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Old Dominion University Research Foundation patents


Recent patent applications related to Old Dominion University Research Foundation. Old Dominion University Research Foundation is listed as an Agent/Assignee. Note: Old Dominion University Research Foundation may have other listings under different names/spellings. We're not affiliated with Old Dominion University Research Foundation, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "O" | Old Dominion University Research Foundation-related inventors


Electroporation-induced electrosensitization

Methods of enhancing membrane permeabilization in a cell are provided. A method includes disposing the cell between a first electrode and a second electrode and applying a plurality of electrical pulses between the first electrode and the second electrode. ... Old Dominion University Research Foundation

Nanosecond pulsed electric fields cause melanomas to self-destruct

Methods for a new, drug-free therapy for treating solid skin tumors through the application of nanosecond pulsed electric fields (“nspefs”) are provided. In one embodiment of the invention, the cells are melanoma cells, and the applied nspefs penetrate into the interior of tumor cells and cause tumor cell nuclei to rapidly shrink and tumor blood flow to stop. ... Old Dominion University Research Foundation

Ablation of myocardial tissues with nanosecond pulsed electric fields

An apparatus and methods for performing ablation of myocardial tissues are disclosed. The apparatus includes a plurality of ablation electrode configurations to which nanosecond pulsed electric fields are applied. ... Old Dominion University Research Foundation

Methods and devices for treatment of tumors with nano-pulse stimulation

Disclosed herein are methods and devices for stimulating an immune response to a disease in a subject, which involves passing sub-microsecond long pulses of electric fields having an amplitude between 5 kv/cm and 68 kv/cm through an abnormal growth of a subject sufficient to suppress myeloid-derived suppressor cell (mdsc) or regulatory t cell (treg) production, increase adenosine triphosphate (atp) or high mobility group box 1 (hmgb1) production, or stimulate dendritic cell activation in the subject.. . ... Old Dominion University Research Foundation

Multi-electrode electrical pulse delivery system for treatment of biological tissues

Systems and methods for treating or manipulating biological tissues are provided. In the systems and methods, a biological tissue is placed in contact with an array of electrodes. ... Old Dominion University Research Foundation

Low-energy defibrillation with nanosecond pulsed electric fields

Methods for terminating fibrillation in a fibrillating heart employing nanosecond pulsed electric fields (nspefs) are disclosed. Nspef defibrillation demonstrates its effectiveness as a new defibrillation modality, achieving reliable defibrillation with energies that are an order of magnitude lower than those needed for conventional defibrillation (millisecond shocks with mono- and bi-phasic waveforms). ... Old Dominion University Research Foundation

Apparatus for generating electrical pulses and methods of using the same

A method and apparatus are provided for delivering an agent into a cell through the application of nanosecond pulse electric fields (“nspef's”). The method includes circuitry for delivery of an agent into a cell via known methods followed by the application of nanosecond pulse electric fields to said cell in order to facilitate entry of the agent into the nucleus of the cell. ... Old Dominion University Research Foundation

System and methods of treatment using electromagnetic illumination

A method of inducing local cell death in patient tissue is provided. The method includes generating first and second radiation, conveying the radiation to a focusing element, and focusing the radiation on a target with the focusing element. ... Old Dominion University Research Foundation

Treatment of biological tissues using subnanosecond electric pulses

A system for treatment of biological tissues is provided. The system includes a lens having a hollow, substantially hemispherical shape with an outer surface and an inner surface, the inner surface defining a substantially hemispherical cavity for inserting the biological tissues. ... Old Dominion University Research Foundation

Expandable catheter devices electrode array

Catheter devices can include an elongate housing extending along a major axis, the elongate housing comprising a first end an opening. The catheter devices can also include an electrode assembly disposed in the elongate housing and including deformable electrodes with respective electrode distal ends, where the electrode distal ends each consist of respective member portions and respective tip portions. ... Old Dominion University Research Foundation








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