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Surmodics Inc patents


Recent patent applications related to Surmodics Inc. Surmodics Inc is listed as an Agent/Assignee. Note: Surmodics Inc may have other listings under different names/spellings. We're not affiliated with Surmodics Inc, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "S" | Surmodics Inc-related inventors


Low-friction sealing devices

Aspects herein relate to a low-friction septum for providing a leak-resistant seal for use in a vascular access device. In an embodiment, a device for vascular access hemostasis is included having an enclosure defining a cavity and configured to at least partially receive a medical device. ... Surmodics Inc

Hydrophobic active agent particle coatings and methods for treatment

Drug delivery coatings and devices including the same are described herein. The drug delivery coating has a first coated layer with non-ionic polymer and photogroups, a second coated layer with acid polymer in contact and hydrogen bonded with the first layer, particles with hydrophobic therapeutic agent, and cationic agent. ... Surmodics Inc

Delivery of hydrophobic active agents from hydrophilic polyether block amide copolymer surfaces

Embodiments of the invention include drug delivery coatings and devices including the same. In an embodiment, a drug delivery coating is included herein having a base polymeric layer, the base polymeric layer including a hydrophilic polyether block amide copolymer and having a hydrophilic surface. ... Surmodics Inc

Insertable medical devices having microparticulate-associated elastic substrates and methods for drug delivery

The present invention provides insertable medical devices having elastic surfaces associated with bioactive agent-containing microparticulates and a coating material. Upon expansion of the elastic surfaces the microparticulates can be released to a subject.. ... Surmodics Inc

Interventional balloon system including deflation guidance

A balloon system includes a balloon catheter extending from a proximal end portion to a distal end portion. The balloon catheter includes an inflation lumen therein. ... Surmodics Inc

Lubricious insertion tools for medical devices and methods for using

The disclosure provides insertion tools and articles that facilitate entry of a medical device, such as a balloon catheter, into the body, and that can provide advantages in terms of balloon insertion, safety, and drug delivery. The insertion tool includes a tubular portion that accommodates a balloon portion of a balloon catheter, and one or more separation margin(s) in the wall of the tubular portion or one or more split(s) in the tubular wall. ... Surmodics Inc

Solvent methods for preparing crystalline macrolide particulates, compositions, and articles containing particulates

The invention provides therapeutic particulates including a macrolide, such as rapamycin, in solid state crystalline form, having a size of 20 μm or less, or 10 μm or less. The particulates are formed in one method by preparing a composition with a macrolide and first (e.g., xylene) and second (e.g., an alcohol, acetone, or acetonitrile) solvents. ... Surmodics Inc

Apparatus and methods for coating medical devices

Embodiments herein include apparatus and methods for coating medical devices. In an embodiment, a coating apparatus is included having a coating application unit including a movement restriction structure, a fluid applicator having a lengthwise major axis, a fluid distribution bar having a body angled with respect to the major lengthwise axis of the fluid applicator between 0 and 20 degrees, a rotation mechanism and an axial motion mechanism. ... Surmodics Inc

Insertion tools for medical devices and methods for using

The disclosure provides insertion tools and articles that facilitate entry of a medical device, such as a balloon catheter, into the body. In embodiments the insertion tools have an elongate hollow body (50) that is able to protect a portion of a medical device, such as a balloon of a balloon catheter, during an insertion procedure. ... Surmodics Inc

Hemostasis sealing device with constriction ring

Aspects herein relate to a medical device for providing a leak-resistant seal for use in a vascular access device. In various embodiments, a device for vascular access hemostasis is included. ... Surmodics Inc

Lubricious medical device coating with low particulates

Embodiments of the invention include lubricious medical device coatings. In an embodiment the invention includes a coating for a medical device including a first layer comprising polyvinylpyrrolidone derivatized with a photoreactive group; and a first cross-linking agent comprising at least two photoreactive groups; a second layer disposed on the first layer comprising polyvinylpyrrolidone derivatized with a photoreactive group; a second cross-linking agent comprising at least two photoreactive groups; and a polymer comprising polyacrylamide, the polymer derivatized with at least one photoreactive group. ... Surmodics Inc

Localized treatment of tissues through transcatheter delivery of active agents

Embodiments herein include catheters and methods for the localized treatment of tissues through transcatheter delivery of active agents. In an embodiment, a method herein can include inserting a catheter into the lumen of a blood vessel. ... Surmodics Inc

Delivery system for active agent coated balloon

Embodiments herein include delivery systems for active agent coated balloons and related methods. In an embodiment, a delivery system can include a tunneling sheath and a balloon catheter. ... Surmodics Inc

