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Roche Diagnostics Operations Inc patents (2016 archive)


Recent patent applications related to Roche Diagnostics Operations Inc. Roche Diagnostics Operations Inc is listed as an Agent/Assignee. Note: Roche Diagnostics Operations Inc may have other listings under different names/spellings. We're not affiliated with Roche Diagnostics Operations Inc, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "R" | Roche Diagnostics Operations Inc-related inventors


Device and method for handling racks of disposable pipette tips in a laboratory automation system and laboratory automation system

A device and method for handling racks of disposable pipette tips in a laboratory automation system are presented. The device comprises a guide rail for guiding racks from a loading region (i) to a supply region (ii). ... Roche Diagnostics Operations Inc

Armet as a marker for cancer

Disclosed is a method aiding in the assessment of cancer. More specifically disclosed is the use of the arginine-rich metastasized in early tumors protein (=armet) as a universal marker of different cancer types. ... Roche Diagnostics Operations Inc

In-vitro diagnostic analysis method and system

A method and system for automatic in-vitro diagnostic analysis are described. The method comprises adding a first reagent type and a second reagent type to a first test liquid during a first and second cycle times respectively. ... Roche Diagnostics Operations Inc

In-vitro diagnostic analysis method and system

A method and system for automatic in-vitro diagnostic analysis are described. The method comprises adding a first reagent type and a second reagent type to a first test liquid during a first and second cycle times respectively. ... Roche Diagnostics Operations Inc

Release reagent for vitamin d compounds

A reagent composition for releasing vitamin d compounds bound to vitamin d-binding protein, an in vitro method for the detection of a vitamin d compound in which the vitamin d compound is released from vitamin d-binding protein by the use of this reagent composition and the reagent mixture obtained in this manner. The use of the disclosed reagent composition to release vitamin d compounds as well as a kit for detecting a vitamin d compound which contains the reagent composition for releasing vitamin d compounds in addition to common detecting reagents.. ... Roche Diagnostics Operations Inc

Method and device for assigning a blood plasma sample

A device and method for assigning a blood plasma sample to a class from a predetermined set of classes are presented. The set of classes comprises a good class, a lipemic class, a hemolytic class and an icteric class. ... Roche Diagnostics Operations Inc

Method of operating a laboratory sample distribution system, laboratory sample distribution system and a laboratory automation system

A method of operating a laboratory sample distribution system is disclosed. The laboratory sample distribution system comprises a plurality of sample container carriers. ... Roche Diagnostics Operations Inc

Method of operating a laboratory automation system and a laboratory automation system

A method of operating a laboratory automation system is presented. The laboratory automation system comprises a plurality of laboratory stations and a plurality of sample container carriers. ... Roche Diagnostics Operations Inc

Biomarkers for risk assessment and treatment monitoring in heart failure patients guided by natriuretic peptides

The present invention relates to a method for identifying a patient who is eligible to an intensification of heart failure therapy. Furthermore, the present invention relates to a method for optimizing bnp-type peptide guided heart failure therapy. ... Roche Diagnostics Operations Inc

Prediction of postpartum hellp syndrome, postpartum eclampsia or postpartum preeclampsia

The present invention is directed to a method for predicting the risk of a female subject to develop postpartum hellp syndrome, postpartum preeclampsia, or postpartum eclampsia. The method is based on the determination of the levels of i) sflt-1 and plgf, or ii) endoglin and plgf in a first sample obtained from said subject before delivery of baby, and a second sample of from said subject obtained after delivery of baby. ... Roche Diagnostics Operations Inc

Means and methods for universal calibration of anti-factor xa tests

The present invention concerns diagnostic methods for coagulation testing involving determining anticoagulant activity elicited by a first anticoagulant in a sample comprising measuring a first factor xa activity in a body fluid test sample of said subject, measuring a second factor xa activity in at least one calibrator sample comprising a predefined anticoagulation activity for a second anticoagulant, calculating an universal parameter for the anticoagulation activity comprised in the test sample based on the first and the second measured factor xa activities and comparing the said parameter for the anticoagulation activity with predefined ranges of expected anticoagulation activity for at least three anticoagulants. Further provided is a computer program code assisting the method as well as a system for carrying out the said method as well as a kit.. ... Roche Diagnostics Operations Inc

