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University Of South Carolina patents


Recent patent applications related to University Of South Carolina. University Of South Carolina is listed as an Agent/Assignee. Note: University Of South Carolina may have other listings under different names/spellings. We're not affiliated with University Of South Carolina, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "U" | University Of South Carolina-related inventors


 new patent  Biomimetic scaffolds including devitalized cells

Biomimetic scaffolds are described that incorporate devitalized cells that can function as a depot for the release of cell and tissue supporting factors. Methods for forming the biomimetic scaffolds are also described. ... University Of South Carolina

Micro-rna-155 enhances the efficacy of dendritic cell vaccine for cancer

Engineered dendritic cell vaccines, and methods of forming and applying same, that may be used as effective immunotherapies for cancers.. . ... University Of South Carolina

Double mesa large area alingabn led design for deep uv and other applications

Methods are provided for forming alingabn material. The method can include growing an alingabn layer on a substrate; removing a portion of the alingabn layer from the substrate to define a plurality of alingabn islands on the substrate; and growing a highly doped-alingabn layer on each of the alingabn islands.. ... University Of South Carolina

Etchant for use in rapid formation of robust porous polymers

A trifluoroacetic acid-based etchant is described that can remove a sacrificial component of a multi-component polymer, e.g., a self-assembled block copolymer. The etchant can operate at a high etch rate and with excellent selectivity. ... University Of South Carolina

Mocvd system injector for fast growth of alingabn material

A conical supply tube is provided, along with deposition systems using such a tube and methods of its use. The conical supply tube includes a conical head formed from a hollow structure defining a having a fitting end and an opposite, shower end, with the fitting end has an initial diameter that is less than a diameter at the shower end. ... University Of South Carolina

Cysteine-modifying substrate analogue inhibitors of ribose 5-phosphate isomerase for parasitic diseases, along with methods of their formation and use

Compounds are generally provided, along with pharmaceutical compositions including such compounds. Methods are also generally provided for inhibiting ribose 5-phosphate isomerase in a human, such as via administering to the human the pharmaceutical composition that includes such a compound. ... University Of South Carolina

Solid state electrolyte and electrochemical cell including the electrolyte

Solid state lithium ion conducting electrochemical cells and methods for forming the cells are described. The electrochemical cells include a composite solid state lithium ion conducting electrolyte separating porous metal supported electrodes. ... University Of South Carolina

Mixed anion cesium rare earth silicates

Scintillating compounds, methods of synthesizing scintillating compounds, and applications of scintillating compounds are disclosed. The scintillating compounds can include cesium rare earth silicates. ... University Of South Carolina

Preparation of maleate and maleimide monomers and polymeric materials from triglycerides

Monomer compounds and methods of synthesizing monomer compounds are disclosed. The monomer compounds can include maleate and maleimide monomers having fatty acid moieties. ... University Of South Carolina

Flange connectors for double tee beams

A connector for joining concrete structures such as double tee beams to one another. The connector includes a curved bolt that is formed with a shape memory alloy. ... University Of South Carolina

Method for detecting treated wood

The present disclosure is directed to a method for detecting whether a wood has been treated with a metal. The method comprises a step of applying a solution containing a color change agent and an antioxidant to the wood. ... University Of South Carolina

Direct synthesis of hydrocarbons from co-electrolysis solid oxide cell

A hydrocarbon generation system that combines a solid oxide electrolysis cell (soec) and a fischer-tropsch unit in a single microtubular reactor is described. This system can directly synthesize hydrocarbons from carbon dioxide and water. ... University Of South Carolina

Ultrasound barrier devices and methods related thereto

In one aspect, the present subject matter is directed to a barrier device. The barrier device has a generally flat base with a width and a length. ... University Of South Carolina

Fabrication method for micro-tubular solid oxide cells

A method for forming tubular solid oxide cells is described. The methods include co-extrusion of an electrode precursor and a sacrificial material to form a multi-layered precursor followed by phase inversion and sintering to remove the sacrificial layer and form an electrode substrate for use in a tubular solid oxide cell. ... University Of South Carolina

02/15/18 / #20180045688

Wireless damage assessment during manufacturing

A non-intrusive monitoring method and system for the detection and potential assessment of damage that may occur during a manufacturing process is described. Potential damage events such as impact events can be detected by one or more sensors located on a workpiece or on a machine utilized in the manufacturing process. ... University Of South Carolina

02/15/18 / #20180044816

Method of growing high quality, thick sic epitaxial films by eliminating silicon gas phase nucleation and suppressing parasitic deposition

