purposes, in particular in liquid crystalline displays, especially in liquid crystalline displays of the polymer sustained alignment type.. . ... Merck Patent Gmbh

Novel heterocycles as modulators of kinase activity

The invention provides novel heterocyclic amines according to formula (i) their manufacture and use for the treatment of hyperproliferative diseases, such as cancer.. . ... Merck Patent Gmbh

Light emitting compounds

Claimed is a cyclometallated organometallic light emitting complex having two tridentate ligand portions sharing a central heterocycle “a” providing a binding-site for each of the two metals (formula i): formula (i): a more illustrative embodiment is formula (xii): characterizing for the invention is that either one of xi and x2 and either one of y1 and y2 is carbon. The dinuclear complexes are for use in oleds.. ... Merck Patent Gmbh

Preparation of semiconductor films

This invention relates to a precursor material, which can be decomposed to form semiconductors and metal oxides, or more generally, materials for electronic components. The precursors comprise metal complexes of hydroxamato ligands. ... Merck Patent Gmbh

Skin lightener in phototherapy

. . The invention relates, inter alia, to melanin synthesis inhibitors for use in treating skin illnesses, wherein the skin is additionally irradiated with an artificial radiation source. The invention further relates to cosmetic treatments.. ... Merck Patent Gmbh

Novel heterocyclic carboxamides as modulators of kinase activity

The invention provides novel heterocyclic carboxamide compounds compounds according to formula (i) their manufacture and use for the treatment of hyperproliferative diseases, such as cancer.. . ... Merck Patent Gmbh

Pigments

. . The present invention relates to pigments based on bismuth compounds and to the use thereof, preferably as laser-absorbent additive, and to a process for the preparation thereof.. . ... Merck Patent Gmbh

A 6-oxo-1,6-dihydro-pyridazine derivative for the use for the treatment of renal cell carcinoma (rcc)

3-(1-{3-[5-(1-methyl-piperidin-4-ylmethoxy)-pyrimidin-2-yl]-benzyl}-6-oxo-1,6-dihydro-pyridazin-3-yl)-benzonitrile or a pharmaceutically acceptable salt and/or solvate thereof for the use for the treatment of renal cell carcinoma (rcc).. . ... Merck Patent Gmbh

Photovoltaic cells

. . The invention relates to a photovoltaic cell that comprises a first electrode, a second electrode, and a photoactive layer between the first electrode and the second electrode, and to a preparation thereof. The invention further relates to the use of at least two specific donor materials in photovoltaic cells.. ... Merck Patent Gmbh

11/10/16 / #20160329507

9,9'-spirobixanthene derivatives for electroluminescent devices

The present invention relates to compounds suitable for use in electronic devices, and to electronic devices, especially organic electroluminescent devices, comprising these compounds.. . ... Merck Patent Gmbh

11/10/16 / #20160326429

Materials for organic electroluminescent devices

The invention relates to compounds which can be used in electronic devices, and to electronic devices, in particular organic electroluminescent devices, containing said compounds.. . ... Merck Patent Gmbh

11/10/16 / #20160326091

Use of cyclohexanol derivatives as antimicrobial active compounds

The present invention relates to the use of at least one cyclohexanol derivative of the formula (i) and/or (ii) as antimicrobial active compound or as anti-acne, antidandruff, antiperspirant or deodorant active compound, to preparations comprising these compounds, and to specific cyclohexanol derivatives and to a process for the preparation thereof.. . ... Merck Patent Gmbh

11/10/16 / #20160325231

Process for the purification of a liquid-crystal mixture

In a process for the purification of a liquid-crystal mixture (7), the liquid-crystal mixture (7) is passed through a first electrodialysis cell (2) and a concentrate solution (14) is passed through a second electrodialysis cell (8) which is adjacent to the first electrodialysis cell (2) and is separated by an ion-exchanger membrane (9), and an electric field transverse to a direction of passage of the liquid-crystal mixture (7) through the first electrodialysis cell (2) is generated with the aid of an anode/cathode arrangement (15, 16) arranged outside the electrodialysis cells (2, 8) so that ionised constituents of the liquid-crystal mixture (7) are discharged at the ion-exchanger membrane (9) and removed from the liquid-crystal mixture (7).. . ... Merck Patent Gmbh

11/10/16 / #20160324855

Combination of a 6-oxo-1,6-dihydro-pyridazine derivative having anti-cancer activity with gefitinib

A pharmaceutical composition of 3-(1-{3-[5-(1-methyl-piperidin-4-ylmethoxy)-pyrimidin-2-yl]-benzyl}-6-oxo-1,6-dihydro-pyridazin-3-yl)-benzonitrile or a pharmaceutically acceptable salt and/or solvate thereof in combination with gefitinib.. . ... Merck Patent Gmbh

11/03/16 / #20160322570

Organic electroluminescent device

. . . . The present invention relates to the use of aromatic boronic acid or borinic acid derivatives in organic electronic devices, in particular electroluminescent devices.. . ... Merck Patent Gmbh

11/03/16 / #20160319592

Device for regulating the passage of light

The present application relates to a device for regulating the passage of light which is characterised in that it comprises a layer comprising a liquid-crystalline mixture containing a characteristic structural element.. . ... Merck Patent Gmbh

11/03/16 / #20160318325

Method for producing a marking

The present invention relates to a method for producing a marking in a coating on a substrate or on the surface of a moulding, where the marking represents a negative marking within a luminescent surrounding field and is generated using a laser beam, to a marking produced with the aid of the method, and to the use thereof, in particular for the labeling of products.. . ... Merck Patent Gmbh

11/03/16 / #20160317948

Purification device

A purification device (1), for the purification of a liquid-crystal mixture, has a flow chamber (2) which has an inlet opening (3) and an outlet opening (4), arranged opposite the inlet opening, in order to be able to introduce the liquid-crystal mixture into the flow chamber (2) and discharge it from the latter, and at least one flow distribution element (5) which is arranged in the flow chamber (2) in the region of the inlet opening (3), and at least one filter element (6) which is arranged in the region of the outlet opening (4), where a length of the flow chamber (2) measured in the flow direction is at least a factor of 2 greater than a greatest internal dimension of the flow chamber (2) transverse to the flow direction.. . ... Merck Patent Gmbh

10/27/16 / #20160313624

Electrophoretic fluid

This invention relates to electrophoretic fluids comprising a solvent, a dye, white particles, and coloured particles selected from red, green, blue, magenta, cyan, yellow particles, and mixtures thereof, and electrophoretic display devices comprising such fluids.. . ... Merck Patent Gmbh

10/27/16 / #20160312378

Method for the production of single crystalline mgtio3 flakes

The present invention is related to a method for the production of single crystalline mgtio3 flakes, in particular in the geikielite crystal structure, to single crystalline mgtio3 flakes obtained by this method as well as to the use thereof, in particular as pigments in several application media.. . ... Merck Patent Gmbh

