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Northeastern University patents

Recent patent applications related to Northeastern University. Northeastern University is listed as an Agent/Assignee. Note: Northeastern University may have other listings under different names/spellings. We're not affiliated with Northeastern University, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "N" | Northeastern University-related inventors

Low-frequency disturbance and high-speed impact type high-pressure true triaxial test apparatus and method

A high-pressure true triaxial test apparatus with capacity of low-frequency disturbance and high-speed impact includes static and dynamic loading frames, four static loading actuators, two dynamic loading actuators and an shpb mechanism, wherein all actuators are connected with a hydraulic station system; a hollow way is formed in the axial center of each piston shaft of the dynamic loading actuators, a dynamic pressure sensor adopting a hollow ring structure is mounted at the end part of each piston shaft, and the shpb mechanism applies a high-speed impact load on a rock sample through the dynamic pressure sensors respectively; and the dynamic loading actuators adopt a static pressure oilway balance support sealing manner and are connected with the hydraulic station system, each oilway is provided with an energy accumulator, and flow is increased by the servo valves to drive pistons to perform dynamic response.. . ... Northeastern University

Methods for generating neutralizing anti-pathogen antibodies by directing the humoral response toward desired epitopes

Methods for generating antibodies to immuno-subdominant epitopes of elusive pathogens and vaccines and methods of vaccinating subjects against elusive pathogens are disclosed. The methods include targeting immunodominant b cells to undergo apoptosis, for example, while simultaneously targeting the germinal center (gc) reaction toward preferential selection and differentiation of b cells that produce broadly neutralizing antibody against a targeted pathogen.. ... Northeastern University

Systems for producing cellular immunotherapeutics and methods of use thereof

Devices, systems, and methods can be used for the automated production of dendritic cells (dc) from dendritic cell progenitors, such as monocytes obtained from peripheral blood, and the automated generation of immunotherapeutic products from those dendritic cells, all within a closed system. The invention makes it possible to obtain sufficient quantities of a subject's own dc for use in preparing and characterizing vaccines, for activating and characterizing the activation state of the subject's immune response, and to aid in preventing and/or treating cancer or infectious disease.. ... Northeastern University

Methods, systems, and devices for optical sectioning

Methods, systems, and devices described herein enable single-image optical sectioning, even at depth within turbid media, such as human skin or other tissue. Embodiments can eliminate the need for multiple image samples or raster scans, making in-vivo or live biological imaging easier and faster than multi-image sectioning techniques. ... Northeastern University

Brush polymer-assisted compaction of oligonucleotides

The disclosed subject matter relates to brush polymer-oligonucleotide conjugates comprising oligonucleotides covalently attached to the backbone of a non-cationic, sterically congested brush polymer and the use of such polymer-oligonucleotide conjugates in antisense gene regulation and as diagnostic agents.. . ... Northeastern University

Fire-retardant nanocellulose aerogels, and methods of preparation and uses thereof

Disclosed are multilayered aerogel nanocomposite materials, and methods of making and using them.. . ... Northeastern University

Microdroplet based bioassay platform

. . Platform technology involving aqueous microdroplet reaction vessels created, arrayed, and characterized by imaging microscopy in a microfluidic device are applied to a wide variety of bioassays involving the detection and phenotypic characterization of single cells. The bioassays include the rapid and automated detection of microbial pathogens and their antibiotic sensitivity from patient samples as well as the characterization of immune responses using a patient's own cells, including the killing of tumor cells.. ... Northeastern University

Reduction of metal/semi-metal oxides

This invention is concerned with the reduction of metal and/or semi-metal oxides. More particularly the invention relates to a method and apparatus adapted to produce silicon by reduction of silicon oxides. ... Northeastern University

Biomolecular processing platform and uses thereof

The present invention relates to a device comprising a biomolecular processor. Each biomolecular processor has one or more bioreactor chambers defined by a solid substrate; a support structure within each bioreactor; a cleaving enzyme immobilized to the support structure and operatively positioned within the bioreactor chamber to cleave monomer or multimer units of a biopolymer molecule operatively engaged by the cleaving enzyme; and one or more time-of-flight channels formed in the solid substrate and fluidically coupled to said one or more bioreactor chambers. ... Northeastern University