Methods for forming an epilayer on a surface of a substrate are generally provided. For example, a substrate can be positioned within a hot wall cvd chamber (e.g., onto a susceptor within the cvd chamber). ... University Of South Carolina

02/15/18 / #20180044237

High strength reduced elastic modulus concrete

Concrete that exhibits increased flexibility (i.e., low modulus of elasticity) and high compressive strength is described. High aspect ratio structures as may be formed of the concrete are described. ... University Of South Carolina

02/08/18 / #20180037687

Polymer/copper combination for targeted cancer therapy

Polymer/copper combinations that can selectively target and kill cancer cells are described. Materials can include the reaction product of a biocompatible hydrophilic polymer and pyridine-2-thiol containing monomer. ... University Of South Carolina

01/04/18 / #20180006548

Bypass switch for high voltage dc systems

Many dc applications switching converter modules are multilevel, series connected converters. If an individual converter cell fails, it is desirable to be able to bypass the failed cell, in order to continue operating the rest of the converter. ... University Of South Carolina

12/28/17 / #20170369995

Mocvd system for growth of iii-nitride and other semiconductors

An mocvd system for growing a semiconductor layer on a substrate is provided. The mocvd system includes an mocvd growth chamber defined by a jacket having an interior surface and an exterior surface; a water flow chamber surrounding an exterior surface of the jacket of the mocvd growth chamber; an electronic control system, wherein the electronic control system facilitates pulsed growth of the semiconductor layer; a supply tube comprising a head formed from a hollow structure defining a fitting end and an opposite, shower end, wherein the fitting end has an initial diameter that is less than a diameter at the shower end; and a susceptor configured to hold the substrate and facing the shower end of the supply tube, wherein the mocvd system operates at a temperature greater than or equal to 1500° c.. ... University Of South Carolina

12/28/17 / #20170369886

Inhibin as targetable regulators of angiogenesis

Contact of endothelial cells with inhibitors of inhibin and/or the alpha subunit of inhibin can be utilized to modify the activity of endothelial cell expression products including smad 1/5. Methods can also include inhibiting alk1 and/or endoglin as components of inhibin-activated pathway of smad 1/5 signaling. ... University Of South Carolina

12/28/17 / #20170367974

Polymer implants for treatment of metabolic disorders

Implantable devices including a biocompatible matrix configured for long term location in adipose tissue and a biologically active agent that can be carried by the matrix and delivered to the adipose tissue following implant therein. The biologically active agent can include a modulator or a precursor thereof that can directly or indirectly modify the gene expression of adipose cells, e.g., adipocytes, and thereby modify the presence or quantity of one or more expression products of the adipose tissue that may act locally on distant from the implant site in an endocrine fashion. ... University Of South Carolina

12/21/17 / #20170363689

Accelerated testing protocols for solid oxide fuel cell cathode materials

Accelerated testing protocols that can be utilized for determining and projecting the durability of sofc cathodes are described. The accelerated testing protocols can be carried out under simulated operation conditions so as to provide in a matter of a few hundred hours data that can correlate to the condition of the cathode following operation of the cell over the course of a typical operation life span of several thousand hours. ... University Of South Carolina

12/07/17 / #20170348322

Bk channels as non-genomic estrogen targets for overactive bladder

Using bk channels as non-genomic estrogen targets in order to alleviate overactive bladder.. . ... University Of South Carolina

11/30/17 / #20170345325

Automated remote learning device and system for using same

A distance learning device for providing laboratory instruction via two-way interaction with a student at a remote location and system for using same.. . ... University Of South Carolina

11/23/17 / #20170335112

Tunable nanomaterials by templating from kinetically trapped polymer micelles

Products derived from and methods of micelle tem plating that allow for orthogonal control over structural features.. . ... University Of South Carolina

10/26/17 / #20170304220

Xanthohumol in antiarrythmic applications

Methods for modulating ca2+ signaling in cardiac myocytes by use of xanthohumol are described. Xanthohumol can suppress ca2+ signaling by suppressing spontaneous activity of the ryr2 receptor. ... University Of South Carolina

10/12/17 / #20170292479

Methodology and system for reforming liquid fuel

An on the fly fuel reformer device to produce variations in the autoignition and burning rate properties of a fuel by appropriate processing of some or all of a single fuel supply in its liquid form. The system includes a non-thermal plasma generator and/or a uv radiation source in contact with a fuel line so as to contact a multi-phase fuel in the line and dynamically modify the fuel to exhibit desired autoignition characteristics and burn rate such that the engine can operate with increased efficiency and lower emissions. ... University Of South Carolina