10/27/16 / #20160311830

Tetrahydro-tetrazolo[1,5-a]pyrazines as ror-gamma inhibitors

The present invention relates to tetrahydro-tetrazolo[1,5-a]pyrazine compounds of formula (i), wherein r1 denotes —r3, —ch2—r3 or —co—r3; r2 denotes ar2, hetar2 or c3-7-cycloalkyl; and r3 denotes ar3, hetar3 or c3-7-cycloalkyl. These compounds are useful for inhibiting the retinoid-related orphan receptor γ (ror γ, ror-gamma) and for the prevention and/or treatment of medical conditions affected by ror γ activity such as rheumatoid arthritis, multiple sclerosis, psoriasis, ulcerative colitis, asthma, autoimmune hepatitis or type 1 and type 2 diabetes.. ... Merck Patent Gmbh

10/27/16 / #20160311798

N1-(3,3,3-trifluoro-2-hydroxo-2-methylpropionyl)-piperidine derivatives as inhibitors of pyruvate dehydrogenase kinase

Compounds of the formula (i) in which r, r1 and r3 have the meanings indicated in claim 1, are inhibitors of pyruvate dehydrogenase kinase (pdhk), and can be employed, inter alia, for the treatment of diseases such as cancer.. . ... Merck Patent Gmbh

10/20/16 / #20160308149

Metal complexes and use thereof in electronic devices

The present invention relates metal complexes and to electronic devices, particularly organic electroluminescent devices containing said metal complexes.. . ... Merck Patent Gmbh

10/20/16 / #20160308147

Heterocyclic spiro compounds

The present invention relates to spiro compounds containing electron-conducting groups and to electronic devices, in particular organic electroluminescent devices, comprising these compounds.. . ... Merck Patent Gmbh

10/20/16 / #20160308146

Substituted oxepines

The invention relates to materials, to electroluminescence devices comprising said materials and to the use thereof.. . ... Merck Patent Gmbh

10/20/16 / #20160308129

Materials for electronic devices

The present invention relates to compounds of the formula (1), which are suitable for use in electronic devices, in particular in organic electroluminescent devices.. . ... Merck Patent Gmbh

10/20/16 / #20160304779

Eu2+-activated phosphors

The invention relates to eu2+-activated phosphors, to a process of its preparation, the use of these phosphors in electronic and electro optical devices, such as light emitting diodes (leds) and solar cells and especially to illumination units comprising said magnesium alumosilicate-based phosphors.. . ... Merck Patent Gmbh

10/20/16 / #20160303228

Silicon dioxide nanoparticles and the use thereof for vaccination

The invention relates to ultrasmall, monodisperse nanoparticles comprising silicon dioxide to the surface of which at least one antigen is attached. The nanoparticles can be used for the immunoprophylaxis or immunotherapy of cancer. ... Merck Patent Gmbh

10/13/16 / #20160301016

Compound with novel six-membered ring structure for use in organic electronic devices

. . . . . . The present invention relates to novel compounds according to formula (i) having a six-membered ring structure substituted with electron donor, electron acceptor and sterically demanding groups. Said compound is suited for use in organic electronic devices, particularly in organic electroluminescent devices (oleds). ... Merck Patent Gmbh

10/13/16 / #20160301008

Novel polycyclic polymer comprising thiophene units, a method of producing and uses of such polymer

The present invention relates to a novel polycyclic polymer comprising fused thiophene units. The present invention also relates to a method for producing such polymer as well as the use of such polymer, particularly in organoelectronic applications.. ... Merck Patent Gmbh

10/13/16 / #20160301005

Compounds and organic electronic devices

The present invention relates to certain fluorenes, to the use of the compounds in an electronic device, and to an electronic device comprising at least one of these compounds. Furthermore, the present invention relates to a process for the preparation of the compounds and to a formulation and composition comprising one or more of the compounds.. ... Merck Patent Gmbh

10/13/16 / #20160301003

Compositions containing a polymeric binder which comprises acrylic and/or methacrylic acid ester units

The present invention relates to novel compositions comprising organic light emitting materials and/or charge transporting materials and a polymeric binder which comprises acrylic and/or methacrylic acid ester units, to their use as conducting inks for the preparation of organic light emitting diode (oled) devices, to methods for preparing oled devices using the novel formulations, and to oled devices prepared from such methods and formulations.. . ... Merck Patent Gmbh

10/13/16 / #20160296509

Novel quinoline derivatives and their use in neurodegenerative diseases

The present invention relates to quinoline compounds, and pharmaceutically acceptable compositions thereof, useful as antagonists of p2x7, and for the treatment of p2x7-related disorders.. . ... Merck Patent Gmbh

10/06/16 / #20160293289

Method for structuring a transparent conductive matrix comprising nano materials

. . The present invention refers to a method for selectively structuring of a polymer matrix comprising agnws (silver nano wires) or silver nano particles (ag nano ink) or comprising mixtures of agnws and silver nano particles on a flexible plastic substructure or solid glass sheet. The method also includes a suitable etching composition, which allows to process the method in an industrial scale.. ... Merck Patent Gmbh

10/06/16 / #20160289859

Method for the production of single crystalline tio2 flakes

The present invention is related to a method for the production of single crystalline tio2 flakes in the rutile crystal structure, to single crystalline tio2 flakes obtained by this method as well as to the use thereof, especially as pigments in several application media.. . ... Merck Patent Gmbh

09/29/16 / #20160279213

Survivin-directed cancer vaccine therapy

. . The invention relates to a therapeutically effective truncated survivin and its therapeutic use as vaccine in a liposomal preparation, wherein the survivin fragment is preferably gluconoylated, and said liposomal preparation elicits in-vivo anti-tumor activity. The invention is directed, in more detail, to a cancer vaccine comprising a fragment of human survivin that is specifically effective in conjunction with an lipid adjuvant. ... Merck Patent Gmbh

09/22/16 / #20160276591

Conjugated polymers

The invention relates to novel conjugated polymers containing one or more diindeno-thieno[3,2-b]thiophene based polycyclic repeating units, to methods for their preparation and educts or intermediates used therein, to polymer blends, mixtures and formulations containing them, to the use of the polymers, polymer blends, mixtures and formulations as organic semiconductors in organic electronic (oe) devices, especially in organic photovoltaic (opv) devices and organic photodetectors (opd), and to oe, opv and opd devices comprising these polymers, polymer blends, mixtures or formulations.. . ... Merck Patent Gmbh

09/22/16 / #20160272837

Electrically conductive pigment

The present invention relates to electrically conductive pigments, to a process for the preparation thereof and to the use thereof, in particular in antistatic or dissipative articles or surfaces, for example in paints, coatings, printing inks or floorcoverings.. . ... Merck Patent Gmbh