Method for analyzing biological specimens by spectral imaging

A method for analyzing biological specimens by spectral imaging to provide a medical diagnosis includes obtaining spectral and visual images of biological specimens and registering the images to detect cell abnormalities, pre-cancerous cells, and cancerous cells. This method eliminates the bias and unreliability of diagnoses that is inherent in standard histopathological and other spectral methods. ... Northeastern University

Heparin-binding cationic peptide self-assembling peptide amphiphiles useful against drug-resistant bacteria

Disclosed are peptides comprising an amphiphilic backbone and a cationic heparin-binding motif peptide. The peptides can be used in methods of antimicrobial treatment.. ... Northeastern University

Dendritic cell generator

Devices, systems, and methods can be used for the automated production of dendritic cells (dc) from dendritic cell progenitors, such as monocytes obtained from peripheral blood. The invention makes it possible to obtain sufficient quantities of a subject's own dc for use in preparing and characterizing vaccines, for activating and characterizing the activation state of the subject's immune response, and to aid in preventing and/or treating cancer or infectious disease.. ... Northeastern University

Method and device for cultivation and analysis of novel microbial species with unknown growth requirements

The invention provides devices and methods for automatically preparing pure cultures of microbial cells under native environmental conditions. The devices and methods permit the discovery and investigation of novel microorganisms having unknown culture requirements from natural environments and microbiomes. ... Northeastern University

Method for dedifferentiating and culturing microbial species

Methods and devices useful for reprogramming microbial cells to grow under different culture conditions are provided. The methods and devices can be used to prepare cultures of new, previously uncharacterized microbial species and for identifying laboratory conditions to culture, propagate, and study microbes that do not grow under standard laboratory conditions. ... Northeastern University

05/24/18 / #20180145771

Method and apparatus for wireless communications

Embodiments disclosed herein may be implemented in the form of a method or corresponding apparatus for receiving or transmitting network communications carried at acoustic wavelengths via an acoustic medium. The corresponding method or apparatus may include a gate-level digital hardware module communicatively coupled to a communications module and define therein logic blocks configured to perform respective primitive processing functions, sequences of the logic blocks being capable of processing data units in accordance with any of the multiple communications protocols on a data unit-by-data unit basis without reconfiguring. ... Northeastern University

05/24/18 / #20180141911

Quinoline derivatives for diagnosis and treatment of alzheimer's disease

A new class of quinoline compounds is useful for the detection and treatment of alzheimer's disease and other neurodegenerative diseases such as amyloidoses and tauopathies. The compounds can be synthesized in radiolabeled form for use as imaging agents, which can be used for early detection of aggregates in the brain or other tissues prior to onset of symptoms, allowing early therapeutic intervention. ... Northeastern University

05/17/18 / #20180135118

Pinhole zero-mode waveguides

Devices and methods useful for sequencing and characterizing single nucleic acid molecules involve large arrays of nanopore zero-mode waveguides (nzmws). The methods and devices are made possible by fabrication of nanoporous membranes of appropriate porosity for use in nucleotide sequencing. ... Northeastern University

05/10/18 / #20180131008

Nitrogen-functionalized platinum-iridium electrocatalyst

The invention provides a nitrogen-functionalized platinum-transition metal catalyst having the formula pt-m-nx/c (where m is a transition element such as fe, co, ni, nb, ta, ir, rh, or ru) for use at the hydrogen electrode of a hydrogen/bromine redox flow battery. The new catalyst possesses excellent activity and durability in the hbr/br2 environment, showing superior resistance to halide poisoning than conventional pt/c or pt-m/c catalysts.. ... Northeastern University

05/10/18 / #20180128693

Stop-start method in a microfluidic calorimeter

A method for calorimetry includes flowing a first fluid through a co-flow reactor microchannel having plural inlets and an outlet, the first fluid flowing through each of the inlets, and measuring transmission of light through a nano hole array (nha) sensor to obtain a baseline extraordinary optical transmission (eot) measurement. The flow of the first fluid is stopped, the microchannel is emptied of the first fluid, and the first fluid and a second fluid are passed through the microchannel such that a reaction occurs, the first fluid flowing through a first of the inlets and the second fluid flowing through a second of the inlets. ... Northeastern University