10/12/17 / #20170292197

Carbon gasification assisted solid oxide electrolysis cell

A syngas generation system that combines a solid oxide electrolysis cell (soec) and a carbon gasification unit is described. On the cathode side of the soec, co2 and h2o are electrochemically converted to syngas. ... University Of South Carolina

10/05/17 / #20170290137

Suppression of self pulsing dc driven nonthermal microplasma discharge to operate in a steady dc mode

. . The current disclosure relates to a suppressor circuit configuration for extending the stable region of operation of a dc driven micro plasma discharge at atmospheric and higher pressures.. . ... University Of South Carolina

09/28/17 / #20170275595

Bionanomaterials and their synthesis

The use of biomaterials, such as viruses and virus-like particles, to form nanostructures is generally disclosed. For instance, rod-like viruses can be used to form composite nanofibers that are fixed together in a head-to-tail assembly by a polymer. ... University Of South Carolina

09/21/17 / #20170266131

Modulation of macrophage phenotype by emodin

Methods and materials that can be used to regulate macrophage activation are described. Methods can utilize emodin to bi-directionally modulate macrophage activation and return macrophage phenotype to a homeostatic center (e.g., between m1 and m2 phenotypes) in various environmental settings. ... University Of South Carolina

09/14/17 / #20170258793

Method for treating prostate cancer

The invention provides a method for treating prostate cancer in a subject comprising administering to the subject an effective amount of a selective inhibitor of one or more of cdk8 and cdk19. In some embodiments the inhibitor inhibits cdk19. ... University Of South Carolina

09/07/17 / #20170253903

Quantitative acoustic contrast tomography for studying fungal growth and toxicity

Methods for ultrasonically imaging a heterogeneous 3d-cell population without physically probing are provided. The method can comprises: pulsing ultrasound waves having a wave frequency of about 10 mhz to about 2 ghz through a lens rod, wherein the lens rod focuses the ultrasound waves onto the cell population via a concave lens-head (e.g., comprising sapphire), and wherein the cell population is positioned on the reflective surface such that the ultrasound waves are reflected back to the lens-head; receiving the reflected waves through the lens head and the lens rod at a signal receiver; scanning the lens-head across multiple points in the x,y plane; and at each point in the x,y plane, moving the lens-head in a z-direction such that a signal is received at multiple intervals in the z-direction for each point in the x,y plane.. ... University Of South Carolina

08/31/17 / #20170247763

Leukocyte micrornas for use in diagnosis and treatment of endometriosis

Methods for diagnosis and treatment of endornetriosis are described. Methods utilize the recognition that leukocyte mirnas can be dramatically dysregulated subjects suffering from endometriosis. ... University Of South Carolina

08/31/17 / #20170247481

Separation of oil-water mixtures using nanotechnology

Methods for making a plurality of nanoparticles are provided. The method may include flowing a first component of the core into a reaction chamber; flowing a polymeric material into the reaction chamber; and flowing a second component of the core into the reaction chamber such that the first component reacts with the second component to form a core. ... University Of South Carolina

08/31/17 / #20170246321

Edible plants producing bioengineered micro-rna for gene regulation upon ingestion

Methods and materials providing a route for the use of transgenic plants as bio-factories to produce therapeutic mirnas are described. The plants can be ingestible and can be used to deliver to a subject in need thereof a therapeutic mirna by ingestion of the bioengineered plant tissue that carries an exogenous genetic sequence for the therapeutic mirna. ... University Of South Carolina

08/03/17 / #20170219532

Guided wave phased array beamforming

Systems and methods for evaluating an anisotropic composite material are provided. In one example implementation, a system includes a guided wave source configured to provide one or more guided waves to the anisotropic composite material. ... University Of South Carolina

08/03/17 / #20170218018

Cyclin based inhibitors of cdk2 and cdk4

Structural and functional analysis of peptide inhibitor binding to the cyclin d and cyclin a groove has been investigated and used to design peptides that provide the basis for structure-activity relationships, have improved binding and have potential for development as chemical biology probes, as potential diagnostics and as therapeutics in the treatment of proliferative diseases including cancer and inflammation.. . ... University Of South Carolina

07/27/17 / #20170211074

Mirna-489 in treatment of breast cancer

Breast cancer treatment methods and materials incorporating microrna-489 are described. The methods and materials have been developed from identification of a double-negative feedback loop between mir-489 and the her2-shp2-mapk signaling axis. ... University Of South Carolina

