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Oxford University Innovation Limited patents


Recent patent applications related to Oxford University Innovation Limited. Oxford University Innovation Limited is listed as an Agent/Assignee. Note: Oxford University Innovation Limited may have other listings under different names/spellings. We're not affiliated with Oxford University Innovation Limited, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "O" | Oxford University Innovation Limited-related inventors


A nickel-based alloy

A nickel-based alloy composition consisting, in weight percent, of: between 12.3 and 15.2% chromium, between 4.8 and 12.0% cobalt, between 2.5 and 8.3% tungsten, between 0.0 and 0.5% molybdenum, between 0.0 and 0.5% rhenium, between 3.5 and 6.7% aluminium, between 6.1 and 10.7% tantalum, between 0.0 and up to 0.5% hafnium, between 0.0 and 0.5% niobium, between 0.0 and 0.5% titanium, between 0.0 and 0.5% vanadium, between 0.0 and 0.1% silicon, between 0.0 and 0.1% yttrium, between 0.0 and 0.1% lanthanum, between 0.0 and 0.1% cerium, between 0.0 and 0.003% sulphur, between 0.0 and 0.05% manganese, between 0.0 and 0.05% zirconium, between 0.0 and 0.005% boron, between 0.0 and 0.01% carbon, the balance being nickel and incidental impurities.. . ... Oxford University Innovation Limited

Dengue vaccines

The invention relates to a protein comprising a plurality of conserved peptide sequences, or variants thereof, wherein at least one of the conserved sequences is conserved across all four dengue virus serotypes denv-1, denv-2, denv-3 and denv-4, and wherein the conserved sequences comprise at least part of a sequence of one or more non-structural proteins of the dengue virus serotypes. The invention further relates to associated peptides, compositions, nucleic acids, viral vectors, virus-like particles, use, prime boost vaccination kits, agents and methods.. ... Oxford University Innovation Limited

Beverage composition comprising nanoencapsulated oxygen

The invention relates to a beverage composition comprising: water; oxygen bubbles; a surfactant in an amount of between about 0.1% (v/v) and about 0.5% (v/v); one or more viscosity modifying agent(s) in an amount of between about 0.5% (v/v) and about 2.5% (v/v); and optionally citric acid in an amount of between about 0.1% (v/v) and about 0.5% (v/v). The invention further relates to compositions, methods of treatment for cancer, the composition for use in treatment of cancer, and the manufacture of the composition.. ... Oxford University Innovation Limited

Method for trapping vacancies in a crystal lattice

There is provided a method of fabricating a trapped vacancy in a crystal lattice of a target comprising: positioning the target in a laser system, the target containing vacancy trapping elements within the crystal lattice; modifying the crystal lattice within the target by using a laser to generate a lattice vacancy; and annealing the target to cause the lattice vacancy to migrate and be captured by a vacancy trapping element to form the trapped vacancy in the crystal lattice.. . ... Oxford University Innovation Limited

Contrast agent for imaging hypoxia

The invention relates to a conjugate which comprises an mri contrast agent component comprising a nanoparticle, which nanoparticle comprises a metal or a metal compound, and a hypoxia targeting moiety which is conjugated to the mri contrast agent component, especially wherein said nanoparticle comprises iron oxide and a biocompatible coating and wherein said hypoxia targeting moiety is a nitroimidazole. Also provided is the use of a said conjugate in a method of imaging a subject, a method of de-testing hypoxia, and a method of evaluating the activity of a pharmaceutical. ... Oxford University Innovation Limited

Characterisation of dynamical physical systems

A dynamical physical system of particles represented by input data representing the phase space state of the particles over time is characterised by deriving a feature vector in respect of each particle comprising plural metrics that each describe a change in the phase space state of the particle over time. A classification of particles into plural classes is performed by applying a machine learning technique that operates on the feature vectors of the particles, and outputting classification data representing the classification.. ... Oxford University Innovation Limited

Method for diagnosing a brain tumour in a human

An in vitro method for diagnosing a brain tumour in a human test subject comprising: determining the concentration of at least two metabolites comprised in a biofluid sample obtained from the human test subject; comparing the concentration of the at least two metabolites in the biofluid sample with the concentration of the same at least two metabolites in at least one reference standard obtained from a non-tumour bearing subject and/or a tumour bearing subject; and identifying a concentration difference for each of the at least two metabolites in the biofluid sample relative to the reference standard; wherein the concentration difference for each of the at least two metabolites in the biofluid sample correlates with the presence of a brain tumour. The invention also relates to a data-storage medium comprising data obtained by a method of the invention.. ... Oxford University Innovation Limited