05/10/18 / #20180125798

Compounds and methods for modulating serotonin receptors in the periphery

This invention relates to, in part, compositions and methods that are useful for, inter alia, the treatment of various diseases, including those linked to binding at a serotonin receptor in the gi tract.. . ... Northeastern University

05/03/18 / #20180117071

Cationic polymers as co-drugs for chemotherapeutic agents

A method for treating a biological cell is disclosed. The method administers a mixture of a chemotherapeutic drug and a co-drug that facilitates delivery of the chemotherapeutic drug to the nucleus of the cell. ... Northeastern University

04/05/18 / #20180097499

Nano- and microelectromechanical resonators

A resonator includes a piezoelectric plate and interdigitated electrode(s). The interdigitated electrode includes a plurality of conductive strips disposed over a top surface of the piezoelectric plate. ... Northeastern University

03/15/18 / #20180071739

Platform for liquid droplet formation and isolation

Embodiments are directed to a platform for liquid droplet generation and isolation for biochemical sensing and testing. An embodiment includes generator, fluid-exchange, and manipulator structures that are vertically aligned on a substrate to form a collection chamber. ... Northeastern University

02/08/18 / #20180038815

Nanotube-based biosensor for pathogen detection

A simple and highly sensitive single walled carbon nanotube (swnt) sensor is provided for detection of a variety of analytes, including small molecules, macromolecules, and pathogens. The high sensitivity, specificity, stability, and rapid operation of the sensor render it useful for detection and quantification of low level contaminants such as pharmaceuticals and pathogens in environmental samples, including wastewater and natural bodies of water.. ... Northeastern University

02/08/18 / #20180038001

Low noise ultrathin freestanding membranes composed of atomically-thin 2d materials

The invention provides methods for direct growth of low noise, atomically thin freestanding membranes of two-dimensional monocrystalline or polycrystalline materials, such as transition metal chalcogenides including molybdenum disulfide. The freestanding membranes are directly grown over an aperture by reacting two precursors in a chemical vapor deposition process carried out at atmospheric pressure. ... Northeastern University

02/08/18 / #20180037924

Nanofluidic device for isolating, growing, and characterizing microbial cells

Nanofluidic devices and methods of the invention are capable of autonomously isolating individual microbial cells using constrictive channels and growing monocultures of the cells for automated characterization of their biochemical properties and interactions with mammalian cells. Single microbial cells, such as bacterial cells, are isolated directly from environmental sources and cultured using chemical factors from their native environment.. ... Northeastern University

02/08/18 / #20180036237

Oil/surfactant mixtures for self-emulsification

Oil-in-water emulsions with small droplet sizes can be formed without requiring either microfluidisation or heating to cause phase inversion, but rather by simple mixing of a pre-mixed composition of oil and surfactant with aqueous material. The oil/surfactant compositions can be mixed with an excess volume of aqueous material to spontaneously form an oil-in-water emulsion with droplets having a diameter<250 nm which shows good adjuvant activity. ... Northeastern University

02/01/18 / #20180028442

Nanoemulsion compositions of taxoid drugs, and methods for the use thereof to target cancer cells and cancer stem cells

A composition of an omega-3 polyunsaturated fatty acid (pufa)-taxoid conjugate encapsulated in an oil-in-water nanoemulsion (ne) drug delivery system. A method of treating cancer by administering an effective amount of a pharmaceutical composition including a pufa-taxoid conjugate encapsulated in an oil-in-water ne drug delivery system to a subject in need of treatment, and treating cancer. ... Northeastern University

01/25/18 / #20180027077

Software-defined implantable ultrasonic device for use in the internet of medical things

Implantable and wearable devices and system for transmitting signals ultrasonically through biological tissue are implemented based on an internet of medical things (iomt) platform software and hardware architecture. The devices are size-, energy-, and resource-constrained and implement ultrasonic communication protocols and communicate with each other through ultrasound.. ... Northeastern University

01/25/18 / #20180024123

Cationic tags for attomole level detection of analytes by mass spectrometry

The invention provides methods of detecting an analyte by multi-stage mass spectrometry with improved s/n ratio. An analyte is labeled with a positively-charged mass tag to form a precursor ion that leads by anchimeric assistance to a greatly enhanced, analyte-characteristic first product ion that can, in turn, lead to a greatly enhanced, analyte-characteristic second product ion in a mass spectrometer. ... Northeastern University

