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Roche Diagnostics Operations Inc patents (2018 archive)


Recent patent applications related to Roche Diagnostics Operations Inc. Roche Diagnostics Operations Inc is listed as an Agent/Assignee. Note: Roche Diagnostics Operations Inc may have other listings under different names/spellings. We're not affiliated with Roche Diagnostics Operations Inc, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "R" | Roche Diagnostics Operations Inc-related inventors


Device for detecting and logging a temperature of a fluid while placed in the fluid

A device for detecting and logging a temperature of a fluid while placed in the fluid is disclosed. The device comprises a microprocessor having an integrated temperature sensor. ... Roche Diagnostics Operations Inc

Secondary solid waste container for solid waste of an analyzer

A secondary solid waste container for solid waste of an analyzer is disclosed. The secondary solid waste container comprises side walls and an impact absorbing member. ... Roche Diagnostics Operations Inc

Determining a quantity of an analyte in a blood sample

A medical system for determining an analyte quantity in a blood sample via a cartridge that spins around a rotational axis. The cartridge may include: a separation chamber that separates blood plasma from the sample; a processing chamber containing a reagent with a specific binding partner which binds to the analyte to form an analyte specific binding partner complex; a first valve structure connecting the separation chamber to the processing chamber; a measurement structure to measure the quantity of the analyte, wherein the measurement structure includes a chromatographic membrane with an immobilized binding partner for direct or indirect binding of the analyte or the analyte specific binding partner complex, and an absorbent structure that is nearer to the axis than the membrane; a second valve structure connecting the processing chamber to the measurement structure; and a fluid chamber filled with a washing buffer and fluidically connected to the measurement structure.. ... Roche Diagnostics Operations Inc

Sample handling device and method for sample handling

A sample handling device is presented. The sample handling device comprises at least one magnetic positioning device for magnetically holding a carrier configured for carrying at least one vessel in the sample handling device. ... Roche Diagnostics Operations Inc

Increasing the usable dynamic range in photometry

An optical device for determining the presence and/or concentration of analytes in a sample is presented. The optical device comprises a detector and a detection unit comprising optical path components. ... Roche Diagnostics Operations Inc

In-vitro diagnostic analysis method and system

A method and system for automatic in-vitro diagnostic analysis are described. The method includes adding a first reagent type and a second reagent type to a first test liquid during a first and second cycle times respectively. ... Roche Diagnostics Operations Inc

Method and device for assigning a blood plasma sample

A device and method for assigning a blood plasma sample to a class from a predetermined set of classes are presented. The set of classes comprises a good class, a lipemic class, a hemolytic class and an icteric class. ... Roche Diagnostics Operations Inc

Igfbp7 for prediction of risk of aki when measured prior to surgery

The present disclosure describes a method for predicting the risk of a patient to suffer from acute kidney injury (aki) during or after a surgical procedure or after administration of a contrast medium. The method is based on the determination of the level of the biomarker igfbp7 (insulin-like growth factor binding protein 7) in a body fluid sample obtained from the patient prior to the surgical procedure or prior to the administration of a contrast medium. ... Roche Diagnostics Operations Inc

Methods of identifying an individual to be treated by chemotherapy based on marker molecules and related uses

The present disclosure relates to a method of identifying an individual having non-small cell lung carcinoma as to be treated by chemotherapy based on marker molecules cytokeratin-19 fragments (cyfra 21-1) and carcinoembryonic antigen (cea) as well as the use of the marker molecules for the identification of an individual to be treated by chemotherapy.. . ... Roche Diagnostics Operations Inc

Sensitivity and the dynamic range of photometric assays by generating multiple calibration

A method for determining the amount of a specific analyte by photometric assays, wherein the specific analyte in a sample reacts with an analyte specific reaction partner in a reaction mixture. At least two calibration curves are generated, the first calibration curve recorded at a first wavelength is optimized for low concentrations of the specific analyte thereby maximizing the lower detection limit and, the second calibration curve recorded at a second wavelength is optimized for high concentrations of the specific analyte thereby maximizing the upper detection limit. ... Roche Diagnostics Operations Inc

Reagent vessel for storing a liquid reagent, apparatus for manufacturing a lower part of a reagent vessel and a method for manufacturing a lower part of a reagent vessel

A reagent vessel, an apparatus and a method for manufacturing a lower part of a reagent vessel for an analytical instrument are disclosed. The reagent vessel is configured to store a liquid reagent. ... Roche Diagnostics Operations Inc

