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Senomyx Inc patents


Recent patent applications related to Senomyx Inc. Senomyx Inc is listed as an Agent/Assignee. Note: Senomyx Inc may have other listings under different names/spellings. We're not affiliated with Senomyx Inc, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "S" | Senomyx Inc-related inventors


Compounds useful as modulators of trpm8

The present disclosure relates to compounds which are useful as cooling sensation compounds.. . ... Senomyx Inc

Screening assays to identify compounds which modulate t1r associated taste modalities which eliminate false positives

. . This invention relates to assays which screen for compounds that modulate taste elicited by the t1r2/t1r3 sweet taste receptor which include a novel counter screen to eliminate false positives. In addition, the invention contemplates assays which screen for compounds that modulate taste elicited by the t1r1/t1r3 umami taste receptor which include a novel counter screen to eliminate false positives. ... Senomyx Inc

T2r taste receptors and genes encoding same

Newly identified mammalian taste-cell-specific g protein-coupled receptors and the genes encoding said receptors are described. Specifically, t2r taste g protein-coupled receptors that are believed to be involved in bitter taste sensation, and the genes encoding the same, are described, along with methods for isolating such genes and for isolating and expressing such receptors. ... Senomyx Inc

T1r taste receptors and genes encoding same

Newly identified mammalian taste-cell-specific g protein-coupled receptors, and the genes and cdna encoding said receptors are described. Specifically, t1r g protein-coupled receptors active in taste signaling, and the genes and cdna encoding the same, are described, along with methods for isolating such genes and for isolating and expressing such receptors. ... Senomyx Inc

Sweetener composition

Formulations comprising one or more sweetener and one or more flavor modifying compound are provided herein, wherein the formulation is provided for use in ingestible products, such as food or beverage products or pharmaceutical, or for use in non-comestible products, such as cosmetic or hygienic products. The formulations include combinations of any one or more sweetener in combination with any one or more flavor modifying compound described or referenced herein.. ... Senomyx Inc

Identification of bitter ligands that specifically activate human t2r receptors and related assays for identifying human bitter taste modulators

The present invention relates to the discovery that specific human taste receptors in the t2r taste receptor family respond to particular bitter compounds. Also, the invention relates to the discovery of specific ht2r9 alleles and their disparate activity in functional assays with the same biter ligands. ... Senomyx Inc

T1r hetero-oligomeric taste receptors, cell lines that express said receptors, and taste compounds

The invention relates to compounds that specifically bind a t1r1/t1r3 or t1r2/t1r3 receptor or fragments or sub-units thereof. The present invention also relates to the use of hetero-oligomeric and chimeric taste receptors comprising t1r1/t1r3 and t1r2/t1r3 in assays to identify compounds that respectively respond to umami taste stimuli and sweet taste stimuli. ... Senomyx Inc

Compounds useful as modulators of trpm8

The present invention includes compounds useful as modulators of trpm8, such as compounds of formulae (ia), (ib) and (ic), and the subgenus and species thereof; personal products containing those compounds; and the use of those compounds and the personal products, particularly the use of increasing or inducing chemesthetic sensations, such as cooling or cold sensations.. . ... Senomyx Inc

Rationale, methods, and assays for identifying human and non-human primate taste specific genes and use thereof in taste modulator and therapeutic screening assays

. . This invention relates to novel rationale and methods for identifying human and primate taste-specific genes, including genes involved in salty taste perception, especially human salty taste perception, but also genes involved in sweet, bitter, umami, and sour taste perception, and genes involved in other taste cell or taste receptor related activities such as digestive function and digestive related diseases, taste cell turnover, immunoregulation of the oral and digestive tract, and metabolic regulation such as in diabetes and obesity, the genes identified using these methods, and assays for identifying taste modulators (enhancers or blockers) and potential therapeutics using these genes. These compounds have potential application in modulating (enhancing or blocking) taste perception, especially salty taste perception and as potential therapeutics. ... Senomyx Inc

Sweetener composition

Formulations comprising one or more sweetener and one or more flavor modifying compound are provided herein, wherein the formulation is provided for use in ingestible products, such as food or beverage products or pharmaceutical, or for use in non-comestible products, such as cosmetic or hygienic products.. . ... Senomyx Inc

T1r hetero-oligomeric taste receptors

. . Newly identified mammalian taste-cell-specific g protein-coupled receptors which function as hetero-oligomeric complexes in the sweet taste transduction pathway, and the genes and cdna encoding said receptors are described. Specifically, t1r g protein-coupled receptors active in sweet taste signaling as hetero-oligomeric complexes, and the genes and cdna encoding the same, are described, along with methods for isolating such genes and for isolating and expressing such receptors. ... Senomyx Inc

Electrophysiological assays using oocytes that express human enac and the use of phenamil to improve the effect of enac enhancers in assays using membrane potential reporting dyes

. . In one aspect, the present invention relates to a mammalian cell-based high-throughput assay for the profiling and screening of human epithelial sodium channel (henac) cloned from a human kidney c-dna library and is also expressed in other tissues including human taste tissue. The present invention further relates to amphibian oocyte-based medium-throughput electrophysiological assays for identifying human enac modulators, preferably enac enhancers. ... Senomyx Inc

Method of improving stability of sweet enhancer and composition containing stabilized sweet enhancer

Disclosed herein are stabilized sweet enhancer compositions. Also disclosed herein are methods for stabilizing sweet enhancers.. ... Senomyx Inc

High intensity sweeteners

Disclosed herein are compounds having structural formula (i), or salts thereof. These compounds are useful as sweet tasting agents and/or sweetness enhancers. ... Senomyx Inc

04/20/17 / #20170105432

Sweetener and flavor enhancer formulations

Formulations comprising one or more sweetener and one or more flavor modifying compound are provided herein, wherein the formulation is provided for use in ingestible products, such as food or beverage products or pharmaceutical, or for use in non-comestible products, such as cosmetic or hygienic products.. . ... Senomyx Inc

04/06/17 / #20170096418

Compounds useful as modulators of trpm8

The present disclosure relates to compounds which are useful as cooling sensation compounds.. . ... Senomyx Inc

03/30/17 / #20170087199

Compositions for delivering a cooling sensation

Disclosed herein are compositions comprising combinations of one or more cooling agents with additional cooling agents, inactive drug ingredients, food additives, antimicrobials, corticosteroids, compounds known to be used in the production of home, personal care, and pet care products, and smokable materials. Further disclosed are foodstuffs, medicaments, personal care products, home products, pet care products, warming compositions, probiotic supplements and smoking articles produced by incorporating the disclosed combinations.. ... Senomyx Inc

02/16/17 / #20170042196

Use of umami compounds to enhance saltiness

Provided herein are umami compounds for use as salt-enhancing agents, and for use in enhancing the flavor of reduced sodium products or sodium-free products and increasing the palatability of products that may have reduced sodium content. Also provided herein are methods for modulating the perceived saltiness of a product by adding salt-enhancing compounds to the product.. ... Senomyx Inc








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