Real Time Touch



new TOP 200 Companies filing patents this week

new Companies with the Most Patent Filings (2010+)




Real Time Touch

University Of Utah Research Foundation patents


Recent patent applications related to University Of Utah Research Foundation. University Of Utah Research Foundation is listed as an Agent/Assignee. Note: University Of Utah Research Foundation may have other listings under different names/spellings. We're not affiliated with University Of Utah Research Foundation, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "U" | University Of Utah Research Foundation-related inventors


Tracheal intubation system including a laryngoscope

A tracheal intubation system including a laryngoscope is disclosed. An endotracheal tube exchange system is also disclosed. ... University Of Utah Research Foundation

Adhesive complex coacervates and methods of making and using thereof

Described herein is the synthesis of adhesive complex coacervates and their use thereof. The adhesive complex coacervates are composed of a mixture of one or more polycations and one or more polyanions. ... University Of Utah Research Foundation

Combination of creatine, an omega-3 fatty acid, and citicoline

In one aspect, the invention relates to compositions comprising at least one creatine or creatine analog, at least one omega-3 fatty acid, and citicoline analogs. Also disclosed are methods of using same, alone or in combination with other agents, to treat depression disorders and associated maladies. ... University Of Utah Research Foundation

Therapeutic compositions

A therapeutic composition can include an amount of amniotic fluid having a therapeutically effective amount of at least one protein, hyaluronic acid, or both. The therapeutic composition can be substantially free of lanugo, vernix, and cells harvested with the amniotic fluid.. ... University Of Utah Research Foundation

Intraocular drug delivery device and associated methods

An intraocular active agent delivery device can include an active agent homogenously combined with a biodegradable active agent matrix such that the entire delivery device is homogenous. The homogenous delivery device can have a shape and size to fit within a lens capsule or ciliary sulcus of an eye and provide a therapeutically effective amount of the active agent to the eye. ... University Of Utah Research Foundation

Systems and methods for administering treatment of atrial fibrillation

Methods and systems are described for treatment of atrial fibrillation. Certain embodiments provide methods of assessing a risk of thromboembolic stroke in a patient. ... University Of Utah Research Foundation

Ultra-low power digital chemical analyzers

A zero-power digital chemical analyzer can include a chemically-selective percolation switch. The chemically selected percolation switch can include a positive electrode and a negative electrode separated from the positive electrode by a gap. ... University Of Utah Research Foundation

Systems and methods for managing power generation and storage resources

An operating configuration for a power system during a particular time period may be derived from a net load forecast for the power system during the particular time period. The operating configuration may be based on inter-temporal and/or continuous-time characteristics of the net load forecast. ... University Of Utah Research Foundation

Hpma-drug conjugates for the treatment of acute myeloid leukemia

Disclosed are methods are of treating acute myeloid leukemia (aml) comprising administering an effective amount of a first aml therapeutic and an effective amount of a second aml therapeutic. Also disclosed are methods of treating aml comprising administering an effective amount of a first aml therapeutic conjugated to n-(2-hydroxypropyl)methacrylamide (hpma) copolymer. ... University Of Utah Research Foundation

Light-weight bridge support systems and methods of use

A bridge support system includes a support embankment formed from at least one light-weight material. The support embankment is arranged to support and be positioned under a footing of a bridge structure. ... University Of Utah Research Foundation

Macromolecular delivery systems for non-invasive imaging, evaluation and treatment of arthritis and other inflammatory diseases

This invention relates to biotechnology, more particularly, to water-soluble polymeric delivery systems for the imaging, evaluation and/or treatment of rheumatoid arthritis and other inflammatory diseases. Using modern mr imaging techniques, the specific accumulation of macromolecules in arthritic joints in adjuvant-induced arthritis in rats is demonstrated. ... University Of Utah Research Foundation

Sensor compounds and associated methods and devices

Methods of detecting a non-explosive analyte can include exposing a sensor compound to a non-explosive analyte and displaying a change in the sensor compound upon exposure of the sensor compound to the non-explosive analyte. A variety of sensor compounds for detecting a target analyte, including both explosive and non-explosive analytes, is also described. ... University Of Utah Research Foundation

Methods for fast nucleic acid amplification

Methods, devices, and kits are provided for performing pcr in <20 seconds per cycle, with improved efficiency and yield.. . ... University Of Utah Research Foundation