Computer-aided tracking and motion analysis with ultrasound for measuring joint kinematics

Disclosed are various embodiments for computer-aided tracking and motion analysis with ultrasound. A computing device is employed to access an ultrasound video generated by at least one ultrasonic imaging device and/or at least one motion sensing camera. ... Oxford University Innovation Limited

Method and apparatus for vital signs measurement

A method of monitoring changes in oxygen saturation of a subject by analysing a three colour channel video image of the exposed skin of the subject. Within each colour channel a normalised signal obtained by dividing the intensity signal by its mean value, and the normalised signals are averaged across plural regions of interest within the exposed skin area image of the subject. ... Oxford University Innovation Limited

Mutant enzymes

This invention relates to mutant enzymes with enhanced properties and processes for oxidation of organic compound substrates using such enzymes.. . ... Oxford University Innovation Limited

Method for treatment and prognosis of colorectal cancer

The invention relates to the treatment and prognosis of colorectal cancer, especially proximal colorectal cancer. It also relates to identifying patients with colorectal cancer who are likely to respond to therapy with an inhibitor of interleukin 22 signalling.. ... Oxford University Innovation Limited

A method of detecting objects within a 3d environment

A method and system for detecting objects within a three-dimensional (3d) environment, comprising obtaining a 3d point-cloud representation of the environment, the point-cloud comprising a set of point locations, and converting the point-cloud to a 3d feature grid, wherein converting the point-cloud to the 3d feature grid comprises discretising the 3d space into cells according to a grid size; determining which cells contain points from the 3d point-cloud; and mapping any that do to a feature vector; and mapping any that do not to a zero feature vector. The method further comprises generating a detection window sized to contain an integral number of the cells and having a set of positions which can be occupied; calculating a detection score for each of the positions by: casting a vote for each cell within the detection window into which at least one point falls, wherein each vote is calculated using the feature vector of the cell and a weighting vector; and summing the votes, and determining whether each position contains an object of interest based on the detection score, each detection window with a detection score greater than a threshold being classified as containing an object of interest.. ... Oxford University Innovation Limited

Compact microscope

A compact microscope including an enclosure, a support element, a primary optical support element located within the enclosure and supported by the support element, at least one vibration isolating mount between the support element and the primary optical support element, a sample stage supported on the primary optical support element to support a sample, a return optical system to receive returned light from a sample and transmit returned light to a detection apparatus, wherein the return optical system is mounted on the primary optical support element, and wherein the compact microscope include a at least one of the following elements; a) an objective lens system, b) a temperature-control system, and c) the return optical system being operable to separate returned light into at least a first wavelength band and a second wavelength band.. . ... Oxford University Innovation Limited

Arthroplasty apparatus and method

A femoral trial component (16) for attachment to a prepared distal surface of a femur, the femoral trial component comprising a first fastening point (20) for coupling the femoral trial component to a tibial cutting jig. The femoral trial component may further comprise a second fastening point (21) for coupling the trial component to a tibial cutting jig (25), the first and second fastening points being at a predetermined angle (e.g. ... Oxford University Innovation Limited

05/17/18 / #20180135078

Aav-vectors for use in gene therapy of choroideremia

The present invention relates to gene therapy for treatment or prevention of choroideremia.. . ... Oxford University Innovation Limited

05/17/18 / #20180132801

Patient positioning apparatus

A patient positioning apparatus for use with a medical imaging device, the patient positioning apparatus comprising a first element and a second element, the first element having a base part and an upper part to engage a knee joint of the patient, the second element comprising a lower leg engagement part to receive a lower leg of the patient to maintain the lower leg in a desired position.. . ... Oxford University Innovation Limited

05/10/18 / #20180125796

Treatment of mycobacterial infection

The invention provides a combination comprising a serca antagonist and an inhibitor of glycosphingolipid biosynthesis, for use in the treatment of an infection by a pathogenic mycobacterium. The combination may for instance be used to treat tuberculosis.. ... Oxford University Innovation Limited