Laboratory automation system

A laboratory automation system for processing sample containers containing laboratory samples and/or for processing the samples is presented. The laboratory automation system comprises a digital camera configured to take an image of the sample container together with a calibration element. ... Roche Diagnostics Operations Inc

Rotatable cartridge for processing and analyzing a biological sample

An automatic analyzer cartridge, spinnable about a rotational axis, has fluid and aliquoting chambers, a metering chamber connected to a vent that is nearer to the rotational axis than the metering chamber, first and second ducts connecting the fluid and aliquoting chambers, and the metering and aliquoting chambers, respectively. Metering chamber side walls taper away from a central region, wherein capillary action next to the walls is greater than in the central region. ... Roche Diagnostics Operations Inc

Method of determining a handover position and laboratory automation system

A method for determining a handover position of a gripping device and to a laboratory automation system being able to perform such a method are presented. A position determining device is used in order to determine a handover position based on magnetic forces of a handover electro-magnetic actuator that is part of a laboratory sample distribution system of the laboratory automation system.. ... Roche Diagnostics Operations Inc

08/02/18 / #20180217174

Laboratory sample distribution system and laboratory automation system

A laboratory sample distribution system is presented. The system comprises carriers to carry sample containers. ... Roche Diagnostics Operations Inc

07/26/18 / #20180210001

Laboratory sample distribution system and laboratory automation system

A laboratory sample distribution system comprising a number of optically recognizable geometric shapes placed on a transport plane or a flat template for drawing such geometric shapes is presented. A laboratory automation system comprising such a laboratory sample distribution system is also presented.. ... Roche Diagnostics Operations Inc

07/26/18 / #20180210000

Laboratory

A laboratory with a laboratory sample distribution system being at least partially arranged in an underfloor chamber is presented.. . ... Roche Diagnostics Operations Inc

07/26/18 / #20180208359

Transport packaging for packaging hazardous materials

A method for packaging articles to be transported is provided comprising a) preparing at least one pallet comprising a base plate, which base plate forms an even plate-shaped element; b) placing the articles to be transported onto the base plate; c) providing a transport box that's open toward the base plate in an inverted orientation over the articles, wherein the transport box is placed on the base plate so that the transport box and base plate together form an interior of the transport packaging unit, wherein the transport box comprises an opening that's closable by folding flaps on a side opposite the base plate, wherein the transport box closes off flush with the pallet; and d) fixing the transport box on the base plate with at least one packing strip, wherein the transport box is pressed onto the base plate by said at least one packing strip.. . ... Roche Diagnostics Operations Inc

07/26/18 / #20180206768

Medical instrument with a shutter for sealing a test strip port

A medical instrument (300, 700, 1300, 1400, 1500, 1600) for performing a measurement (1513) on a biological sample using a test strip (310), wherein the medical instrument comprises: a housing (302) and an analytical unit (1508) for analyzing the test strip, wherein the analytical unit is within an interior volume (308). The analytical unit comprises a test strip mount (1510) configured for receiving the test strip to perform the measurement. ... Roche Diagnostics Operations Inc

07/12/18 / #20180196067

Identification of patients with abnormal fractional shortening

The present invention relates to a method for assessing whether a subject shall be subjected to an imaging based diagnostic assessment. The method is based on the determination of the amount(s) of a cardiac troponin and/or fibroblast growth factor 23 (fgf-23) in a sample from the subject, and on the comparison of the, thus, determined amount(s) with a reference amount (reference amounts). ... Roche Diagnostics Operations Inc

07/12/18 / #20180196066

Troponin and bnp based diagnosis of risk patients and cause of stroke

Method for determination of whether a subject suffers from intermittent atrial fibrillation based on the determination of the amount of a troponin t in a sample in a patient suffering from atrial fibrillation using a binding assay. Kits and devices adapted to carry out the methods are also provided.. ... Roche Diagnostics Operations Inc

07/05/18 / #20180188280

Laboratory sample distribution system and laboratory automation system

A laboratory sample distribution system is presented. The system comprises a number of sample container carriers, a transport plane, a number of electro-magnetic actuators, a number of position sensors and a position determination unit. ... Roche Diagnostics Operations Inc