Methods of predicting the development of complement-mediated disease

Described herein are methods for determining a caucasian subject's susceptibility to having or developing a complement-mediated disease comprising determining in the caucasian subject the identity of one or more haplotypes, wherein the presence of one or more of the haplotypes indicates the subject's susceptibility for having or developing a complement-mediated disease.. . ... University Of Utah Research Foundation

06/07/18 / #20180155696

Methods and compositions relating to viral latency

Disclosed are compositions and methods that relate generally to viruses, and more particularly to the agents and their identification and use of anti-hiv agents which cause latently infected cells to reactivate.. . ... University Of Utah Research Foundation

06/07/18 / #20180153714

Modular prosthetic abutment system

An abutment system for operatively coupling an implant stem to an exo-prosthesis. The abutment system includes a plurality of interlocking sleeve elements that are operatively coupled to an implant stem positioned within a prepared site of a selected bone. ... University Of Utah Research Foundation

05/31/18 / #20180147316

Simple coacervates and methods of use thereof

Described herein is the synthesis of adhesive from simple adhesive coacervates and their uses thereof. The adhesives are composed of (a) a polyanion in the absence of a polycation, wherein the polyanion comprises at least one crosslinking group capable of covalently crosslinking with itself, and (b) a sufficient amount of a complimentary multivalent cation or multivalent anion to produce the simple coacervate. ... University Of Utah Research Foundation

05/31/18 / #20180147286

Bone fracture repair by targeting of agents that promote bone healing

Aspects of the present disclosure generally relate to compounds for targeting and healing bone fractures. Some of these compounds include a negatively charged oligopeptide comprising an acidic oligopeptide, a linker, which may be hydrolyzable or may be a substrate for the protease cathepsin k, and at least one molecule that promotes bone healing. ... University Of Utah Research Foundation

05/24/18 / #20180141995

Compositions and methods for the intracellular disruption of vegf and vegfr-2 by intraceptors

The present invention provides an intraceptor that interacts with and decreases activity of with vegf and/or a vegfr for the treatment of angiogenesis-related conditions. The present invention further provides pharmaceutical compositions, and methods of use thereof for the treatment and prevention of an angiogenesis-related condition using said intraceptors. ... University Of Utah Research Foundation

05/17/18 / #20180134729

Methods and compositions of substituted 5h-[1,2,5] oxadiazolo [3',4':5,6] pyrazino[2,3-b] indole analogs as inhibitors of beta-catenin/t-cell factor protein-protein interactions

In one aspect, the invention relates to substituted 5h-[1,2,5]oxadiazolo [3′,4′:5,6]pyrazino[2,3-b]indole analogues, derivatives thereof, and related compound; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and a methods of treating disorders, e.g., various tumors and cancers, associated with a β-catenin/t-cell factor interaction dysfunction using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.. ... University Of Utah Research Foundation

05/17/18 / #20180134719

Substituted n-(3-(pyrimidin-4-yl)phenyl)acrylamide analogs as tyrosine receptor kinase btk inhibitors

In one aspect, the invention relates to substituted n-(3-(pyrimidin-4-yl)phenyl)acrylamide analogs, derivatives thereof, and related compounds, which are useful as inhibitors of the btk kinase; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of using the compounds and compositions to treat disorders associated with dysfunction of the btk kinase. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.. ... University Of Utah Research Foundation

05/17/18 / #20180133374

Implantable devices for bone or joint defects

In one aspect, the invention provides an implantable device comprising a uniform mixture of components including degradable polymer, inorganic bone particulate either natural or synthetic, a drug, and a soluble microporagen. In some embodiments, the uniform mixture further includes a soluble polymer macroporagen. ... University Of Utah Research Foundation

05/10/18 / #20180130936

High-performance terbium-based thermoelectric materials

A thermoelectric material, having a formula tbxm1y-xm2zow where m1 is one of ca, mg, sr, ba and ra, m2 is at least one of co, fe, ni, and mn, x ranges from 0.01 to 5; y is 1, 2, 3, or 5; z is 1, 2, 3, or 4; and w is 1, 2, 3, 4, 5, 7, 8, 9, or 14. The thermoelectric material is chemically stable within 5% for one year and is also non-toxic. ... University Of Utah Research Foundation

05/10/18 / #20180125922

Compositions and methods of use for (pro)renin receptor antagonists

Disclosed are methods of treating kidney disease, infectious or inflammatory diseases, acute kidney injury and hypertension by administering a (pro)renin receptor (prr) antagonist. In some instances the prr antagonist is a polypeptide. ... University Of Utah Research Foundation

