Real Time Touch



new TOP 200 Companies filing patents this week

new Companies with the Most Patent Filings (2010+)




Real Time Touch

Merck Patent Gmbh patents (2017 archive)


Recent patent applications related to Merck Patent Gmbh. Merck Patent Gmbh is listed as an Agent/Assignee. Note: Merck Patent Gmbh may have other listings under different names/spellings. We're not affiliated with Merck Patent Gmbh, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "M" | Merck Patent Gmbh-related inventors


Method for doping semiconductors

. . . . The present invention relates to a process for the production of structured, highly efficient solar cells and of photovoltaic elements which have regions of different doping. The invention likewise relates to the solar cells having increased efficiency produced in this way.. ... Merck Patent Gmbh

Optical switching device

An optical switching device comprising a polarisation layer and a switching layer which comprises a liquid-crystalline material and a dye compound. Use of the optical switching device for the regulation of the passage of light through an area element. ... Merck Patent Gmbh

Liquid crystalline medium

The present invention relates to a liquid-crystalline medium based on a mixture of polar compounds having negative dielectric anisotropy (Δε), which is distinguished by the fact that it has a value for the ratio γ1/Δn2 in the range 6-45 with a clearing point of >60° c. And a Δε of ≦−2.3. ... Merck Patent Gmbh

Organic compounds with soluble groups

The present invention relates to soluble organic compounds, to compositions comprising these compounds, to formulations comprising the compounds or compositions, and to electronic devices.. . ... Merck Patent Gmbh

Compositions comprising at least one polymer and at least one metal complex and to electroluminescent devices containing said compositions

. . The present invention relates to compositions comprising at least one polymer which contains triarylamine repeating units, and at least one metal complex, to methods for the production thereof, and the use thereof in electronic devices, especially in organic electroluminescent devices, so-called oleds (oled=organic light emitting diode). The present invention also relates to organic electroluminescent devices which contain said compositions. ... Merck Patent Gmbh

Compositions comprising at least one polymer and at least one salt, and electroluminescent devices containing said compositions

The present invention relates to compositions comprising at least one polymer containing repeat triarylamine units and comprising at least one salt, to processes for production thereof and to the use thereof in electronic devices, especially in organic electroluminescent devices, called oleds (oled=organic light-emitting diodes). The present invention also further relates to organic electroluminescent devices comprising these compositions.. ... Merck Patent Gmbh

Laser doping of semiconductors

The present invention relates to a process for the production of structured, highly efficient solar cells and of photovoltaic elements which have regions of different doping. The invention likewise relates to the solar cells having increased efficiency produced in this way.. ... Merck Patent Gmbh

Compounds having a c-c triple bond

Compounds containing at least one c—c triple bond within a chain of at least 3 ring systems which have positive dielectric anisotropy, the use thereof for high-frequency components, liquid-crystalline media containing these compounds, and high-frequency components, in particular antennae, especially for the gigahertz region, containing these media. The liquid-crystalline media serve, for example, for the phase shifting of microwaves for tuneable phased-array antennae.. ... Merck Patent Gmbh

Organic electroluminescent device

. . The present invention relates to organic electroluminescent devices which comprise mixtures of at least one phosphorescent material and at least two electron-transporting materials.. . ... Merck Patent Gmbh

Compounds for the inhibition of indoleamine-2,3-dioxygenase

The present invention relates to compounds, and pharmaceutically acceptable compositions thereof, useful as antagonists of ido, and for the treatment of ido-related disorders.. . ... Merck Patent Gmbh

Laser-markable and laser-weldable polymeric materials

The present invention relates to laser-markable and laser-weldable polymeric materials which are distinguished by the fact that they comprise, as laser absorber, at least one copper-doped zinc sulfide.. . ... Merck Patent Gmbh

Light modulation element

. . The invention relates to a light modulation element, preferably exploiting the flexoelectric effect comprising a cholesteric liquid crystalline medium sandwiched between two substrates (1), each provided with an electrode structure (2), wherein at least one of the substrates is provided with a photoresist pattern consisting of periodic substantially parallel stripes (3) which is additionally provided with an alignment layer (4). The invention is further related to a method of production of said light modulation element and to the use of said light modulation element in various types of optical and electro-optical devices, such as electro-optical displays, liquid crystal displays (lcds), non-linear optic (nlo) devices, and optical information storage devices.. ... Merck Patent Gmbh

Spectrophotometer and method for carrying out a spectrophotometric measurement

The present invention relates to a spectrophotometer comprising a light source; and a light sensor for measuring the light emitted by the light source and passing through or reflected a sample; and being characterized by an offset generator for applying an offset value to an output of the light sensor. The invention further relates to a method for performing a related spectrophotometric measurement.. ... Merck Patent Gmbh

Fluorine compounds

The present invention relates to compounds of the formula (i) (rf—chf—cf2—chr)m-l-(x)n, where rf=a perfluorinated alkyl group, optionally containing heteroatoms, r=h or an alkyl group, l=a single bond or a divalent organic group, x=an anchor group, m is ≧1 and n is ≧1, and to the use thereof in, for example, dirt-repellent coatings.. . ... Merck Patent Gmbh

12/07/17 / #20170349760

Fluorine compounds

The present invention relates to novel compounds containing fluorinated end groups and to the use thereof in, for example, dirt-repellent coatings.. . ... Merck Patent Gmbh

12/07/17 / #20170349001

Process for the production of a pattern having a three-dimensional appearance in a coating

The present invention relates to a process for the production of a pattern having a three-dimensional appearance in a coating comprising flake-form effect pigments, to a coating produced in this way, and to the use thereof.. . ... Merck Patent Gmbh

12/07/17 / #20170348488

Auto injector with separate needle injection

An auto injector having sequential control of needle insertion and dose injection is disclosed. A syringe with a needle is movably positioned in a housing between a first position in which the needle is accommodated inside the housing and a second position in which the needle protrudes outside the housing. ... Merck Patent Gmbh

12/07/17 / #20170348487

Auto-injector for epinephrine injection

A reloadable auto injector for epinephrine injection is provided. The reloadable auto injector has a separate needle insertion and medicine injection drivers (1600) wherein needle insertion driver (1200) is configured to be re-activated upon reloading. ... Merck Patent Gmbh

12/07/17 / #20170348380

Intraarticular application of pepstatin in the case of arthrosis

The present invention relates to pharmaceutical preparations and medicaments for intraarticular administration, comprising pepstatin, and to the preparation and use thereof, in particular in the treatment and/or prophylaxis of arthrosis, traumatic cartilage injuries, arthritis, pain, allodynia or hyperalgesia, particularly preferably in arthrosis.. . ... Merck Patent Gmbh

11/30/17 / #20170343847

Light modulation element

. . The invention relates to a light modulation element comprising a cholesteric liquid crystalline medium sandwiched between two substrates, each provided with an electrode structure, wherein at least one of the substrates is additionally provided with an alignment layer which is provided with a photoresist pattern consisting of periodic substantially parallel stripes. The invention is further related to a method of production of said light modulation element and to the use of said light modulation element in various types of optical and electro-optical devices, such as electro-optical displays, liquid crystal displays (lcds), non-linear optic (nlo) devices, and optical information storage devices.. ... Merck Patent Gmbh

11/30/17 / #20170343712

A polarized light emissive device

The present invention relates to a polarized light emissive device and a method for its manufacture comprising a plural of fluorescent semiconductor quantum rods, and to a preparation thereof. The invention further relates to a use of the polarized light emissive device in optical devices, and to an optical device comprising the polarized light emissive device.. ... Merck Patent Gmbh

11/30/17 / #20170342372

Cell culture media

The present invention relates to dry cell culture media comprising amino acid components of certain particle size. Some dry powder cell culture media show poor dissolving properties and result in turbid solutions when they are dissolved in aqueous solutions. ... Merck Patent Gmbh

11/30/17 / #20170340989

Target molecule capture from crude solutions

The present invention refers to a method for the separation of peptide aggregates and fragments from solutions containing target peptide.. . ... Merck Patent Gmbh

11/30/17 / #20170340635

Combination of a 6-oxo-1,6-dihydro-pyridazine derivative having anti-cancer activity with a quinazoline derivative

A pharmaceutical composition of 3-(1-{3-[5-(1-methyl-piperidin-4-ylmethoxy)-pyrimidin-2-yl]-benzyl}-6-oxo-1,6-dihydro-pyridazin-3-yl)-benzonitrile or a pharmaceutically acceptable salt and/or solvate thereof in combination with 4-[(s)-2-azetidin-1-yl-1-(4-chloro-3-trifluoromethyl-phenyl)-ethylamino]-quinazoline-8-carboxylic acid amide.. . ... Merck Patent Gmbh