01/18/18 / #20180016157

Mo-doped cozz-type ferrite composite material for use ultra-high frequency

A co2z hexaferrite composition is provided containing molybdenum and one or both of barium and strontium, having the formula (ba2sr(3-z)co(2+x))moxfe(y-2x)o41 where x=0.01 to 0.20; y=20 to 24; and z=0 to 3. The composition can exhibit high permeabilities and equal or substantially equal values of permeability and permittivity while retaining low magnetic and dielectric loss tangents and loss factors. ... Northeastern University

01/04/18 / #20180000344

Internet-linked ultrasonic network for medical devices

A system and method is provided for transmitting signals ultrasonically among a network of implantable and wearable biological devices. The devices includes one or more implantable nodes, which include a sensing and/or actuating unit, at least one gateway node, and at least one access point node. ... Northeastern University

12/28/17 / #20170373647

Linearity enhancement method for low-power low-noise amplifiers biased in the subthreshold region

An amplifier and corresponding method include a field-effect transistor (fet) amplifier and a cascode fet. Each fet may operate with a positive ratio between its third-order nonlinearity coefficient and its linear gain. ... Northeastern University

12/28/17 / #20170367578

Ultrasonic network for wearable devices

An ultrasonic communication system and method provide a networking framework for wearable devices based on ultrasonic communications. The ultrasonic communication system and method incorporate a set of physical, data link, network and application layer functionalities that can flexibly adapt to application and system requirements to efficiently distribute information between ultrasonic wearable devices.. ... Northeastern University

12/21/17 / #20170360986

Collagenous tissue repair device

Methods and devices for tissue remodeling and repair of collagenous tissues, including tendons, ligaments, and bone, as well as scalable connective tissue manufacturing, are provided. Collagen fibers are assembled by extensional strain-induced flow crystallization of collagen monomers. ... Northeastern University

11/30/17 / #20170346466

Impedance calibration device for semiconductor device

An impedance calibration device for a semiconductor device includes a process sensor that detects a process condition for the semiconductor device and outputs a process signal, a temperature monitoring sensor that detects a temperature of the semiconductor device and outputs a temperature signal, a converter that converts the process signal and the temperature signal into a digital signal, and a code generation circuit that generates and outputs a driving code for controlling a level of a voltage at an output node according to the digital signal of the converter and a data signal. The impedance calibration device further includes an output driver that pulls up or pulls down the voltage at the output node according to the driving code.. ... Northeastern University

11/23/17 / #20170338732

Power conversion devices and control methods therefor

Power conversion devices with control algorithms that can solve the double frequency harmonic problem are provided, as are techniques for controlling power converters when the instantaneous values of input and output power are not the same.. . ... Northeastern University

11/16/17 / #20170331450

Nano- and micro-electromechanical resonators

A resonator including a piezoelectric plate and an interdigital electrode is provided. A ratio between a thickness of the plate and a pitch of the interdigital electrode may be from about 0.5 to about 1.5. ... Northeastern University

10/05/17 / #20170284945

Characterization of dielectric slabs attached to the body using focused millimeter waves

A system for characterizing a dielectric object situated adjacent to an electrically conductive surface comprises a radiation source configured to radiate electromagnetic energy toward the dielectric object, and a receiver configured to receive scattered electromagnetic energy scattered by the dielectric object and the electrically conductive surface. The system may further comprise a control subsystem, coupled to the radiation source and the receiver, that determines an apparent focal point within the object, determines a phase shift associated with the scattered electromagnetic energy with respect to the electromagnetic energy radiated by the radiation source, and determine a thickness and an index of refraction of the object based, on the apparent focal point and the phase shift. ... Northeastern University

09/28/17 / #20170279571

Ultrasonic multiplexing network for implantable medical devices

A system and method for transmitting data ultrasonically through biological tissue employs a network of a plurality of nodes, at least a portion of the nodes implantable within the biological tissue. At least one implanted node includes a transmitter having an orthogonal frequency division multiplex signal generator to encode an ultrasonic signal for transmission through the biological tissue to an ultrasonic receiver at another node.. ... Northeastern University