09/22/16 / #20160272753

Conjugated polymers

Disclosed are novel conjugated polymers containing one or more 3,4-dithia-7-sila-cyclopenta[a]pentalene based units and one or more pyrazino[2,3-g]quinoxaline based units, methods for their preparation and educts or intermediates used therein, polymer blends, mixtures and formulations containing them, the use of the polymers, polymer blends, mixtures and formulations as organic semiconductors in organic electronic (oe) devices, especially in organic photovoltaic (opv) devices and organic photodetectors (opd), and to oe, opv and opd devices containing these polymers, polymer blends, mixtures or formulations.. . ... Merck Patent Gmbh

09/22/16 / #20160272346

Filling device and use thereof for dispensing a fluid

The invention relates to a filling device (1) for dispensing a fluid into at least one container, where the filling device (1) has a weighing system (2) and a filling-needle system (3). The weighing system (2) has a positioning device (4) which can be adapted to a container diameter and which may have an annular design. ... Merck Patent Gmbh

09/15/16 / #20160268509

Materials for electronic devices

. . . . . . The invention relates to compounds according to formula (1), said compounds being suitable for use in electronic devices, in particular in organic electroluminescent devices.. . ... Merck Patent Gmbh

09/15/16 / #20160267337

Detector array for vein recognition technology

Disclosed is a detector array for vein recognition technology, which contains an absorber of radiation, a security system that contains the detector array as well as a method for vein recognition.. . ... Merck Patent Gmbh

09/15/16 / #20160264862

Silicate phosphors

The invention relates to europium-doped silicate phosphors comprising a coating of aluminum oxide, to a process for the preparation of these compounds, and to the use thereof as conversion phosphors or in lamps.. . ... Merck Patent Gmbh

09/15/16 / #20160264720

Method for the production of polymers

The present invention relates to a process for preparing polymers by polycondensation catalysed by transition metals. These polymers are of great importance in, in particular, the fast-growing field of organic semiconductors. ... Merck Patent Gmbh

09/15/16 / #20160264548

Heteroaryl compounds as btk inhibitors and uses thereof

The present invention relates to pyridine, pyrimidine, pyrazine, and pyridazine compounds, and pharmaceutically acceptable compositions thereof, useful as btk inhibitors.. . ... Merck Patent Gmbh

09/08/16 / #20160260911

Materials for electronic devices

The present invention relates to an electronic device comprising anode, cathode and at least one organic layer which comprises a compound of the formula (i) to (iv). The invention furthermore encompasses the use of compounds of the formula (i) to (iv) in an electronic device and to a compound of the formula (ic) to (ivc).. ... Merck Patent Gmbh

09/08/16 / #20160257987

Method for isolating microorganisms from a complex sample

The present invention relates to a method for isolating and optionally detecting microorganisms from a sample comprising mammalian cells, comprising the use of a lysis buffer comprising benzonase® nuclease. The invention further relates to a lysis buffer comprising benzonase® nuclease and its use.. ... Merck Patent Gmbh

09/08/16 / #20160257885

Device for regulating the entry of light

The application relates to a device for regulating the entry of light into a room, which comprises a switchable layer of specific design comprising a twisted nematic liquid-crystalline medium and a dichroic compound.. . ... Merck Patent Gmbh

09/08/16 / #20160256053

Radiative fibers

The present invention relates inter alia to light emitting fibers for the application in general lighting, display backlit, information display, and for treatment and/or prophylaxis and/or diagnosis of diseases and/or cosmetic conditions. The fibers can be used for the preparation of any kind of canvas and light emitting devices.. ... Merck Patent Gmbh

09/01/16 / #20160254456

Materials for electronic devices

The invention relates to compounds with benzindenofluorene base bodies and to the use thereof in electronic devices, in particular in organic electroluminescent devices.. . ... Merck Patent Gmbh

09/01/16 / #20160254449

Hole transport material

The invention relates to 2,2′,7,7′-tetrakis-(n,n′-di-4-methoxy-3-methylphenylamine)-9,9′-spirofluorene, to a process for its preparation, and to its use as hole transport material for electronic or optoelectronic devices, especially for solid-state dye-sensitized solar cells.. . ... Merck Patent Gmbh

09/01/16 / #20160251492

Pigments based on bismuth compounds

The present invention relates to pigments based on bismuth compounds and to the use thereof, preferably as laser-absorbing additive, and to a process for the preparation thereof.. . ... Merck Patent Gmbh

09/01/16 / #20160251387

Synthesis of 1-alkyl-2-amino-imidazol-5-carboxylic acid ester via calpha-substituted n-alkyl-glycine ester derivatives

The invention provides an efficient and high yielding process for preparing th-302, comprising at least one step wherein a dioxolane intermediate is generated in an aqueous layer, resulting in a synthesis that is amenable to scale up conditions.. . ... Merck Patent Gmbh

09/01/16 / #20160250236

Predictive biomarker for hypoxia-activated prodrug therapy

Cyp2w1 levels are predictive of the probability that a cancer patient will respond favorably to cancer therapy involving administration of a hypoxia-activated achiral phosphoramidate mustards.. . ... Merck Patent Gmbh

08/25/16 / #20160248023

Materials for electronic devices

Compounds of formula (1) that have functional substituents in a specific spatial arrangement, and electronic devices that include a compound of formula (1), and to the preparation of compounds of formula (1).. . ... Merck Patent Gmbh

08/25/16 / #20160248015

Boron-containing compounds

The invention relates to boron-containing compounds with bicyclic structural units and to electronic devices, in particular organic electroluminescent devices, containing said compounds. . ... Merck Patent Gmbh

08/25/16 / #20160248014

Azaborinine derivatives, their synthesis and use in organic electronic devices

The present invention relates to azaborinine derivatives their synthesis as well as their use in organic electronic devices, particularly in organic light emitting devices, organic photovoltaic devices and organic photodetectors. The invention further relates to organic electronic devices comprising the present azaborinine derivatives. ... Merck Patent Gmbh

08/25/16 / #20160244671

Method of preparing a birefringent polymer film

The invention relates to a method of preparing a polymer film and to the use of such polymer film as in liquid crystal displays (lcds) or other optical or electro optical devices, for decorative or security applications, as alignment layer or optical retardation film. . ... Merck Patent Gmbh

08/25/16 / #20160244665

Phosphors

The present invention relates to cerium-doped garnet phosphors. The present invention furthermore relates to a process for the preparation of cerium-doped garnet phosphors, and to the use of these garnet phosphors as conversion phosphors. ... Merck Patent Gmbh

08/18/16 / #20160240782

Materials for organic electroluminescence device

The present invention relates to the compounds of the formula (1) and to organic electronic devices in which these compounds are used as matrix material in the emitting layer and/or as hole-transport material and/or as electron-blocking or exciton-blocking material and/or as electron-transport material.. . ... Merck Patent Gmbh