11/23/17 / #20170338414

Materials for organic electroluminescent devices

. . . . The present invention relates to compounds of the formula (1) which are suitable for use in electronic devices, in particular organic electroluminescent devices, and to electronic devices which comprise these compounds.. . ... Merck Patent Gmbh

11/23/17 / #20170336371

Method and device for the optical scanning of a chromatographic sample

A method and device for the optical scanning of a chromatographic sample (3), where a sample plate (2) holding the sample (3) is illuminated with light from a first illumination device (13) and the light emitted by the sample plate (2) is detected by an optical detector device (15) which detects in cell form or area form, a second illumination device (14) is preferably firstly activated in a preparation step. The sample plate (2) is displaced in a first displacement direction relative to the detector device (15), illuminated by the first illumination device (13) and a first measurement image is recorded. ... Merck Patent Gmbh

11/23/17 / #20170335195

Liquid-crystal medium

A liquid-crystalline medium, in particular based on a mixture of polar compounds, having compounds of formulae y, cy, py and/or ly, and compounds of formula s1 and/or s2:. . ... Merck Patent Gmbh

11/23/17 / #20170335194

Liquid-crystal medium

The invention relates to a liquid-crystalline medium, in particular based on a mixture of polar compounds, and to the use thereof for an active-matrix display, in particular based on the va, psa, ps-va, pa-va, palc, ffs, ps-ffs, ips or ps-ips effect.. . ... Merck Patent Gmbh

11/16/17 / #20170331053

Materials for electronic devices

. . The present application relates to a material comprising a monoarylamine of a defined formula and a p-dopant of a defined formula. The present application further relates to the use of said material in an organic layer of an electronic device, the device preferably being an organic electroluminescent device (oled).. ... Merck Patent Gmbh

11/09/17 / #20170324044

Materials for organic electroluminescent devices

The present invention relates to compounds which are suitable for use in electronic devices, and to electronic devices, in particular organic electroluminescent devices, comprising these compounds.. . ... Merck Patent Gmbh

11/09/17 / #20170324038

Heterocyclic compounds for use in electronic devices

The present invention relates to heterocyclic compounds and to electronic devices, especially organic electroluminescent devices, comprising these compounds.. . ... Merck Patent Gmbh

11/09/17 / #20170321186

Process for improving the solubility of cell culture media

The invention relates to a process for improving the solubility of dry cell culture media. Some dry powder cell culture media show poor dissolving properties and result in turbid solutions when they are dissolved in aqueous solutions. ... Merck Patent Gmbh

11/09/17 / #20170321058

Electrically conductive, colored interference pigments

The present invention relates to electrically conductive, coloured interference pigments, in particular flake-form interference pigments, which have an outermost layer which comprises crystalline carbon in the form of graphite and/or graphene, to a process for the preparation of such pigments, and to the use of the pigments prepared in this way.. . ... Merck Patent Gmbh

11/09/17 / #20170321057

Non-metallic pigments having metal properties

The present invention relates to non-metallic interference pigments, in particular laminar interference pigments, which comprise a thin high-refractive layer and an outermost layer that contains crystalline carbon in the form of graphite and/or graphene. The invention also relates to a method for producing such pigments and the use of the thus produced pigments.. ... Merck Patent Gmbh

11/09/17 / #20170320873

Method for the production of praziquantel and precursors thereof

The present invention relates to methods for the production of enantiopure or enantioenriched praziquantel precursors and to methods for the production of enantiopure or enantioenriched praziquantel comprising the methods for the production of the praziquantel precursors. The present invention further relates to compounds or intermediates useful in such methods.. ... Merck Patent Gmbh

11/09/17 / #20170319581

Combination of a 6-oxo-1,6-dihydro-pyridazine derivative having anti-cancer activity with an egfr inhibitor

A pharmaceutical composition of 3-(1-{3-[5-(1-methyl-piperidin-4-ylmethoxy)-pyrimidin-2-yl]-benzyl}-6-oxo-1,6-dihydro-pyridazin-3-yl)-benzonitrile or a pharmaceutically acceptable salt and/or solvate thereof in combination with n-[3-[[2-[4-(4-acetylpiperazin-1-yl)-2-methoxy-anilino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]phenyl]prop-2-enamide.. . ... Merck Patent Gmbh

10/26/17 / #20170309855

Organic electroluminescence device

The present invention relates to organic electroluminescent devices which comprise a mixture of at least two materials in the electron-transport layer.. . ... Merck Patent Gmbh

10/26/17 / #20170309848

Semiconductor composition comprising an inorganic semiconducting material and an organic binder

The present invention relates to a semiconductor composition comprising an inorganic semiconducting material and an organic binder. The present invention further relates to an electronic device comprising a semiconducting layer consisting of such semiconductor composition.. ... Merck Patent Gmbh

10/26/17 / #20170309834

Materials for electronic devices

The present invention relates to an electronic device comprising anode, cathode and at least one organic layer which comprises a compound of the formula (i) to (iv). The invention furthermore encompasses the use of compounds of the formula (i) to (iv) in an electronic device and to a compound of the formula (ic) to (ivc).. ... Merck Patent Gmbh

10/26/17 / #20170309832

Metal complexes

The present invention relates to metal complexes and to electronic devices, in particular organic electroluminescent devices, comprising these metal complexes.. . ... Merck Patent Gmbh

10/26/17 / #20170307939

Lc-based optical display system

An optically active structure and a display device are presented. The device utilized an optically active structure comprising liquid crystal material and a plurality of nanorods configured to emit light in one or more predetermined ranges in response to pumping light. ... Merck Patent Gmbh

10/26/17 / #20170306232

Liquid-crystalline medium

The invention relates to a liquid-crystalline medium and to the use thereof for an active-matrix display, in particular based on the va, psa, ps-va, pm-va, ss-va, palc, ips, ps-ips, ffs or ps-ffs effect.. . ... Merck Patent Gmbh

10/26/17 / #20170306230

Liquid-crystalline medium and high-frequency components comprising same

The present invention relates to liquid-crystalline media comprising—one or more compounds of formulae cc and/or cp and—one or more compounds selected from the group of compounds of formulae (i), (ii) and (iii), in which the parameters have the meaning indicated in claim 1, and to components comprising these media for high-frequency technology, in particular phase shifters and microwave array antennas.. . ... Merck Patent Gmbh

10/26/17 / #20170306223

Phosphors

The present invention relates to europium-, cerium-, samarium- or praseodymium-doped boronitrides, to a process for the preparation of these compounds, and to the use of the doped boronitrides according to the invention as conversion phosphors. The present invention furthermore relates to a light source which contains a doped boronitride according to the invention.. ... Merck Patent Gmbh

10/26/17 / #20170304246

Solid pharmaceutical preparation containing levothyroxine

The invention relates to a solid pharmaceutical preparation comprising levothyroxine sodium, gelatine, citric acid and a filler. The solid pharmaceutical preparation has an improved stability.. ... Merck Patent Gmbh

10/26/17 / #20170304168

Phenyl ketone derivatives as self-tanning agents

The present invention relates to the use of phenyl ketone derivatives of the formula i for use as self-tanning substance or for increasing melanin synthesis, improving melanin transport and/or improving the distribution of melanin in suprabasal layers, and to preparations comprising these phenyl ketone derivatives.. . ... Merck Patent Gmbh

10/12/17 / #20170294585

Fullerene mixtures for use in organic electronic devices

. . . . The invention relates to novel mixtures of substituted fullerenes, to their use in organic electronic (oe) devices, especially organic photovoltaic (opv) devices and organic photodetectors (opd), and to oe, opv and opd devices comprising these fullerene mixtures.. . ... Merck Patent Gmbh

10/12/17 / #20170294582

Formulations and electronic devices

The present invention relates to a formulation comprising at least one organofunctional material which can be employed for the production of functional layers of electronic devices, and at least one aromatic compound. The present invention furthermore relates to electronic devices which are obtainable from these formulations.. ... Merck Patent Gmbh

10/12/17 / #20170291919

Soluble intein fusion proteins and methods for purifying biomolecules

The present invention relates to fusion proteins comprising an n-intein polypeptide and an n-intein solubilization partner, and affinity chromatography matrices comprising such fusion proteins, as well as methods of using same.. . ... Merck Patent Gmbh