Stabilization of whole blood at room temperature

The present disclosure is directed to the stabilization of nucleated cells in a whole blood sample ex-vivo, effected by an additive being a liquid composition for stabilizing an analyte in intact nucleated cells of a whole-blood sample ex-vivo, the composition being an aqueous solution, the solution comprising an anticoagulant, a phosphate salt, a cell-metabolizable sugar, adenine, and an antioxidant, wherein the antioxidant comprises a mitochondria-targeted antioxidant, preferably a mitochondria-targeted antioxidant selected from the group consisting of skq1, mitoq, ss-31, and a mixture thereof. In a specific embodiment, the liquid composition further comprises a protease inhibitor. ... Roche Diagnostics Operations Inc

Point-of-care testing system

A point of care (poc) testing system and a method for configuration of a poc testing system are disclosed that provide a workflow solution for the configuration management of poc analyzers. In some embodiments, the system and method provide for convenient assisted workflows that enable efficient management of poc analyzer operator certifications.. ... Roche Diagnostics Operations Inc

Point-of-care testing system

A point of care (poc) testing system and a method for configuration of a poc testing system are disclosed that provide a workflow solution for the configuration management of poc analyzers. The poc system and method provide for convenient assisted workflows that enable efficient replacement of poc analyzers and enable traceable relocation of poc analyzers within, for example, a hospital.. ... Roche Diagnostics Operations Inc

11/03/16 / #20160320274

Microfluidic element for thoroughly mixing a liquid with a reagent

A microfluidic element for thoroughly mixing a liquid with a reagent used for the analysis of the liquid for an analyte contained therein and a method thereof are disclosed. The microfluidic element has a substrate and a channel structure. ... Roche Diagnostics Operations Inc

11/03/16 / #20160319268

Blends containing proteases

Described are compositions, in particular lyophilizates, containing proteolytic enzymes, and methods for producing the compositions. Typically these compositions contain one or more proteases with collagenase activity and a neutral protease, for example, thermolysin. ... Roche Diagnostics Operations Inc

10/20/16 / #20160303556

Pressure transmission liquid for cellular analyzer, cellular analyzer and method for analyzing a liquid cellular sample

A pressure transmission liquid for a cellular analyzer, a cellular analyzer, and a method for analyzing a liquid cellular sample using such a cellular analyzer are disclosed. The pressure transmission liquid comprises an aqueous solution of at least one substance, wherein the solution has isotonic and substantially non-conductive characteristics. ... Roche Diagnostics Operations Inc

10/13/16 / #20160299163

System for processing closed sample tubes

A system for processing sample tubes comprising biological samples is presented. The system comprises two or more work cells for processing samples. ... Roche Diagnostics Operations Inc

10/13/16 / #20160299162

System for processing closed sample tubes

A system for processing sample tubes comprising biological samples is presented. The system comprises two or more work cells for processing samples. ... Roche Diagnostics Operations Inc

09/29/16 / #20160282378

Laboratory sample distribution system and laboratory automation system

A laboratory sample distribution system comprising a transport plane and a cleaning device for cleaning the transport plane is presented. The cleaning device is adapted to automatically clean the transport plane similar to sample container carriers moving also on the transport plane. ... Roche Diagnostics Operations Inc

09/22/16 / #20160276080

Process for producing magnetic monodisperse polymer particles

Disclosed is a simplified process for producing magnetic polymer particles. The process comprises: (a) providing a composition having a liquid monomer which is radical polymerizable, a radical initiator soluble in the monomer, a steric stabilizer, and a ferrofluid comprising surfactant-coated colloidal magnetic particles in a carrier fluid which is miscible with the monomer; (b) preparing an emulsion from a polar solvent which is immiscible with the monomer, and the composition of step (a); (c) adding seed polymer particles to the emulsion, mixing to form a seeded emulsion, and incubating the seeded emulsion, thereby swelling the seed polymer particles; and (d) activating the radical initiator and polymerizing the monomer in the swollen seed polymer particles; thereby producing the magnetic polymer particles. ... Roche Diagnostics Operations Inc

09/22/16 / #20160274137

Transport carrier, laboratory cargo distribution system, and laboratory automation system

A transport carrier for a laboratory cargo distribution system with a transport plane is disclosed. The transport carrier can be rotationally moved in an easily controllable manner on the transport plane. ... Roche Diagnostics Operations Inc

