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Quark Pharmaceuticals Inc patents


Recent patent applications related to Quark Pharmaceuticals Inc. Quark Pharmaceuticals Inc is listed as an Agent/Assignee. Note: Quark Pharmaceuticals Inc may have other listings under different names/spellings. We're not affiliated with Quark Pharmaceuticals Inc, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "Q" | Quark Pharmaceuticals Inc-related inventors


Sirna compounds comprising terminal substitutions

The invention relates to modified sirna compounds which down-regulate target gene expression, to pharmaceutical compositions comprising such compounds and to methods of treating and/or preventing the incidence or severity of various diseases or conditions associated with the genes and/or symptoms associated with such diseases or conditions.. . ... Quark Pharmaceuticals Inc

Double-stranded oligonucleotide molecules to ddit4 and methods of use thereof

Provided herein are double stranded nucleic acid molecules, compositions comprising same and methods of use thereof for the treatment of a subject wherein expression of ddit4 is associated with the etiology or progression of a disease or disorder in the subject. The compounds are preferably chemically synthesized and modified dsrna molecules.. ... Quark Pharmaceuticals Inc

Methods and compositions for preventing ischemia reperfusion injury in organs

The invention, in some embodiments, relates to compounds and methods for the prevention of ischemia reperfusion injury (iri) in organs, and in particular to iri in organs aged 35 years and older. Specific uses include prevention of iri in native organs in vivo, in reimplantations and in transplantations of donor organs aged 35 years and older. ... Quark Pharmaceuticals Inc

Methods for treating eye disorders

The present invention relates to compositions and methods for inhibiting loss of a retinal ganglion cell in a subject, comprising non-invasively applying to the surface of the eye of the subject an ophthalmic composition comprising a therapeutically effective amount of at least one sirna which down regulates expression of a target gene associated with loss of the retinal ganglion cell, thereby inhibiting loss of the retinal ganglion cell in the subject. The methods of the invention also relate to the use of chemically modified sirna compounds possessing structural motifs which down-regulate the expression of human genes expressed in retinal tissue in the mammalian eye.. ... Quark Pharmaceuticals Inc

Methods of treating ischemia-reperfusion injury with sirnas

The disclosure relates to compounds, in particular sirnas that inhibit the expression of specific human genes, for treating ocular diseases or disorders. The invention also relates to pharmaceutical compositions comprising such compounds and a pharmaceutically acceptable carrier. ... Quark Pharmaceuticals Inc

Methods and compositions for preventing ischemia reperfusion injury in organs

The invention, in some embodiments, relates to compounds and methods for the prevention of ischemia reperfusion injury (iri) in organs, and in particular to iri in organs aged 35 years and older. Specific uses include prevention of iri in native organs in vivo, in reimplantations and in transplantations of donor organs aged 35 years and older. ... Quark Pharmaceuticals Inc








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