10/12/17 / #20170290836

Arylquinazolines

The invention relates to novel compounds of the formula (i) which can be used for the inhibition of serine-threonine protein kinases and for the sensitisation of cancer cells to anticancer agents and/or ionising radiation.. . ... Merck Patent Gmbh

10/05/17 / #20170283699

Reactive mesogen formulation with conductive additive

The invention relates to a reactive mesogen (rm) formulation comprising a conductive additive, to a polymer film obtained thereof, and the use of the rm formulation and polymer film in optical or electrooptical components or devices, like optical retardation films for liquid crystal displays (lcds).. . ... Merck Patent Gmbh

10/05/17 / #20170283427

Compounds for the inhibition of cyclophilins and uses thereof

The present invention relates to compounds, and pharmaceutically acceptable compositions thereof, useful as inhibitors of cyclophilins, and for the treatment of cyclophilin-related disorders.. . ... Merck Patent Gmbh

10/05/17 / #20170283426

Compounds for the inhibition of cyclophilins and uses thereof

The present invention relates to compounds, and pharmaceutically acceptable compositions thereof, useful as inhibitors of cyclophilins, and for the treatment of cyclophilin-related disorders.. . ... Merck Patent Gmbh

10/05/17 / #20170283425

Compounds for the inhibition of cyclophilins and uses thereof

The present invention relates to compounds, and pharmaceutically acceptable compositions thereof, useful as inhibitors of cyclophilins, and for the treatment of cyclophilin-related disorders.. . ... Merck Patent Gmbh

09/28/17 / #20170279048

Diazirine containing organic electronic compositions and device thereof

The present invention relates to organic electronic devices, and more specifically to organic field effect transistors, comprising a dielectric layer that comprises a polycycloolefinic polymer and a diazirine compound.. . ... Merck Patent Gmbh

09/28/17 / #20170275284

Macrocyclic compounds as irak1/4 inhibitors and uses thereof

The present invention relates to compounds of formula i and pharmaceutically acceptable compositions thereof, useful as irak inhibitors.. . ... Merck Patent Gmbh

09/21/17 / #20170267929

Device for regulating the passage of energy

The present application relates to a device for regulating the passage of energy from an outside space into an inside space, to compounds, windows and uses of the devices and compounds.. . ... Merck Patent Gmbh

09/21/17 / #20170267928

Liquid crystalline medium

The present invention relates to a liquid-crystalline medium based on a mixture of polar compounds having negative dielectric anisotropy (Δ∈), which is distinguished by the fact that it has a value for the ratio γ1/Δn2 in the range 6-45 with a clearing point of >60° c. And a Δ∈ of ≦−2.3. ... Merck Patent Gmbh

09/14/17 / #20170260562

Petri dish and method for the microbiological examination of liquids by membrane filtration

The invention relates to a medium-filled petri dish into which filters can be introduced particularly simply, and to a method for the microbiological investigation of liquids or gases by means of filtration and incubation of the filters in said petri dishes.. . ... Merck Patent Gmbh

09/07/17 / #20170256728

Conjugated polymers

The invention relates to novel conjugated polymers containing one or more 5,6-difluoro-benzo[1,2,5]thiadiazole-4,7-diylunits (hereinafter referred to as “ff-btz” units) and two or more different bridged bithiophene units, to methods for their preparation and educts or intermediates used therein, to polymer blends, mixtures and formulations containing them, to the use of the polymers, polymer blends, mixtures and formulations as organic semiconductors in, or for the preparation of, organic electronic (oe) devices, especially organic photovoltaic (opv) devices and organic photodetectors (opd), and to oe, opv and opd devices comprising, or being prepared from, these polymers, polymer blends, mixtures or formulations.. . ... Merck Patent Gmbh

09/07/17 / #20170253801

Liquid-crystal media and light modulation element

The present invention relates to liquid crystalline (lc) medium, to a method of its production and to the use of such lc media in polymer network liquid crystalline (pnlc) light modulation elements operated in the reverse mode. Furthermore, the present invention relates to such light modulation elements, as such, to the use of such light modulation elements as light shutters for transparent oled displays, and to a method of production of such light modulation elements according to the present invention.. ... Merck Patent Gmbh

09/07/17 / #20170253654

Anti-pd-l1 antibodies and uses thereof

The present application relates to anti-pd-l1 antibodies or antigen binding fragments thereof, nucleic acid encoding the same, therapeutic compositions thereof, and their use to enhance t-cell function to upregulate cell-mediated immune responses and for the treatment of t cell dysfunctional disorders, such as tumor immunity, for the treatment of and cancer.. . ... Merck Patent Gmbh

09/07/17 / #20170253653

Anti-pd-l1 antibodies and uses thereof

The present application relates to anti-pd-l1 antibodies or antigen binding fragments thereof, nucleic acid encoding the same, therapeutic compositions thereof, and their use to enhance t-cell function to upregulate cell-mediated immune responses and for the treatment of t cell dysfunctional disorders, such as tumor immunity, for the treatment of and cancer.. . ... Merck Patent Gmbh

08/31/17 / #20170250353

Metal complexes

The present invention relates to metal complexes and to electronic devices, in particular organic electroluminescent devices, comprising these metal complexes.. . ... Merck Patent Gmbh

08/31/17 / #20170246317

Dna sequence, and recombinant preparation of group 4 major allergens from cereals

The present invention relates to the provision of dna sequences of group 4 mayor allergens from cereals. The invention also encompasses fragments, new combinations of partial sequences and point mutants having a hypoallergenic action. ... Merck Patent Gmbh

08/24/17 / #20170240812

Substituted polyphenyls

The invention relates to substituted quinquephenyls of the formulae indicated in the claims and description. They are particularly suitable as uv-stabilising component in liquid-crystalline media.. ... Merck Patent Gmbh

08/24/17 / #20170240745

Effect pigments

Effect pigments based on al2o3 flakes with high weather resistance and less photoactivity and to their use thereof in paints, industrial coatings, automotive coatings, printing inks, cosmetic formulations. The effect pigments have a ratio of the amount by weight of al2o3 of the al2o3 flake and the amount by weight of the metal oxide(s) of the coating layer(s) in the range of from 27:73 to 83:17 based on the total weight of the effect pigment.. ... Merck Patent Gmbh

08/24/17 / #20170240574

Alkenyl (perfluoroalkyl) phosphinic acids

The invention relates to alkenyl(perfluoroalkyl)phosphinic acids, to the preparation and intermediates thereof, to the use thereof as monomers for the preparation of oligomers and/or polymers, to the corresponding oligomers/polymers, to the corresponding support materials comprising the oligomers/polymers, and to the use thereof as ion exchangers, as catalysts or extraction medium and corresponding salts thereof.. . ... Merck Patent Gmbh

08/17/17 / #20170237017

Materials for organic electroluminescent devices

. . The present invention relates to electron-deficient heteroaromatic compounds which are substituted by dibenzofuran or dibenzothiophene derivatives and by carbazoles or amines, in particular for use as triplet matrix materials in organic electroluminescent devices. The invention furthermore relates to a process for the preparation of the compounds according to the invention and to electronic devices comprising these compounds.. ... Merck Patent Gmbh

08/17/17 / #20170233495

Antibodies specific for mmp9

The present invention relates to new proteins that bind to mmp9 and comprise at least one fragment of a heavy chain variable region and/or at least one fragment of a light chain variable region of an antibody. In particular, the mmp9 binding proteins according to the invention are able to neutralize mmp9 activity and are useful in the prevention and/or treatment of inflammatory and/or autoimmune diseases or cancers. ... Merck Patent Gmbh

08/17/17 / #20170233377

Heterocyclic compounds as nav channel inhibitors and uses thereof

The present invention relates to heterocyclic compounds, and pharmaceutically acceptable compositions thereof, useful as nav1.6 inhibitors.. . ... Merck Patent Gmbh

08/10/17 / #20170226422

Polymerisable mesogenic compound, liquid crystal medium and liquid crystal display

. . The present invention relates to liquid crystal media comprising polymerisable mesogenic compounds with a bent shape, and to electro-optical displays comprising these media as light modulation media. In particular the electro-optical displays according to the present invention are displays, which are operated at a temperature, at which the liquid crystal modulation media are in an optically isotropic phase, preferably in a blue phase.. ... Merck Patent Gmbh

08/10/17 / #20170226421

Polymerisable lc medium and polymer film with negative optical dispersion

The invention relates to a polymerisable lc medium with negative optical dispersion, a polymer film with negative optical dispersion obtainable from such a medium, and the use of the polymerisable lc medium and polymer film in optical, electro optical, electronic, semiconducting or luminescent components or devices.. . ... Merck Patent Gmbh