06/21/18 / #20180172680

Particle-based immunoassay using a pegylated analyte-specific binding agent

Disclosed is a method for measurement of an analyte in a microparticle-based analyte-specific binding assay, wherein the microparticles are coated with the first partner of a binding pair, the method involving mixing the coated microparticles, an analyte-specific binding agent conjugated to the second partner of the binding pair, and a sample suspected of containing or containing the analyte, wherein the second partner of the binding pair is bound to the analyte-specific binding agent via a linker having from 12 to 30 ethylene glycol units (peg 12 to 30), thereby binding the analyte via the conjugated analyte-specific binding agent to the coated microparticles, separating the microparticles having the analyte bound via the binding pair and the analyte-specific binding agent from the mixture and measuring the analyte bound to the microparticles.. . ... Roche Diagnostics Operations Inc

06/21/18 / #20180172600

Characterizing the emission properties of samples

The present disclosure relates to a method for characterizing a light source. The method includes providing a light source to be characterized, collecting light emitted from the light source by using imaging optics, the imaging optics generating a pupil of the collected light emitted from the light source, generating an image of a pupil of light emitted only from a first surface area of the light source at a detector using the imaging optics, laterally shifting the light source and the imaging optics relative to each other and after the lateral shift, generating an image of a pupil of light emitted only from a second surface area of the light source at the detector using the imaging optics. ... Roche Diagnostics Operations Inc

06/14/18 / #20180164314

Alkaline pretreatment of parvoviruses for immunoassays

Disclosed is a method for detecting a capsid polypeptide of a non-enveloped virus in a sample from a subject which includes (a) contacting the sample with a base, and (b) detecting a capsid polypeptide of the virus in the sample. Moreover, the present disclosure relates to a method for pre-processing a sample from a subject for detection of a virus, including contacting the sample with a base. ... Roche Diagnostics Operations Inc

06/07/18 / #20180156835

Laboratory sample distribution system and laboratory automation system

A laboratory sample distribution system is presented. The system comprises a number of sample container carriers to carry one or more sample containers. ... Roche Diagnostics Operations Inc

06/07/18 / #20180156832

Tube rack transfer device and diagnostic instrument

A tube rack transfer device for transferring racks is presented. A first rail extends in a first horizontal direction and a second rail extends in a second horizontal direction orthogonal to the first direction. ... Roche Diagnostics Operations Inc

05/24/18 / #20180143944

Supplementing measurement results of automated analyzers

A computer-implemented method for supplementing measurement results of automated analyzers is presented. The method includes obtaining, at a computer device, a result of a measurement performed by an automated analyzer, the computer device and the automated analyzer being located within a privileged computer network, obtaining a context related algorithm associated with the result of the measurement defining one or more triggering conditions and context related information from a computer device residing outside of the privileged computer network at the computer device and processing the result of the measurement by using the context related algorithm to generate a context specific supplement to the result of the measurement at the computer device.. ... Roche Diagnostics Operations Inc

05/24/18 / #20180141935

Use of compounds comprising two or more hydrophobic domains and a hydrophilic domain comprising peg moieties for stabilization of a cell

The present invention relates to the use compounds comprising two or more hydrophobic domains and a hydrophilic domain comprising a polyethylene glycol (peg) moiety for stabilization of a cell, and methods related thereto.. . ... Roche Diagnostics Operations Inc

05/17/18 / #20180136243

Rotatable cartridge with multiple metering chambers

A method and cartridge for determining an amount of at least two analytes in a biological sample and an automatic analyzer are disclosed. The cartridge may comprise a cartridge inlet, a sample holding chamber fluidically connected to the inlet, and two or more metering chambers. ... Roche Diagnostics Operations Inc

05/10/18 / #20180128848

Sample container carrier, laboratory sample distribution system and laboratory automation system

A sample container carrier for a laboratory sample distribution system is presented. The sample container carrier comprises a magnetic element that is arranged such that a magnetic move force applied to the sample container carrier depends on an angularity. ... Roche Diagnostics Operations Inc

05/10/18 / #20180128846

Inventory alert system for laboratories

Disclosed herein is a system and computer implemented method for detecting extraordinary demand of a consumable(s) for processing biological samples by laboratory instrument(s) in a plurality of laboratories based on exceptional deviations from usual demand levels of trigger laboratories in the proximity of a target laboratory.. . ... Roche Diagnostics Operations Inc