04/05/18 / #20180096751

Hydrogel network

The invention provides a hydrogel network comprising a plurality of hydrogel objects, wherein each of said hydrogel objects comprises: a hydrogel body, and an outer layer of amphipathic molecules, on at least part of the surface of the hydrogel body, wherein each of said hydrogel objects contacts another of said hydrogel objects to form an interface between the contacting hydrogel objects. A process for producing the hydrogel networks is also provided. ... Oxford University Innovation Limited

03/22/18 / #20180083213

Optoelectronic devices with organometal perovskites with mixed anions

The invention provides an optoelectronic device comprising a mixed-anion perovskite, wherein the mixed-anion perovskite comprises two or more different anions selected from halide anions and chalcogenide anions. The invention further provides a mixed-halide perovskite of the formula (i) [a][b][x]3 wherein: [a] is at least one organic cation; [b] is at least one divalent metal cation; and [x] is said two or more different halide anions. ... Oxford University Innovation Limited

03/22/18 / #20180082044

Method for designing alloys

A computer assisted method of designing a designed alloy composition comprising a plurality of elements, the method comprising the steps of: populating a multi-dimensional alloy space with a plurality of candidate alloy compositions, the plurality of candidate alloy compositions including for each of the plurality of elements at least three candidate alloy compositions with different amounts of the respective element to each other; performing at least one test on each individual one of the plurality of candidate alloy compositions until each of the individual ones of the plurality of candidate alloy compositions fails a test or has passed all tests; outputting the designed alloy composition based on one or more of the individual ones of the plurality of candidate alloy compositions which have passed all tests, wherein the at least one test includes at least: a phase equilibrium test in which predicted phase equilibrium is determined as a function of elemental composition of the individual one of the plurality of candidate alloy compositions; and at least one merit index test in which a predicted property of the individual one of the plurality of candidate alloy compositions is predicted as a function of the elemental composition of the individual one of the plurality of candidate alloy compositions and failing the individual one of the plurality candidate alloy compositions if the predicted property does not meet a desired predicted property.. . ... Oxford University Innovation Limited

03/22/18 / #20180080081

Dna conformation (loop structures) in normal and abnormal gene expression

Method of detection or diagnosis of abnormal gene expression in an individual comprising determining in a sample from the individual the presence or absence of a chromosome structure in which two separate regions of the gene have been brought into close proximity, to thereby detect or diagnose whether the individual has abnormal gene expression.. . ... Oxford University Innovation Limited

03/08/18 / #20180068756

Transparent electrically - conductive solid material, and method and composition for forming transparent electrically - conductive solid material

A method of preparing a transparent, electrically-conductive solid material is provided, typically a coating. The method comprises: (i) providing a liquid composition comprising a matrix-forming material and a plurality of metal nanowires, and optionally a carrier liquid in which the matrix-forming material and the plurality of metal nanowires may be dispersed; and (ii) forming the solid material from the liquid composition. ... Oxford University Innovation Limited

03/08/18 / #20180066340

A nickel-based alloy

A nickel-based alloy composition consisting, in weight percent, of: between 7.0 and 1.0% chromium, between 4.0 and 14.0% cobalt, between 1.0 and 2.0% rhenium, between 0.5 and 11.0% tungsten, between 0.0 and 0.5% molybdenum, between 4.0 and 6.5% aluminium, between 8.0 and 12.0 tantalum, between 0.0 and up to 0.5% hafnium, between 0.0 and 0.5% niobium, between 0.0 and 0.5% titanium, between 0.0 and 0.5% vanadium, between 0.0 and 0.1% silicon, between 0.0 and 0.1% yttrium, between 0.0 and 0.1% lanthanum, between 0.0 and 0.1% cerium, between 0.0 and 0.003% sulphur, between 0.0 and 0.05% manganese, between 0.0 and 0.05% zirconium, between 0.0 and 0.005% boron, between 0.0 and 0.01% carbon, the balance being nickel and incidental impurities.. . ... Oxford University Innovation Limited

02/15/18 / #20180042992

Treatment of eye disease

. . A method of treating an eye disease comprising administering an adeno-associated virus (aav) vector to a mammalian subject by subretinal injection, wherein the aav vector comprises a nucleotide sequence encoding melanopsin operably linked to an expression control sequence to promote expression of melanopsin in cells of the eye of the subject.. . ... Oxford University Innovation Limited