08/10/17 / #20170226199

Anti-tnf alpha antibodies with ph-dependend antigen binding for improved target clearence

The invention relates to anti-tnfa antibodies which are engineered to exhibit a ph-sensitive antigen binding. The invention is preferably directed to anti-tnfa antibody adalimumab (humira®) or biologically active variants and fragments thereof, wherein the original adalimumab antibody or variant or fragment thereof is engineered by modifications of amino acid sequence within the variable regions. ... Merck Patent Gmbh

08/10/17 / #20170226113

Pyridines, pyrimidines, and pyrazines, as btk inhibitors and uses thereof

The present invention relates to pyridine, pyrimidine, and pyrazene compounds, and pharmaceutically acceptable compositions thereof, useful as btk inhibitors.. . ... Merck Patent Gmbh

08/10/17 / #20170226080

Pyrrolidinone derivatives as metap-2 inhibitors

Compounds according to claim 1, are inhibitors of methionine aminopeptidase and can be employed for the treatment of tumours.. . ... Merck Patent Gmbh

08/10/17 / #20170224860

Sample preparation container

A sample preparation container, preferably for use in sterility testing, comprising a housing (1) having a housing wall (2) defining an inside space (3), a support on which a membrane filter is placed or is to be placed so as to get in contact with a sampling fluid to be introduced into the inside space (3), and at least one inlet opening (4) to the inside space (3) and at least one outlet opening from the inside space (3). A sampling port (5) is provided for allowing access from the outside to the inside space (3), wherein said sampling port (5) is closed by a septum (6) and the septum (6) is separated from the inside space (3) by a barrier wall (7) which is preferably piercable or breakable on application of an external force, preferably applied through a sampling instrument like a needle (8).. ... Merck Patent Gmbh

08/03/17 / #20170222157

Materials for electronic devices

The present invention relates to compounds, compositions and formulations comprising same and to opto-electronic devices comprising the compounds and compositions according to the invention.. . ... Merck Patent Gmbh

08/03/17 / #20170218070

Anti-alpha-v integrin antibody for the treatment of prostate cancer

The invention is directed to the treatment of prostate cancer by means of antibodies. Above all, the invention relates to the administration of an anti-alpha-v integrin (receptor) antibody to patients suffering from prostate cancer, especially castration-resistant prostate cancer (crpc), optionally accompanied by lymph node and bone tissue metastases (mcrpc). ... Merck Patent Gmbh

08/03/17 / #20170217905

Aminopyrimidine derivatives for use as modulators of kinase activity

The invention provides novel heterocyclic amine compounds according to formula (i) and their manufacture and use for the treatment of hyperproliferative diseases, such as cancer.. . ... Merck Patent Gmbh

08/03/17 / #20170217863

Fluorinated tensides

The present invention relates to novel compounds containing fluorinated end groups, to the use thereof as surface-active substances, and to compositions comprising these compounds.. . ... Merck Patent Gmbh

08/03/17 / #20170216213

Directly compressible polyvinyl alcohols

The present invention relates to directly compressible co-mixtures for the production of tablets having delayed release of active compound which comprise polyvinyl alcohols (pvas) and microcrystalline celluloses (mccs). The invention also relates to a process for the preparation of corresponding directly compressible co-mixture. ... Merck Patent Gmbh

07/27/17 / #20170211567

Rotor device for peristaltic pump

. . The invention relates to a rotor device for a peristaltic pump comprising a housing, a supporting shaft extending in an axial direction and being mounted in the housing, a rotor comprising a rotor-body mounted on the supporting shaft and extending in a radial direction from the supporting shaft and a plurality of rollers, mounted on the radially outer portion of the rotor-body and a driving device connected to the supporting shaft for driving the rotor, wherein the peristaltic pump further comprises a number of roller-markers corresponding to the number of rollers, wherein the roller-markers indicate a dead zone, the roller-markers are provided directly or indirectly on the supporting shaft.. . ... Merck Patent Gmbh

07/27/17 / #20170210905

Colored effect pigments

The present invention relates to colored effect pigments, in particular to those containing an organic color pigment layer, to a preparation method thereof and to the use of these pigments especially in a composition comprising the colored effect pigments.. . ... Merck Patent Gmbh

07/27/17 / #20170210817

Anti-cancer antibodies with reduced complement fixation

The invention provides modified antibodies directed against gd2 that have diminished complement fixation relative to antibody-dependent, cell-mediated cytotoxicity, which is maintained. The modified antibodies of the invention may be used in the treatment of tumors such as neuroblastoma, glioblastoma, melanoma, small-cell lung carcinoma, b-cell lymphoma, renal carcinoma, retinoblastoma, and other cancers of neuroectodermal origin.. ... Merck Patent Gmbh

07/27/17 / #20170210752

Tetra-heteroaryl indacenodithiophene-based polycyclic polymers and their use

The present invention relates compounds comprising a tetra-heteroaryl indacenodithiophene-based structural unit, the synthesis of such compounds as well as their use in organic electronic devices. The invention further relates to organic electronic devices comprising such compounds.. ... Merck Patent Gmbh

07/27/17 / #20170209380

Directly compressible composition comprising microcrystalline cellulose

The present invention relates to a directly compressible composition for the production of tablets which comprise fine-grained polyvinyl alcohols (pvas) and fine-grained microcrystalline celluloses (mccs) in a co-mixture. The present invention also relates to the use of this mixture and to a process for the preparation thereof.. ... Merck Patent Gmbh

07/20/17 / #20170207399

Materials for organic electroluminescent devices

. . The present invention describes dibenzofuran and dibenzothiophene derivatives, in particular for use as triplet matrix materials in organic electroluminescent devices. The invention furthermore relates to a process for the preparation of the compounds according to the invention and to electronic devices comprising same.. ... Merck Patent Gmbh

07/06/17 / #20170189354

Pharmaceutical composition comprising rimeporide for treating diseases associated with insulin resistance and beta-cell dysfunction

. . The invention relates to a pharmaceutical composition comprising as active ingredient an effective amount of 2-methyl-4,5-di-(methylsulfonyl)-benzoyl-guanidine, or derivatives thereof, for the prophylaxis and therapy of type ii diabetes mellitus, the metabolic syndrome, diabetic nephropathy and/or neuropathy. Another object of the invention concerns the use of 2-methyl-4,5-di-(methylsulfonyl)-benzoyl-guanidine, or derivatives thereof, for the enhancement of insulin sensitivity and the preservation or increase of β-cell compensation.. ... Merck Patent Gmbh

07/06/17 / #20170189338

Tableting agent having a low water content, and method for the production thereof

The present invention relates to a tabletting aid with a low water content and to a process for the preparation thereof. The tabletting aid composition is a directly compressible composition, the use of which results in improved tablet properties.. ... Merck Patent Gmbh

06/29/17 / #20170186965

Materials for organic light emitting devices

The present invention describes carbazole, dibenzofuran, dibenzothiophene and fluorene derivatives which are substituted by electron-deficient heteroaryl groups, in particular for use as triplet matrix materials in organic electroluminescent devices. The invention furthermore relates to a process for the preparation of the compounds according to the invention and to electronic devices comprising these compounds.. ... Merck Patent Gmbh

06/29/17 / #20170182333

Enhancement of penetration and action

The present invention relates, inter alia, to dermal systems comprising at least one light source and at least one pharmaceutically and/or cosmetically active ingredient. The dermal systems can be employed in order to enhance the penetration and action of the pharmaceutically and/or cosmetically active ingredient.. ... Merck Patent Gmbh

06/29/17 / #20170182037

Polymorphic forms of 1-[4-(5-cyanoindol-3-yl)butyl]-4-(2-carbamoylbenzofuran-5-yl) piperazine hydrochloride

The invention relates to new crystalline modifications of the hydrochloride of 1-[4-(5-cyanoindol-3-yl)butyl]-4-(2-carbamoyl-benzofuran-5-yl)-piperazine, crystalline modification of the dihydrochloride of 1-[4-(5-cyanoindol-3-yl)butyl]-4-(2-carbamoyl-benzofuran-5-yl)-piperazine and amorphous 1-[4-(5-cyanoindol-3-yl)butyl]-4-(2-carbamoyl-benzofuran-5-yl)-piperazine hydrochloride which are suitable in particular for the preparation of solid medicaments for the treatment or prevention of depressive disorders, anxiety disorders, bipolar disorders, mania, dementia, substance-related disorders, sexual dysfunctions, eating disorders, obesity, fibromyalgia, sleeping disorders, psychiatric disorders, cerebral infarct, tension, for the therapy of side-effects in the treatment of hypertension, cerebral disorders, chronic pain, acromegaly, hypogonadism, secondary amenorrhea, premenstrual syndrome and undesired puerperal lactation.. . ... Merck Patent Gmbh