05/10/18 / #20180125070

Compositions and methods comprising a biocidal polyamine

Compounds, compositions, and methods comprising a polyamine compound are described, which may be used to kill, disperse, treat, or reduce biofilms, or to inhibit or substantially prevent biofilm formation. In certain aspects, the present invention relates to compounds, compositions, and methods comprising polyamine compounds that have antimicrobial or dispersing activity against a variety of bacterial strains capable of forming biofilms.. ... University Of Utah Research Foundation

05/03/18 / #20180122507

Genetic alterations in ovarian cancer

According to various embodiments herein, methods for performing diagnosis and prognosis of ov have been provided. In embodiments, a method of determining an estimated outcome or predicting a clinical response to chemotherapy for a patient having ovarian serous cystadenocarcinoma (ov), comprises obtaining a biological sample from a patient diagnosed with ov, said sample comprising at least one of nucleic acids and proteins from the patient; detecting in said sample a value of an indicator of a differential expression; and calculating, by a processor, a weighted sum pattern based on the value of one or more of the indicators of differential expression; and estimating, by the processor and based on the weighted sum pattern, a predicted length of survival of the patient or a predicted clinical response to chemotherapy for the patient.. ... University Of Utah Research Foundation

04/19/18 / #20180104182

Intravaginal devices for controlled delivery of lubricants

The present technology provides intravaginal devices designed to deliver lubricants to the vagina for a sustained period of time. The intravaginal devices include a first segment comprising an outer surface and a lumen containing a lubricant, wherein the first segment is configured to deliver the contents of the lumen to the outer surface, and the first segment comprises a polymer selected from the group consisting of a hydrophilic, semi-permeable elastomer and a hydrophobic elastomer. ... University Of Utah Research Foundation

04/12/18 / #20180099070

Reinforced adhesive complex coacervates and methods of making and using thereof

Described herein is the synthesis of reinforced adhesive complex coacervates and their use thereof. The reinforced adhesive complex coacervates are composed of (a) at least one polycation, (b) at least one polyanion, and (c) a reinforcing component. ... University Of Utah Research Foundation

04/05/18 / #20180095300

Photonic modulator structures and methods of manufacture

Metamaterial optical modulators can include one or more optical inputs, one or more optical outputs, one or more control inputs and an arrangement of a plurality of elements. The plurality of elements can include one or more variable state elements. ... University Of Utah Research Foundation

04/05/18 / #20180093273

Thermal gradient plug flow microfluidic devices for extreme pcr

A microfluidic device can include a temperature regulator positioned to generate a temperature gradient across a thermally controlled portion of the microfluidic device from a high temperature region to a low temperature region. Additionally, the microfluidic device can include a bi-directional microfluidic serpentine pathway having a first terminus and a second terminus. ... University Of Utah Research Foundation

04/05/18 / #20180092873

Use of nitrated lipids for treatment of side effects of toxic medical therapies

Methods of treating the side effects of a toxic medical therapy using nitrated lipids are disclosed herein. In particular, the methods comprise the use of nitrated fatty acids or esters thereof to treat side effects, including organ system damage, caused by chemotherapy, radiotherapy, and the administration of other toxic agents.. ... University Of Utah Research Foundation

04/05/18 / #20180092866

Substituted n-([1,1'-biphenyl]-3-yl)-[1,1'-biphenyl]-3-carboxamide analogs as inhibitors for beta-catenin/b-cell lymphoma 9 interactions

In one aspect, the invention relates to substituted n-([1,1′-biphenyl]-3-yl)-[1,1′-biphenyl]-3-carboxamide analogues, derivatives thereof, and related compound; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating disorders, e.g., various tumors and cancers, associated with β-catenin/bcl9 protein-protein interaction dysfunction using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.. ... University Of Utah Research Foundation

03/29/18 / #20180087098

Methods for detecting rapidly processed introns to evaulate allelic expression

The invention is directed to methods for identifying one or more introns of a gene that are rapidly processed from a nascent rna molecule transcribed from the gene, which allows for the detection of allele-specific expression of a gene in a single cell.. . ... University Of Utah Research Foundation

03/22/18 / #20180080899

Fixed area electrode for electrochemical analysis of high temperature fluids

A method of making an electroanalytical measurement including providing a glass-fused working electrode that includes a tungsten rod and a glass coating fused to the rod to form a leak-proof seal, which defines a fixed working electrode area; inserting the electrode into a molten salt such that the fixed working electrode area is completely submerged and a portion of the glass coating is in contact with the molten salt; applying a potential to the molten salt; measuring current as a function of potential; and quantifying a concentration of an analyte.. . ... University Of Utah Research Foundation