09/21/17 / #20170270254

Methods and systems for quantifying closeness of two sets of nodes in a network

Network-based relative proximity measures according to the present invention quantify the closeness between any two sets of nodes (e.g., drug targets and disease genes in a biological network, or groups of people in a social network). The proximity takes into account the scale-free nature of real-world networks and corrects for degree-bias (i.e., due to incompleteness or study biases) by incorporating various distance definitions between the two sets of nodes and comparison of these distances to those of randomly selected nodes in the network (i.e., the distance relative to random expectation), therefore improving processing of the network data. ... Northeastern University

09/14/17 / #20170261494

Disposable single cell array for personalized diagnostics

Paper-based single cell arrays are provided, as well as methods of making and using the arrays. The invention provides a low cost, high-throughput platform to detect and quantify different types of dna damage at point-of-care without expensive equipment or highly trained personnel. ... Northeastern University

09/14/17 / #20170261264

Fault diagnosis device based on common information and special information of running video information for electric-arc furnace and method thereof

A fault diagnosis method for an electrical fused magnesia furnace includes steps of: 1) arranging six cameras; 2) obtaining video information by the six cameras and sending the video information to a control center; then analyzing the video information by a chip of the control center; wherein a multi-view-based fault diagnosis method is used by the chip, comprising steps of: 2-1) comparing a difference between two consecutive frame histograms for shots segmentation; 2-2) computing a set of characteristic values for each shot obtained by the step 2-1), and then computing color, texture, and motion vector information; finally, evaluating shot importance via entropy; 2-3) clustering shots together by calculating similarity; 2-4) generating and optimizing a multi-view video summarization with a multi-objective optimization model; and 2-5) providing fault detection and diagnosis; and 3) displaying results of the fault detection and diagnosis on a host computer inter face of the control center.. . ... Northeastern University

08/31/17 / #20170247739

Diagnostic system and process for rapid bacterial infection diagnosis

Methods and devices for monitoring the viability of a biofilm comprising pseudomonas aeruginosa bacteria are provided by detecting pyocyanin. The invention relates to electrochemical methods and devices that offer a simple and inexpensive alternative for immediate identification of bacterial infection due to the presence of pseudomonas aeruginosa. ... Northeastern University

08/31/17 / #20170247652

Device and method for high throughput bacterial isolation

Devices and methods for isolating and characterizing microbial cells from an environment are provided. The devices integrate sub-micron constrictions in a nanofluidic device with a standard microtiter plate format to facilitate the high throughput isolation, culturing, analysis, and screening of bacteria and other microbial cells in natural and man-made environments, particularly environments containing microbes adhered on particulate matter.. ... Northeastern University

08/31/17 / #20170247387

Urea/carbamates faah magl or dual faah/magl inhibitors and uses thereof

Disclosed are compounds that may be used to inhibit the action of fatty acid amide hydrolase (faah), monoacylglycerol lipase (magl) or dual faah/magl.. . ... Northeastern University

08/17/17 / #20170236000

Method of extracting feature of image to recognize object

A method of converting a vector corresponding to an input image includes receiving input vector data associated with an input image including an object; and converting the received input vector data into feature data based on a projection matrix having a fixed rank, wherein a first dimension of the input vector data is higher than a second dimension of the feature data.. . ... Northeastern University

08/03/17 / #20170222220

Carbon nanotube-based lithium ion battery

An electrode architecture for lithium ion batteries provides cooling of the bulk electrode during room temperature to high temperature (e.g., 50° c.-80° c.) battery operation. The battery electrode architecture includes alternating layers of lithium ion active material and current collection layers containing with interconnections between current collection layers. ... Northeastern University

07/27/17 / #20170213628

Co2 z-type ferrite composite material for use in ultra-high frequency antennas

A ferrite composition is provided containing ba, co, and ir and having a z-type hexaferrite phase and a y-type hexaferrite phase. The ferrite composition has the formula ba3co(2-x)irxfe(24-2x)o41 where x=0.05-0.20. ... Northeastern University

