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Promega Corporation patents


Recent patent applications related to Promega Corporation. Promega Corporation is listed as an Agent/Assignee. Note: Promega Corporation may have other listings under different names/spellings. We're not affiliated with Promega Corporation, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "P" | Promega Corporation-related inventors


 new patent  Activation of bioluminescence by structural complementation

Provided herein are compositions and methods for the assembly of a bioluminescent complex from two or more non-luminescent (e.g., substantially non-luminescent) peptide and/or polypeptide units. In particular, bioluminescent activity is conferred upon a non-luminescent polypeptide via structural complementation with another, complementary non-luminescent peptide.. ... Promega Corporation

Cleavable surfactants

The invention provides surfactant compounds of formulas i-ix, which can be used in methods for aiding the solubilization, digestion, preparation, analysis, and/or characterization of biological material, for example, proteins or cell membranes. The compounds can also aid in the recovery of peptides generated during protein digestion, particularly for in-gel digestion protocol. ... Promega Corporation

5,5-disubstituted luciferins and their use in luciferase-based assays

Described are luciferin analogues, methods for making the analogues, kits including the analogues, and methods of using the compounds for the detection of luminescence in luciferase-based assays.. . ... Promega Corporation

Cell impermeable coelenterazine analogues

Described are coelenterazine analogues, methods for making the analogues, kits comprising the analogues, and methods of using the compounds for the detection of luminescence in luciferase-based assays.. . ... Promega Corporation

Led-based illumination apparatus for configuration with a spectro-fluorometer system

An illumination apparatus for configuration with spectro-fluorometer system includes at least one light emitting diode (led), a collimator, and a light guide. The at least one led may be configured to emit light including a first beam-width angle. ... Promega Corporation

Coelenterazine analogues tethered to energy acceptors

Described are coelenterazine analogues, methods for making the analogues, kits comprising the analogues, and methods of using the compounds for the detection of luminescence in luciferase-based assays.. . ... Promega Corporation

Activation of bioluminescence by structural complementation

Provided herein are compositions and methods for the assembly of a bioluminescent complex from two or more non-luminescent (e.g., substantially non-luminescent) peptide and/or polypeptide units. In particular, bioluminescent activity is conferred upon a non-luminescent polypeptide via structural complementation with another, complementary non-luminescent peptide.. ... Promega Corporation

Radio frequency identification tray systems and methods

A radio frequency identification (rfid) tray for use with a cloud application platform is described. A cloud application, operatively coupled to the rfid tray via the cloud application platform, issues a command to the rfid tray. ... Promega Corporation

Dual protected pro-coelenterazine substrates

Described are coelenterazine analogues, methods for making the analogues, kits comprising the analogues, and methods of using the compounds for the detection of luminescence in luciferase-based assays.. . ... Promega Corporation

Synthetic oplophorus luciferases with enhanced light output

A polynucleotide encoding a modified luciferase polypeptide. The modified luciferase polypeptide has at least 60% amino acid sequence identity to a wild-type oplophorus luciferase and includes at least one amino acid substitution at a position corresponding to an amino acid in a wild-type oplophorus luciferase of seq id no:1. ... Promega Corporation

Oxidized glutathione assay

The present invention provides an assay for detection of oxidized glutathione (gssg).. . ... Promega Corporation

Coelenterazine analogues

Described are coelenterazine analogues, methods for making the analogues, kits comprising the analogues, and methods of using the compounds for the detection of luminescence in luciferase-based assays.. . ... Promega Corporation

Palladium catalysts with improved performance in biological environments

Provided herein are palladium (pd) catalysts with improved performance in biological environments. In particular, formulations, methods of preparations, and storage conditions are provided that provide improved performance of pd catalysts under protein-rich conditions.. ... Promega Corporation

Mobile rfid container and distribution method

A transportable container is enabled with radio frequency identification (“rfid”) technologies to maintain automated inventory levels of those items that are inside the container. The inventory data is communicated via wireless methods, such as cellular or wi-fi, to a remote device such as enterprise resource planning (“erp”) system. ... Promega Corporation