03/01/18 / #20180057874

Multi-sequence capture system

Systems, devices, and methods for capturing single source-specific biological material from a multi-source aggregate of biological material are disclosed and discussed. A capture system is generated using reversible chain-blocking to make capture substrates having substrate-linked populations of capture molecules specific for molecules of interest. ... University Of Utah Research Foundation

02/22/18 / #20180052050

Imaging device with image dispersing to create a spatially coded image

An image capturing device (202) can include a sensor array (210), a lens (230) positioned at a first distance from an intermediate image (235), and apolychromat (220) positioned at a second distance from the lens (230). The polychromat (220) can diffract the intermediate image (235) according to a transform function (207) to produce a dispersed sensor image (215) onto the sensor array (210). ... University Of Utah Research Foundation

02/22/18 / #20180051980

Interferometry system and associated methods

Devices, systems, and methods for determining a distance between at least two points are disclosed and described, wherein interferometry technology is utilized to determine such distances.. . ... University Of Utah Research Foundation

02/22/18 / #20180049665

Methods and systems of evaluating axonal loss and demyelination

Disclosed are methods and systems for obtaining ultra-high b radial diffusion-weighted imaging signals from a selected portion of a nervous system of a subject and comparing at least two ultra-high b radial diffusion-weighted imaging signals for the selected portion of the nervous system of the subject. The comparison is indicative of changes in the integrity or intactness of a bundle of axons within the selected portion of the nervous system of the subject.. ... University Of Utah Research Foundation

02/08/18 / #20180036440

Methods for diagnosing and monitoring eosinophilic esophagitis

Disclosed are compositions and methods for diagnosing eosinophilic esophagitis in a subject. Also disclosed are methods for monitoring the course of eosinophilic esophagitis in a subject before, during, and after treatment. ... University Of Utah Research Foundation

02/01/18 / #20180031584

Methods of detecting analytes and diagnosing tuberculosis

A method for detecting lipoarabinomannan in a biological sample is described, including the step of contacting the biological sample with at least one acid selected from the group consisting of perchloric acid, trifluoroacetic acid, and sulfosalicylic acid. Methods for diagnosing diseases, including tuberculosis, and kits for the described methods are also presented.. ... University Of Utah Research Foundation

02/01/18 / #20180031467

Temperature profile for rock sample composition analysis

A method for analyzing the petroleum content of a rock sample includes at least three repetitions of heating a rock sample to a holding temperature, holding the rock sample at the holding temperature for a holding period, and collecting data about the rock sample during each holding period. The holding temperature for each subsequent holding period may be greater than or equal to a previous holding temperature. ... University Of Utah Research Foundation

01/25/18 / #20180021331

Hdac1,2 inhibitors and methods of using the same

Disclosed herein are methods for treating a cancer and a method for sensitizing a cancer to a chemotherapeutic agent. Each method administers an agent that selectively inhibits hdac1 and hdac2 to a subject in need thereof. ... University Of Utah Research Foundation

01/18/18 / #20180018858

Skin stretch feedback devices, systems, and methods

Embodiments of the present disclosure relate devices, systems, methods, and for displaying information about the direction and magnitude of position, movement, and/or resistive force experienced for an object. The present disclosure also provides a shear display device that can generate skin shear with one or more tactors. ... University Of Utah Research Foundation

01/11/18 / #20180010167

Organism identification panel

Methods and containers are provided for identifying a species, illustratively a bacterial species. Illustrative methods comprise amplifying various genes in the nucleic acid from the bacterial species in a single reaction mixture using pairs of outer first-stage primers designed to hybridize to generally conserved regions of the respective genes to generate a plurality of first-stage amplicons, dividing the reaction mixture into a plurality of second-stage reactions, each using a unique pair of second-stage primers, each pair of second-stage primers specific for a target bacterial species or subset of bacterial species, detecting which of the second-stage reactions amplified, and identifying the bacterial species based on second-stage amplification. ... University Of Utah Research Foundation

01/11/18 / #20180009851

Compositions and methods for peptide expression and purification using a type iii secretion system

Disclosed are compositions and methods for expressing and purifying a peptide of interest using a flagellar type iii secretion system. Disclosed are nucleic acid sequences that contain a flgm nucleic acid sequence, a cleavage site, and a nucleic acid sequence of interest. ... University Of Utah Research Foundation