09/15/16 / #20160264925

Reagents for lysis of bacterial cells

The invention provides a composition containing an aqueous liquid phase, bacterial cells, and an ionic compound dissolved in the liquid phase. The ionic compound is selected from the group consisting of 1-butyl-3-methyl-imidazolium-thiocyanate, 1-butyl-3-methyl-imidazolium-2(2-methoxy-ethoxy)ethylsulfate, 1-methyl-1-[4-(3-methyl-3h-imidazol-1-ium)-but-1-yl]-3h-imidazolium-di(toluylsulfate), and 1-butyl-3-methyl-imidazolium-octylsulfate. ... Roche Diagnostics Operations Inc

09/01/16 / #20160254952

Pump configuration software wizard for configuring parameters of a handheld insulin pump

A system for configuring an insulin pump comprising: a computing device configured to receive a source device and a destination device; the source device being configured to communicate with the computing device, wherein the source device includes a source configuration file comprising a plurality of configurable source parameters; the destination device being configured to communicate with the computing device, wherein the destination device includes a destination configuration file comprising a plurality of configurable destination parameters; and the computing device being configured to determine whether a parameter mismatch occurred based on a comparison between the source configuration file and the destination configuration file; and to copies values associated with each of the plurality of source parameters to each of the plurality of destination parameters based on i) the determination of whether a parameter mismatch occurred and ii) the comparison between the source configuration file and the destination configuration file.. . ... Roche Diagnostics Operations Inc

09/01/16 / #20160252540

Cartridge for stirring and dispensing a fluid, automatic analyzer and method of analyzing a biological sample

A cartridge for dispensing a fluid is provided, the cartridge comprising: a reservoir chamber configured for receiving the fluid, the reservoir chamber having a fluid outlet and a cover with a first bearing; and a stirring assembly comprising a stirrer located inside the reservoir chamber, the stirring assembly comprising a shaft connected to the stirrer. The stirring assembly can be moved between first and second positions, wherein in the first position the stirring assembly can seal the fluid outlet, the stirring assembly in the first position being configured to form a second bearing with the reservoir chamber or the fluid outlet such that the stirrer can be rotated about an axis defined by the first and second bearing, and wherein if the stirring assembly is in the second position the fluid can pass through the fluid outlet, the shaft being configured to transmit rotational power to the stirrer.. ... Roche Diagnostics Operations Inc

09/01/16 / #20160252500

Method for determining the total amount and/or concentration of an analyte in the presence of a binding molecule as well as kits, compositions and uses relating thereto

The present invention relates to a method for determining the total amount and/or concentration of an analyte in the presence of a binding molecule as well as kits, compositions and uses relating thereto.. . ... Roche Diagnostics Operations Inc

09/01/16 / #20160252498

Use of a reagent for the lysis of erythrocytes as well as methods and kits relating thereto

The present disclosure relates to use of a reagent for the lysis of erythrocytes, a method of lysing erythrocytes and a kit comprising the reagent.. . ... Roche Diagnostics Operations Inc

08/25/16 / #20160245829

Release reagent for vitamin d compounds

A reagent composition for releasing vitamin d compounds bound to vitamin d-binding protein and an in vitro method for the detection of a vitamin d compound in which the vitamin d compound is released from vitamin d-binding protein by the use of this reagent composition as well as the reagent mixture obtained in this manner. Also disclosed is the use of the reagent compositions to release vitamin d compounds as well as a kit for detecting a vitamin d compound.. ... Roche Diagnostics Operations Inc

08/25/16 / #20160245827

L-fabp based diagnosis of kidney injury after an acute event or after a surgical intervention

Systems and methods for diagnosing acute kidney injury following an acute event or surgical intervention, based on assessing the biomarker l-fabp. Also, systems and methods for predicting the risk of an individual to suffer from a kidney injury after an acute event or surgical intervention in the future.. ... Roche Diagnostics Operations Inc

08/18/16 / #20160238588

Communication interface clip for a handheld medical device

A communication interface apparatus is provided for use with a handheld medical test device. The communication interface apparatus is comprised of an attachment member configured to detachably couple to a housing of the medical test device, where the attachment member substantially overlays a rear side of the medical test device. ... Roche Diagnostics Operations Inc

08/18/16 / #20160237144

Thermus thermophilus slyd fkbp domain specific antibodies

The present description relates to anti-thermus thermophilus slyd fkbp domain antibodies and methods of using the same.. . ... Roche Diagnostics Operations Inc