Two-part insertion tool and methods

Embodiments herein include an insertion tool for inserting a medical device into another medical device, such as a hemostasis sealing valve, and related methods. In an embodiment, an insertion tool includes a guide sheath and a protection tube. ... Surmodics Inc

10/05/17 / #20170281831

Lubricious coating for medical device

Embodiments of the disclosure include lubricious coatings. In an embodiment the disclosure includes a lubricious coating for a medical device including an acrylic acid polymer, an acrylamide copolymer comprising at least one photoreactive group, and a cross-linking agent comprising at least two photoreactive groups. ... Surmodics Inc

10/05/17 / #20170281557

Drug-containing particulate composition with cationic agent, associated medical devices, and methods for treatment

The disclosure provides bioactive agent-containing particulates that include bioactive agent, biocompatible polymer, negatively charged groups, and a cationic agent. The particulates can be associated with a medical device, such as a balloon catheter, which can be used to move the particulates to a treatment site. ... Surmodics Inc

08/10/17 / #20170224876

Article coatings including oligomerized polyphenol layer and biological methods of use

Embodiments of the disclosure include coatings comprising an oligomerized polyphenol layer. The oligomerized polyphenol layer can be used as an intermediate coated layer on a medical device that hydrogen bonds to a synthetic or natural polymer, which in turn can be used as a top coat or further associated with another coated layer. ... Surmodics Inc

06/29/17 / #20170182224

Lubricious coatings with surface salt groups

Embodiments herein include coated medical devices and coatings with salt groups. In an embodiment, a coated medical device is included, the coated medical device including a substrate and a polymeric layer disposed over the substrate. ... Surmodics Inc

06/08/17 / #20170157372

Method and apparatus for coating balloon catheters

A coating apparatus for coating the balloon portion of a balloon catheter is described. The coating apparatus includes a rotatable member in which the catheter portion of the balloon catheter is mounted and fixed, and which causes rotation of the balloon catheter. ... Surmodics Inc

04/27/17 / #20170112973

Delivery of hydrophobic active agent particles

Embodiments of the invention include drug delivery coatings and devices including the same. In an embodiment, the invention includes a drug delivery coating including a polymeric layer. ... Surmodics Inc

04/06/17 / #20170095559

Composition for intravascular delivery of therapeutic composition

The present invention relates to a pharmaceutical composition for intravascular delivery of a therapeutic agent, such as paclitaxel, rapamycin, or an analog thereof. The composition includes the therapeutic agent and a biocompatible solvent, such as glycofurol. ... Surmodics Inc

03/16/17 / #20170072129

Hemodialysis catheter sleeve

A hemodialysis vascular access device includes a proximal end sized and shaped to sealably couple to a hemodialysis catheter, a movable structure coupled to the proximal end, a fixation structure coupled to the movable region and sized and shaped for fixation on a patient, an elongated sleeve coupled to the fixation structure and sized and shaped for insertion into a patient's vasculature, and a valve at a distal end of the internal lumen. When a hemodialysis catheter is inserted into the device and coupled to the proximal end, distal movement of the proximal end relative to the fixation structure biases a distal end of the hemodialysis catheter from a position inside the elongated sleeve through a valve out of the device and into the patient's blood.. ... Surmodics Inc

03/16/17 / #20170072057

Composition and method for delivery of hydrophobic active agents

Disclosed herein is a delivery composition for administering a hydrophobic active agent. In one embodiment, a delivery composition for local administration of a hydrophobic active agent to a tissue or organ of a patient is disclosed. ... Surmodics Inc

01/26/17 / #20170022375

Photoactivatable crosslinker

Described herein is a degradable linking agent of formula photo1-lg-photo2, wherein photo1 and photo2 independently represent at least one photoreactive group and lg represents a linking group comprising one or more silicon atoms or one or more phosphorous atoms. The degradable linking agent includes a covalent linkage between at least one photoreactive group and the linking group, wherein the covalent linkage between at least one photoreactive group and the linking group is interrupted by at least one heteroatom. ... Surmodics Inc

01/12/17 / #20170007745

Coatings with crystallized active agent(s) and methods

The present invention relates to coatings with crystallized active agent(s) and related methods. In an embodiment, the invention includes a method for coating a medical device including selecting a solvent and a polymer, selecting a concentration of an active agent of at least a certain amount of saturation, forming a coating composition having the selected concentration of the active agent, and applying the coating composition to the medical device. ... Surmodics Inc








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