10/05/17 / #20170283456

Protein labeling with cyanobenzothiazole conjugates

The invention provides compounds and methods for site-specifically labeling proteins with cyanobenzothiazole derivatives of formula i. For example, the invention provides methods for labeling the n-terminus of a protein that terminates with a cysteine residue. ... Promega Corporation

08/17/17 / #20170233789

Coelenterazine analogues

Described are coelenterazine analogues, methods for making the analogues, kits comprising the analogues, and methods of using the compounds for the detection of luminescence in luciferase-based assays.. . ... Promega Corporation

07/06/17 / #20170191985

Luminescence-based methods and probes for measuring cytochrome p450 activity

The invention provides compounds, compositions, methods, substrates, and kits useful for analyzing the metabolic activity in cells, tissue, and animals and for screening test compounds for their effect on cytochrome p450 activity. In particular, a one-step and two-step methods using luminogenic molecules, e.g. ... Promega Corporation

05/18/17 / #20170140335

Radio frequency identification system

A multi-tenant, rfid system that may be cloud based or run on a local area network (lan) for distributed rfid devices and rfid applications. The rfid system a central abstraction and translation layer between rfid devices installed in geographically diverse locations and applications. ... Promega Corporation

05/18/17 / #20170137793

Polynucleotides encoding mutant hydrolase proteins with enhanced kinetics and functional expression

The invention provides a mutant hydrolase protein with enhanced kinetics and functional expression, as well as polynucleotides encoding the mutant proteins and methods of using the polynucleotides and mutant proteins.. . ... Promega Corporation

05/18/17 / #20170137456

Reversible metal ion chelators

Provided herein are chelator constructs (e.g., nucleic acid, peptide, peptide nucleic acid, etc.) that sequester metal ions (e.g., mg2+) under a first set of conditions and fail to sequester or release sequestered metal ions under a second set of conditions. In particular, nucleic acid constructs are provided that sequester metal ions (e.g., mg2+) under conditions that favor secondary and tertiary structure formation and release or fail to sequester metal ions under conditions that disfavor the formation of such structures.. ... Promega Corporation

04/27/17 / #20170115283

Compositions and methods for capture of cellular targets of bioactive agents

The present invention provides compositions and methods for capture and identification of the cellular targets of a bioactive agent. In particular, provided herein are bioactive agents tethered to capture ligand, cellular targets (optionally tagged with a reporter), capture proteins (optionally present as capture fusions), surfaces (e.g., displaying, capture ligands, capture proteins, or capture fusions), and methods of capturing and identifying the cellular targets of a bioactive agent therewith.. ... Promega Corporation

04/06/17 / #20170097356

Covalent tethering of functional groups to proteins and substrates therefor

A mutant hydrolase optionally fused to a protein of interest is provided. The mutant hydrolase is capable of forming a bond with a substrate for the corresponding nonmutant (wild-type) hydrolase which is more stable than the bond formed between the wild-type hydrolase and the substrate and has at least two amino acid substitutions relative to the wild-type hydrolase. ... Promega Corporation

04/06/17 / #20170096560

Methods for synthesizing rhodamine dyes

Described herein are methods for the regioselective synthesis of substituted rhodamine dyes.. . ... Promega Corporation

03/30/17 / #20170088877

Covalent tethering of functional groups to proteins

A mutant hydrolase optionally fused to a protein of interest is provided. The mutant hydrolase is capable of forming a bond with a substrate for the corresponding nonmutant (wild-type) hydrolase which is more stable than the bond formed between the wild-type hydrolase and the substrate. ... Promega Corporation

01/19/17 / #20170016888

Protein labeling with cyanobenzothiazole conjugates

The invention provides compounds and methods for site-specifically labeling proteins with cyanobenzothiazole derivatives of formula i. For example, the invention provides methods for labeling the n-terminus of a protein that terminates with a cysteine residue. ... Promega Corporation

01/05/17 / #20170002396

Red-shifted luciferins and methods of using same

Novel red-shifted luciferin derivatives and uses of those compounds are provided.. . ... Promega Corporation








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