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National Cancer Center patents


Recent patent applications related to National Cancer Center. National Cancer Center is listed as an Agent/Assignee. Note: National Cancer Center may have other listings under different names/spellings. We're not affiliated with National Cancer Center, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "N" | National Cancer Center-related inventors


Magnetic nanostructure for detecting and isolating cell-free dna comprising cationic polymer and magnetic-nanoparticle-containing conductive polymer

Provided is a magnetic nanostructure for detecting and isolating cell-free dna (cfdna) that including a cationic polymer and a magnetic-nanoparticle-containing conductive polymer. The magnetic nanostructure for detecting and isolating cfdna according to the subject matter can significantly improve detection and extraction efficiencies of dna present in a urine, csf, blood plasma, or blood sample, and exhibits an enhanced sensitivity. ... National Cancer Center

Functional cell sheet using electrically activated conductive polymer, and method of producing same

The present invention relates to a functional cell sheet using an electroactive conductive polymer and a method of preparing the same, and more particularly, to a cell sheet for tissue engineering which is a growth factor-immobilized cell sheet formed in a single-layer or 3d multilayer form and a composition for inducing osteogenic differentiation including the same.. . ... National Cancer Center

Method for quantifying monoclonal antibody

The present invention provides a method for quantifying a monoclonal antibody, the method including: a step of performing selective protease digestion of a monoclonal antibody as a measurement target by bringing a porous body in which the monoclonal antibody is immobilized in pores into contact with fine particles onto which a specific protease is immobilized; and a step of detecting a peptide fragment that is obtained from the digestion and contains an amino acid derived from a cdr2 region of a heavy chain or a light chain of the monoclonal antibody.. . ... National Cancer Center

Family tree construction supporting method and family tree construction supporting device

Provided is a non-transitory computer-readable storage medium storing a program causing a computer to execute a process, the process including: receiving a first operation that specifies a person symbol from a plurality of person symbols representing persons present in a family tree; displaying a plurality of first candidate person symbols capable of being connected with the person symbol specified by the received first operation by referring to a first storage unit that stores attribute information with respect to each of a plurality of persons; receiving a second operation that selects a first candidate person symbol from the plurality of first candidate person symbols that have been displayed; and displaying the first candidate person symbol selected by the received second operation while the selected first candidate person symbol is being connected with the person symbol specified by the first operation.. . ... National Cancer Center

In vivo radiation amount measuring instrument

The present invention relates to an in vivo radiation amount measuring instrument. An in vivo radiation amount measuring instrument according to the present invention comprises: a main body elongated along an in vivo inserting direction and capable of supplying a fluid; an expanding part having at least a portion thereof fixed or connected to the main body and capable of being expanded and contracted by means of the outflow/inflow of the fluid; and a radiation measuring part disposed on the expanding part and measuring the amount of surface radiation distribution on in vivo tissue which the expanding part contacts by expanding.. ... National Cancer Center

Combined composition for preventing or treating cancer comprising a benzophenone thiazole derivatives as a vda and topoisomerase inhibitor

The present invention relates to a pharmaceutical combined composition for preventing or treating cancer comprising a compound of formula 1 or a pharmaceutically acceptable salt thereof and topoisomerase inhibitor as active ingredients. The pharmaceutical combined composition of the present invention specifically inhibits cell proliferation and induces apoptosis as to various cancers such as colorectal cancer and ovarian cancer that a vascular disrupting agent cannot treat due to a complex inhibition mechanism of neoplasm of the compound of formula 1 and the pharmaceutically acceptable salt thereof and topoisomerase inhibitor, and thereby it can be usefully used for preventing and treating cancer.. ... National Cancer Center

Magnetic nanostructure for detecting and isolating circulating tumor cells comprising antibody- and magnetic nanoparticle-conjugated conductive polymer