02/01/18 / #20180028635

Composition and uses thereof

The present invention provides a particle comprising a fusion protein, wherein the fusion protein comprises at least one nanp repeat (seq id no: 7), some or all of the c-terminus of the cs protein from plasmodium falciparum and a hepatitis b surface antigen, and wherein the particle comprises no, or substantially no, free hepatitis b surface antigen protein, and uses thereof.. . ... Oxford University Innovation Limited

02/01/18 / #20180027914

An impact absorbing structure and a helmet comprising such a structure

An impact absorbing structure comprises a unitary material formed as a stretch-dominated hollow cell structure and a helmet comprising such a structure as an inner impact resistant liner.. . ... Oxford University Innovation Limited

01/25/18 / #20180024058

Functional material including metal-organic framework, method of preparing the same, and photochemical sensor including the same

A functional material includes a porous metal-organic framework (mof) including an organic ligand derived from benzenedicarboxylic acid and a metal ion cluster coordination-bonded with the organic ligand, and a luminescent molecule in pores of the mof.. . ... Oxford University Innovation Limited

01/04/18 / #20180000966

Simian adenovirus and hybrid adenoviral vectors

Recombinant adenoviral vectors, immunogenic compositions thereof and their use in medicine, and methods for generating recombinant adenoviral vectors are provided. In particular, the an adenovirus vector having a capsid derived from chimpanzee adenovirus ady25, wherein the capsid encapsidates a nucleic acid molecule comprising an exogeneous nucleotide sequence of interest are provided.. ... Oxford University Innovation Limited

12/28/17 / #20170369433

Beta lactamase inhibitors

A compound which is a thienolate of formula (i) or a pharmaceutically acceptable salt thereof: (i) wherein r1, r3, ring a1, n and ring a2 are as defined herein, are found to be useful in inhibiting metallo-beta-lactamase and therefore in potentiating the activity of beta lactamase antibiotics. The compound can be used alone or in combination with a rhodanine of formula (ii) or a pharmaceutically acceptable salt thereof: (ii) wherein r3, ring a1, n, ring a2, l and ring b are as defined herein. ... Oxford University Innovation Limited

12/21/17 / #20170362558

Biological sample actuator

An apparatus is provided for mechanically loading a biological sample. The apparatus comprises: a container for housing the biological sample; a ferromagnetic element, for attachment to the biological sample within the container; and a solenoid for generating a magnetic field within the container, so as to apply a force to the ferromagnetic element. ... Oxford University Innovation Limited

12/14/17 / #20170354334

Method and apparatus for measuring and displaying a haemodynamic parameter

Haemodynamic parameters such as the amplitude and phase of a pulse wave passing through a region of interest can be obtained from a video image of the exposed skin of a patient by processing of the reflectance photoplethysmographic signal using signal averaging. The region of interest is defined and a reflectance photoplethysmographic signal obtained by finding the mean pixel intensity across the region of interest for each video frame. ... Oxford University Innovation Limited

12/07/17 / #20170350893

Biomarker and therapy intervention for malignancy risk patients

The invention relates to a method of determining an increased risk of cancer in an immunosuppressed patient, the method comprising: (a) determining the percentage of cd8+cd57+ t-cells in a population of cd8+ t-cells in a sample from the patient; wherein a percentage of 40% or greater of cd8+cd57+ t-cells is indicative of an increased risk of cancer; and/or (b) determining the percentage of cd4+cd57+ t-cells in a population of cd4+ t-cells in a sample from the patient; wherein a percentage of 10% or greater of cd4+cd57+ t-cells is indicative of an increased risk of cancer.. . ... Oxford University Innovation Limited

12/07/17 / #20170350841

Detecting composition of a sample based on thermal properties

The invention relates to detecting a composition of a sample or contamination in liquids by detecting corresponding changes in their thermal properties. In a disclosed arrangement, an apparatus is provided comprising a first probe element configured to provide a first surface in direct contact with the sample and a second surface that is not in direct contact with the sample. ... Oxford University Innovation Limited

11/23/17 / #20170332978

Signal processing method and apparatus

A method and apparatus for estimating the frequency of a dominant periodic component in an input signal by modelling the input signal using auto-regressive models of several different orders to generate candidate frequencies for the periodic component, generating synthetic sinusoidal signals of each of the candidate frequencies, and calculating the cross-correlation of the synthetic signals with the original signal. The frequency of whichever of the synthetic signals has the highest cross-correlation with the original signal is taken as the estimate of the frequency for the dominant periodic component of the input signal. ... Oxford University Innovation Limited