08/11/16 / #20160233444

Polycyclic phenylpyridine iridium complexes and derivatives thereof for oleds

. . The present invention relates to metal complexes for use in electronic devices, and to electronic devices, especially organic electroluminescent devices, comprising these metal complexes, especially as emitters. The compounds claimed have the formula: m(l)n(l′)m formula (1), where the compound of the general formula (1) contains a substructure m(l)n of the formula (2) or formula (3), where a is the same or different at each instance and is a group of the formula (a) which follows. ... Merck Patent Gmbh

08/11/16 / #20160233443

Metal complexes

The invention relates to metal complexes and to electronic devices, in particular organic electroluminescence devices, containing said metal complexes.. . ... Merck Patent Gmbh

08/11/16 / #20160230012

Pigment mixture, and use thereof in cosmetics, food and pharmaceuticals

The invention relates to pigment mixtures comprising at least two components a and b. The inventive pigment mixtures are characterized in that component a is embodied as effect pigments while component b is embodied as coloring agents and fillers. ... Merck Patent Gmbh

08/11/16 / #20160229871

Pyridazinone macrocycles as irak inhibitors and uses thereof

The present invention relates to compounds of formula i and pharmaceutically acceptable compositions thereof, useful as irak inhibitors.. . ... Merck Patent Gmbh

08/11/16 / #20160229856

Macrocyclic compounds as irak1/4 inhibitors and uses thereof

The present invention relates to compounds of formula i and pharmaceutically acceptable compositions thereof, useful as irak inhibitors.. . ... Merck Patent Gmbh

08/11/16 / #20160228551

Method of treating disorders using a pharmaceutical composition of oligopeptides

The present invention relates to a pharmaceutical composition of oligopeptides, preferably cyclic oligopeptides, said composition further comprising one or more lipophilic and/or amphiphilic compounds, in the presence or absence of water as the main ingredients, the use of the lipophilic and/or amphiphilic compounds for making pharmaceutical compositions of said oligopeptides, and methods of making said pharmaceutical composition.. . ... Merck Patent Gmbh

08/11/16 / #20160228493

Aminostatin derivatives for the treatment of arthrosis

The present invention relates to compounds of the formula (i) and in particular medicaments comprising at least one compound of the formula (i) for use in the treatment and/or prophylaxis of physiological and/or pathophysiological states in the triggering of which cathepsin d is involved, in particular for use in the treatment and/or prophylaxis of arthrosis, traumatic cartilage injuries, arthritis, pain, allodynia or hyperalgesia.. . ... Merck Patent Gmbh

08/04/16 / #20160226003

Heterocyclic compounds

. . The invention concerns heterocyclic compounds and electronic devices, in particular organic electroluminescent devices, containing these compounds.. . ... Merck Patent Gmbh

08/04/16 / #20160226001

Organic electroluminescent device

The invention relates to an organic electroluminescent device (oled) containing an emitting layer which contains a compound having a small difference between the s1 and the t1 energy levels and to another compound of formula (i) or (ii).. . ... Merck Patent Gmbh

08/04/16 / #20160222213

Interference pigments

The present invention relates to interference pigments based on transparent, low-refractive-index, flake-form substrates which have a high-refractive-index coating consisting of tio2 having a layer thickness of 20-200 nm and optionally an outer protective layer, and to the use thereof in paints, coatings, printing inks, security printing inks, plastics, button pastes, ceramic materials, glasses, for seed coloring, as dopants in the laser marking of plastics and papers, as additive for the laser welding of plastics, as additive for coloring in the foods and pharmaceuticals sectors, and in cosmetic formulations and for the preparation of pigment compositions and dry preparations.. . ... Merck Patent Gmbh

07/28/16 / #20160218185

Liquid doping media for the local doping of silicon wafers

The present invention relates to a novel process for the preparation of printable, low-viscosity oxide media, and to the use thereof in the production of solar cells.. . ... Merck Patent Gmbh

07/28/16 / #20160216177

Filter device for filtering complex fluid samples

A filter device (1) for filtering complex fluid samples, comprising a first filter funnel (2) having an inlet (2a) an outlet (2b) and a first internal space (2c) and a second filter funnel (3) having an inlet (3a), an outlet (3b) and a second internal space (3c). The first and second filter funnels (2,3) are sequentially arranged with a first filter medium (4) located therebetween such that the volume of sample fluid placed in the first internal space (2c) can pass through the first filter medium (4) and be collected in the second internal space (3c). ... Merck Patent Gmbh

07/28/16 / #20160215216

Polymerisable liquid crystal material and polymerised liquid crystal film

The invention relates to a polymer film comprising a polymerised liquid crystal (lc) material with improved adhesion to a substrate, to methods for preparing such a polymer film, to a polymerisable lc material used for the preparation of such a polymer film, and to the use of the polymer film and said polymerisable lc material for optical, electrooptical, decorative or security uses and devices.. . ... Merck Patent Gmbh

07/28/16 / #20160215214

Liquid-crystal medium

Disclosed are a liquid crystal (lc) medium containing a polymerisable compound, a process for its preparation, its use for optical, electro-optical and electronic purposes, in particular in lc displays, especially in an lc display of the polymer sustained alignment (psa) type, and to an lc display, especially a psa display.. . ... Merck Patent Gmbh

07/28/16 / #20160214942

Triarylamine-substituted benzo[h]quinoline-derivatives as materials for electronic devices

The invention relates to a heteroaryl compound according to formula (i) and to the use thereof in electronic devices.. . ... Merck Patent Gmbh

07/21/16 / #20160211468

Metal complexes

. . . . The present invention relates to metal complexes, to compositions and formulations comprising these complexes, and to devices comprising the complexes or compositions.. . ... Merck Patent Gmbh

07/21/16 / #20160208386

Precursors for the production of thin oxide layers and the use thereof

The present invention relates to novel precursors in the form of metal complexes with 2-substituted 1,3-diketones and to a process for the preparation thereof. The invention furthermore relates to the use thereof for the production of thin metal-oxide layers. ... Merck Patent Gmbh

07/21/16 / #20160207967

Phl p 5a derivatives having reduced allergeneity and retained t-cell reactivity

The present invention relates to the preparation and use of variants of the group 5 allergen of the pooideae which are characterised by reduced ige reactivity compared with the known wild-type allergens and at the same time by substantially retained reactivity with t lymphocytes. These hypoallergenic allergen variants can be employed for the specific immunotherapy (hyposensitisation) of patients having grass pollen allergy or for the preventative immunotherapy of grass pollen allergies.. ... Merck Patent Gmbh

07/21/16 / #20160207344

Printed image

The present invention relates to a printed image comprising flake-form effect pigments which has striking matt/gloss effects, to a process for the production of a printed image of this type, and to the use thereof, in particular in security printing.. . ... Merck Patent Gmbh

