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Rush University Medical Center patents


Recent patent applications related to Rush University Medical Center. Rush University Medical Center is listed as an Agent/Assignee. Note: Rush University Medical Center may have other listings under different names/spellings. We're not affiliated with Rush University Medical Center, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "R" | Rush University Medical Center-related inventors


 new patent  Compositions and methods for treating cancer

One aspect of the invention provides a method for treating a cancer including administering to a subject in need of such treatment a composition including a therapeutically effective amount of an antibody directed against p40 monomer or an immunologically active fragment thereof. In various embodiments, the antibody is a polyclonal, monoclonal, human, humanized, and chimeric antibody; a single chain antibody or an epitope-binding antibody fragment. ... Rush University Medical Center

Lipid markers for early diagnosis of breast cancer

Methods for measuring a panel of biomarkers in a subject suspected of having breast cancer are provided. The methods include obtaining a biological sample from the subject and determining a measurement for a panel of biomarkers in the biological sample, the panel comprising at least 5 biomarkers selected from the group comprising lpc(18:3), lpc(20:2), lpc(20:1), lpc(20:0), pc(32:1), pc(34:4), pc(38:3), pc(40:5), pc(40:3), pc(44:11), epc(32:2), epc(38:3), c19:1 ce, c19:0 ce, and c20:0 ce, wherein the measurement comprises measuring a level of each of the at least 5 biomarkers.. ... Rush University Medical Center

Algorithm, data pipeline, and method to detect inaccuracies in comorbidity documentation

Systems and methods for detecting inaccuracies in comorbidity documentation are provided. An example method can include retrieving patient data from a hospital records database, generating a first data structure representing a list of patient identifiers, retrieving patient symptom data for each patient identifier listed in the first data structure, generating, a second data structure by assigning the retrieved patient symptom data to the eligible patients represented in the first data structure, retrieving, a plurality of lookup tables, generating a third data structure by applying the lookup tables to the second data structure to assign a cc or a mcc value to at least one unique patient identifier of the second data structure, and storing the third data structure to the memory. ... Rush University Medical Center

Implant removal devices and methods of use thereof

Various aspects of the present invention provide an apparatus and a method of removing an orthopedic implant from a patient. In one embodiment, the method includes cycling the temperature of at least a portion of the orthopedic implant between a first temperature and a second temperature that differs from the first temperature. ... Rush University Medical Center

Electrode placement and treatment system and method of use thereof

Certain aspects of the invention provide a system and a method for treating an epileptic condition or a tumor of the brain. In one embodiment, the method of treating the epileptic condition includes acquiring inter- and post-ictal imaging profiles and from the brain of the patient and determining an ictal propagation pathway based on the profiles. ... Rush University Medical Center

Compositions and methods for treating lysosomal disorders

One aspect of the invention provides a method for treatment of a lysosomal storage disorder. The method may include administering to a subject in need of such treatment a composition including a therapeutically effective amount of an agent that mediates upregulation of transcription factor eb. ... Rush University Medical Center

Saliva collection kit and procedure for validated home assessment of dim light melatonin onset

Methods and kits are provided for collecting samples for assessment of circadian timing in a non-clinical environment. The methods include monitoring light exposure of a subject and placing a first biological sample in a first sample vial, wherein the first biological sample is obtained in the non-clinical environment in dim light comprising light less than about 50 lux and monitoring the use of the first sample vial with a monitoring device. ... Rush University Medical Center

Composition and method for treating neuronal ceroid lipofuscinosis

Provided herein are methods for treatment of a neurodegenerative disease, such as neuronal ceroid lipofuscinosis including administering to a subject in need of such treatment a composition comprising a therapeutically effective amount of an agent that mediates upregulation of tpp1.. . ... Rush University Medical Center

Food/beverage vending machine with adjustable delivery delays

A method and system for encouraging the selection of healthy products with a vending machine are provided. The method includes providing a vending machine that displays an inventory of products. ... Rush University Medical Center

Assays and compounds to treat kidney diseases

Methods of treating kidney disease and protecting podocytes from injury are provided. Methods of screening agents for the treatment of kidney disease are also provided. ... Rush University Medical Center