01/04/18 / #20180000960

Dimeric collagen hybridizing peptides and methods of using

Disclosed are peptide conjugates comprising an active agent, a spacer moiety, and a dimeric collagen hybridizing peptide comprising a first and second collagen hybridizing peptide, a linker; and a branch point, wherein the first and second collagen hybridizing peptides comprise the sequence of at least (gxy)n, wherein g is glycine, wherein x and y are any amino acid, and wherein n is any number between 3 and 12. Also disclosed are methods of detecting denatured collagen in a sample comprising contacting a composition comprising any one of the disclosed peptide conjugates to a sample, wherein the active agent comprises a therapeutic agent, and detecting the presence or absence of binding of the peptide conjugate to denatured collagen, the presence of binding indicating the presence of denatured collagen in the sample. ... University Of Utah Research Foundation

12/28/17 / #20170368334

Spinal cord stimulation system

A method for optimizing the stimulation of the dorsal column of the spinal cord is disclosed. The method includes providing a stimulating electrode array and a frame element. ... University Of Utah Research Foundation

12/28/17 / #20170368196

Bi-functional allosteric protein-drug molecules for targeted therapy

Disclosed herein, is a bi-functional allosteric protein-drug molecule comprising a targeting moiety, one or more biological binding domains, and one or more therapeutic agents, wherein the therapeutic agent is allosterically bound to the biological binding domain. Also described herein, are methods of incorporating a bi-functional allosteric protein-drug molecule comprising a targeting moiety, one or more biological binding domains that captures the therapeutic agent without the formation of a chemical bond, and one or more therapeutic agents; physiologically acceptable compositions including them; and methods of administering the bi-functional allosteric protein-drug molecule to patients for the treatment of cancer.. ... University Of Utah Research Foundation

12/21/17 / #20170361307

Nanodiamond supported catalytic nanoparticles and associated methods

A catalytic nanoparticle can include a nanodiamond core, a thin-layer polymeric film applied to an outer surface of the nanodiamond core, and a catalyst immobilized at an outer surface of the thin-layer polymeric film. The nanoparticles can also be used in connection with a transducer to form a sensor. ... University Of Utah Research Foundation

12/21/17 / #20170361054

Medical gas delivery device

Medical gas delivery devices are provided. A garment or another object may include a hose assembly configured to couple the garment or the object to a medical gas source. ... University Of Utah Research Foundation

12/21/17 / #20170360784

Trizol-1-ol analogs anti-retroviral latency drugs

In one aspect, the invention relates to triazol-1-ol compounds, analogs thereof, compositions comprising same, and methods of using same, alone or in combination with other agents, to reactivate latent retroviruses, and more particularly to reactivate latent hiv-1. Such compounds, compositions, and methods can be used, for example, in connection with diagnosing and/or treating a retrovirus, and more specifically hiv-1. ... University Of Utah Research Foundation

12/14/17 / #20170356695

Climate control system and associated methods

A climate control system is described that can include a thermal battery (100) with a heating bed (110) and cooling bed (120) and a conditioned air manifold adapted to direct heat transfer fluid across at least one of the heating bed (110) and the cooling bed (120) to condition inlet air. A method of controlling climate in an enclosure can be provided by contemporaneously generating a heating effect and a cooling effect from a reversible thermo chemical reaction and selectively directing thermal flows from a reversible thermo chemical reaction to the enclosure.. ... University Of Utah Research Foundation

12/14/17 / #20170354756

Polyphosphate hydrogels and methods of making and using thereof

Described herein are hydrogels with improved mechanical properties. The hydrogels are composed of two polymer networks covalently crosslinked with one another. ... University Of Utah Research Foundation

12/07/17 / #20170352775

Methods for creating cadmium telluride (cdte) and related alloy film

A method of creating cadmium telluride films is presented. The method demonstrates heterogeneous nucleation of cdte directly on a substrate through sequential deposition of aqueous precursor solutions containing cadmium and telluride ions, respectively. ... University Of Utah Research Foundation

11/23/17 / #20170336378

Ultra-low power digital chemical analyzers

A zero-power digital chemical analyzer can include a chemically-selective percolation switch. The chemically selected percolation switch can include a positive electrode and a negative electrode separated from the positive electrode by a gap. ... University Of Utah Research Foundation

11/23/17 / #20170332940

Patient specific scan parameters for mri scanning

A method of optimizing scan parameters for lge-mri. At least one cardiac mri ti scout scan is performed by applying an inversion pulse every predetermined heartbeat of a patient. ... University Of Utah Research Foundation