08/11/16 / #20160232363

Controlling an analysis system of biological samples

A method for controlling an analysis system is presented. The method comprises receiving, by an encryption unit, authentication data of a user. ... Roche Diagnostics Operations Inc

08/11/16 / #20160231344

Cartridge for dispensing a fluid

A cartridge for dispensing fluid is presented. The cartridge comprises a valve. ... Roche Diagnostics Operations Inc

08/11/16 / #20160229565

Method and device for handling test tubes in a laboratory automation system

A method and a device for handling test tubes in a laboratory automation system are presented. During the handling, an open end of the test tube is covered by a residue-free removable, flat cover element forced against the open end of the test tube.. ... Roche Diagnostics Operations Inc

08/11/16 / #20160229051

Robotic device and laboratory automation system comprising robotic device

A robotic device is presented. The robotic device comprises a stationary base, a first arm rotationally mounted on the base for rotation about a first axis (i), a second arm rotationally mounted on the first arm for rotation about a second axis (ii), in which second axis (ii) is parallel to the first axis (i), a first driving device for driving the first arm to rotate about the first axis (i), and a second arm drive unit with a second driving device for driving the second arm to rotate about the second axis (i). ... Roche Diagnostics Operations Inc

07/28/16 / #20160216289

Method to perform a measurement of an analyte in a sample using an automatic analyzer

A method of performing a measurement of an analyte in a sample using an automatic analyzer is provided. The automatic analyzer comprises: a cartridge for dispensing a fluid, a measurement unit for performing the measurement, a sample holder for receiving the sample, and a pump for pumping the fluid out of the cartridge and into the sample holder. ... Roche Diagnostics Operations Inc

07/21/16 / #20160209329

Method for recognizing a state of a sample, device for analyzing samples and laboratory automation system

A method for automated identification of a state of a sample such as, for example, for identifying whether or not the sample was centrifuged is presented. A device for analyzing samples and a laboratory automation system are also presented in which the method is applied.. ... Roche Diagnostics Operations Inc

07/07/16 / #20160194410

Binding agent

A binding agent of the formula a-a′:a-s-b:b′-b:x(n), wherein a as well as b is a monovalent binder, a′:a as well as b:b′ is a binding pair wherein a′ and a do not interfere with the binding of b to b′ and vice versa, s is a spacer of at least 1 nm in length, :x denotes a functional moiety bound either covalently or via a binding pair to at least one of a′, a, b, b′ or s, (n) is an integer and at least 1, — represents a covalent bond, and the linker a-s-b has a length of 6 to 100 nm. Also disclosed are methods of producing such binding agent and certain uses thereof.. ... Roche Diagnostics Operations Inc

06/16/16 / #20160169926

Device for storing of fluid containers

A device for container storing is presented. The device comprises storage with at least one storing level including a pipetting storing level for fluid pipetting. ... Roche Diagnostics Operations Inc

06/16/16 / #20160169911

Marker for statin treatment stratification in heart failure

The present invention is directed to a method of identifying a patient having heart failure as likely to respond to a therapy comprising a statin. The method is based on measuring the level of at least one marker selected from gdf-15 (growth differentiation factor 15), urea, shbg (sex hormone-binding globulin), uric acid, plgf (placental growth factor), il-6 (interleukin-6), transferrin, a cardiac troponin, sflt-1 (soluble fms-like tyrosine kinase-1), prealbumin, ferritin, osteopontin, sst2 (soluble st2), and hscrp (high sensitivity c-reactive protein) in a sample from a patient. ... Roche Diagnostics Operations Inc

06/16/16 / #20160169895

Flap endonuclease-1 as a marker for cancer

Methods aiding in the assessment of cancer comprising use of the flap endonuclease-1 protein (=fen1) as a universal marker of different cancer types are provided. In particular, methods for assessing cancer from a liquid sample derived from an individual, which comprise measuring fen1 in the sample are disclosed. ... Roche Diagnostics Operations Inc

06/09/16 / #20160161521

Automatic analyzer

An automatic analyzer provided with a roller and a reagent container shoulder presser at the position where an operator inserts a reagent container into the automatic analyzer. The reagent container is pushed while the lid of the reagent container is made to touch the upper side of the roller and the shoulder presser is made to touch the shoulder of the reagent container, and the application of upward force to the lid causes the lid of the reagent container to be half open, after which the reagent container is inserted in the analyzer.. ... Roche Diagnostics Operations Inc