07/21/16 / #20160206530

Special effects with mixtures of interference pigments

A method of producing mixtures of interference pigments having special effects comprises mixing at least one large particle size interference pigment with at least one normal size interference pigment of predetermined colors and in proportions desired to obtain a unique effect.. . ... Merck Patent Gmbh

07/14/16 / #20160204358

Polycyclic compounds

. . . . The present invention relates to compounds having polycyclic structural units and to electronic devices, in particular organic electroluminescent devices, containing said compounds.. . ... Merck Patent Gmbh

07/14/16 / #20160199505

Peptides and peptide/active compound conjugates for renal targeting

The present invention relates to a peptide which consists of more than 50% of sequence sections of the formula -(an-bm-co)-, and to a conjugate containing the peptide and at least one covalently bonded active compound, and to a process for the preparation of the conjugate. The present invention furthermore relates to the use of the peptide and the conjugate for targeting of the kidney, and to a medicament comprising the peptide or conjugate.. ... Merck Patent Gmbh

07/14/16 / #20160199492

Diffusion pigments in phototherapy

The present invention relates to the use of microfine pigments in medical and cosmetic phototherapy.. . ... Merck Patent Gmbh

07/07/16 / #20160197280

Composition comprising polymeric organic semiconducting compounds

The present invention relates to novel compositions comprising one or more polymeric organic semiconducting (osc) compounds and one or more organic solvents. The composition preferably comprises 3,4-dimethyl anisole as solvent. ... Merck Patent Gmbh

07/07/16 / #20160197275

Emitter having a condensed ring system

The present invention relates to organic electroluminescent devices which comprise aromatic ring systems with two or three condensed rings as emitter materials, and to their possible uses.. . ... Merck Patent Gmbh

07/07/16 / #20160194380

Potent inhibitors of human matriptase derived from mcoti-ii variants

The present invention pertains to highly potent matriptase inhibitors derived from the miniprotein mcoti-ii.. . ... Merck Patent Gmbh

06/16/16 / #20160169894

Assays for btk inhibitors

. . . . The present invention relates to btk occupancy assays.. . ... Merck Patent Gmbh

06/16/16 / #20160168090

Novel indole derivatives and their use in neurodegenerative diseases

The present invention relates to indole compounds, and pharmaceutically acceptable compositions thereof, useful as antagonists of p2x7, and for the treatment of p2x7-related disorders.. . ... Merck Patent Gmbh

06/16/16 / #20160167972

Compounds containing hydrido-tricyano-borate anions

The present invention relates to intermediate compounds for the preparation of hydrido-tricyano-borate anions, their preparation and their uses.. . ... Merck Patent Gmbh

06/09/16 / #20160164002

Materials for electronic devices

The invention relates to compounds with functional substitutes in a specific spatial arrangement, to devices containing said functional substitutes and to the production and use thereof.. . ... Merck Patent Gmbh

06/09/16 / #20160163987

Electro-optical device and the use thereof

The present invention relates to an electro-optical device containing a) an anode, b) a cathode and c) at least one first emitter layer arranged between anode and cathode, containing at least one semiconducting, organic material, said device being characterized in that at least one second emitter layer comprising at least one polymer having hole-conducting properties and at least one emitter is arranged between the first emitter layer and the anode, and to the use thereof. The use of two emitter layers allows simple production from solution, and the production of electroluminescence devices having broadband emission.. ... Merck Patent Gmbh

06/09/16 / #20160161780

Fail safe mechanism for switchable window

An optical device, having an active matrix, containing polymer dispersed liquid crystals, guest-host liquid crystals, suspended particles and/or polymer stabilized cholesteric liquid crystals, the active high transmissive mode has at least 40% of incoming light transmitted through the optical device and in low transmissive mode less than 40% of incoming light transmitted through the optical device, the active matrix is switchable between high transmissive mode and low transmissive mode. The optical device containing a fail-safe mechanism, which is capable to switch the active matrix from a low transmissive mode in a high transmissive mode without the power of an applied grid.. ... Merck Patent Gmbh

06/09/16 / #20160159804

Pyridines, pyrimidines, and pyrazines, as btk inhibitors and uses thereof

The present invention relates to pyridine, pyrimidine, and pyrazene compounds, and pharmaceutically acceptable compositions thereof, useful as btk inhibitors.. . ... Merck Patent Gmbh

06/09/16 / #20160159763

Polymerizable compounds and the use thereof in liquid-crystal displays

The present invention relates to polymerisable compounds, to processes and intermediates for the preparation thereof, and to the use thereof for optical, electro-optical and electronic purposes, in particular in liquid-crystal (lc) media and lc displays, especially in lc displays of the ps (“polymer sustained”) or psa (“polymer sustained alignment”) type.. . ... Merck Patent Gmbh

06/09/16 / #20160158253

Treatment of pancreatic cancer with a combination of a hypoxia-activated prodrug and a taxane

Combined administration of a hypoxia-activated prodrug, such as th-302, a taxane, such as nab-paclitaxel, and a nucleoside analog chemotherapeutic, such as gemcitabine, are efficacious in the treatment of cancer, including pancreatic cancer.. . ... Merck Patent Gmbh

06/02/16 / #20160155959

Organic electroluminescent device

. . The present invention relates to organic electroluminescent devices which comprise a mixture of an iridium complex and a triazine or pyrimidine compound in the emitting layer.. . ... Merck Patent Gmbh

06/02/16 / #20160155946

Conjugated polymers

The invention relates to novel conjugated polymers containing one or more [1,2,5]thiadiazolo[3,4-e]isoindole-5,7-dione (tid) repeating units, to methods for their preparation and educts or intermediates used therein, to polymer blends, mixtures and formulations containing them, to the use of the polymers, polymer blends, mixtures and formulations as organic semiconductors in, or for the preparation of, organic electronic (oe) devices, especially organic photovoltaic (opv) devices and organic photodetectors (opd), and to oe, opv and opd devices comprising, or being prepared from, these polymers, polymer blends, mixtures or formulations.. . ... Merck Patent Gmbh

06/02/16 / #20160152894

Liquid crystal medium

The present invention relates to a liquid crystal (lc) medium comprising a terphenyl compound and at least two polymerisable compounds, to a process for its preparation, to its use for optical, electro-optical and electronic purposes, in particular in lc displays, especially in an lc display of the polymer sustained alignment (psa) type, and to an lc display, especially a psa display, comprising it.. . ... Merck Patent Gmbh

06/02/16 / #20160152626

Pyrazole compounds as modulators of fshr and uses thereof

The present invention relates to pyrazole compounds, and pharmaceutically acceptable compositions thereof, useful as positive allosteric modulators of follicle stimulating hormone receptor (fshr).. . ... Merck Patent Gmbh

06/02/16 / #20160152609

Imidazole compounds as modulators of fshr and uses thereof

The present invention relates to imidazole compounds, and pharmaceutically acceptable compositions thereof, useful as positive allosteric modulators of follicle stimulating hormone receptor (fshr).. . ... Merck Patent Gmbh