11/16/17 / #20170329635

Systems and methods for distributed computing

A distributed computing manager provides access to computing resources of a plurality of separate computing systems. The distributed computing manager emulates the distributed computing resources as a unitary computing system comprising an emulated processor, i/o, memory, and so on. ... University Of Utah Research Foundation

11/16/17 / #20170327796

Induced pluripotent stem cell and method for producing the same

The disclosure provides an episome comprising oct4, klf4, sox2, cmyc, nanog, lin28, and nrsa2. Also disclosed is a method for producing an induced pluripotent stem (ips) cell. ... University Of Utah Research Foundation

11/09/17 / #20170323080

Disease therapy game technology

A video game in possession of and/or in the proximity of a patient. The patient computing system receives an indication that it is to begin a game, and executes the game using identified game parameters that are associated with the patient by a clinician as part of a disease therapy program. ... University Of Utah Research Foundation

11/09/17 / #20170322274

Multi-echo pseudo-golden angle stack of stars thermometry with high spatial and temporal resolution using k-space weighted image contrast

A method for producing an image of a subject using a magnetic resonance imaging (mri) system includes acquiring a series of echo signals by sampling k-space along radial lines that each pass through the center of k-space. Each projection of the radial lines is divided into multiple echoes and successive projections are spaced by a predetermined angular distance. ... University Of Utah Research Foundation

10/26/17 / #20170306288

Tissue sample processing system and associated methods

A tissue sample processing system and associated methods is disclosed and described. The tissue sample processing system (100) can include a microfluidic separating system (110). ... University Of Utah Research Foundation

10/26/17 / #20170304367

Methods of treating hypoxia-associated optical conditions with cartilage oligo matrix protein-angiopoietin 1 (comp-ang1)

Methods, compositions, and systems for treating ischemia-associated and other ocular conditions using cartilage oligo matrix protein-angiopoietin 1 (comp-ang1) are disclosed and described.. . ... University Of Utah Research Foundation

10/12/17 / #20170295327

Multi-spectral imaging with diffractive optics

. . A multi-spectral imaging (msi) device can include an imaging plane and a diffractive optic. The imaging plane can include at least two groups of pixels an array of pixels for sensing at least two spectral bands. ... University Of Utah Research Foundation

10/05/17 / #20170289215

Method and system for data streaming

A technology is disclosed and described for distributing data packets. An example method may include creating a network connection between a source node and a gatherer server. ... University Of Utah Research Foundation

10/05/17 / #20170283397

Substituted 1-h-indol-3-yl-benzamide and 1, 1'-biphenyl analogs as histone demethylase inhibitors

Substituted 1-h-indol-3-yl-benzamide and 1, 1′-biphenyl analogs derivatives thereof, and related compounds, which are useful as inhibitors of lysine-specific histone demethylase, including lsd1; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of using the compounds and compositions to treat disorders associated with dysfunction of the lsd1.. . ... University Of Utah Research Foundation

10/05/17 / #20170281941

Electronic nerve stimulation

A technology is described for an electronic nerve stimulation system. The electronic nerve stimulation system can include a stimulation device operable to generate a high-frequency alternating current. ... University Of Utah Research Foundation

10/05/17 / #20170281231

Uterine contraction device

The present disclosure describes a uterine contraction device which may be utilized to treat and/or prevent postpartum hemorrhaging. The uterine contraction device includes a catheter and a pressure seal adjustably coupled to the catheter. ... University Of Utah Research Foundation

09/28/17 / #20170273899

Intravaginal devices for controlled delivery of lubricants

The present technology provides intravaginal devices designed to deliver lubricants to the vagina for a sustained period of time. The intravaginal devices include a first segment comprising an outer surface and a lumen containing a lubricant, wherein the first segment is configured to deliver the contents of the lumen to the outer surface, and the first segment comprises a polymer selected from the group consisting of a hydrophilic, semi-permeable elastomer and a hydrophobic elastomer. ... University Of Utah Research Foundation

09/21/17 / #20170268997

Chemical probes for hydrogen sulfide

Chemical probes and methods for detecting and/or quantifying hydrogen sulfide are disclosed. More particularly, this application discloses chemical probes and methods for their use for detecting and/or quantifying hydrogen sulfide in industrial and environmental samples and effluents, including samples of crude oil and sour water produced by petrochemical and other industrial processes.. ... University Of Utah Research Foundation