06/22/17 / #20170179399

Compounds for electronic devices

The present invention relates to a compound of the formula (i), to the use of this compound in an electronic device, and to an electronic device comprising one or more compounds of the formula (i). The invention furthermore relates to the preparation of the compound of the formula (i) and to a formulation comprising one or more compounds of the formula (i).. ... Merck Patent Gmbh

06/22/17 / #20170179392

White light emission

The present invention relates inter alia to compositions comprising conjugated polymers and a small molecule, devices comprising the composition and the application of the devices.. . ... Merck Patent Gmbh

06/22/17 / #20170174653

Tlr7/8 antagonists and uses thereof

The present invention relates to compounds of formula i and pharmaceutically acceptable compositions thereof, useful as tlr7/8 antagonists.. . ... Merck Patent Gmbh

06/22/17 / #20170173019

Pyridazinone macrocycles as irak inhibitors and uses thereof

The present invention relates to compounds of formula i and pharmaceutically acceptable compositions thereof, useful as irak inhibitors.. . ... Merck Patent Gmbh

06/15/17 / #20170170413

Metal complexes

The present invention relates to metal complexes and to electronic devices, in particular organic electroluminescent devices, comprising these metal complexes.. . ... Merck Patent Gmbh

06/15/17 / #20170170345

Method for producing a uv photodetector

This invention relates to a method for producing a photodetector based on the deposition of precursor system having a liquid phase. The photodetectors are characterized by a certain group of semiconductor materials which can be used as the absorber in solar-blind uv detectors. ... Merck Patent Gmbh

06/15/17 / #20170166620

Cancer-targeted il-12 immunotherapy

The invention is directed to cancer immunotherapy. The invention is specifically directed to the induction of innate or adaptive antitumor immunity initiated by the administration of targeted il-12 molecules preferably in conjunction with il-2 and/or il-7 to a cancer patient, who suffers from cancer of the muscle, bone, nerves, cartilage, tendons, blood vessels, etc., preferably from sarcoma. ... Merck Patent Gmbh

06/15/17 / #20170166567

Imidazo[4,5-c]quinolines as dna-pk inhibitors

The invention relates to compounds of the formulae (i) and (ii) in which r1, r2, r3, r4, r5, r8, x and m have the meaning indicated in the claims, and/or physiologically acceptable salts, tautomers and stereoisomers thereof, including mixtures thereof in all ratios. The compounds of the formula (i) can be used for the inhibition of serine/threonine protein kinases and for the sensitisation of cancer cells to anticancer agents and/or ionising radiation. ... Merck Patent Gmbh

06/08/17 / #20170162805

Extended non-linear acene derivatives and their use as organic semiconductors

The invention relates to extended non-linear acene derivatives, methods of their preparation, their use as semiconductors in organic electronic (oe) devices, and oe devices comprising them.. . ... Merck Patent Gmbh

06/08/17 / #20170157966

Rotary printing method

The present invention relates to a rotary printing process for the application of functional coatings to a print substrate, to a coated print substrate produced by the said process, and to the use thereof, in particular in the packaging sector.. . ... Merck Patent Gmbh

06/01/17 / #20170155062

Compounds for electronic devices

The present invention relates to compounds of the formula (1) or (2) and to the use thereof in electronic devices, and to electronic devices which comprise these compounds. The invention furthermore relates to the preparation of the compounds of the formula (1) or (2) and to formulations comprising one or more compounds of the formula (1) or (2).. ... Merck Patent Gmbh

06/01/17 / #20170152372

Microspheres

The present invention relates to microspheres and to the use thereof, preferably as laser-absorbing additive, and to a process for the production thereof.. . ... Merck Patent Gmbh

05/18/17 / #20170141329

Metal complexes

. . The invention relates to metal complexes and to electronic devices, in particular organic electroluminescence devices, containing said metal complexes.. . ... Merck Patent Gmbh

05/18/17 / #20170141328

Compositions for electronic devices

The present invention relates to compositions and formulations for electronic devices comprising mixtures of organic functional materials.. . ... Merck Patent Gmbh

05/18/17 / #20170141327

Materials for organic electroluminescent devices

The invention relates to compounds which are suitable for use in electronic devices, and to electronic devices, in particular organic electroluminescent devices, containing said compounds.. . ... Merck Patent Gmbh

05/18/17 / #20170141317

Tetra-aryl indacenodithiophene-based polycyclic polymers and their use

The present invention relates to compounds comprising a tetra-aryl indacenodithiophene-based structural unit, the synthesis of such compounds as well as their use in organic electronic devices. The invention further relates to organic electronic devices comprising such compounds.. ... Merck Patent Gmbh

05/18/17 / #20170137611

Additive for lds plastics

The present invention relates to an lds-active additive for lds plastics, to a polymer composition comprising an additive of this type, and to an article having metallised conductor tracks in which a polymeric basic body of the article or a polymeric coating on a basic body comprises an lds additive of the said type.. . ... Merck Patent Gmbh

05/18/17 / #20170137428

Azepanyl-derivatives and pharmaceutical compositions comprising the same with antiparasitic activity

The present invention provides compounds of formula (i). Furthermore, pharmaceutical compositions are provided comprising at least one compound of formula (i), for the treatment of parasitic diseases including malaria, as well as neurodegenerative diseases.. ... Merck Patent Gmbh

05/18/17 / #20170136048

Compositions and methods for the production of pyrimidine and pyridine compounds with btk inhibitory activity

The present invention provides novel pyrimidine and pyridine compounds according to formula (i), formula (ii), formula (iii), formula (iv) and formula (v) their manufacture and use for the treatment of hyperproliferative diseases including, but not limited to, cancer, lupus, allergic disorders, sjogren's disease and rheumatoid arthritis. In preferred embodiments, the present invention describes irreversible kinase inhibitors including, but not limited to, inhibitors of bruton's tyrosine kinase.. ... Merck Patent Gmbh

05/18/17 / #20170136018

Methods for treating ms using pyrimidine and pyridine compounds with btk inhibitory activity

The present invention provides methods of treating ms using pyrimidine and pyridine compounds which are inhibitors of bruton's tyrosine kinase (btk).. . ... Merck Patent Gmbh

05/11/17 / #20170130054

Effect pigments

. . The present invention relates to silver-coloured effect pigments having a strong sparkle effect based on al2o3 flakes and to the use thereof in paints, button pastes, automotive paints, automotive refinish paints, powder coatings, printing inks, security printing inks, plastics, ceramic materials, glasses, paper, for coating seed, in security applications, as dopant for the laser marking of plastics and papers, as additive for the laser welding of plastics, in cosmetic formulations and for the preparation of pigment preparations and dry preparations.. . ... Merck Patent Gmbh

05/11/17 / #20170129877

Cyclic amine azaheterocyclic carboxamides

The invention provides novel cyclic amine azaheterocyclic carboxamide according to formula (i), formula (ii) and formula (iii) their manufacture and use for the treatment of hyperproliferative diseases, such as cancer.. . ... Merck Patent Gmbh

05/04/17 / #20170125701

Materials for electronic devices

. . The present application relates to heterospirobifluorene compounds, to a process for the preparation thereof, and to electronic devices, in particular organic electroluminescent devices, comprising the heterospirobifluorene derivatives.. . ... Merck Patent Gmbh

05/04/17 / #20170125686

Materials for electronic devices

The present application relates to a substituted benzanthracene compound of a formula (i) or (ii). The application furthermore relates to an electronic device which comprises the said benzanthracene compound.. ... Merck Patent Gmbh

05/04/17 / #20170125676

Formulations for the production of electronic devices

The present invention relates to a formula, comprising at least one solvent, and at least one functional composition of the general formula (i), wherein a is a functional structural element, b is a solvent-providing structural element, and k is an integer in the range of 1 to 20. The molecular weight of the functional composition is at least 550 g/mol, and the solvent-providing structural element b corresponds to the general formula ((l-i). ... Merck Patent Gmbh

05/04/17 / #20170123275

Liquid-crystal display device and process for producing liquid-crystal display device

The present invention provides a liquid-crystal display device capable of maintaining a high voltage holding ratio even without an alignment film. The liquid-crystal display device of the present invention includes a pair of substrates, a liquid crystal layer which is sandwiched between the substrates and which contains a liquid crystal material, and a polymer layer which is disposed on a surface of each of the substrates and which controls the alignment of liquid crystal molecules. ... Merck Patent Gmbh