07/27/17 / #20170210728

Cannabinergic nitrate esters and related analogs

The present technology relates to novel cannabinergic nitrate esters and related analogs, process of preparation, pharmaceutical compositions and their methods of use as medicaments, pharmacological tools and/or biomarkers. The novel cannabinergic nitrate ester compounds provide medicaments useful in treating a variety of diseases and medical disorders.. ... Northeastern University

07/20/17 / #20170202783

Amphiphilic peptide nanoparticles for use as hydrophobic drug carriers and antibacterial agents

Nanoparticulate carrier formulations are useful to solubilize, deliver, and target hydrophobic drugs for treating diseases including cancer and bacterial infections. The formulations contain amphiphilic peptides having a hydrophobic portion and a positively charged hydrophilic portion. ... Northeastern University

07/13/17 / #20170201154

Gear stabilization techniques

A balanced planetary gearbox including an assembly having an input stage and an output stage. The assembly includes two grounds, each with ground rollers and ground rings. ... Northeastern University

07/13/17 / #20170199173

Microfluidic device and method for analysis of tumor cell microenvironments

A microfluidic device provides high throughput generation and analysis of defined three-dimensional cell spheroids with controlled geometry, size, and cell composition. The cell spheroids of the invention mimic tumor microenvironments, including pathophysiological gradients, cell composition, and heterogeneity of the tumor mass mimicking the resistance to drug penetration providing more realistic drug response. ... Northeastern University

07/13/17 / #20170197918

Allosteric modulators of cb1 cannabinoid receptors

The present invention relates to novel heterocyclic derivatives which are allosteric modulators of cannabinoid receptor 1 (cb1) and which are useful for the treatment or prevention of neurological and psychiatric disorders associated with endocannabinoid dysfunction and diseases in which the cb1 subtype of cannabinoid receptor is involved; to processes for their preparation; to pharmaceutical compositions comprising them; and to methods of using them.. . ... Northeastern University

06/29/17 / #20170187347

Piezoelectric mems resonator with integrated phase change material switches

A monolithic integration of phase change material (pcm) switches with a mems resonator is provided to implement switching and reconfiguration functionalities. Mems resonator includes a piezoelectric material to control terminal connections to the electrodes. ... Northeastern University

06/29/17 / #20170183760

Method for smelting magnesium quickly and continuously

A method for smelting magnesium quickly and continuously includes: preparing dolomite or magnesite with reductants and fluorite at a predetermined ratio, uniformly mixing the prepared ingredients to obtain pellets, and calcining the obtained pellets in an argon or nitrogen atmosphere; continuously feeding the high-temperature calcined pellets (without being cooled) under argon protection into a reduction furnace, and performing a high-temperature reduction reaction in a flowing argon atmosphere to obtain high-temperature magnesium steam; and enabling the high-temperature magnesium steam to be carried out of the high-temperature reduction furnace by an argon flow, and performing condensation to obtain metal magnesium. The present invention eliminates a vacuum system and a vacuum reduction tank, so that quick and continuous production of the metal magnesium is realized, the reduction time is shortened to 90 min or less, and the recovery rate of magnesium is increased to 88% or more.. ... Northeastern University

06/29/17 / #20170181971

Nanoparticle- and drug-containing polymersomes for medical applications

Provided are polymersomes for co-delivery of hydrophobic metallic nanoparticles and pharmaceutical agents and suspensions of such polymersomes. Also provided are methods of making such polymersomes and suspensions of polymersome and methods of using the same to treat diseases or conditions.. ... Northeastern University

06/29/17 / #20170181634

Mechanical palpation for subsurface sensing device

The present disclosure provides systems, methods and components of a mechanical palpation sensing device system. The mechanical palpation sensing device includes a plurality of probe tips. ... Northeastern University

06/22/17 / #20170176640

System for multivariate climate change forecasting with uncertainty quantification

A system and method for providing multivariate climate change forecasting are provided that obtain, from one or more climate model datasets, simulated historical and future climate model data, and from one or more climate observational datasets, historical observed climate data. A statistical distribution, using a bayesian model, is provided of extremes or climate indices for one or more variable climate features using the simulated climate model data and the observed climate data. ... Northeastern University

06/22/17 / #20170173893

Magnetic field alignment of emulsions to produce porous articles

The use of magnetic fields in the production of porous articles is generally described. Certain embodiments are related to methods of producing porous articles in which magnetic fields are applied to an emulsion to align emulsion droplets. ... Northeastern University