09/21/17 / #20170267729

Vaccine antigens that direct immunity to conserved epitopes

A method of identification and elimination of immunodominant epitopes to elicit a response to secondary epitopes, especially conserved structures, is described, and applied to influenza haemagglutinin (ha). Identification of the primary epitopes in (ha), and replacement of amino acids having high lodrps with corresponding low lodrps amino acids produces an ha molecule which induces antibody responses to conserved ha residues. ... University Of Utah Research Foundation

08/31/17 / #20170247418

Ebolavirus pre-hairpin intermediate mimics and methods of use

Ebolavirus is a highly lethal filovirus that causes hemorrhagic fever in humans and non-human primates. With no approved treatments or preventatives, the development of an anti-ebolavirus therapy to protect against natural infections and potential weaponization is an urgent unmet global health need. ... University Of Utah Research Foundation

08/24/17 / #20170244392

Relative timed clock gating cell

Technology is described for a relative timed clock gated cell. In one example, the relative timed clock gated cell includes a trigger latch and a data clock latch. ... University Of Utah Research Foundation

08/24/17 / #20170244042

Organic light-emitting apparatus

An organic light-emitting apparatus includes an organic light-emitting device and a magnetic field-applying member that applies a magnetic field to the organic light-emitting device. The organic light-emitting device includes a host and a dopant.. ... University Of Utah Research Foundation

08/24/17 / #20170241961

Micro circulatory gas chromatography system and method

A gas chromatography system can include a circulatory loop, a gas inlet positioned along the circulatory loop, a gas outlet positioned along the circulatory loop, a micro column positioned in line with the circulatory loop, and an in-line population sensor positioned in line with the circulatory loop. The in-line population sensor can be configured to detect changes in gas population. ... University Of Utah Research Foundation

08/24/17 / #20170239364

Methods and compositions related to inhibition of viral entry

Disclosed herein are compositions and methods for inhibiting viral entry.. . ... University Of Utah Research Foundation

08/24/17 / #20170239272

Intraocular drug delivery device and associated methods

An intraocular active agent delivery device can include an active agent homogenously combined with a biodegradable active agent matrix such that the entire delivery device is homogenous. The homogenous delivery device can have a shape and size to fit within a lens capsule or ciliary sulcus of an eye and provide a therapeutically effective amount of the active agent to the eye. ... University Of Utah Research Foundation

08/24/17 / #20170239212

Bryostatin analogs and use thereof as antiviral agents

Described herein are tricyclic macrolactones. The macrolactones have a high binding affinity for pkc. ... University Of Utah Research Foundation

08/17/17 / #20170233269

Water treatment device

A water treatment device (100) can include a chamber (104) having an inlet (108) to receive water contaminated with pathogens and an outlet (110) to dispense treated water. The water treatment device (100) can also include a catalytic element (130) disposed in the chamber (104) to deactivate the pathogens in the water via at least one of electrocatalytic activity and photocatalytic activity. ... University Of Utah Research Foundation

08/17/17 / #20170232081

Methods for treatment of and prophylaxis against inflammatory disorders

An isolated and purified peptide, neonatal net-inhibitory factor (nnif), is disclosed. Methods for treatment of and prophylaxis against inflammatory disorders are also disclosed, including methods of treatment of and prophylaxis against inflammatory disorders comprising administering net-inhibitory peptides (nips), which may be a nnif, a pharmaceutically acceptable salt of a nnif, a nnif analog, a pharmaceutically acceptable salt of a nnif analog, a nnif-related peptide (nnrp), including the nnrp, cancer-associated scm-recognition, immune defense suppression, and serine protease protection peptide (crispp), a pharmaceutically acceptable salt of a nnrp, a nnrp analog, or a pharmaceutically acceptable salt of a nnrp analog, to an individual.. ... University Of Utah Research Foundation

08/03/17 / #20170218375

Morpholinos, morpholino upregulating, and associated methods

Various methods and compositions relating to vascular endothelial growth factor receptor 2 (vegfr2) are provided. In one aspect, a method of increasing expression of the soluble form of vegfr2 (svegfr2) in a subject can include binding an antisense morpholino to an exon13-intron13 splicing site of vegfr2 mrna such that the vegfr2 mrna is spliced into a svegfr2 isoform.. ... University Of Utah Research Foundation

08/03/17 / #20170218363

Morpholino-mediated increase in soluble flt-1 expression results in decreased ocular and tumor neovascularization