Disclosed is a magnetic nanostructure for detecting and isolating circulating tumor cells including a conductive polymer to which an antibody and magnetic nanoparticles are bound, which enables circulating tumor cells from early cancer patients and various circulating tumor cell types to be effectively detected using a small amount of blood, circulating tumor cells to be monitored with the naked eye through colorimetric detection, and a very small amount of circulating tumor cells present in blood to be efficiently captured with a strong magnetic field generated by a large amount of the loaded magnetic nanoparticles; in detecting, isolating, and collecting the circulating tumor cells in a very small amount, a long nanowire structure and various antibody types are used, whereby contact with cancer cells may be increased and strong bonding may be formed; sensitivity is increased and various interactions with cancer cells are facilitated, thereby exhibiting increased detection and isolation effects.. . ... National Cancer Center

Methods for isolating and proliferating autologous cancer antigen-specific cd8+ t cells

Provided is a method for isolating and proliferating autologous cancer antigen-specific cd8+t cells, and more particularly, a method for selecting an epitope recognized by cd8+ t cells from autologous cancer antigens present in blood of individual cancer patients; and isolating autologous cancer antigen-specific cd8+ t cells by using a peptide of the selected epitope, and a method of massively proliferating cd8+ t cells by using the method. According to the present invention, it is possible to isolate autologous cancer antigen-specific cd8+ t cells by using the peptide of the cd8 t cell epitope of the autologous cancer antigen present in blood of individual cancer patients instead of a heterologous antigen. ... National Cancer Center

Fluorescent image system

The present invention relates to a fluorescent image system capable of generating white light by mixing three monochromatic lights, i.e. Red, green and blue monochromatic lights, having a narrow band wavelength, instead of white light of constant wavelength; providing a fluorescent image-use light source that generates a mixed light by adding a fluorescent excitation light source suitable for fluorescent substances; and photographing a general image and fluorescent image simultaneously with the light sources. ... National Cancer Center

Augmented reality image projection system

The present disclosure relates to an augmented reality (ar) image projection system capable of simultaneously capturing a real image and projecting an ar image, and capable of applying same to a subject requiring precise work or in an environment having spatial restrictions. The present disclosure includes a real image capture device for capturing a real image illuminated by invisible rays without interference with visible rays, and an ar image projection device for projecting an ar image, wherein the real image capture device captures a real image and the ar image projection device projects an ar image through the same optical axis. ... National Cancer Center

Method and kit for the detection of pancreatic dysfunction

The purpose of the present invention is to provide a simple and highly accurate method for detecting pancreatic exocrine dysfunction with minimal invasiveness to a subject. The method comprising in vitro measurement of two apoa2 protein variants, mutants thereof and/or fragments thereof in a body fluid sample derived from the subject and detection of the presence or absence of pancreatic exocrine dysfunction on the basis of the measured amounts, and a detection kit for pancreatic exocrine dysfunction including antibodies that can specifically bind to said proteins are provided.. ... National Cancer Center

Method and kit for the detection of biliary tract cancer (as amended)

The present invention provides a method for detecting biliary tract cancer by measuring the amounts of apoa2 protein variants in a test sample with anti-apoa2 antibodies, the anti-apoa2 antibodies for use in the above method and a detection kit for biliary tract cancer including the above antibodies.. . ... National Cancer Center

Pharmaceutical composition for inhibiting growth of cancer stem cells, containing aldehyde inhibitor and biguanide-based compound

The present invention relates to a pharmaceutical composition for inhibiting growth of cancer stem cells, containing an aldehyde inhibitor and a biguanide-based compound. The pharmaceutical composition according to the present invention contains a combination of an aldehyde inhibitor and a biguanide-based compound, which can effectively inhibit the growth of cancer stem cells such as neurospheres and can also inhibit the proliferation, invasion and metastasis of cancer cells, thereby preventing and/or treating cancer such as brain cancer.. ... National Cancer Center