06/09/16 / #20160161480

Method for the detection of the prozone effect of photometric assays

A method for determination of the amount of a specific analyte in a sample which may show a prozone effect by photometric assays, wherein the specific analyte is quantified from the change in the optical signal of the reaction mixture after the interaction of the analyte with analyte specific assay reagents. The optical signal is measured simultaneously for the specific analyte in the sample to be determined at the wavelength used for the determination of the analyte and at least at an additional specific wavelength used for the detection of the prozone effect over the complete reaction time. ... Roche Diagnostics Operations Inc

06/09/16 / #20160159579

Device for repositioning tubes in a tube rack

A device for repositioning tubes in a tube rack is presented. The device comprises a base; a mount movable relative to the base in a first and second direction; an actuator for moving the mount; grippers coupled to and movable with the mount, each gripper comprising arms with portions for gripping a tube; a biasing element coupled to the mount and to the arms to be movable relative to the mount and to move the portions towards/away from each other; a blocking element coupled to the base to engage the biasing element and to block movement of the biasing element with respect to the mount against a force where the mount is moved in the first direction to move the portions towards each other and to disengage from the biasing element when the mount is moved in the second direction to allow the portions to be moved apart.. ... Roche Diagnostics Operations Inc

06/02/16 / #20160154621

Analysis system for analyzing biological samples, data processing method and computer program product

Embodiments related to analysis system for analyzing biological samples, a data processing method and a computer program product are disclosed. An analyzer is coupled to an control computer and has a control application program which receives control data, sends analytical data, and generates a host screen image. ... Roche Diagnostics Operations Inc

05/26/16 / #20160145281

New iridium-based complexes for ecl

Novel iridium-based ir(iii) luminescent complexes, conjugates comprising these complexes as a label and their application, for example in the electrochemiluminescence based detection of an analyte.. . ... Roche Diagnostics Operations Inc

05/19/16 / #20160139075

Method and system for hydrating and calibrating an electrochemical sensor

Methods and systems for hydrating and calibrating an electrochemical sensor are disclosed. The method comprises providing an electrochemical sensor, providing a calibration solution to a measuring chamber of the electrochemical sensor, contacting the sensor with the calibration solution within the measuring chamber, exposing the sensor and the calibration solution to an elevated temperature, and over a cooling period, cooling the sensor and the calibration solution with a tempering device, wherein the temperature is controllable within a device error range of temperature, performing a plurality of calibrations of the sensor, wherein a calibration of the plurality of calibrations is valid for a calibration margin of temperature error, the calibration margin of temperature error exceeds the device error range of temperature, and controlling a decrease of the temperature of the sensor and the calibration solution not to exceed the calibration margin of temperature error between consecutive calibrations of the sensor.. ... Roche Diagnostics Operations Inc

05/19/16 / #20160137728

Antibody specifically binding to insulin-like growth factor-1

Isolated antibodies that specifically bind to an epitope comprised in the stretch of amino acids ranging from amino acid 76 to amino acid 84 of human insulin-like growth factor-1 precursor (seq id no:1). Use of the novel antibodies for the sensitive and specific detection of insulin-like growth factor-1, in some embodiments while in the presence of high excess concentration of insulin-like growth factor-2, for example in a bodily fluid sample.. ... Roche Diagnostics Operations Inc

05/05/16 / #20160124006

Method for handling a sample tube and handling device

A method and a device for handling sample tubes are presented. A position of the sample tube is identified and the sample tube is handled depending thereon.. ... Roche Diagnostics Operations Inc

04/07/16 / #20160097786

Module for a laboratory sample distribution system, laboratory sample distribution system and laboratory automation system

A module for a laboratory sample distribution system, a laboratory sample distribution system comprising such modules, and a laboratory automation system comprising such a laboratory sample distribution system are presented. A magnetic coupling enhancer is provided in order to increase magnetic coupling between adjacent modules.. ... Roche Diagnostics Operations Inc

04/07/16 / #20160097785

Calibration method for photometry

A method for determining a physical property of a biological sample. The method comprises the steps of: acquiring a set of preliminary calibration signals of a first lot of a reagent using an automatic analyzer with a first photometry module; acquiring a reference set of signals of the first lot of the reagent using a calibration analyzer with a second photometry module; determining a set of module specific components by subtracting the reference set of signals from the preliminary calibration signals; acquiring a lot specific set of signals of a second lot of the reagent using the second photometry module; determining a lot calibration for the first photometry module using the set of module specific components and the lot specific set of signals; acquiring a measurement signal of the biological sample using the first photometry module and the second lot of the reagent; and determining a physical property of the biological sample using the measurement signal and the lot calibration.. ... Roche Diagnostics Operations Inc

