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Nogra Pharma Limited patents


Recent patent applications related to Nogra Pharma Limited. Nogra Pharma Limited is listed as an Agent/Assignee. Note: Nogra Pharma Limited may have other listings under different names/spellings. We're not affiliated with Nogra Pharma Limited, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "N" | Nogra Pharma Limited-related inventors


Methods for treating inflammatory bowel disease

Methods of treating a subject with ibd with an anti-smad7 therapy, such as a smad7 antisense oligonucleotide, to reduce crp levels are disclosed. Methods of treating and managing ibd in a subject using an anti-smad7 therapy, such as a smad7 antisense oligonucleotide, based on crp levels are also disclosed. ... Nogra Pharma Limited

Methods for monitoring responsiveness to anti-smad7 therapy

Methods for monitoring whether a subject will be sensitive or resistant to treatment with an anti-smad7 therapy are disclosed. The methods are based on the determining of the amount of ccr9+ foxp3+ t cells, ccr9+ ifn-gamma+ t cells, ccr9+il17a+ t cells, foxp3+ t cells, ifn-gamma+ t cells, and/or il17a+ t cells in a sample from the subject. ... Nogra Pharma Limited

Methods of treating fibrosis

The present disclosure is directed in part to methods of treating fibrosis, e.g., hepatic fibrosis and/or intestinal fibrosis, comprising administering to a patient in need thereof an effective amount of a disclosed compound.. . ... Nogra Pharma Limited

Methods of treating lactose intolerance

Disclosed herein are methods for treating lactose intolerance, including compounds that may be specific or modulate pparγ receptors.. . ... Nogra Pharma Limited

Antisense oligonucleotides (odn) against smad7 and uses thereof in medical field

The invention relates to antisense oligonucleotidic sequences (odn) against smad7 suitably modified, and their uses in medical field as therapeutic biological agents, in particular in the treatment of chronic inflammatory bowel disease, such as crohn's disease and ulcerative colitis.. . ... Nogra Pharma Limited

Antisense oligonucleotides (odn) against smad7 and uses thereof in medical field

The invention relates to antisense oligonucleotidic sequences (odn) against smad7 suitably modified, and their uses in medical field as therapeutic biological agents, in particular in the treatment of chronic inflammatory bowel disease, such as crohn's disease and ulcerative colitis.. . ... Nogra Pharma Limited

Methods and compositions for treating a subject with a smad7 antisense oligonucleotide

The present invention relates to treatment of inflammatory bowel disease (e.g., crohn's disease and ulcerative colitis) using antisense nucleotides that are directed against polymorphic forms (e.g., those containing single nucleotide polymorphisms) of the smad7 mrna. The invention thus relates to treatment methods for subjects having polymorphic forms of smad7 and antisense oligonucleotides that specifically target smad7 mrna transcripts containing polymorphisms.. ... Nogra Pharma Limited

Bicyclic heterocycles capable of modulating t-cell responses, and methods of using same

The present disclosure is directed in part to bicyclic heterocycles, such as a compound represented by formula (i) or (ii) as disclosed herein, and their use in treating medical disorders, such as immune inflammatory disorders such as crohn's disease, ulcerative colitis, rheumatic disorders, psoriasis, and allergies. The compounds are contemplated to modulate t cell responses.. ... Nogra Pharma Limited

Alkylamido compounds and uses thereof

Disclosed herein are compounds that may be specific to ppar and/or egf receptors, and methods of making and using same.. . ... Nogra Pharma Limited

Aryl receptor modulators and methods of making and using the same

The present invention is generally directed towards compounds capable of binding the aryl hydrocarbon receptor and modulating its activity, methods of treating inflammatory conditions such as crohn's disease using such compounds, and pharmaceutical compositions comprising such compounds. Also provided are methods of increasing levels of il-22 in a subject and/or decreasing levels of ifn-γ in a subject.. ... Nogra Pharma Limited

Antisense compositions and methods of making and using same

The present invention provides pharmaceutical formulations for oral administration of antisense oligonucleotides, such as antisense oligonucleotides against smad7. The pharmaceutical formulations can be used to treat crohn's disease, ulcerative colitis and chronic inflammatory bowel disease.. ... Nogra Pharma Limited

Methods for preventing or reducing colon carcinogenesis

The present invention is directed in part to methods of preventing or reducing colon carcinogenesis comprising administering to a patient at risk of colorectal cancer, a pharmaceutical preparation comprising disclosed chemopreventive. In another aspect, the invention is directed to methods attenuation of oxygen free radicals comprising administrating to a patient in need thereof an antioxidant effective amount of a compound represented by formula i, iia or iib as disclosed herein.. ... Nogra Pharma Limited








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