06/15/17 / #20170170803

Nano- and microelectromechanical resonators

A resonator includes a piezoelectric plate and interdigitated electrode(s). The interdigitated electrode includes a plurality of conductive strips disposed over a top surface of the piezoelectric plate. ... Northeastern University

06/15/17 / #20170169946

Method of engineering single phase magnetoelectric hexaferrite films

A method of making a ferrite thin film is provided in which a portion of the iron ions in the ferrite are substituted by ions of at least one other metal. The substituting ions occupy both tetrahedral and octahedral sites in the unit cell of the ferrite crystal. ... Northeastern University

06/15/17 / #20170165380

Nanosensor compositions and methods of use thereof

Disclosed are compositions comprising a plastic polymer core, a shell surrounding the plastic polymer core, a ligand comprising a binding moiety, an enzyme capable of catalyzing the hydrolysis of a target compound, and a contrast agent, as well as methods of use of such compositions.. . ... Northeastern University

06/08/17 / #20170163240

Nano- and micro-electromechanical resonators

A resonator including a piezoelectric plate and an interdigital electrode is provided. A ratio between a thickness of the plate and a pitch of the interdigital electrode may be from about 0.5 to about 1.5. ... Northeastern University

05/18/17 / #20170136699

Additive manufacturing of discontinuous fiber composites using magnetic fields

A method and apparatus for producing a composite part are provided to enable composite parts to be assembled with precise control over the orientation and spatial distribution of reinforcing or other particles within a matrix material. The method and apparatus use magnetic fields applied during various additive manufacturing processes to achieve complex particles orientations within each layer of the part. ... Northeastern University

05/04/17 / #20170125807

Layered metal oxide cathode material for lithium ion batteries

The invention provides a cathode material for l1-ion batteries. The material has the formula of 0.5li2mno3-0.5lim-n0.5ni0.35co0.15o2. ... Northeastern University

04/27/17 / #20170115114

Roaming mobile sensor platform for collecting geo-referenced data and creating thematic maps

A roaming sensor system collects data on the condition of roads and bridge decks and identifies and maps defects, including cracks, potholes, debonding, tracking, delamination, surface ice, surface water, and rebar corrosion. Data are collected by a vehicle or a fleet of vehicles driven at normal traffic speeds. ... Northeastern University

04/27/17 / #20170114050

N-acylethanolamine hydrolyzing acid amidase (naaa) inhibitors and their use thereof

A compound is represented as formula i, a tautomer thereof, a stereoisomer thereof, or a pharmaceutically acceptable salt thereof. Compounds of formula i are inhibitors of n-acylethanolamine hydrolyzing acid amidase (naaa). ... Northeastern University

04/27/17 / #20170112962

Modified surfaces for attachment of biological materials

The invention relates to bioactive surface coatings deposited on selected substrates. Surface nanostructured film coatings deposited on most metal or nonmetal substrates to provide surfaces can be engineered to promote enhanced tissue/cell adhesion. ... Northeastern University

04/13/17 / #20170102263

Zero power sensors

An environmental physical sensor is provided that includes a power input terminal, a sensor output terminal, and a resonant switch. The resonant switch includes a mechanical element that is responsive to an environmental stimulus and is coupled to an electrical switch. ... Northeastern University

04/06/17 / #20170098760

Transition metal dichalcogenide-based spintronics devices

Transition metal dichalcogenide (tmd)-based spintronics devices, each including a tmd thin film layer, a first gate electrode, a first insulating layer sandwiched between the tmd thin film layer and the first gate electrode, a second gate electrode, and a second insulating layer sandwiched between the tmd thin film layer and the second gate electrode. Such a device, when also including a source electrode and a drain electrode, functions as a spin filter. ... Northeastern University

03/30/17 / #20170087192

Methods for growth and maturation of ovarian follicles

The present technology provides for methods for generation and isolation of granulosa cells and/or granulosa cell precursors from multi-potent cells, wherein the granulosa cells and/or granulosa cell precursors are useful in methods for growth and maturation of follicles or follicle-like structures. Additionally, the present technology also provides for methods of increasing steroidal hormones in a subject in need thereof.. ... Northeastern University