06/02/16 / #20160152546

Polymerisable compounds and the use thereof in liquid-crystal media and liquid-crystal displays

The present invention relates to polymerisable compounds, to processes and intermediates for the preparation thereof, to the use thereof for optical, electro-optical and electronic purposes, in particular in liquid-crystal (lc) media and lc displays having a polymer-stabilised blue phase, and in lc media for lc displays of the ps or psa type (“polymer sustained” or “polymer sustained alignment”), and to lc media and lc displays comprising these compounds.. . ... Merck Patent Gmbh

05/26/16 / #20160147100

Optical device with power supply system

The invention pertains to an optical device comprising at least one glass or polymer area, whereby an active matrix is located in contact with the at least one glass or polymer area, the optical device comprises a power supply system located between a first auxiliary plane and a second auxiliary-plane parallel to a glass or polymer area, and a distance l from a third auxiliary-plane or a fourth auxiliary-plane approximately perpendicular to the glass or polymer area. The invention pertains also to a power supply system for such an optical device.. ... Merck Patent Gmbh

05/26/16 / #20160145565

Cell culture media

The present invention relates to cell culture media comprising polymer embedded components. Some components show poor stability in dry powder cell culture media. ... Merck Patent Gmbh

05/26/16 / #20160145421

Microspheres

The present invention relates to microspheres, to a process for the production thereof, and to the use thereof, preferably as laser-absorbing additive.. . ... Merck Patent Gmbh

05/26/16 / #20160145297

Hydroxy-ethylene derivatives for the treatment of arthrosis

The present invention relates to compounds of the formula i and in particular medicaments comprising at least one compound of the formula i for use in the treatment and/or prophylaxis of physiological and/or pathophysiological conditions in the triggering of which cathepsin d is involved, in particular for use in the treatment and/or prophylaxis of arthrosis, traumatic cartilage injuries, arthritis, pain, allodynia or hyperalgesia.. . ... Merck Patent Gmbh

05/26/16 / #20160145252

Heteroaryl compounds as irak inhibitors and uses thereof

The present invention relates to compounds of formula i and pharmaceutically acceptable compositions thereof, useful as irak inhibitors.. . ... Merck Patent Gmbh

05/19/16 / #20160141508

Materials for electronic devices

. . The present invention relates to a compound of a formula (i), in which an electron-deficient group and an arylamino group are connected to one another via an intermediate group. The compound of the formula (i) is suitable as functional material in electronic devices.. ... Merck Patent Gmbh

05/19/16 / #20160137923

Liquid crystal medium

The present invention relates to a liquid crystal (lc) medium comprising a terphenyl compound and at least two polymerizable compounds, to a process for its preparation, to its use for optical, electro-optical and electronic purposes, in particular in lc displays, especially in an lc display of the polymer sustained alignment (psa) type, and to an lc display, especially a psa display, comprising it.. . ... Merck Patent Gmbh

05/19/16 / #20160137847

Transparent, optically variable interference pigments having electrically semiconducting properties

The present invention relates to transparent, optically variable, electrically semiconducting interference pigments, in particular flake-form interference pigments, which comprise an oxygen-deficient layer of ti02-x, to a process for the preparation of such pigments, and to the use of the pigments prepared in this way.. . ... Merck Patent Gmbh

05/19/16 / #20160137846

Transparent, electrically semiconducting interference pigments with high color strength

The present invention relates to transparent, electrically semiconducting interference pigments having high colour strength, and in particular to flake-form interference pigments which comprise an oxygen-deficient layer of tio2-x, to a process for the preparation of such pigments, and to the use of the pigments prepared in this way.. . ... Merck Patent Gmbh

05/12/16 / #20160133863

Formulation and method for preparation of organic electronic devices

. . The present invention relates to novel formulations comprising an organic semiconductor (osc) and one or more organic solvents. The formulation comprises a viscosity at 25° c. ... Merck Patent Gmbh

05/12/16 / #20160133854

Materials for electronic devices

The present invention relates to a compound, comprising a pyrene skeleton and arylamino groups, according to formula (i). The compound is suitable for use as a functional material in electronic devices.. ... Merck Patent Gmbh

05/12/16 / #20160130286

Method for producing salts having monofluoro-tricyanoborate anions

The invention relates to a method for producing alkali metal salts having monofluoro-tricyanoborate anions from alkali metal tetrafluoroborates.. . ... Merck Patent Gmbh

05/12/16 / #20160130285

Method for producing salts having hydridocyanoborate anions

The invention relates to a method for producing alkali metal salts having monohydrido-tricyanoborate anions from alkali metal monofluorotricyanoborates, and to a method for producing alkali metal salts having dihydrido-dicyanoborate anions from alkali metal difluorodicyanoborates.. . ... Merck Patent Gmbh

05/12/16 / #20160130269

7-azaindole derivatives

Compounds of the formula (i) in which r, r1, r2 and r3 have the meanings indicated in claim 1, are inhibitors of pdk1 and cell proliferation/cell vitality and can be employed for the treatment of tumors.. . ... Merck Patent Gmbh

05/05/16 / #20160126480

Metal complexes

The present invention relates to metal complexes in accordance with formula (1), to use thereof in electronic devices and to electronic devices, particularly organic electroluminescent devices, containing said metal complexes.. . ... Merck Patent Gmbh

05/05/16 / #20160122297

Fluorosurfactants in pesticides

The present invention relates to the use of fluorinated surfactants of formula (i) in pesticides.. . ... Merck Patent Gmbh

04/28/16 / #20160116652

Method for controlling the optical properties of uv filter layers

. . . . . . The invention relates to a method for controlling the optical properties of uv filter layers, in particular for controlling the uv absorption properties of metal oxide-containing uv filter layers, to uv filter layers produced thereby, and to the use thereof, in particular for the production of electronic components.. . ... Merck Patent Gmbh

04/28/16 / #20160114054

Conjugates for protection from nephrotoxic active substances

The present invention relates to a conjugate containing at least one kidney-selective carrier molecule and at least one active compound which has a protective action for the kidney against nephrotoxic active compounds, to a process for the preparation of the conjugate, to the use thereof for the protection of the kidney against nephrotoxic active compounds, and to a medicament comprising the conjugate.. . ... Merck Patent Gmbh

04/07/16 / #20160096834

Heteroaryl compounds as btk inhibitors and uses thereof

The present invention relates to imidazo pyridine compounds, and pharmaceutically acceptable compositions thereof, useful as btk inhibitors.. . ... Merck Patent Gmbh

04/07/16 / #20160096809

Materials for organic electroluminescent devices

The present invention relates to fluorene derivatives and to electronic devices in which these compounds are used as matrix material in the emitting layer and/or as hole-transport material and/or as electron-blocking or exciton-blocking material and/or as electron-transport material.. . ... Merck Patent Gmbh