05/10/18 / #20180128825

Methods for reducing interferences

The present invention relates to a method for determining an analyte in a sample suspected to comprise said analyte, comprising a) contacting with said sample at least a first and a second capture compound for said analyte, wherein said first and second capture compounds are non-identical capture compounds, and wherein said capture compounds compete in binding to said analyte; b) contacting said capture compounds contacted with said sample with a specifier, wherein said specifier competes in binding to said capture compounds with said analyte; c) determining the amount of complexes comprising said specifier and a capture compound; and d) determining said analyte in a sample based on the result of step c). The present invention further relates to a method for improving the specificity of an indirect immunoassay for determining an analyte, comprising replacing at least 10% of a capture compound by a non-identical capture compound; wherein the capture compound replaced competes in binding to said analyte with the capture compound introduced. ... Roche Diagnostics Operations Inc

05/03/18 / #20180120289

Medical instrument with shutter for sealing a test strip port

A medical instrument/analyzer for measuring a biological sample using a test strip. The instrument comprises: a housing with an exterior surface, an internal surface, and an interior volume; an analytical unit within the interior volume with a test strip mount; a test strip port between the exterior and the interior surfaces; a shutter configured for sealing the test strip port when closed, wherein the shutter comprises a test strip support aligned with the test strip port and mount when the shutter is in the open position, wherein the shutter has a first sealing surface, the test strip port has a second sealing surface, and the first sealing and second sealing surfaces are configured to mate in the closed position, wherein the shutter comprises a mechanism for moving between the open and the closed position; and an actuator configured for moving the shutter between the open and closed position.. ... Roche Diagnostics Operations Inc

04/19/18 / #20180106821

Storage module, method of operating a laboratory automation system and laboratory automation system

A storage module for a laboratory automation system, a method of operating a laboratory automation system, and a laboratory automation system are presented. Items used by laboratory stations are stored centrally in a storage module and can be transported to the laboratory stations using a laboratory sample distribution system.. ... Roche Diagnostics Operations Inc

04/19/18 / #20180105323

External packaging for safeguarding at least one package during transportation

A process for safeguarding a product during transportation comprises forming a package by surrounding a product with packaging material and accommodating the package in an external packaging that comprises a carrier element and a bag element. The carrier element includes an upper side including a border and a lower side opposite the upper side, wherein the lower side comprises a base. ... Roche Diagnostics Operations Inc

04/19/18 / #20180104683

Test element analysis system for the analytical examination of a sample

A test element analysis system for the analytical examination of a sample, a method for positioning a test element in a measuring device and a method for an analytical examination of a sample are disclosed. The test element analysis system comprises: a measurement device comprising a test element receptacle for receiving a test element at least partially, wherein the receptacle comprises a first part and a second part, the first part comprises a support surface for placement of the test element, the second part comprises an alignment pin for engagement with an alignment hole of the test element, the second part is movable relative to the first part in a direction essentially perpendicular to the support surface, the receptacle is configured to position the second part in at least three distinct positions relative to the first part comprising an intermediate position, a closed position, and an open position.. ... Roche Diagnostics Operations Inc

04/12/18 / #20180100826

Method and test element for electrochemically detecting at least one analyte in a sample of a body fluid

A method and test element for electrochemically detecting at least one analyte in a sample are provided, wherein the method comprises: a) providing at least one test element comprising at least one first electrode contacting a test chemistry and at least one second electrode, wherein a surface of the second electrode consists of silver metal; b) contacting both the first and second electrodes with the sample comprising chloride ions; c) applying a first voltage between the first electrode as a cathode and the second electrode as an anode with a voltage sufficient for forming a layer of silver chloride at the surface of the second electrode; d) applying a second voltage between the first electrode as the anode and the second electrode as the cathode; and e) determining an electrical signal between the first and the second electrodes, whereby the analyte in the sample comprising the chloride ions is detected.. . ... Roche Diagnostics Operations Inc

04/12/18 / #20180099812

Sample container handling device

A sample container handling device is presented. The device comprises a linear transport unit and a release unit comprising a release blade segment. ... Roche Diagnostics Operations Inc

04/05/18 / #20180095036

Quality control material, system and method

A quality control (qc) material for performing a qc procedure with respect to at least one detector is introduced. The qc material comprises at least one first qc substance and at least one second qc substance, wherein the first qc substance is interferable with the second qc substance or with the performance and/or lifetime of the detector and wherein the first qc substance is entrapped by carrier particles that prevent the first qc substance to interfere with the second qc substance or with the performance and/or lifetime of the detector. ... Roche Diagnostics Operations Inc

