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The Jackson Laboratory patents

Recent patent applications related to The Jackson Laboratory. The Jackson Laboratory is listed as an Agent/Assignee. Note: The Jackson Laboratory may have other listings under different names/spellings. We're not affiliated with The Jackson Laboratory, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "T" | The Jackson Laboratory-related inventors

Non-hla matched humanized nsg mouse model with patient-derived xenograft

The invention described herein provides non-hla matched humanized mouse model (e.g., nsg mouse model) with patient-derived xenograft (pdx), as well as methods of making and using the same.. . ... The Jackson Laboratory

Isolation of non-embryonic stem cells and uses thereof

The invention described herein relates to methods of isolating non-embryonic stem cell, e.g., adult stem cell, from a non-embryonic tissue, e.g., an adult tissue or organ. Non-embryonic stem cells (e.g., adult stem cells) thus isolated from the various tissues or organs can self-renew or propagate indefinitely in vitro, are multipotent and can differentiate into the various differentiated cell types normally found within the tissue or organ from which the stem cells are isolated. ... The Jackson Laboratory

Three-component crispr/cas complex system and uses thereof

. . The invention described herein provides compositions and reagents for assembling a tripartite complex at a specific location of a target dna. The invention also provides methods for using the complex to, for example, label a specific genomic locus, to regulate the expression of a target gene, or to create a gene regulatory network.. ... The Jackson Laboratory

Pressure sensors for small-scale applications and related methods

Certain pressure sensor devices are much smaller than prior art devices, yet are at least as sensitive as the prior art devices. A capacitive pressure sensor can include a flexible substrate that permits bending of a pressure sensing region without significantly affecting operation thereof. ... The Jackson Laboratory

Compositions and methods relating to the treatment of cancer, autoimmune disease, and neurodegenerative disease

Described herein are methods and compositions relating to the treatment of e.g., cancer, autoimmune disease, immune deficiency, and/or neurodegenerative disease. In some embodiments, the methods of treatment relate to administering a compound as described herein. ... The Jackson Laboratory

Method and apparatus for preventing neurodegeneration

A method for treating, preventing and/or reducing neurodegeneration in subjects with neurodegenerative disease, such as those neurodegenerative diseases that affect the eye, including glaucoma, using radiation, such as gamma radiation or x-ray radiation, either alone or together with a bone marrow transfer treatment. The method includes irradiating a targeted area of an animal, such as the eye region, with radiation, either alone or followed by injection with t-cell depleted bone marrow cells. ... The Jackson Laboratory

Methods for identifying compounds that alter the activity of irhom polypeptides and use thereof

Methods for identifying a compound that modulates activity of an irhom polypeptide according to aspects of the present invention are described herein which include contacting a cell expressing an irhom polypeptide with a test compound; and determining the effect of the compound on activity of the irhom polypeptide. Detection of a decrease in proteolytic activity of the irhom polypeptide indicates that the compound is capable of one or more of: reducing tumor growth, reducing tumor progression, treatment of cancer and promoting hair growth in a subject, and detecting an increase in proteolytic activity of the irhom polypeptide indicates that the compound is capable of accelerating wound healing in a subject.. ... The Jackson Laboratory

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This listing is an abstract for educational and research purposes is only meant as a recent sample of applications filed, not a comprehensive history. is not affiliated or associated with The Jackson Laboratory in any way and there may be associated servicemarks. This data is also published to the public by the USPTO and available for free on their website. Note that there may be alternative spellings for The Jackson Laboratory with additional patents listed. Browse our Agent directory for other possible listings. Page by