05/04/17 / #20170121606

Polymerizable compounds and the use thereof in liquid-crystal displays

The present invention relates to polymerizable compounds, to processes and intermediates for the preparation thereof, to liquid-crystal (lc) media comprising them, and to the use of the polymerizable compounds and lc media for optical, electro-optical and electronic purposes, in particular in lc displays, especially in lc displays of the polymer sustained alignment type, or a stabilizers in lc media and lc displays.. . ... Merck Patent Gmbh

05/04/17 / #20170121260

Fluorinated tensides

The present invention relates to novel compounds containing fluorinated end groups, to the use thereof as surface-active substances, and to compositions comprising these compounds.. . ... Merck Patent Gmbh

05/04/17 / #20170119766

Methods for treating cancer using pyrimidine and pyridine compounds with btk inhibitory activity

The present invention provides methods of treating cancer using pyrimidine and pyridine compounds which are inhibitors of bruton's tyrosine kinase (btk).. . ... Merck Patent Gmbh

04/27/17 / #20170117477

Organic semiconducting compounds

The invention relates to novel organic semiconducting compounds, which are small molecules or conjugated polymers, containing one or more fluorinated polycyclic units, to methods for their preparation and educts or intermediates used therein, to compositions, polymer blends and formulations containing them, to the use of the compounds, compositions and polymer blends as organic semiconductors in, or for the preparation of, organic electronic (oe) devices, especially organic photovoltaic (opv) devices, organic photodetectors (opd), organic field effect transistors (ofet) and organic light emitting diodes (oled), and to oe, opv, opd, ofet and oled devices comprising these compounds, compositions or polymer blends.. . ... Merck Patent Gmbh

04/27/17 / #20170115439

A polarized light emissive device

The present invention relates to a polarized light emissive device comprising a plural of fluorescent semiconductor quantum rods, and to a preparation thereof. The invention further relates to a use of the polarized light emissive device in optical devices, and to an optical device comprising the polarized light emissive device.. ... Merck Patent Gmbh

04/20/17 / #20170107426

Europium- or samarium-doped terbium molybdates

The invention relates to europium or samarium-doped terbium molybdates, to a method for producing said compounds, and to the use of the claimed europium or samarium-doped terbium molybdates as conversion lumiophores. The invention also relates to a light-emitting device containing a claimed europium or samarium-doped terbium molybdate.. ... Merck Patent Gmbh

04/20/17 / #20170107379

Pigment/frit mixtures

Frits or frit mixtures with pearlescent pigments for materials, such as ceramic glazes, which are stable above 1000° c.. . ... Merck Patent Gmbh

04/20/17 / #20170105915

Alpha-al2o3 flakes

The present invention relates to α-al2o3 flakes prepared by a process comprising (1) preparation of an aqueous solution of at least one water-soluble and/or insoluble aluminum salt which optionally contains at least one sulfate compound, (2) adding a basic solution and optionally at least one dopant to the aluminum salt solution (1), (3) drying of the obtained gel, followed by calcination to obtain al2 03 flakes and alkali salts in a molten salt, and (4) removal of the water soluble parts of the calcined molten salt obtained in step (3).. . ... Merck Patent Gmbh

04/13/17 / #20170104165

Materials for electronic devices

The present invention relates to compounds of the formula (i), to the use of compounds of the formula (i) in electronic devices and electronic devices comprising one or more compounds of the formula (i). The invention furthermore relates to the preparation of the compounds of the formula (i) and to formulations comprising one or more compounds of the formula (i).. ... Merck Patent Gmbh

04/13/17 / #20170101523

Laser-markable and laser-weldable polymeric materials

The present invention relates to laser-markable and laser-weldable polymeric materials which are distinguished by the fact that they comprise at least one fluorine-doped tin oxide (fto) as absorber.. . ... Merck Patent Gmbh

04/13/17 / #20170100607

Fibers in therapy and cosmetics

The present invention relates inter alia to functional materials for the treatment and/or prophylaxis and/or diagnosis of diseases and/or cosmetic conditions. The functional materials can be used for the preparation of light emitting devices comprising fibers as light emitting elements.. ... Merck Patent Gmbh

04/13/17 / #20170100402

Combinations of cancer therapeutics

The invention relates to combinations of 4-[(s)-2-azetidin-1-yl-1-(4-chloro-3-trifluoromethyl-phenyl)-ethylamino]-quinazoline-8-carboxylic acid amide and/or its physiologically acceptable salts and solvates, and an inhibitor of her2, and the use of such combinations for the treatment of cancer.. . ... Merck Patent Gmbh

04/06/17 / #20170098775

Fullerene derivatives, and related materials, methods and devices

The invention relates to improved fullerene derivatives, to methods for their synthesis and any educts or intermediates used in such methods, to compositions and formulations containing fullerene derivatives, to the use of the fullerene derivatives, compositions and formulations in, or for the preparation of, organic electronic (oe) devices like for example organic photovoltaic (opv) devices or organic photodetectors (opd), and to oe, opv and opd devices comprising, or being prepared from, these fullerene derivatives, compositions or formulations.. . ... Merck Patent Gmbh

03/30/17 / #20170092875

Organic electroluminescent device

The invention relates to organic electroluminescent devices containing cathodes, anodes and an emitting layer, containing a luminescent organic compound which is at a distance between the lowest triple state (t1) and the first excited single state (s1) of =0.15 ev (tadf-compound), and an organic compound with at least one triphenylene group and/or aza triphenylene group which comprise up to six aza-atoms (tp-compound).. . ... Merck Patent Gmbh

03/30/17 / #20170088776

Liquid crystal medium and electrooptical display containing same

The present invention relates to nematic liquid-crystal media of negative dielectric anisotropy which have a peak time (tmax.) of 0.25 ms or less, which is determined as described in the disclosure, and which preferably have a value of the quotient of the peak time and the square of the birefringence (tmax/Δn2) of 22 ms or less, and to the use of these liquid-crystal media in liquid-crystal displays, and to these liquid-crystal displays.. . ... Merck Patent Gmbh

03/30/17 / #20170088519

Amine derivatives as potassium channel blockers

The present invention relates to compounds useful in the modulation of potassium channel activity in cells, in particular the activity of kv1.3 channels found in t cells. The invention also relates to the use of these compounds in the treatment or prevention of autoimmune and inflammatory diseases, including multiple sclerosis, pharmaceutical compositions containing these compounds and methods for their preparation.. ... Merck Patent Gmbh

03/23/17 / #20170084844

Formulations of luminescent compounds

. . The present invention relates to a formulation comprising organic materials for the production of organic electronic devices having a low failure rate.. . ... Merck Patent Gmbh

03/23/17 / #20170084839

Organic semiconducting compounds

The invention relates to novel organic semiconducting compounds, which are small molecules or conjugated polymers, containing one or more isoindigo or thienoisoindigo based polycyclic units, to methods for their preparation and educts or intermediates used therein, to compositions, polymer blends and formulations containing them, to the use of the compounds, compositions and polymer blends as organic semiconductors in, or for the preparation of, organic electronic (oe) devices, especially organic photovoltaic (opv) devices, organic photodetectors (opd), perovskite based solar cells, organic field effect transistors (ofet) and organic light emitting diodes (oled), and to oe, opv, opd, ofet and oled devices comprising these compounds, compositions or polymer blends.. . ... Merck Patent Gmbh

03/23/17 / #20170081361

Hydroxystatin derivatives for the treatment of arthrosis

The present invention relates to compounds of the formula (i) and in particular to medicaments comprising at least one compound of the formula (i) for use in the treatment and/or prophylaxis of physiological and/or pathophysiological conditions in the triggering of which cathepsin d is involved, in particular for use in the treatment and/or prophylaxis of arthrosis, traumatic cartilage injuries arthritis, pain, allodynia or hyperalgesia.. . ... Merck Patent Gmbh

03/23/17 / #20170081317

Heteroaryl compounds as irak inhibitors and uses thereof

The present invention relates to compounds of formula i and pharmaceutically acceptable compositions thereof, useful as irak inhibitors.. . ... Merck Patent Gmbh

03/23/17 / #20170081307

Heteroaryl compounds as irak inhibitors and uses thereof

The present invention relates to compounds of formula i and pharmaceutically acceptable compositions thereof, useful as irak inhibitors.. . ... Merck Patent Gmbh