04/07/16 / #20160097765

Electrochemiluminescence method of detecting an analyte in a liquid sample and analysis system

An electrochemiluminescence method of detecting an analyte in a liquid sample and a corresponding analysis system. An analyte in a liquid sample is detected by first providing a receptacle containing a fluid comprising protein coated magnetic microparticles to a stirring unit. ... Roche Diagnostics Operations Inc

03/31/16 / #20160091482

Method and system for detecting an analyte in a body fluid

A method for detecting at least one analyte in a body fluid is disclosed comprising performing an optical measurement, wherein at least one test chemical is contacts the body fluid. The test chemical is an optical test chemical adapted to perform at least one detection reaction, wherein at least one optically detectable property is changed due to the detection reaction to provide at least one optical measurement value. ... Roche Diagnostics Operations Inc

03/31/16 / #20160090398

Novel compounds useful for fret and methods related thereto

The invention also relates to compounds, which are useful for intra-molecular fluorescence resonance energy transfer (fret), comprising the oxidized form of a carbanadh-based first fluorophore and a second fluorophore that is excitable at a wave-length of between 445 to 540 nm and that has an emission maximum of greater than 560 nm, and methods, kits and compositions related thereto.. . ... Roche Diagnostics Operations Inc

03/31/16 / #20160089867

Method and device for producing a test element

A method and a production device for producing a test element are disclosed. The method comprises providing in a transport step a continuous substrate tape, wherein the tape is transported in a transport direction parallel to a direction of extension of the continuous substrate tape; applying in an adhesive application step at least one continuous adhesive strip, wherein the strip is applied to the continuous substrate tape with a liquid adhesive and a slot coating process, and wherein the continuous adhesive strip is oriented parallel to the transport direction; applying in a cover element application step at least one cover element, wherein the at least one cover element is applied to the continuous adhesive strip, thereby securing the cover element to the continuous substrate tape; and individualizing in an individualization step the continuous substrate tape, wherein the tape is individualized into single test elements.. ... Roche Diagnostics Operations Inc

03/24/16 / #20160084861

Calibration for multi-component assays

A method of analyzing a biological sample using an analyzer and an assay. The method comprises providing the assay for producing the signal. ... Roche Diagnostics Operations Inc

03/17/16 / #20160077120

Laboratory sample distribution system and laboratory automation system

A laboratory sample distribution system having a recovery device and a laboratory automation system having such a laboratory sample distribution system are presented. The recovery device is adapted to manipulate items such as sample container carriers or sample containers on a transport plane of the laboratory sample distribution system in the case of an error condition.. ... Roche Diagnostics Operations Inc

03/17/16 / #20160076068

Quantitative control of sialylation

The present disclosure is directed to the use of certain glycosyltransferase variants having n-terminal truncation deletions. Contrary to previous findings certain truncations were found to exhibit sialidase enzymatic activity, particularly a variant of human sialyltransferase (hst6gal-i) with a truncation deletion involving the first 89 n-terminal amino acids of the respective wild-type polypeptide. ... Roche Diagnostics Operations Inc

03/17/16 / #20160075766

Method for producing antibodies using ovine b-cells and uses thereof

Herein is reported a cultivation system for cultivating a pool of ovine b-cells or single deposited ovine b-cells in the presence of phorbol myristate acetate (pma).. . ... Roche Diagnostics Operations Inc

03/10/16 / #20160069715

Laboratory sample distribution system and method for calibrating magnetic sensors

A laboratory sample distribution system comprising a calibration device, a calibration device and a method for calibrating magnetic sensors are disclosed. Magnetic sensors used in a laboratory sample distribution system are calibrated in order to optimize driving of sample container carriers and in order to detect long-term variation in detection characteristics of the magnetic sensors.. ... Roche Diagnostics Operations Inc

03/03/16 / #20160065590

Identification, authentication, and authorization method in a laboratory system

An identification, authentication and authorization method in a laboratory system is presented. The system comprises at least one laboratory device. ... Roche Diagnostics Operations Inc