10/26/17 / #20170310120

Electrical energy storage device

An electrical energy storage device includes a plurality of energy cell slots for receiving energy cells; and a controller; wherein the controller is arranged to estimate a characteristic of a cell in each slot; and wherein the controller is arranged to apply charge and discharge currents to each cell slot dependent upon at least one estimated characteristic currently associated with that slot. The controller may be a single controller that controls all slots or it may be implemented as multiple controllers each controlling more than one cell slot or a controller for each slot. ... Oxford University Innovation Limited

10/26/17 / #20170307714

Combined angiography and perfusion using radial imaging and arterial spin labeling

The present disclosure is directed to combined angiography and perfusion using radial imaging and arterial spin labeling.. . ... Oxford University Innovation Limited

10/26/17 / #20170307699

Systems and methods for the selective mapping of water t1 relaxation times

Described herein are systems and methods for the selective mapping of water t1 relaxation times.. . ... Oxford University Innovation Limited

09/21/17 / #20170273168

Radio frequency cavities

A radio-frequency (rf) cavity apparatus for accelerating charged particles includes first and second cavity arms. The first and second cavity arms have respective first and second axes of rotational symmetry and each cavity arm includes at least one cell. ... Oxford University Innovation Limited

09/21/17 / #20170265832

Method for characterisation of perivascular tissue

Methods for volumetric characterisation of perivascular adipose tissue use data collected by computed tomography (ct) scanning. The volumetric characterisation of perivascular adipose tissue allows the inflammatory status of underlying blood vessels to be established by ct scanning. ... Oxford University Innovation Limited

08/24/17 / #20170241787

Determining the position of a mobile device in a geographical area

. . A mobile device (100) caried by a user has sensors providing acceleration and orientation information. These are processed to provide trajectory for the device. ... Oxford University Innovation Limited

08/17/17 / #20170233803

Method for sequencing a heteropolymeric target nucleic acid sequence

The invention relates to a method for sequencing a heteropolymeric target nucleic acid sequence that involves stochastic sensing. The invention also relates to a method for improving a pore for sequencing a target nucleic acid sequence by modifying one or more sites in the pore.. ... Oxford University Innovation Limited

08/10/17 / #20170229249

Thin film production

The present invention relates to a process for producing a layer of a crystalline material, which process comprises disposing on a substrate: a first precursor compound comprising a first cation and a sacrificial anion, which first cation is a metal or metalloid cation and which sacrificial anion comprises two or more atoms; and a second precursor compound comprising a second anion and a second cation, which second cation can together with the sacrificial anion form a first volatile compound. The invention also relates to a layer of a crystalline material obtainable by a process according to the invention. ... Oxford University Innovation Limited

08/10/17 / #20170226578

Measurement of analytes with membrane channel molecules, and bilayer arrays

The invention relates to a method for detection of analyte interaction with a channel molecule held in a membrane, comprising the optical detection of a modification in the flux of a signal molecule as it passes through the channel molecule by the action of a membrane potential, wherein the modification in the flux is caused by at least partial blockage of the channel molecule by the analyte. The invention further relates to bilayer arrays, components, methods of manufacture and use.. ... Oxford University Innovation Limited

08/03/17 / #20170216923

Porous materials comprising two-dimensional nanomaterials

According to the present invention, there are provided processes for preparing a porous composite material comprising a metal and a two-dimensional nanomaterial. In one aspect, the processes comprise the steps of: providing a powder comprising metal particles; heating the powder such that the metal particles fuse to form a porous scaffold; and forming a two-dimensional nanomaterial on a surface of the porous scaffold by chemical vapour deposition (cvd). ... Oxford University Innovation Limited

07/27/17 / #20170209558

Treatment and prevention of malaria

. . There are provided antigens, vectors encoding the antigens, and antibodies and other binding compounds to the antigens and uses thereof in the prevention or treatment of malaria. In particular, compositions are provided comprising fragments of reticulocyte-binding protein homologue 5 (pfrh5). ... Oxford University Innovation Limited

07/06/17 / #20170190772

Treatment of lysosomal disorders (il-1 antagonists)

The invention relates to methods for treating a lysosomal storage disease (lsd) in a patient. Kits for use in such methods are also provided.. ... Oxford University Innovation Limited