Pancreatic cancer detection kit or device, and detection method

This invention provides a kit or a device for the detection of pancreatic cancer, comprising a nucleic acid(s) capable of specifically binding to a mirna(s) in a sample from a subject, and a method for detecting pancreatic cancer, comprising measuring the mirna(s) in vitro.. . ... National Cancer Center

09/28/17 / #20170273654

X-ray ct apparatus

An x-ray ct apparatus according to an embodiment includes processing circuitry. The processing circuitry is configured to detect x-rays that have passed through a subject by using a detector and to acquire projection data on a basis of a detection result. ... National Cancer Center

08/24/17 / #20170240902

Method and composition for the treatment, prevention, and diagnosis of cancer containing or derived from cancer stem cells

The invention provides a method and composition for the treatment, prevention, and diagnosis of cancer containing or derived from cancer stem cells.. . ... National Cancer Center

07/27/17 / #20170211147

Method of predicting reaction to sorafenib treatment using gene polymorphism

The present invention relates to a method of predicting reaction to sorafenib treatment using genetic polymorphism. More specifically, for the reaction to sorafenib treatment according to the present invention, it is possible to predict the reaction of a test object to sorafenib treatment by using an anticancer-target gene which is expressed in a biological sample of a liver cancer patient as a biomarker, whereby a proper drug is administered to a liver cancer patient and an optimal treatment effect is attained, so that inconvenience of a patient can be reduced, costs for treatment can be reduced, and an individually tailored chemotherapy can more effectively be implemented by administration of a patient-specific anticancer agent.. ... National Cancer Center

07/06/17 / #20170189371

Hnf4-alpha antagonist and use thereof

Provided is a hepatocyte nuclear factor 4 alpha (hnf4-α) antagonist and a use thereof. The hnf4-α antagonist selected in the present invention was confirmed to specifically bind to the ligand binding domain of hnf4-α, thereby inhibiting the activity of hnf4-α. ... National Cancer Center

06/15/17 / #20170166975

Liver cancer detection kit or device, and detection method

It is intended to provide a kit or device for the detection of liver cancer and a method for detecting liver cancer. The present invention relates to a kit or device for the detection of liver cancer, comprising a nucleic acid capable of specifically binding to mirna in a sample of a subject, and a method for detecting liver cancer, comprising measuring the mirna in vitro.. ... National Cancer Center

05/11/17 / #20170130278

Lung cancer detection kit or device, and detection method

It is intended to provide a kit or a device for the detection of lung cancer and a method for detecting lung cancer. The present invention provides a kit or a device for the detection of lung cancer, comprising a nucleic acid capable of specifically binding to a mirna in a sample from a subject, and a method for detecting lung cancer, comprising measuring the mirna in vitro.. ... National Cancer Center

05/11/17 / #20170130276

Stomach cancer detection kit or device, and detection method

This invention relates to a kit or a device for the detection of stomach cancer and a method for detecting stomach cancer, and provides a kit or a device for the detection of stomach cancer, comprising a nucleic acid(s) capable of specifically binding to a mirna(s) in a sample from a subject, and a method for detecting stomach cancer, comprising measuring the mirna(s) in vitro.. . ... National Cancer Center

05/11/17 / #20170130275

Breast cancer detection kit or device, and detection method

It is intended to provide a kit or a device for the detection of breast cancer and a method for detecting breast cancer. The present invention provides a kit or a device for the detection of breast cancer, comprising nucleic acid(s) capable of specifically binding to a mirna in a sample of a subject, and a method for detecting breast cancer, comprising measuring the mirna in vitro.. ... National Cancer Center

05/11/17 / #20170130274

Colorectal cancer detection kit or device, and detection method

It is intended to provide a kit or a device for the detection of colorectal cancer and a method for detecting colorectal cancer. The present invention provides a kit or a device for the detection of colorectal cancer, comprising a nucleic acid capable of specifically binding to a mirna in a sample from a subject, and a method for detecting colorectal cancer, comprising measuring the mirna in vitro.. ... National Cancer Center