03/03/16 / #20160061831

Automatic analysis device

An analyzing device of the present invention is provided with a flow chamber that a fluid including magnetic particles associated with a labeling substance flows from a fluid inlet to a fluid outlet, magnetic trap means to apply a magnetic field for trapping the magnetic particles to the fluid in the flow chamber, a working electrode and a counter electrode to apply a voltage to the magnetic particles trapped by the magnetic trap means, and to emit a luminescence, a light detection element to detect a luminescence derived from the labeling substance on the magnetic particles trapped in the flow chamber, and regulating means to regulate a region that the light detection element detects the luminescence derived from the labeling substance on a part of magnetic particles of them trapped by the magnetic trap means.. . ... Roche Diagnostics Operations Inc

02/25/16 / #20160054344

Laboratory sample distribution system, laboratory system and method of operating

A laboratory sample distribution system is presented. The laboratory sample distribution system comprises a plurality of container carriers. ... Roche Diagnostics Operations Inc

02/25/16 / #20160054341

Sample container carrier for a laboratory sample distribution system, laboratory sample distribution system and laboratory automation system

A sample container carrier, a laboratory sample distribution system comprising such a sample container carrier, and to a laboratory automation system comprising such a laboratory sample distribution system are presented. The sample container carrier can tilt a sample container in order to allow higher acceleration rates.. ... Roche Diagnostics Operations Inc

02/18/16 / #20160048691

Controlling an analysis system of biological samples

A method for controlling an analysis system is presented. The method comprises receiving, by an encryption unit, authentication data of a user. ... Roche Diagnostics Operations Inc

02/18/16 / #20160047771

Blood glucose meter with low cost user interface having programmed graphic indicators

A blood glucose meter with a low cost user interface has a color glucose scale that is indexed by indicators programmed according to the user's blood glucose target range through a separating computing device due to the limited meter user interface. The color glucose scale is static and placed adjacent to the indicator such as by being molded into the housing, printed on the housing, or attached to the display. ... Roche Diagnostics Operations Inc

02/04/16 / #20160032261

T7 rna polymerase variants with enhanced thermostability

The present invention provides improved variants of t7 rna polymerase by introducing novel mutations which lead to improved thermostability of the enzyme. According to the invention, amino acid substitutions at the positions val426, ser633, val650, thr654, ala702, val795, and combinations thereof are advantageous.. ... Roche Diagnostics Operations Inc

02/04/16 / #20160032260

T7 rna polymerase variants with enhanced thermostability

The present invention provides improved variants of t7 rna polymerase by introducing novel mutations which lead to improved thermostability of the enzyme. According to the invention, amino acid substitutions at the positions val426, ser633, val650, thr654, ala702, val795, and combinations thereof are advantageous.. ... Roche Diagnostics Operations Inc

01/28/16 / #20160025750

Release reagent for vitamin d compounds

A reagent composition for releasing vitamin d compounds bound to vitamin d-binding protein and an in vitro method for the detection of a vitamin d compound in which the vitamin d compound is released from vitamin d-binding protein by the use of this reagent composition as well as the reagent mixture obtained in this manner. Also disclosed is the use of the reagent compositions to release vitamin d compounds as well as a kit for detecting a vitamin d compound.. ... Roche Diagnostics Operations Inc

01/21/16 / #20160018411

Use of seprase for differential diagnosis of acute dyspnea

The present invention relates to a method for differentiating in a patient who suffers from acute shortness of breath (acute dyspnea) between pulmonary disease and cardiac disease. The method is based on measuring the levels of seprase and of a cardiac marker in a sample from said patient. ... Roche Diagnostics Operations Inc

01/14/16 / #20160011210

Troponin and bnp based diagnosis of risk patients and cause of stroke

Method for determination of whether a subject suffers from intermittent atrial fibrillation based on the determination of the amount of a troponin t in a sample in a patient suffering from atrial fibrillation using a binding assay. Kits and devices adapted to carry out the methods are also provided.. ... Roche Diagnostics Operations Inc

01/14/16 / #20160010069

T7 rna polymerase variants with cysteine-serine substitutions

The present disclosure provide novel variants of t7 rna polymerase. Embodiments of t7 variants, according to the instant invention, include a cysteine-serine substitution on position 723 of the amino acid sequence of the t7 polypeptide. ... Roche Diagnostics Operations Inc








ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009



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