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Principia Biopharma Inc patents


Recent patent applications related to Principia Biopharma Inc. Principia Biopharma Inc is listed as an Agent/Assignee. Note: Principia Biopharma Inc may have other listings under different names/spellings. We're not affiliated with Principia Biopharma Inc, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "P" | Principia Biopharma Inc-related inventors


 new patent  Compositions for ileo-jejunal drug delivery

The current invention affords new formulations which deliver reversible and irreversible covalent kinase inhibitors, in particular btk inhibitors, into the small intestine and specifically into the ileum and jejunum of the small intestine.. . ... Principia Biopharma Inc

Quinolone derivatives as fgfr inhibitors

Compounds that are fibroblast growth factor inhibitors (fgfr) and are therefore useful for the treatment of diseases treatable by inhibition of fgfr are disclosed. Also disclosed are pharmaceutical compositions containing such compounds and processes for preparing such compounds.. ... Principia Biopharma Inc

Quinolone derivatives as fibroblast growth factor receptor inhibitors

Compounds that are fibroblast growth factor inhibitors (fgfr) and are therefore useful for the treatment of diseases treatable by inhibition of fgfr are disclosed. Also disclosed are pharmaceutical compositions containing such compounds and processes for preparing such compounds.. ... Principia Biopharma Inc

Treatment of pemphigus

The present disclosure provides methods of treating with a btk inhibitor a blistering disease, in particular pemphigus vulgaris or pemphigus folliaceous in a mammal, use of a btk inhibitor as a replacement therapy for corticosteroid therapy for diseases treatable with a corticosteroid, such as autoimmune or inflammatory disease and in particular where corticosteroids are used as first or second line therapy, and pharmaceutical formulations comprising the same.. . ... Principia Biopharma Inc

Site specific dosing of a btk inhibitor

Disclosed herein are formulations and methods of site specific administration of compound (i) or a pharmaceutically acceptable salt thereof. Compound (i) is a potent btk inhibitor and hence can be useful for the treatment of diseases such as cancer, autoimmune, and inflammatory diseases.. ... Principia Biopharma Inc

Tyrosine kinase inhibitors

The present disclosure provides compounds that are tyrosine kinase inhibitors, in particular bruton tyrosine kinase (“btk”) inhibitors, and are therefore useful for the treatment of diseases treatable by inhibition of btk such as cancer, autoimmune, inflammatory, and thromboembolic diseases. Also provided are pharmaceutical compositions containing such compounds and processes for preparing such compounds.. ... Principia Biopharma Inc

Salts and solid form of a btk inhibitor

Disclosed herein are processes for preparing 2-[(3r)-3-[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile free base (compound (i)), salts of compound (i) and solid state form of said salts. Also disclosed herein are pharmaceutical compositions comprising such salts and solid state form thereof and methods of treating cancer, autoimmune, and inflammatory diseases using compound (i) or a pharmaceutically acceptable salt thereof.. ... Principia Biopharma Inc








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