Organovo Inc patents (2017 archive)

Automated devices, systems, and methods for the fabrication of tissue

Described herein are improvements to bioprinting technology that facilitate automation of tissue and organ fabrication processes.. . ... Organovo Inc

Engineered renal tissues, arrays thereof, and methods of making the same

Disclosed are renal tissues and arrays thereof that include a layer of renal interstitial tissue, the renal interstitial tissue comprising renal fibroblasts and endothelial cells; and a layer of renal epithelial tissue, the renal epithelial tissue comprising renal tubular epithelial cells, the renal epithelial tissue in contact with the layer of renal interstitial tissue to form a three-dimensional, engineered, biological renal tissue. Also disclosed are methods of fabricating and using the same.. ... Organovo Inc

Methods for tissue fabrication

Disclosed herein are improved methods for fabricating bioprinted, three-dimensional, biological tissues. The methods relate to exposures to low temperatures, incubations at low temperatures of various durations, and fabrication in environments without structural cross-linking treatments.. ... Organovo Inc

Devices, systems, and methods for the fabrication of tissue utilizing uv cross-linking

Described herein are bioprinters comprising: one or more printer heads, wherein a printer head comprises a means for receiving and holding at least one cartridge, and wherein said cartridge comprises contents selected from one or more of: bio-ink, and support material; a uv light module for optionally exposing the contents of at least one cartridge to uv light; a means for calibrating the position of at least one cartridge; and a means for dispensing the contents of at least one cartridge. Also described herein are methods of using and bioprinting cartridges for such bioprinters.. ... Organovo Inc