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Sarepta Therapeutics Inc patents (2016 archive)


Recent patent applications related to Sarepta Therapeutics Inc. Sarepta Therapeutics Inc is listed as an Agent/Assignee. Note: Sarepta Therapeutics Inc may have other listings under different names/spellings. We're not affiliated with Sarepta Therapeutics Inc, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "S" | Sarepta Therapeutics Inc-related inventors


Functionally-modified oligonucleotides and subunits thereof

Functionally-modified oligonucleotide analogues comprising modified intersubunit linkages and/or modified 3′ and/or 5′-end groups are provided. The disclosed compounds are useful for the treatment of diseases where inhibition of protein expression or correction of aberrant mrna splice products produces beneficial therapeutic effects.. ... Sarepta Therapeutics Inc

Exon skipping compositions for treating muscular dystrophy

. . Antisense molecules capable of binding to a selected target site in the human dystrophin gene to induce exon 44 skipping are described.. . ... Sarepta Therapeutics Inc

Antisense composition and method for treating muscle atrophy

A method and compound for treating skeletal muscle mass deficiency in a human subject are disclosed. The composition is an oligomer of morpholino subunits and phosphorus-containing intersubunit linkages joining a morpholino nitrogen of one subunit to a 5′ exocyclic carbon of an adjacent subunit, contains between 10-40 nucleotide bases, has a base sequence effective to hybridize to an expression-sensitive region of processed or preprocessed human myostatin rna transcript, identified, in its processed form, by seq id no:6, and is capable of uptake by target muscle cells in the subject. ... Sarepta Therapeutics Inc

Antibacterial antisense oligonucleotide and method

A method for enhancing, by at least 10 fold, the antibacterial activity of an antisense oligonucleotide composed of morpholino subunits linked by phosphorus-containing intersubunit linkages. The method includes one or both of: conjugating an arginine-rich carrier to a 3′ or 5′ end of the oligonucleotide and modifying the oligonucleotide to contain 20%-50% intersubunit linkages that are positively charged at physiological ph. ... Sarepta Therapeutics Inc

Peptide oligonucleotide conjugates

Oligonucleotide analogues conjugated to carrier peptides are provided. The disclosed compounds are useful for the treatment of various diseases, for example diseases where inhibition of protein expression or correction of aberrant mrna splice products produces beneficial therapeutic effects.. ... Sarepta Therapeutics Inc

Exon skipping compositions for treating muscular dystrophy

Antisense molecules capable of binding to a selected target site in the human dystrophin gene to induce exon 53 skipping are described.. . ... Sarepta Therapeutics Inc

Multiple exon skipping compositions for dmd

Provided are antisense molecules capable of binding to a selected target site in the human dystrophin gene to induce exon skipping, and methods of use thereof to treat muscular dystrophy.. . ... Sarepta Therapeutics Inc

Multiple exon skipping compositions for dmd

Provided are antisense molecules capable of binding to a selected target site in the human dystrophin gene to induce exon skipping, and methods of use thereof to treat muscular dystrophy.. . ... Sarepta Therapeutics Inc

Multiple exon skipping compositions for dmd

Provided are antisense molecules capable of binding to a selected target site in the human dystrophin gene to induce exon skipping, and methods of use thereof to treat muscular dystrophy.. . ... Sarepta Therapeutics Inc








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