04/05/18 / #20180093267

Rotatable cartridge with a metering chamber for analyzing a biological sample

An automatic analyzer cartridge, spinnable around a rotational axis, has aliquoting and metering chambers, a connecting duct there between, and a vent connected to the metering chamber and nearer to the rotational axis than the metering chamber. The metering chamber has side walls that taper away from a central region. ... Roche Diagnostics Operations Inc

03/22/18 / #20180080949

Automated scheduler for laboratory equipment

A method is presented. The method includes receiving at least one order, generating one or more optimization problem instances using one or more resource descriptions of automated laboratory equipment, one or more protocol descriptions of the automated laboratory equipment, an objective function and the at least one order. ... Roche Diagnostics Operations Inc

03/15/18 / #20180075223

Point of care testing (poct) system

Disclosed are a system architecture and a method to enable workflow solutions via remote configuration services for the configuration management of point of care analyzers. According to particular embodiments, the disclosed system and method are configured to enable remote configuration services of point of care analyzers across different platforms.. ... Roche Diagnostics Operations Inc

03/15/18 / #20180074087

Laboratory sample distribution system, laboratory system and method of operating

A laboratory sample distribution system is presented. The laboratory sample distribution system comprises a plurality of container carriers. ... Roche Diagnostics Operations Inc

03/15/18 / #20180071740

Cartridge for dispensing particles and a reagent fluid

A method of dispensing a particle mixture and a reagent fluid cartridge are presented. The cartridge comprises a first reservoir partially filled with reagent fluid, a second reservoir partially filled with particles, a pumping chamber, a first pumping chamber conduit connecting the first reservoir and the pumping chamber, a second pumping chamber conduit connecting the second reservoir and the pumping chamber, an outlet for dispensing reagent fluid and particles from the cartridge, an outlet conduit connecting the outlet to the pumping chamber, and a valve sealing the outlet conduit. ... Roche Diagnostics Operations Inc

03/08/18 / #20180067141

Method of operating a laboratory sample distribution system, laboratory sample distribution system and laboratory automation system

A method of operating a laboratory sample distribution system is presented. The laboratory sample distribution system comprises a number of sample container carriers. ... Roche Diagnostics Operations Inc

03/08/18 / #20180067140

Signal offset determination and correction

A method for determining a background shift is presented. The method includes obtaining a plurality of optical measurement sets of a sample taken by a sample analyzer at different points in time. ... Roche Diagnostics Operations Inc

03/08/18 / #20180067139

System and method for storing and retrieving vessel holders

An automated system and method for storing/retrieving vessel holders is presented. A first storage compartment comprises first storage sections. ... Roche Diagnostics Operations Inc

03/01/18 / #20180062857

Method for authenticating an instrument for processing a biological sample or reagent and system comprising an instrument for processing a biological sample or reagent

A method for authenticating an instrument for processing a biological sample or reagent is disclosed. The method comprises generating a pin code by the instrument, entering the pin code and identification data associated with the instrument in a database of an electronic device, verifying the pin code and identification data at the electronic device, transmitting an authentication certificate to the instrument if the pin code and identification data correspond to target data stored in the database, installing the authentication certificate on the instrument, whereby the instrument is registered with the electronic device, and using the authentication certificate for an encrypted communication between the instrument and the electronic device. ... Roche Diagnostics Operations Inc

03/01/18 / #20180056301

Test tube carrier

A test tube carrier for transporting test tubes in a laboratory automation system is presented. The test tube carrier comprises a base body and at least three centering fingers attached to the base body. ... Roche Diagnostics Operations Inc

02/01/18 / #20180029731

Recapper, laboratory automation system, and method of recapping a sample container

A recapper for placing foils on laboratory sample containers is presented. The foils are brought on the sample container by a lever arrangement that is rotated around a vertical axis.. ... Roche Diagnostics Operations Inc

01/11/18 / #20180010990

Automated system for processing particles

A method for processing particles contained in a liquid biological sample is presented. The method uses a rotatable vessel for processing particles contained in a liquid biological sample. ... Roche Diagnostics Operations Inc

01/04/18 / #20180003710

Method of assessing rheumatoid arthritis by measuring anti-ccp and anti-pik3cd

The present invention relates to a method aiding in the assessment of rheumatoid arthritis (“ra”). The method is used in assessing ra in vitro. ... Roche Diagnostics Operations Inc








ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009



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