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Saint Louis University patents


Recent patent applications related to Saint Louis University. Saint Louis University is listed as an Agent/Assignee. Note: Saint Louis University may have other listings under different names/spellings. We're not affiliated with Saint Louis University, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "S" | Saint Louis University-related inventors


Compositions and methods for diagnosing and treating endometriosis-related infertility

. . Disclosed are methods of diagnosing and treating endometriosis, and in particular, endometriosis-associated infertility.. . ... Saint Louis University

Antagonists of gpr160 for the treatment of pain

The disclosure provides methods and compositions for inhibiting pain by administering a gpr160 antagonist to a subject in need thereof. Also provided are methods of using gpr160 antagonists in combination with other pain therapies.. ... Saint Louis University

Inhibitors of nucleotidyl transferases and use in herpes and hepatitis viral infections therefor

The present disclosure relates to identification of inhibitors of hepatitis and herpesvirus replication including compounds of the formula: wherein the variables are as defined herein. Also provided are methods of treatment using agents so identified.. ... Saint Louis University

Mask free methods of depositing compositions to form heterostructures

The present disclosure provides methods of preparing heterostructures of two or more transition metal dichalcogenides on a surface in a pattern in which the method does not require a mask or blocking agent to create a pattern on the surface. Also provided herein are ink compositions which are used in the methods described herein and include precursor materials that generate these transition metal dichalcogenides.. ... Saint Louis University

Thrombin-thrombomodulin fusion proteins as protein c activators

Compositions and methods for regulating the blood coagulation pathway are disclosed. More particularly, the present disclosure relates to thrombin-thrombomodulin fusion proteins, vectors, host cells and methods for preparing the thrombin-thrombomodulin fusion proteins. ... Saint Louis University

Method for template-dependent multiple displacement amplification

Provided herein are methods for template-dependent multiple displacement amplification (tdmda) that preferably use 5′ blocked pentamer primers.. . ... Saint Louis University

Reduced immunogenic proteins for lysosomal storage disorders

. . Disclosed are methods and compositions for reduced immunogenic proteins used in enzyme replacement therapy for lysosomal storage disorders. More specifically disclosed are genetically engineered variants of n-acetylgalactosamine-6-sulfatase (galns), which are less immunogenetic then wild-type galns, but maintain enzymatic activity, and may be used to treat mucopolysaccharidosis iva (morquio a disease, mps iva).. ... Saint Louis University

Inhibition of dux4 expression using bromodomain and extra-terminal domain protein inhibitors (beti)

The use of beti as a potential treatment for fshd is provided. Specifically, the use of beti, and particularly selective beti for brd4, are shown to inhibit dux4 expression which is expected to result in a decrease in the severity of symptoms of fshd. ... Saint Louis University

Molecular biosensors capable of signal amplification

The present invention provides molecular biosensors capable of signal amplification, and methods of using the molecular biosensors to detect the presence of a target molecule.. . ... Saint Louis University

Diagnosis of leukocyte-mediated disease and halogen gas exposure

Described are glutathione adducts of fatty aldehydes (fald-gsh) and methods useful in the detection of fald-gsh in the identification of pathologies associated with leukocyte-mediated disease conditions, including eosinophil and neutrophil activation. Thus, the present disclosure provides methods of diagnosing a subject as having or being at risk of developing a leukocyte-mediated disease (lmd) comprising (a) detecting the level of glutathione adducts of 2-halofatty aldehydes (fald-gsh) in a sample; (b) comparing the amount of fald-gsh with a control or standard reflective of diseased and/or healthy levels of fald-gsh; and (c) diagnosing the subject as having or being at risk of developing lmd if the level of fald-gsh in the sample is higher than the control or standard.. ... Saint Louis University

Hbv rnase h purification and enzyme inhibitors

Provided herein are methods for the obtention of an active hbv rnaseh preparation and its use in screening methods to identify potential inhibitors of the enzyme for possible use as therapeutic agents. Also provided are methods of treatment using agents identified according to the screen.. ... Saint Louis University

Methods of transferring carbon nanotubes on a hydrogel

Disclosed herein are methods for transferring carbon nanotubes on a hydrogel scaffold. Carbon nanotubes are formed on a substrate and directly transferred onto a hydrogel surface. ... Saint Louis University

A3 adenosine receptor agonists

Disclosed are compounds of the formula (i) and (ii) which are a3 adenosine receptor agonists, pharmaceutical compositions comprising such compounds, and a method of use of these compounds, wherein x, y, z, r2-r6, and r103-r106 are as defined in the specification. These compounds are selective to the a3 receptor, and are contemplated for use in the treatment or prevention of a number of diseases or conditions, for example, neuropathic pain.. ... Saint Louis University








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