03/31/16 / #20160093813

Organic electroluminescent device

. . The present invention relates to organic electroluminescent devices which comprise mixtures of at least one matrix material of the formula (1) and an emitting material which has a small singlet-triplet separation.. . ... Merck Patent Gmbh

03/31/16 / #20160093812

Organic electroluminescent device

The present invention relates to organic electroluminescent devices which comprise a luminescent material having a small singlet-triplet separation in the emitting layer and a material having an lumo≦−2.55 ev in the adjacent electron-conducting layer.. . ... Merck Patent Gmbh

03/31/16 / #20160090529

Phosphors

The present invention relates to silicate phosphors, to a process for the preparation thereof and to the use thereof as conversion phosphors. The present invention also relates to an emission-converting material comprising at least the conversion phosphor according to the invention, and to the use thereof in light sources, in particular pc-leds (phosphor converted light emitting devices). ... Merck Patent Gmbh

03/31/16 / #20160090399

Removal of fragments from a sample containing a target protein using activated carbon

The present invention provides novel and improved protein purification processes which incorporate certain types of carbonaceous materials and result in effective and selective removal, of protein, fragments without adversely affecting the yield of the desired protein product.. . ... Merck Patent Gmbh

03/24/16 / #20160085108

Device for regulating the passage of energy

The present application relates to a device for regulating the passage of energy which is characterised in that it comprises at least two switching layers s(1) and s(2) arranged one behind the other, where the switching layers comprise a liquid-crystalline medium comprising at least one dichroic compound.. . ... Merck Patent Gmbh

03/24/16 / #20160084784

Device for measuring the conductivity of a liquid in order to determine very low levels of total organic carbon (toc) in pure and ultra-pure water

The present patent application relates to a device (1) for measuring the conductivity of a liquid, which comprises a measuring chamber for containing a sampling volume to be irradiated with uv rays formed in a hydraulic body (4) which comprises an inlet channel for feeding the measuring chamber with liquid to be measured and an outlet channel for removing the measured liquid from the measuring chamber, the inlet channel and the outlet channel emerging on either side beyond a surface exposed to the uv rays, such that only the sampling volume contained in the measuring chamber is irradiated. The present patent application is also directed towards a use of such a device and to a purification system comprising such a device.. ... Merck Patent Gmbh

03/24/16 / #20160083401

Arylquinazolines

The invention relates to novel compounds of the formula (i) which can be used for the inhibition of serine-threonine protein kinases and for the sensitisation of cancer cells to anticancer agents and/or ionising radiation.. . ... Merck Patent Gmbh

03/24/16 / #20160083272

Biocidal purification reactor

A biocidal purification reactor, including a main cylinder tube (1a;1b), at least one end cap (2a,2b,2c) closing at least one axial end opening of the main cylinder tube (1a;1b), at least two ports (3a,3b) communicating with the interior volume (4) of the main cylinder tube (1a;1b) in the vicinity of the respective axial ends of the cylinder tube (1a;1b), and at least one of said end caps (2a) or said main cylinder tube (1b) including a uv-light source (7a;7b).. . ... Merck Patent Gmbh

03/17/16 / #20160077068

Thin-layer chromatography plate, method for producing such a plate, and method for performing a thin-layer chromatography separation

The present invention relates to a thin-layer chromatography plate at least consisting of a support and a sorbent layer, where the sorbent layer comprises at least one siloxane oligomer, to a process for the production thereof, and to a method for carrying out a thin-layer chromatographic separation using said thin-layer chromatography plate.. . ... Merck Patent Gmbh

03/17/16 / #20160075711

Compounds for the inhibition of indoleamine-2,3-dioxygenase

The present invention relates to compounds, and pharmaceutically acceptable compositions thereof, useful as antagonists of ido, and for the treatment of ido-related disorders.. . ... Merck Patent Gmbh

03/10/16 / #20160072076

Materials for electronic devices

The present application relates to a compound of a formula (i) which comprises a benzene group that is substituted with a group selected from carbazole derivatives and bridged amines and with an electron attracting group, wherein the two groups are located in the ortho-position in relation to one another. The present application further relates to the use of the compound of the formula (i) in an electronic device, and to a method of producing the compound of the formula (i).. ... Merck Patent Gmbh

03/10/16 / #20160068755

Layer or article comprising polymer particles

The invention relates to a layer or article comprising cholesteric liquid crystal polymer particles, which are optionally dispersed in a continuous phase, to cholesteric polymer particles for use in such a layer or article, to methods of preparing such a layer or article, and to the use of such a layer or article as optical element, in windows or electrooptical devices like liquid crystal displays (lcds).. . ... Merck Patent Gmbh

03/10/16 / #20160068683

Effect pigments

The present invention relates to effect pigments which are based on flake-form substrates having a circular form factor of 1.2-2 and are coated with at least one high-refractive-index layer, and to the use thereof, inter alia in paints, coatings, printing inks, plastics and in cosmetic formulations.. . ... Merck Patent Gmbh

03/10/16 / #20160067322

Method of treating lung cancer by vaccination with muc-1 lipopeptide

The invention is directed to the treatment of lung cancer, preferably non-small cell lung cancer (nsclc) by means of a combination therapy comprising concurrent chemo-radiotherapy followed by vaccination with a muc-1 lipopetide. The therapy elicits prolonged survival rates compared to a respective therapy including sequential chemo-radiotherapy.. ... Merck Patent Gmbh

03/03/16 / #20160060530

Device containing a liquid-crystalline medium

. . The present invention relates to a temperature-reactive device for the regulation of light transmission, containing a liquid-crystalline medium and a compound of formula i, capable of promoting or inducing homeotropic alignment to the adjacent liquid crystal medium at a given temperature. The invention furthermore relates to a process for the temperature-dependent control of light transmission through a layer of a liquid-crystalline medium.. ... Merck Patent Gmbh

03/03/16 / #20160058763

Novel heterocyclic carboxamides as modulators of kinase activity

The invention provides novel heterocyclic carboxamide compounds according to formula (i) their manufacture and use for the treatment of hyperproliferative diseases, such as cancer.. . ... Merck Patent Gmbh

02/25/16 / #20160054602

Polymerisable compounds and the use thereof in liquid-crystal displays

. . . . The present invention relates to polymerizable compounds, to processes and intermediates for the preparation thereof, to liquid-crystal (lc) media comprising them, and to the use of the polymerizable compounds and lc media for optical, electro-optical and electronic purposes, in particular in lc displays, especially in lc displays of the polymer sustained alignment type.. . ... Merck Patent Gmbh

02/25/16 / #20160053170

Magnesium alumosilicate-based phosphor

The invention relates to co-activated magnesium alumosilicate based phosphors, to a process of its preparation, the use of these phosphors in electronic and electro optical devices, such as light emitting diodes (leds) and solar cells and especially to illumination units comprising said magnesium alumosilicate-based phosphors.. . ... Merck Patent Gmbh