07/27/17 / #20170209559

Polymer-protein core-shell particles as effective vaccine delivery vehicles and treatments methods using the same

A polymer-protein core-shell nanoparticle is generally provided. In one embodiment, the polymer-protein core-shell nanoparticle includes a pyridinyl group grafted polymer assembled with a protein or a glycoprotein based antigen to form a core-shell particle. ... University Of South Carolina

07/13/17 / #20170196868

Methods and compositions for treatment of her-positive cancers

Cancers that overexpress tyrosine kinase receptors of her family are treated with drugs acting on these receptors. Although her-targeting drugs have revolutionized the treatment of her-positive cancers, high rates of primary and treatment-emergent resistance limit their clinical utility. ... University Of South Carolina

06/15/17 / #20170168021

Structural health monitoring method and system

Disclosed are composite structure health monitoring (shm) systems that incorporate aspects of both a passive shm system and an active shm system. Systems provide a route for continuous monitoring to recognize potentially damaging events as well as to determine the location and intensity of damage in those instances in which the event does cause damage to the structure. ... University Of South Carolina

06/15/17 / #20170166676

Initiator for surface-based polymerization and use thereof

Disclosed are polymerization initiators as may be utilized for addition of polymers to a substrate surface. The initiators are azo-based initiators that include multi-functionality through addition of multiple anchoring agents to an inner azo group. ... University Of South Carolina

05/04/17 / #20170122729

Optical displacement sensing system utilizing edge diffraction

Methods are provided for determining the position of a substrate. The edge diffraction model suitable for the proposed measurement apparatus was mathematically derived, and the effect of the parameters associated with the edge diffraction was investigated. ... University Of South Carolina

04/20/17 / #20170106076

Transmission blocking vaccines for mosquito-borne flaviviruses

. . Disclosed are transmission blocking vaccines for prevention or spread of one or more flaviviruses, and in particular, for prevention or spread of dengue virus. Vaccines can incorporate a polypeptide or a recombinant virus encoding a polypeptide that is non-homologous to human proteins and that is involved in flavivirus infection in a mosquito. ... University Of South Carolina

04/06/17 / #20170095558

Preparations of poly(lactic-co-glycolic acid)/polydopamine core/shell hybrid nanoparitcle for photothermal applications

Described is a biodegradable and biocompatible hybrid nanoparticle for use in photothermal applications. The hybrid nanoparticle includes a poly(lactide-co-glycolic acid) core and a polydopamine shell. ... University Of South Carolina

03/23/17 / #20170080096

Anion-paired cationic metallocene-containing compounds and polymers as antimicrobial agents

Anion-paired metallocene-containing compounds are generally provided, along with methods of making the same. In one embodiment, the anion-paired metallocene-containing compound includes a cationic metallocene moiety covalently connected to an organic functional group, and an anion paired to the cationic metallocene moiety. ... University Of South Carolina

03/16/17 / #20170071925

Ciclopirox for use in modulation of glucose homeostasis

Modulation of glucose homeostasis by administration of ciclopirox (6-cyclohexyl-1-hydroxy-4-methylpyridin-2(1h)-one) is described. Methods can be utilized in treatment of conditions that involve loss of glucose homeostasis, such as diabetes, and in one particular embodiment type ii diabetes. ... University Of South Carolina

02/23/17 / #20170050150

Tio2 nanofiltration membranes prepared by molecular layer deposition for water purification

Methods are provided for preparing tio2 nanofiltration membranes for water purification are provided. The method can include supplying a titanium precursor gas into a reaction chamber, where the titanium precursor gas reacts with a base support of an anodic aluminum oxide, and the base support of an anodic aluminum oxide has a surface defining a plurality of pores therein. ... University Of South Carolina

02/23/17 / #20170049726

Metformin in treatment of neuroblastoma

Use of metformin in inhibition of growth and/or viability of human neuroblastoma cells is described. Use of metformin in inhibition of growth and/or viability of neuroblastoma cancer stem cells is also described. ... University Of South Carolina

01/26/17 / #20170022067

Synthesis and crystal structure of iron zeolitic frameworks

Iron-based crystal structures including feo4 tetrahedrally coordinated in three dimensions in a framework analogous to a zeolite. The structures having the general formula ayb8fe12o24(o/oh)6.xh2o in which a is na, k, cs, rb or a combination thereof and b is an alkaline earth element or a combination of alkaline earth elements.. ... University Of South Carolina








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