06/29/17 / #20170182182

Composition for delivery of genetic material

The present invention relates to exosomes, loaded with genetic material and methods of producing them and to the use of such exosomes for delivering genetic material in vivo, in particular the use of such exosomes in methods of gene therapy or gene silencing.. . ... Oxford University Innovation Limited

06/15/17 / #20170165361

Treatment of lysosomal disorders (anti-tnf therapy)

The invention relates to methods for treating a lysosomal storage disease (lsd) in a patient. Kits for use in such methods are also provided.. ... Oxford University Innovation Limited

06/01/17 / #20170153234

Method

The invention relates to methods of determining whether or not an individual has or is likely to develop a neurological disease and related methods and kits.. . ... Oxford University Innovation Limited

05/18/17 / #20170138884

Electrochemical method and apparatus

Herein is disclosed a method for detecting a material comprising a thiol group (e.g. Homocysteine, cysteine, glutathione) in a sample, the method comprising: •providing an electrode comprising a carbon material; •contacting said electrode with said sample in the presence of catechol or more generally a precursor of ortho-quinone; •performing cyclic or square wave voltammetry to convert catechol to ortho-quinone and wherein said ortho-quinone reacts with the material comprising a thiol group to form an electrochemical reaction product.. ... Oxford University Innovation Limited

05/18/17 / #20170137341

Fluorination method

The present invention relates to a process for producing an organic compound comprising an 18f atom. The compounds comprising an 18f can be useful as pet ligands for use in diagnostics and/or scanning. ... Oxford University Innovation Limited

05/11/17 / #20170128099

Apparatus for providing and maintaining access to a surgical site

The invention relates to an apparatus for providing and maintaining access to a surgical site, particularly a surgical site that needs to be accessed through delicate tissue such as brain tissue. The invention relates particularly to an apparatus that uses an expandable member or trochar. ... Oxford University Innovation Limited

04/27/17 / #20170114450

Process for the production of two-dimensional nanomaterials

The present invention provides a process for producing a two-dimensional nanomaterial, the process comprising forming the two-dimensional nanomaterial on a surface of a substrate by cvd, wherein said surface is a liquid surface which comprises a molten eutectic compound. Substrates and substrate precursors for use in said process are also provided.. ... Oxford University Innovation Limited

04/06/17 / #20170098128

Method of locating a sensor and related apparatus

A method of localising a vehicle hosting a sensor comprises capturing data from the sensor providing a sensed scene around the vehicle at a current time, processing the sensed scene to extract a set of features from the sensed scene and determine a position of the vehicle from the sensed scene in relation to a previous position of the sensor, comparing the extracted set of features to one or more stored experiences, wherein each stored experience comprises a plurality of sets of features, where each set of features has been determined from a previously sensed scene, to ascertain whether the sensed scene can be recognised within any of the stored experiences, and if the extracted set of features of the sensed scene are recognised then that stored experience is used to produce an estimate of the position of the vehicle at the current time with respect to the stored experience.. . ... Oxford University Innovation Limited

03/30/17 / #20170090881

Methods and devices for executing program code of a probabilistic programming language

A method, implemented on at least one computing device, for executing program code of a probabilistic programming language. The program code comprises a series of statements including random procedures for which values are determined when the random procedures are executed, and constraints on results obtained when executing the program code. ... Oxford University Innovation Limited

03/30/17 / #20170088876

Assays, methods and means

A novel class of hydroxylases is described having the amino acid sequence of seq id no: 2, 4, 6 and 8, and variants and fragments thereof having hif hydroxylation activity. The polypeptides of the invention have in particular prolyl hydroxylase activity. ... Oxford University Innovation Limited

03/16/17 / #20170076455

Vehicle localization

A method of localising a transportable apparatus (102) within an environment around the apparatus is disclosed. The method comprises obtaining a sequence of images (200) of the environment and generating one or more sequences of transformed images (204) from the sequence of images wherein an image from the sequence of images has undergone a transformation to provide a transformed image within the sequence of transformed images. ... Oxford University Innovation Limited

03/16/17 / #20170074665

Determining the position of a mobile device in a geographical area

A method of determining the position of a mobile device using a model. The model comprises a graph comprising a set of vertices and a set of edges between the vertices, and one or more feature functions that take as input one or more vertices of the graph and a set of observations for the device, and return a feature value. ... Oxford University Innovation Limited