03/23/17 / #20170079965

Novel indolizine derivatives and their use in neurodegenerative diseases

The present invention relates to indolizine compounds, and pharmaceutically acceptable compositions thereof, useful as antagonists of p2x7, and for the treatment of p2x7-related disorders.. . ... Merck Patent Gmbh

03/16/17 / #20170077418

Organic electroluminescent device

. . . . The present invention relates to organic electroluminescent devices, the emitting layer thereof containing a blend of a luminescent material having a narrow singlet-triplet gap and a fluorescent emission material having high steric shielding.. . ... Merck Patent Gmbh

03/16/17 / #20170073843

Method for the preparation of fibers from a catalyst solution, and articles comprising such fibers

The present invention relates to a method for the preparation of fibers from a catalyst solution by electrospinning and further to articles comprising such fibers.. . ... Merck Patent Gmbh

03/16/17 / #20170073723

Method of detecting microbes carried in a non-liquid sample

A method and system of preparing a sample for microbial testing by providing a sample in a sample bag, a dry sterile growth medium in a bag, and a source of pure (type ii) water heated to a temperature of about 25-50° c., homogenizing the sample, reconstituting the dry medium with the heated type ii water, mixing the medium and sample to a homogenous consistency and incubating the sample for a period of time sufficient to allow the growth of microbes. A tankless water heater or a heat exchanger can be used to heat the water to a desired temperature. ... Merck Patent Gmbh

03/16/17 / #20170073580

Liquid crystalline medium

The present invention relates to a liquid-crystalline medium based on a mixture of polar compounds having negative dielectric anisotropy (Δ∈), which is distinguished by the fact that it has a value for the ratio γ1/Δn2 in the range 6-45 with a clearing point of >60° c. And a Δ∈ of ≦−2.3. ... Merck Patent Gmbh

03/16/17 / #20170073394

Robust antibody purification

The present invention refers to a method for the separation of host cell proteins (hcps), antibody fragments and low molecular weight substances from solutions containing antibodies.. . ... Merck Patent Gmbh

03/16/17 / #20170072017

Fgf-18 compound dosing regimen

The present invention provides a new dosing regimen for administration of fgf18 in the treatment of a cartilage disorder, such as osteoarthritis or cartilage injury. Specifically provided is a preferred treatment scheme comprising administrations every 3 weeks, 4 weeks or 5 weeks of an fgf-18 compound per treatment cycle. ... Merck Patent Gmbh

03/16/17 / #20170071936

Pyridazinone-amides derivatives

The present invention relates to compounds of formula (i) wherein r1, ra, rb and z have the meaning given in claim 1, and their use in the prophylaxis and treatment of diseases.. . ... Merck Patent Gmbh

03/09/17 / #20170069915

Stable catalyst ink formulations, methods of using such inks in fiber formation, and articles comprising such fibers

The present invention relates to stable catalyst ink formulations comprising am electrospinning polymer selected from halogen-comprising polymers. The present invention further relates to electrospinning of such ink formulation, to the so-obtained electrospun fibrous mat as well as to articles comprising such electrospun fibrous mat.. ... Merck Patent Gmbh

03/09/17 / #20170067915

Methods of evaluating quality of media suitable for removing anti-a or anti-b antibodies

Embodiments described herein relate to methods of evaluating quality of a chromatography media for removal of anti-a or anti-b antibodies from a sample, where the methods employ use of purified lectins.. . ... Merck Patent Gmbh

03/09/17 / #20170067914

Methods of evaluating quality of a chromatography media which binds anti-a or anti-b antibodies

Embodiments described herein relate to methods of evaluating quality of a chromatography media for removal of anti-a or anti-b antibodies from a sample, where the methods employ use of purified monoclonal igm-a and igm-b antibodies.. . ... Merck Patent Gmbh

03/09/17 / #20170066839

Novel affinity chromatography media for removal of anti-a and/or anti-b antibodies

Embodiments described herein relate to novel chromatography media for removing anti-a and/or anti-b antibodies from a sample, as well as methods of using the same. The media described herein have several advantages over previously described media including, acid and alkaline stability.. ... Merck Patent Gmbh

03/02/17 / #20170062736

Materials for electronic devices

The application relates to compounds having functional substituents in a specific spatial arrangement, to devices comprising same, and to the preparation and use thereof.. . ... Merck Patent Gmbh

03/02/17 / #20170062732

Materials for organic electroluminescent devices

The invention relates to compounds which are suitable for use in electronic devices, and electronic devices, in particular organic electroluminescent devices, containing said compounds.. . ... Merck Patent Gmbh

03/02/17 / #20170062725

Composition and method for preparation of organic electronic devices

The present invention relates to novel compositions comprising an organic semiconductor (osc) and one or more organic solvents. The composition is solid at a temperature of 25° c. ... Merck Patent Gmbh

03/02/17 / #20170056560

Implant comprising fgf-18

The invention relates to the field of pharmaceutical compositions. More particularly it is directed to substance delivery system (or implant), such as scaffolds and membranes, comprising an anabolic drug, such as a fibroblast growth factor 18 (fgf-18) compound, to methods of producing such delivery system, as well as use thereof. ... Merck Patent Gmbh

03/02/17 / #20170056554

Fgf-18 in graft transplantation and tissue engineering procedures

The present invention provides a new method related to regenerative medicine for the treatment of cartilage disorders, osteoarthritis and cartilage injury in particular. More particularly, it relates to an fgf-18 compound for use in tissue engineering and graft procedures, such as osteochondral or cartilage transplantation or autologous chondrocyte implantation (aci).. ... Merck Patent Gmbh

03/02/17 / #20170056474

Fgf-18 compound dosing regimen

The present invention provides a new dosing regimen for administration of fgf18 in the treatment of a cartilage disorder, such as osteoarthritis or cartilage injury. Specifically provided is a preferred treatment scheme comprising administrations every 2 weeks of an fgf-18 compound per treatment cycle. ... Merck Patent Gmbh

02/23/17 / #20170051331

Sample preparation device and method of preparing a sample for sterility testing

. . A sample preparation device comprising a first chamber containing a first movable piston separating a first volume upstream and a second volume downstream the first piston, a second chamber containing a second movable piston separating a third volume upstream and a fourth volume downstream the second piston, and an inlet to the first volume and an outlet from the first volume. The first volume is connected with the third volume by a first communication path and the second volume is connected with the fourth volume by a second communication path.. ... Merck Patent Gmbh

02/23/17 / #20170051204

Liquid crystalline medium

The present invention relates to a liquid-crystalline medium based on a mixture of polar compounds having negative dielectric anisotropy (Δ∈), which is distinguished by the fact that it has a value for the ratio γ1/Δn2 in the range 6-45 with a clearing point of >60° c. And a Δ∈ of ≦−2.3. ... Merck Patent Gmbh

02/23/17 / #20170049892

Process for producing of inorganic particulate material

The present invention is directed to a process for producing inorganic particulate material, the material obtainable by such process, a modified release delivery system comprising the material and the use of the material for the administration of a bioactive agent.. . ... Merck Patent Gmbh

02/16/17 / #20170044588

Method for detecting micro-colonies growing on a membrane or an agarose medium of a sample and a sterility testing apparatus

. . . . The present invention is directed to a method and an apparatus for detecting micro-colonies growing on a membrane or an agarose medium of a sample in a closed device. According to the invention the sample is irradiated with a light incident at an angle (β) with respect to the normal to the membrane or the surface of the agarose medium from outside the device. ... Merck Patent Gmbh

02/16/17 / #20170044439

Reactive mesogen based polymer particles

This invention relates to a process for the preparation of monodisperse optical and shape anisotropic polymer particles comprising monomer units of at least one reactive mesogen, such particles per se, the use of these particles for the preparation of optical, electrooptical, electronic electrochemical, electrophotographic, electrowetting and electrophoretic displays and/or devices and security, cosmetic, decorative, and diagnostic applications, and electrophoretic fluids and displays.. . ... Merck Patent Gmbh

02/16/17 / #20170044376

Composition for forming low-refractive-index film, method of forming low-refractive-index film, and low-refractive-index film and antireflective film both formed by the formation method

Provided is a composition for forming a low-refractive-index film, which exhibits an excellent antireflective function even when applied in a single layer and does not affect the environment, and which is characterized by comprising (a) an inorganic polysilazane and (b) at least one organic polymer selected from a silazane-containing organic polymer, a siloxazane-containing organic polymer and a ureasilazane-containing organic polymer, wherein the ratio (a):(b) is 40:60-17:83 by weight.. . ... Merck Patent Gmbh

