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Sunnybrook Research Institute patents


Recent patent applications related to Sunnybrook Research Institute. Sunnybrook Research Institute is listed as an Agent/Assignee. Note: Sunnybrook Research Institute may have other listings under different names/spellings. We're not affiliated with Sunnybrook Research Institute, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "S" | Sunnybrook Research Institute-related inventors


Systems and methods for prediction of tumor response to chemotherapy using pre-treatment quantitative ultrasound parameters

Systems and methods for using quantitative ultrasound (“qus”) techniques to generate imaging biomarkers that can be used to assess a prediction of tumor response to different chemotherapy treatment regimens are provided. For instance, the imaging biomarkers can be used to subtype tumors that have resistance to certain chemotherapy regimens prior to drug exposure. ... Sunnybrook Research Institute

Systems and methods for performing transcranial ultrasound therapeutic and imaging procedures

Systems and methods are provided for performing transcranial diagnostic procedures using a transcranial ultrasound transducer array. The array elements are positioned and oriented such that far field regions respectively associated therewith spatially overlap within the brain of a patient. ... Sunnybrook Research Institute

Data display and processing algorithms for 3d imaging systems

The present disclosure provides methods to process and/or display data collected using 3d imaging probes. The methods include: a) methods for mapping a single 2d frame onto a 3d representation of a volume; b) methods for dynamically updating portions of a 3d representation of a volume with a high temporal resolution, while leaving the remainder of the volume for contextual reference; c) methods for registering volumetric datasets acquired with high temporal resolution with volumetric datasets acquired with relatively low temporal resolution in order to estimate relative displacement between the datasets; and d) methods for identifying structures within a volume and applying visual cues to the structures in subsequent volumes containing the structures.. ... Sunnybrook Research Institute

Method for registering pre-operative images of a subject to an ultrasound treatment space

Systems and methods for registering pre-operative medical images, such as computed tomography (“ct”) images, to the coordinate space of an ultrasound treatment system are provided. The registration is generally based on minimizing distances between locations associated with an anatomical feature, as identified from the medical images, and spherical surfaces defined by time-of-flight measurements for ultrasound data acquired from the anatomical feature by transducer elements. ... Sunnybrook Research Institute

Method for treating cancer

The present disclosure relates to a method of treating prostate cancer comprising administering to a subject in need thereof a therapeutically effective amount of a vasopressin analogue.. . ... Sunnybrook Research Institute

System and method for detection of collagen using magnetic resonance imaging

Systems and methods are provided for detecting collagen within tissue using magnetic resonance imaging. In some embodiments, pulse sequences are employed to measure signals at multiple te values including ultra-short echo times, and the te dependence of the measured signal is fitted to a mathematical function including at least two decay terms, where the first (initial) decay term is modulated and is associated with the presence of collagen. ... Sunnybrook Research Institute

System and method for device tracking via magnetic resonance imaging with light-modulated magnetic susceptibility markers

Described here are systems and methods for using a laser-induced demagnetization of magnetic particles disbursed in a tracking marker to generate variable susceptibility effects that can be imaged with magnetic resonance imaging (“mri”). As one example, laser power is delivered to nickel particles using fiber optics. ... Sunnybrook Research Institute

System and method for producing distortion free magnetic resonance images using dual-echo echo-planar imaging

Described here are systems and methods for correcting magnetic resonance data for off-resonance effects arising from the use of a multi-echo echo planar imaging (“epi”) pulse sequence. Reference data are acquired, from which phase maps are computed in a distorted coordinate space associated with geometric distortions associated with the multi-echo epi acquisition. ... Sunnybrook Research Institute

Pressing apparatus for magnetic resonance imaging and spectroscopy

A magnetic resonance (mr) apparatus, the mr apparatus including a tissue pressing surface having one or more mr coil elements, the pressing surface being configured and sized to selectively indent a portion of an exterior tissue of a subject when a physical force is applied to the indenting substrate thereby reducing a distance between the one or more mr coil elements and a structure of interest located inside the subject.. . ... Sunnybrook Research Institute

Systems and methods for generating an imaging biomarker that indicates detectability of conspicuity of lesions in a mammorgraphic image

Systems and methods for generating imaging biomarkers that indicate detectability or conspicuity of lesions that may be present in mammographic images are provided. In general, a task-based measure of a signal-to-noise ratio (“snr”) measurement of a detection task is computed over a number of small regions-of-interest (“rois”) in an image, and the computed parameter is used to predict what detection rates should be if a lesion was present in the image. ... Sunnybrook Research Institute

Combination

The present invention relates to a method of treating breast cancer in a human and to pharmaceutical combinations useful in such treatment. In particular, the method relates to a breast cancer treatment method that includes administering 5-[[4-[(2,3-dimethyl-2h-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methylbenzenesulfonamide, or a pharmaceutically acceptable salt thereof, and (s)-10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1h-pyrano[3′,4′:6,7] indolizino [1,2-b]quinoline-3,14-(4h,12h)-dione, or a pharmaceutically acceptable salt thereof, to a human in need thereof.. ... Sunnybrook Research Institute








ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009



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