03/16/17 / #20170073765

Method of determining risk of 5-fluorouracil toxicity

The invention provides an assay useful in predicting risk of 5-fluorouracil (fu) toxicity in a subject. The subject may be screened for the presence of at least one tyms polymorphism and/or at least one dpyd polymorphism. ... Oxford University Innovation Limited

02/16/17 / #20170045547

Generating timing signals

The invention relates generating timing signals registering the passage of a component past a sensor. The invention relates particularly to the generation of timing signals in real time for health monitoring of a mechanical system, for example for detecting excessive distortion or vibration of rotor blades in a turbine. ... Oxford University Innovation Limited

02/02/17 / #20170027496

Medical imaging

The present invention relates to methods for assessing or obtaining an indication of vascular pressure associated with organs or visceral tissues of the body by using mri imaging methods. The invention particularly relates to methods for assessing or obtaining an indication of portal hypertension using magnetic resonance t1, or t1 and t2* relaxometry, and t1, t2 and/or t2* mapping of the liver or spleen.. ... Oxford University Innovation Limited

01/19/17 / #20170018312

Quantum technology

A device for the storage and/or processing of quantum information comprises: a body (6), formed from a material having negligible net nuclear or electronic magnetic field; a set of data entities (4) embedded in said body, each having a plurality of magnetic field states; a set of probes (2), offset from the body, arranged to acquire internal phase shifts due to the magnetic fields of said data entities; wherein the probes (2) are each arranged to move relative to a plurality of data entities (4) in order that each probe (2) acquires an internal phase shift from the plurality of data entities (4); and means for reading each probe (2), thereby establishing a parity of the plurality of data entities (4).. . ... Oxford University Innovation Limited

01/19/17 / #20170016913

Methods and system for determining the disease status of a subject

A method of determining the osteoarthritis, inflammatory arthritis or joint injury status in a subject, and a panel of test biomarkers for use in determining same is disclosed. In particular, the method comprise the steps of determining the expression levels of at least three test biomarkers in a sample of bodily fluid obtained from the subject; conducting a statistical analysis of the correlation and relative expression levels between the at least three biomarkers; calculating a statistical score based on the statistical analysis; and comparing the statistical score with reference statistical scores generated from at least three reference group expression profiles to predict, diagnose, monitor or determine one or more of osteoarthritis, inflammatory arthritis or joint injury. ... Oxford University Innovation Limited

01/12/17 / #20170009582

Rotary engine seals

The invention relates to a rotor assembly having a sealing system for sealing at apexes or faces of the rotor. In a disclosed arrangement the apex seal or the face seal comprises a compliant member that is configured such that the shape or orientation of the compliant member can change in use in response to a change in the speed of rotation of the rotor, a change in the pressurisation across the compliant member, or a change in clearance between the sealing surface and a mounting element to which the compliant member is mounted, to deflect towards or away from the sealing surface.. ... Oxford University Innovation Limited

01/12/17 / #20170008849

Quinoline compounds

The present invention relates to quinoline compounds as defined by formula i below. Such quinoline compounds have been shown to inhibit the formation of amyloid deposits (e.g., amyloid oligomers, fibrils or plaques). ... Oxford University Innovation Limited

01/12/17 / #20170007433

Stent placement device

A stent placement assembly is disclosed. In disclosed example, the stent placement assembly comprises a stent placement assembly, comprising: a holding catheter comprising a longitudinal lumen for receiving a stent, and an output orifice at a distal end; a stopper member positioned within said lumen and moveable longitudinally relative thereto, the stopper member being configured to engage with the stent in order to restrict movement of the stent in a proximal direction; a first anchor member coupled to the holding catheter at a proximal end thereof; a second anchor member coupled to the stopper member at a proximal end thereof; and a displacement device comprising a first engagement member and a second engagement member, the first and second engagement members being configured to engage respectively with the first and second anchor members in such a way that displacement of the first engagement member relative to the second engagement member causes a corresponding displacement between the first and second anchor members, wherein: the displacement device further comprises: a handle rigidly connected to one of the first and second engagement members and a user actuatable displacement mechanism configured to be actuatable by a user while gripping the handle, the actuation being such as to cause displacement of the other one of the first and second engagement members relative to the handle thereby causing the holding catheter to withdraw in a proximal direction relative to the stopper member and thereby release the stent through the output orifice.. ... Oxford University Innovation Limited








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