02/16/17 / #20170044374

Filler pigments

Filler pigments based on platelet-shaped substrates, which are coated with barium sulfate and at least two metal oxides and/or metal hydroxides are highly suitable as filler pigments especially for cosmetic formulations.. . ... Merck Patent Gmbh

02/09/17 / #20170040573

Electronic device with thin porous layers of mixed metal oxides

. . The present invention relates to oleds (organic light emitting devices) with increased light outcoupling, to a process for the production of oleds comprising additional light outcoupling layers, and to the use thereof.. . ... Merck Patent Gmbh

02/09/17 / #20170037315

Liquid-crystalline medium

The present invention relates to a liquid-crystalline medium (lc medium), to the use thereof for electrooptical purposes and to lc displays comprising this medium.. . ... Merck Patent Gmbh

02/02/17 / #20170033296

Materials for organic electroluminescent devices

The invention relates to compounds of the formula (1) which are suitable for use in electronic devices, in particular organic electroluminescent devices.. . ... Merck Patent Gmbh

02/02/17 / #20170030644

Apparatus and method for removing moisture from a surface in a container

An apparatus (10; 20; 30; 40; 60) for removing moisture from a surface (522) in a container (500; 5001, 5002; 500′), characterized by: a centrifuging element comprising a mount (140; 1401, 1402) for attaching said container (500; 5001, 5002; 500′) to said centrifuging element and a drive (105) coupled to said mount (140; 1401, 1402) for rotating said attached container (500; 5001, 5002; 500′) and centrifuging said moisture off said surface (522) in said attached container (500; 5001, 5002; 500′); and a heating element (200) for providing heat energy and evaporating said moisture from said surface (522) in said attached container (500; 5001, 5002; 500′), and a corresponding method.. . ... Merck Patent Gmbh

02/02/17 / #20170029702

Liquid crystal material

The present application relates to a liquid-crystalline material which comprises at least one dye compound and at least one compound of a formula (ia) or (ib). The liquid-crystalline material is suitable for use in optical switching devices, in particular in devices for the homogeneous regulation of the passage of light through an area.. ... Merck Patent Gmbh

02/02/17 / #20170029292

Biocidal purification device

A biocidal fluid purification cap (2) for a fluid container (1), preferably one storing purified water for use in laboratory environments and especially purified water for cell culture and water for molecular biology. The purification cap (2) includes a cap body (3) including an engagement feature (20) for removably attaching the cap body (3) to a mating engagement feature on a spout of the fluid container (1) to hermetically close a spout opening, at least one led (7a) adapted to emit light in the uv-c range, electronic circuitry (15) for driving the led(s) (7a), and a power supply for the electronic circuitry (15). ... Merck Patent Gmbh

01/26/17 / #20170025612

Organic electronic compositions and device thereof

. . The present invention relates to organic electronic devices, and more specifically to organic field effect transistors, comprising a dielectric layer that comprises a polycycloolefinic polymer with an olefinic side chain.. . ... Merck Patent Gmbh

01/26/17 / #20170023581

Method for detecting protein modifications using specific antibodies

Method, kit and composition for analyzing analytes for modifications using modification site specific antibodies to bind an analyte with his specific modification sites of interest to different dyes simultaneously with an antibody which is specific to the non-modificated analyte binding to another dye to determine the concentration of the analyte for quantification of the modified analyte in the identical sample.. . ... Merck Patent Gmbh

01/26/17 / #20170021355

Fluid transfer device and process of aseptically transferring a fluid

A fluid transfer device comprising a first reservoir (1) having a predetermined sub-ambient pressure and volume and a presealed opening (1a), a second reservoir (2) containing a predetermined volume of a fluid (m) and having a presealed opening (2a), and a chamber (3) having an internal space (6) and an inlet (4) to the space (6) adapted to be connected to the opening (2a) of the second reservoir (2) and an outlet (5) from the space (6) adapted to be connected to the opening (1a) of the first reservoir (1).. . ... Merck Patent Gmbh

01/19/17 / #20170018722

Materials for organic electroluminescent devices

. . Triphenylene derivatives, in particular for use as triplet matrix materials in organic electroluminescent devices, one of example of which is represented by formula 1. The invention furthermore relates to a process for the preparation of the triphenylene derivatives and to electronic devices comprising the triphenylene derivatives.. ... Merck Patent Gmbh

01/19/17 / #20170018710

Materials for electronic devices

The invention relates to phenanthrene compounds comprising one or more arylamino groups. Said compounds can be used in electronic devices, in particular oled's.. ... Merck Patent Gmbh

01/19/17 / #20170016592

Down conversion

The present invention relates inter alia to an array comprising i times j array elements, wherein the array elements may comprise at least one quantum dot and/or at least one photoluminescent compound. Further the present invention relates to devices comprising these arrays. ... Merck Patent Gmbh

01/19/17 / #20170014325

2-pyrones

The present invention relates to the use of compounds of the formula (i) for the care, preservation or improvement of the general condition or appearance of the skin or hair, and to preparations comprising compounds of the formula (i).. . ... Merck Patent Gmbh

01/12/17 / #20170012221

Materials for organic electroluminescent devices

The present invention relates to coordination compounds which are used in an electron-transport layer in electronic devices, to ligands, and to the use thereof for the preparation of metal complexes, to a layer, and to an electronic device which comprise the compounds according to the invention, and to a process for the preparation of the compounds according to the invention.. . ... Merck Patent Gmbh

01/12/17 / #20170012219

Materials for organic light-emitting devices

The invention relates to compounds which are suitable for use in electronic devices, and electronic devices, in particular organic electroluminescent devices, containing said compounds.. . ... Merck Patent Gmbh

01/12/17 / #20170008857

Heteroaryl compounds as btk inhibitors and uses thereof

The present invention relates to pyrimidine compounds, and pharmaceutically acceptable compositions thereof, useful as btk inhibitors.. . ... Merck Patent Gmbh

01/12/17 / #20170008836

Fluorinated tensides

The present invention relates to novel compounds containing fluorinated end groups, to the use thereof as surface-active substances, and to compositions comprising these compounds.. . ... Merck Patent Gmbh

01/05/17 / #20170003531

Light modulation element

. . . . . . The invention provides a light modulation element comprising a flexoelectric polarisable liquid-crystalline medium, characterized in that the switching from a boundary state a to a boundary state b comprises a combination of a distinct flexoelectric switching regime and a distinct dielectric switching regime upon application of an electric field. Furthermore, the present invention relates to the use of such a light modulation element in an electro-optical device, i.e. ... Merck Patent Gmbh

01/05/17 / #20170002395

Sample preparation unit and sample preparation device

Sample preparation unit, preferably for sterility testing: a housing body including at least two ports adapted to serve as fluid inlet and/or fluid outlet, a membrane support, and a lid part such that a membrane chamber is defined adjacent said membrane support. One of at least two ports is arranged so as to allow a fluid transfer to/from a first volume of the membrane chamber at a position upstream of a membrane to be placed on the membrane support, and the other ports arranged to allow fluid transfer to/from a second volume of said membrane chamber at a position downstream of a membrane to be placed on said membrane support. ... Merck Patent Gmbh

01/05/17 / #20170002290

Electro-rheological fluid and haptic device

The present invention relates to an electro-rheological fluid comprising particles of at least one inorganic or organic material suspended in a polar liquid crystalline medium, the use of such electro-rheological fluid in an haptic device, an haptic device itself, a method of the production of such haptic device and the use of such haptic device in electro-optical devices.. . ... Merck Patent Gmbh

01/05/17 / #20170002267

Liquid crystal medium

The present invention relates to a liquid crystalline medium comprising a polymerizable compound, to a process for its preparation, to its use for optical, electro-optical and electronic purposes, in particular in liquid crystalline displays, especially in a liquid crystalline display of the polymer sustained alignment (psa) type, and to a liquid crystalline display, especially a psa display, comprising it.. . ... Merck Patent Gmbh

01/05/17 / #20170002203

Dye compounds

The present application relates to mixtures comprising at least one dye compound having a diketopyrrolopyrrole structure and at least one further liquid-crystalline compound. The application furthermore relates to the use of the mixtures in devices for regulating the entry of light into a space.. ... Merck Patent Gmbh








ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009



###

This listing is an abstract for educational and research purposes is only meant as a recent sample of applications filed, not a comprehensive history. Freshpatents.com is not affiliated or associated with Merck Patent Gmbh in any way and there may be associated servicemarks. This data is also published to the public by the USPTO and available for free on their website. Note that there may be alternative spellings for Merck Patent Gmbh with additional patents listed. Browse our Agent directory for other possible listings. Page by FreshPatents.com

###