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Takara Bio Inc patents


Recent patent applications related to Takara Bio Inc. Takara Bio Inc is listed as an Agent/Assignee. Note: Takara Bio Inc may have other listings under different names/spellings. We're not affiliated with Takara Bio Inc, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "T" | Takara Bio Inc-related inventors


 new patent  Lateral flow assays for non-diagnostic analytes

Methods of determining whether a non-diagnostic analyte is present in a non-diagnostic sample are provided. Aspects of the methods include applying a non-diagnostic sample to a sample receiving region of a lateral flow assay device and reading a detection region to determine whether a non-diagnostic analyte is present in the non-diagnostic sample. ... Takara Bio Inc

High-sensitivity method for detecting target nucleic acid

Provided are: a method with which it is possible to suppress nucleic-acid amplification of non-target nucleic acids and to selectively nucleic-acid amplify a target nucleic acid in a sample in which a large amount of non-target nucleic acids and a rare target nucleic acid are present in mixture; a method for detecting at high sensitivity rare mutant genes, the method combining this nucleic-acid amplification method and a specific real-time method for detecting the target nucleic acid; and a composition and kit for this method.. . ... Takara Bio Inc

Thermo-controllable high-density chips for multiplex analyses

The present invention provides miniaturized instruments for conducting chemical reactions where control of the reaction temperature is desired or required. Specifically, this invention provides chips and optical systems for performing and monitoring temperature-dependent chemical reactions. ... Takara Bio Inc

Thermo-controllable high-density chips for multiplex analyses

The present invention provides miniaturized instruments for conducting chemical reactions where control of the reaction temperature is desired or required. Specifically, this invention provides chips and optical systems for performing and monitoring temperature-dependent chemical reactions. ... Takara Bio Inc

Chimeric antigen receptors

Disclosed herein are chimeric antigen receptors (cars) comprising an intracellular segment comprising an interleukin receptor chain, a jak-binding motif, a signal transducer and activator of transcription (stat) 5 association motif and/or a cd3ζ intracellular signaling domain comprising an exogenous stat3 association motif, as well as cells and 5 compositions comprising said cars and uses thereof.. . ... Takara Bio Inc

Amplification and analysis of whole genome and whole transcriptome libraries generated by a dna polymerization process

The present invention regards a variety of methods and compositions for whole genome amplification and whole transcriptome amplification. In a particular aspect of the present invention, there is a method of amplifying a genome comprising a library generation step followed by a library amplification step. ... Takara Bio Inc

Coupling adaptors to a target nucleic acid

Methods of coupling adaptors to a target nucleic acid include coupling a first adaptor to a first end of the target nucleic acid to form a coupled first adaptor. A portion of a second adaptor is hybridized to a portion of the coupled first adaptor to form a hybridized second adaptor having a single-stranded 3′-end. ... Takara Bio Inc

Efficient induction of definitive endoderm from pluripotent stem cells

The present invention relates to a method to differentiate pluripotent stem cells to a primitive streak cell population, in a stepwise manner for further maturation to definitive endoderm.. . ... Takara Bio Inc

Spin columns comprising poly(acid) membrane separation matrices, and methods of making and using the same

Spin columns that include a poly(acid) membrane separation matrix are provided. Also provided are kits that include the subject devices, as well as methods of using the devices, e.g., in sample preparation (such as protein purification) protocols.. ... Takara Bio Inc

Methods of producing and using single-stranded deoxyribonucleic acids and compositions for use in practicing the same

Methods of producing single-stranded deoxyribonucleic acids (ssdnas) are provided. Aspects of the methods include generating a double stranded deoxyribonucleic acid (dsdna) and then selectively degrading one strand of the dsdna to produce a ssdna. ... Takara Bio Inc

Compositions and methods for processing and amplification of dna, including using multiple enzymes in a single reaction

The present invention concerns preparation of dna molecules, such as a library, using a stem-loop oligonucleotide. In particular embodiments, the invention employs a single reaction mixture and conditions. ... Takara Bio Inc

Methods for adding adapters to nucleic acids and compositions for practicing the same

Provided are methods of adding adapters to nucleic acids. The methods include combining in a reaction mixture a template nucleic acid, a template switch oligonucleotide, a polymerase, and dntps. ... Takara Bio Inc

Single cell capture with capture chips

The present invention provides methods, systems, assemblies, and articles for capturing single cells with a capture chip. In certain embodiments, the capture chip comprises a substrate comprising a plurality of cell-sized dimples or wells that each allow a single cell to be captured from a cell suspension. ... Takara Bio Inc

Method for improving nucleic acid synthesis reaction

Provided are the following: a method, for improving reactivity of an acid synthesis reaction, comprising a step for adding an ω-amino acid to a reaction solution; a composition, for a nucleic acid synthesis reaction, comprising dna polymerase, reaction buffer, at least one primer, at least one deoxyribonucleoside triphosphate, and an ω-amino acid; and a reaction buffer, for a nucleic acid synthesis reaction, comprising an ω-amino acid.. . ... Takara Bio Inc

07/13/17 / #20170198285

Methods for adding adapters to nucleic acids and compositions for practicing the same

Provided are methods of adding adapters to nucleic acids. The methods include combining in a reaction mixture a template ribonucleic acid (rna), a template switch oligonucleotide including a 3′ hybridization domain and a sequencing platform adapter construct, a polymerase, and dntps. ... Takara Bio Inc

07/13/17 / #20170198284

Methods for adding adapters to nucleic acids and compositions for practicing the same

Provided are methods of adding adapters to nucleic acids. The methods include combining in a reaction mixture a template ribonucleic acid (rna), a template switch oligonucleotide including a 3′ hybridization domain and a sequencing platform adapter construct, a polymerase, and dntps. ... Takara Bio Inc

06/15/17 / #20170166871

Production method for non-enveloped virus particles

Provided are a production method for non-enveloped virus particles which is characterized in that a sample including non-envelopes virus particles is treated with peg in at least two concentrations; a kit used in said production method; non-enveloped virus particles produced using said production method; and a pharmaceutical composition having the non-envelopes virus particles as an active ingredient.. . ... Takara Bio Inc

05/11/17 / #20170130197

Protein enriched microvesicles and methods of making and using the same

Protein enriched micro-vesicles and methods of making and using the same are provided. Aspects of the methods include maintaining a cell having a membrane-associated protein comprising a first dimerization domain and a target protein having a second dimerization domain under conditions sufficient to produce a micro-vesicle from the cell, wherein the micro-vesicle includes the target protein. ... Takara Bio Inc

01/05/17 / #20170002327

Directed differentiation and maturation of pluripotent cells into hepatocyte like cells by modulation of wnt-signalling pathway

Provided are improved methods using glycogen synthase kinase 3 (gsk3) inhibitors by which endodermal cells, notable endodermal cells derived from human pluripotent stem cells (hps), such as but not limited to hips-cells and hes-cells may be differentiated into hepatocyte like cells. The specific modulation of wingless integration gene (wnt)-signalling pathway and use of gsk3 inhibitors achieve direct differentiation and maturation of hepatocytes derived from human pluripotent stem (hps) cells. ... Takara Bio Inc








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