02/18/16 / #20160046866

Devices for high-frequency technology, liquid-crystalline media and compounds

. . The present invention relates to a device for high-frequency technology, or for the microwave region and millimetre wave region of the electromagnetic spectrum, characterised in that it contains a liquid-crystal medium which consists of one or more compounds, which one or more compounds, which contain 6 to 15 five-, six- or seven-membered rings, preferably 1,4-linked phenylene rings, or in that it contains a liquid-crystal medium which itself comprises a component a, which itself consists of one or more of the said compounds, which one or more compounds, which contain 6 to 15 five-, six- or seven-membered rings, preferably 1,4-linked phenylene rings. The present invention additionally relates to compounds of the formula (i), in which the parameters have the meanings given in the text, and to the corresponding, novel liquid-crystal media, to the use and preparation thereof, and to the production and use of the devices. ... Merck Patent Gmbh

02/18/16 / #20160046862

Liquid crystalline medium

The present invention relates to a liquid-crystalline medium based on a mixture of polar compounds having negative dielectric anisotropy (Δ∈), which is distinguished by the fact that it has a value for the ratio γ1/Δn2 in the range 6-45 with a clearing point of >60° c. And a Δ∈ of ≦−2.3. ... Merck Patent Gmbh

02/18/16 / #20160046664

Purification of immunoglobulins from plasma

The present invention relates to the purification of target molecules like immunoglobulins from plasma. The use of a certain type of ion exchanger based on a crosslinked polyvinylether results in especially high yields of the target molecule.. ... Merck Patent Gmbh

02/18/16 / #20160046563

Synthetic building blocks for the production of materials for organic electroluminescence devices

The present invention relates to compounds which are suitable as synthesis precursors for the production of electronically active materials for use in organic electroluminescence devices.. . ... Merck Patent Gmbh

02/11/16 / #20160043332

Materials for organic electroluminescent devices

. . The invention relates to mononuclear neutral copper(i) complexes with a bidentate ligand which is bonded via nitrogen and two phosphine or arsine ligands, to the use thereof for the production of electronic components, and to electronic devices comprising these complexes.. . ... Merck Patent Gmbh

02/04/16 / #20160035992

Organic light-emitting device having delayed fluorescence

. . The present application relates to an organic electroluminescent device (oled) which has an emitting layer comprising a compound having a small difference between the energies of the s1 and t1 states, and in which certain conditions apply to the homo and lumo energy levels of the emitting layer and the layers between the anode and the emitting layer.. . ... Merck Patent Gmbh

02/04/16 / #20160033807

Device for regulating the passage of energy

The present application relates to a device for regulating the passage of light through a light-transmitting area which comprises a switching layer comprising a liquid-crystalline medium comprising at least one dichroic dye, where the parameters degree of light transmission and degree of anisotropy of the device are selected in a certain manner.. . ... Merck Patent Gmbh

02/04/16 / #20160032189

Polymerisable compounds and the use thereof in liquid-crystal displays

The present invention relates to polymerisable compounds, to processes and intermediates for the preparation thereof, to liquid-crystal (lc) media comprising them, and to the use of the polymerisable compounds and lc media for optical, electro-optical and electronic purposes, in particular in lc displays, especially in lc displays of the polymer sustained alignment type.. . ... Merck Patent Gmbh

02/04/16 / #20160031879

Novel indolizine derivatives and their use in neurodegenerative diseases

The present invention relates to indolizine compounds, and pharmaceutically acceptable compositions thereof, useful as antagonists of p2x7, and for the treatment of p2x7-related disorders.. . ... Merck Patent Gmbh

01/28/16 / #20160024119

Electronic device comprising metal complexes

. . The present invention relates to organic electroluminescent devices comprising metal complexes of the formula (1), and to metal complexes for use in organic electroluminescent devices.. . ... Merck Patent Gmbh

01/28/16 / #20160023174

Apparatus for performing sonication

An apparatus for performing sonication on liquid samples comprises a rack for holding an array of sample vials, an ultrasonic probe with an arrangement of recesses corresponding to the array of sample vials and adapted to respectively receive and contact an outer surface of a bottom portion of a respective one of the sample vials, and a counter-holder with an arrangement of pushing members corresponding to the array of sample vials and adapted to respectively apply a force to a respective one of the sample vials so as to push the bottom portion of each vial into contact with the associated recess of the probe. The apparatus can be used in a method of preparing a sample for detection of cell components (e.g. ... Merck Patent Gmbh

01/21/16 / #20160017221

Alumosilicate-based phosphors

. . The invention relates to co-activated silicate based phosphors and a process for preparing these phosphors and the use of these phosphors in electronic and electrooptical devices, especially light emitting diodes (leds) and solar cells. The invention further relates to illumination units comprising said phosphors.. ... Merck Patent Gmbh

01/21/16 / #20160016998

High-affinity matriptase inhibitors

The present invention relates to novel matriptase inhibitors.. . ... Merck Patent Gmbh

01/21/16 / #20160016936

Novel heterocycles as modulators of kinase activity

The invention provides novel heterocyclic amines according to formula (i) their manufacture and use for the treatment of hyperproliferative diseases, such as cancer.. . ... Merck Patent Gmbh

01/14/16 / #20160009824

Tetravalent bispecific antibodies

The present invention relates to tetravalent bispecific antibodies (tetbiabs), methods of making and methods of using the same for diagnostics and for the treatment of cancer or immune disorders. Tetbiabs feature a second pair of fab fragments with a second antigen specificity attached to the c-terminus of an antibody, thus providing a molecule that is bivalent for each of the two antigen specificities. ... Merck Patent Gmbh

01/14/16 / #20160008253

Glucuronolactone derivatives as self-tanning substances

The invention relates to the use of specific glucuronolactone derivatives as self-tanning substances, as tanning enhancers for dihydroxyacetone or for a mixture of self-tanning substances comprising dihydroxyacetone, for modulation of the hue achieved in the case of tanning with dihydroxyacetone or by the mixture or preparation comprising dihydroxyacetone, as contrast-reduction agents or for colouring keratin-containing fibres, and to preparations or compositions for colouring keratin-containing fibres comprising these specific glucuronolactone derivatives.. . ... Merck Patent Gmbh

01/07/16 / #20160001005

Auto-injector for epinephrine injection

. . . . A reloadable auto injector for epinephrine injection is provided. The reloadable auto injector has a separate needle insertion and medicine injection drivers (1600) wherein needle insertion driver (1200) is configured to be re-activated upon reloading. ... Merck Patent Gmbh

01/07/16 / #20160000785

Novel imidazole amines as modulators of kinase activity

The invention provides novel imidazole amine compounds according to formula (i) and formula (ii) their manufacture and use for the treatment of hyperproliferative diseases, such as cancer.. . ... Merck Patent Gmbh








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