05/11/17 / #20170130273

Esophageal cancer detection kit or device, and detection method

It is intended to provide a kit or a device for the detection of esophageal cancer and a method for detecting esophageal cancer. The present invention provides a kit or a device for the detection of esophageal cancer, comprising nucleic acid(s) capable of specifically binding to mirna(s) in a sample f a subject, and a method for detecting esophageal cancer, comprising measuring the mirna in vitro.. ... National Cancer Center

05/11/17 / #20170129102

Apparatus for controlling stiffness of output link in moving mechanism

A stiffness control apparatus includes a base member, an output link configured to move along a plane parallel to a surface of the base member, and at least one stiffness control unit configured to control stiffness of the output link. The at least one stiffness control unit includes a shaft including a first end and a second end, the first end being rotatably coupled to the base member, a rotating member including an elongated hole into which the second end of the shaft is movably inserted, and rotatably arranged by the shaft at a position having contact with the output link on an outer side or an inner side the output link, and an elastic member between the second end of the shaft and at least one inner wall of the elongated hole in a longitudinal direction thereof.. ... National Cancer Center

05/04/17 / #20170121779

Prostate cancer detection kit or device, and detection method

An object of the present invention is to provide a kit or a device for the detection of prostate cancer and a method for detecting prostate cancer. The present invention provides a kit or a device for the detection of prostate cancer, comprising a nucleic acid capable of specifically binding to a mirna in a sample of a subject, and a method for detecting prostate cancer, comprising measuring the mirna in vitro.. ... National Cancer Center

04/20/17 / #20170107581

Biliary tract cancer detection kit or device, and detection method

The present invention provides a kit or device for the detection of biliary tract cancer, and a method for detecting biliary tract cancer. The present invention relates to a kit or device for the detection of biliary tract cancer, comprising a nucleic acid capable of specifically binding to mirna in a sample of a subject, and a method for detecting biliary tract cancer, comprising measuring the mirna in vitro.. ... National Cancer Center

03/16/17 / #20170071877

Pharmaceutical composition for cancer treatment containing gossypol and phenformin as active ingredients

The present invention relates to a pharmaceutical composition for cancer treatment containing gossypol and phenformin as active ingredients. Specifically, the combinative treatment with gossypol and phenformin was verified to have a significantly higher anticancer activity than a single treatment with gossypol and phenformin alone. ... National Cancer Center

03/16/17 / #20170071601

Suturing device for surgery

A suturing device for surgery according to the present invention comprises: a body unit; a pair of suturing operation units which are supported by a frontal end of the body unit and are rotated between a first mode, in which the pair of suturing operation units are tooth-engaged to each other with a suture area therebetween so that a suturing needle supported by any one of the pair of suturing operation units penetrates through the suture area and is transferred to the other suturing operation unit, and a second mode, in which the suturing needle supported by the other suturing operation unit in the first mode is transferred to any one of the pair of suturing operation units; and a driving unit for providing a driving force to at least one of the pair of suturing operation units so that the pair of suturing operation units are rotated between the first mode and the second mode.. . ... National Cancer Center

02/23/17 / #20170051275

Nanostructure for detecting cell-free dna using conductive polymer and the use thereof

Disclosed is a structure for detecting cell-free dna using a conductive polymer and the use thereof. More particularly, a nanostructure composed of a surface-modified conductive polymer for isolating and detecting cell-free dna is disclosed. ... National Cancer Center

02/02/17 / #20170028086

Multipurpose medical image indicator and method for manufacturing the same

The present disclosure concerns a medical image indicator. More particularly, it concerns the multipurpose medical image indicator including more than one of fluorophores and mri contrast agent/ct contrast agent and method for manufacturing same. ... National Cancer Center

01/19/17 / #20170014480

Peptides derived from ncapg2 and their use

Ncapg2, a component of condensin complex ii, protein and novel peptides derived from the protein are provided. The peptide may include a fragment of the ncapg2 protein. ... National Cancer Center








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