03/23/17 / #20170081273

Serotonin receptor-targeting compounds and methods

This invention relates to, in part, compositions and methods that are useful for, inter alia, the treatment of various diseases, including those linked to binding at a serotonin receptor. The compositions include chiral tetrahydronaphthalen-2-amine derivatives. ... Northeastern University

03/16/17 / #20170076474

System for beauty, cosmetic, and fashion analysis

A system and method are provided to detect, analyze and digitally remove makeup from an image of a face. An autoencoder-based framework is provided to extract attractiveness-aware features to perform an assessment of facial beauty.. ... Northeastern University

03/02/17 / #20170058422

High rate electric field driven nanoelement assembly on an insulated surface

A method for high rate assembly of nanoelements into two-dimensional void patterns on a non-conductive substrate surface utilizes an applied electric field to stabilize against forces resulting from pulling the substrate through the surface of a nanoelement suspension. The electric field contours emanating from a conductive layer in the substrate, covered by an insulating layer, are modified by a patterned photoresist layer, resulting in an increased driving force for nanoelements to migrate from a liquid suspension to voids on a patterned substrate having a non-conductive surface. ... Northeastern University

03/02/17 / #20170058336

Fluorescence-based analysis of biopolymers using nanopores

Described herein are systems for analysis of biopolymers and complexes containing biopolymers based on optical measurement of ion flux through pores. Also described are methods of using such devices for analysis of biopolymers and complexes containing biopolymers, including methods of determining the nucleotide sequences of polynucleotides.. ... Northeastern University

03/02/17 / #20170056944

Cooling method and on-line cooling system for controlled rolling with inter-pass cooling process

The present invention relates to controlled cooling in manufacture of steel plate, and in particular, to an on-line cooling system for controlled rolling with an inter-pass cooling process, which comprises a rolling mill and on-line cooling equipment. The cooling equipment is accessorily arranged on the exit of the rolling mill, so that the rolling mill and the cooling equipment are combined. ... Northeastern University

02/09/17 / #20170040473

Nanostructured hybrid-ferrite photoferroelectric device

A photovoltaic device is fabricated using nanostructured hybrid ferrite materials with interdigital electrodes. The device includes ferrimagnetic ferrite nanopartides having a tunable narrow bandgap of 2.5 ev or less, which are deposited onto a thin ferroelectric film. ... Northeastern University

02/09/17 / #20170036920

A method for recovering alkali and aluminum in course of treatment of bayer red mud by using calcification-carbonation method

A method for recovering alkali and aluminum during treatment of bayer red mud using a calcification-carbonation method, including steps of mixing the bayer red mud with calcium aluminate or with calcium aluminate and lime, performing calcification dealkalization conversion in a high-concentration alkaline liquor, and carbonizing the calcified residues produced during dealkalization to obtain carbonized residues; and then performing low-temperature aluminum dissolution, aluminum precipitation and the like to obtain calcium aluminate products, which is returned to the calcification dealkalization conversion of the red mud for recycling. Part of an alkali-containing and aluminum-containing liquid phase after calcification dealkalization conversion can be used as supplementary alkali in the bayer production course for recycling. ... Northeastern University

01/26/17 / #20170020900

Methods for screening antimicrobial and antiviral compounds and uses thereof

The invention features compounds that have antibacterial activity, their use for the treatment of bacterial infections, screening methods that use whole animals or plant seedlings to identify compounds that inhibit a pathogen in the animal or plant, and screening methods to identify compounds that increase the lifespan of an organism.. . ... Northeastern University

01/12/17 / #20170009365

Damascene template for directed assembly and transfer of nanoelements

Damascene templates have two-dimensionally patterned raised metal features disposed on an underlying conductive layer extending across a substrate. The templates are topographically flat overall, and the patterned conductive features establish micron-scale and nanometer-scale patterns for the assembly of nanoelements into nanoscale circuits and sensors. ... Northeastern University

01/05/17 / #20170003594

Elastomer-assisted manufacturing

Methods of performing lithography in films attached to elastomeric substrates are provided, including methods of performing optical lithography using photoresist films on a stretched elastomeric substrate. Also described are flexible electronic devices made by the methods, and patterned substrates having small voids fabricated by the methods.. ... Northeastern University

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