Methods for preventing or treating osteoarthritis

One aspect of the invention provides a method for treating or preventing the development of osteoarthritis by administering to a subject in need of such treatment a composition including a therapeutically effective amount of an anti-fibrotic agent. In various embodiments, the anti-fibrotic agent is 5-methyl-1-phenylpyridin-2-one, tranilast, gamma-glutamyl transpeptidase inhibitor, fasudil, cc-930, t-5524, rosiglitazone, tocilizumab, e5564, tak-242, gkt136901 or bosentan.. ... Rush University Medical Center

Vector delivery-based microbicides

A new class of anti-microbial agents and methods for preventing or reducing the risk of sexually transmitted infections and/or diseases is provided. Preferably, these anti-microbial agents are also contraceptive and, thus, also prevent or reduce the risk of unplanned pregnancies. ... Rush University Medical Center

Geographic utilization of artificial intelligence in real-time for disease identification and alert notification

Systems and methods for generating a diagnosis are provided. In some aspects, a computing device receives medical information for a patient, wherein each medical information item in the medical information comprises a date, a source, and a medical state. ... Rush University Medical Center

Micrornas as new therapeutic targets for the prevention and/or treatment of retinopathy

Methods and compositions are disclosed to identify plasma and vitreous microrna (mirna) signatures of diabetic retinopathy (dr), and then as diagnostic biomarkers for the onset and progression of dr.. . ... Rush University Medical Center

05/18/17 / #20170137813

Mirnas as novel therapeutic targets and diagnostic biomarkers for parkinson's disease

The disclosure provides pharmaceutical compositions including an oligonucleotide that down-regulates the over-expression of at least one mirna of seq id nos: 1-283. The oligonucleotide may be complementary to the nucleotide sequence of at least one of seq id nos: 1-283, or hybridizes under stringent conditions to a nucleotide sequence of at least one of seq id nos: 1-283. ... Rush University Medical Center

05/11/17 / #20170129923

Grb-ehitsn inhibitory peptides

Fusion peptides and methods of inhibiting grb-ehitsn or a fragment thereof are provided. The fusion peptides include an npf peptide and a cell-permeable peptide operably connected thereto. ... Rush University Medical Center

04/27/17 / #20170112585

Anchoring for non-retainable foreign objects

A kit and/or method for use during surgery is configured to decrease the risk of accidental retention of foreign objects, such as surgical items or medical devices, used in surgery inside of a patient after the surgery is completed. Specifically, illustrative kits may include, but not be limited to, a combination of one or more foreign objects, an anchoring member attached to a point outside of the patient or surgical field, and at least one or more connection members connecting the foreign objects to the anchoring member. ... Rush University Medical Center

04/13/17 / #20170100127

Catheter lumen partitioner

A device and methods for treating an aneurysm includes a catheter capable of insertion into a body to be positioned adjacent the aneurysm, the catheter including a distal end and an operator end opposite the distal end. The catheter forms a circular pathway extending between the distal end and the operator end. ... Rush University Medical Center

03/30/17 / #20170086682

Vascular impedance measuring device and method of determining impedance

A vascular impedance measuring device may comprise a processing component capable of processing raw pressure and flow wave data and a pressure measuring component capable of providing pressure wave data from a specified point in a vessel and forwarding the pressure wave data to the processing component. The device may further include a flow measuring component capable of providing flow wave data from the specified point or a point near the specified point in the vessel and forwarding the flow wave data to the processing component. ... Rush University Medical Center

03/02/17 / #20170056536

Electrochemical manipulation of implants

The present invention generally relates to systems and methods of treating microbial growth on a conducting surface, for example, the conducting surface of an implanted medical device. One embodiment of the method includes applying a electrical current through the conducting surface and a counter electrode. ... Rush University Medical Center

01/19/17 / #20170014484

Methods of promotion of healing of diabetic wounds

A method of treating a wound in a diabetic patient is provided. The method includes administering a therapeutically effective amount of chemokine (c-c motif) ligand 2 (ccl2) to a wound site. ... Rush University Medical Center








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