Methods of inhibiting lymphangiogenesis and/or angiogenesis in a subject are provided. In one aspect, for example, a method of inhibiting angiogenesis in a subject can include binding an antisense morpholino to an mrna splicing site of vegfr1 selected from exon13_intron13 junction, intron13_exon14 junction, or a combination thereof. ... University Of Utah Research Foundation

07/27/17 / #20170209084

Diagnosis of affective disorders using magnetic resonance spectroscopy neuroimaging

A method for facilitating diagnosis of an affective disorder in a person can include (a) acquiring 1h spectroscopic data to obtain an indicator of total choline (tcho) and creatine (cr) in an area, e.g., the anterior cingulate cortex, of the person's brain; and (b) determining, by a processor and based on the indicator, at least one of (i) a likely diagnosis of bipolar disorder or major depressive disorder, or (ii) a probability of bipolar disorder or major depressive disorder, in the person.. . ... University Of Utah Research Foundation

07/06/17 / #20170189405

Arf6 inhibitors and methods of synthesis and use thereof

Disclosed herein are compounds and methods for inhibiting arf6. Pharmaceutical compositions and methods for treating a subject with an inhibitor of arf6 are also disclosed herein.. ... University Of Utah Research Foundation

06/29/17 / #20170182612

System and method for dispensing a minimum quantity of cutting fluid

Devices, systems, and methods are provided for controlling a quantity of cutting fluid dispensed for a cutting tool within a cnc or other machining system. The devices, systems, and methods may include controlling multiple fluids such that coolant, lubricant, or other fluids can be delivered at different locations, at different flow rates, have their flow rates changed independently, and/or have their flow rates changed dynamically during a machining operation. ... University Of Utah Research Foundation

06/22/17 / #20170175113

Methods for modulating ataxin 2 expression

Disclosed herein are methods for decreasing ataxin 2 mrna and protein expression. Such methods are useful to treat, prevent, or ameliorate ataxin 2 associated diseases, disorders, and conditions. ... University Of Utah Research Foundation

06/22/17 / #20170174750

Peptide inhibitors of bcr-abl oligomerization

In one aspect, the invention relates to peptides comprising the bcr-abl coiled-coil oligomerization domain and an alpha helix stabilizing moiety, mutant forms thereof, truncated forms thereof, derivatives thereof, and related peptides, which are useful as inhibitors of the bcr-abl chimeric protein; pharmaceutical compositions comprising the compounds; and methods of treating hyperproliferative disorders associated with bcr-abl using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.. ... University Of Utah Research Foundation

06/15/17 / #20170166966

Autism associated genetic markers

The present disclosure relates to the identification of a subject that is affected with, or predisposed to, autism or to one or more autism spectrum disorders (asd). The present disclosure includes methods related to the association of certain genetic markers with autism and/or asd. ... University Of Utah Research Foundation

06/15/17 / #20170165264

Combination of creatine, an omega-3 fatty acid, and citicoline

In one aspect, the invention relates to compositions comprising at least one creatine or creatine analog, at least one omega-3 fatty acid, and citicoline analogs. Also disclosed are methods of using same, alone or in combination with other agents, to treat depression disorders and associated maladies. ... University Of Utah Research Foundation

06/08/17 / #20170157285

In situ solidifying complex coacervates and methods of making and using thereof

. . Described herein are fluid complex coacervates that produce solid adhesives in situ. Oppositely charged polyelectrolytes were designed to form fluid adhesive complex coacervates at ionic strengths higher than the ionic strength of the application site, but an insoluble adhesive solid or gel at the application site. ... University Of Utah Research Foundation

05/18/17 / #20170135607

Method and system for analyzing gait and providing real-time feedback on gait asymmetry

A method and system for analyzing gait asymmetry between left and right feet of individuals by measuring and comparing stance phase time and/or stance phase force between left and right during gait, and providing real-time sensory feedback if stance phase time/force inequality exceeds a predetermined threshold.. . ... University Of Utah Research Foundation

05/18/17 / #20170135606

System, device, and method for measuring net load on a lower extremity

Implementations of the present disclosure relate to apparatuses, systems, and methods for measuring net load on a lower extremity. In one embodiment a bootcast may include a body and a sole. ... University Of Utah Research Foundation

05/04/17 / #20170122893

Interfacial nanofibril composite for selective alkane vapor detection

A nanofiber composite sensor for detecting alkanes can include a network of contacting nanofibers having multiple contact points. Each contact point can form an interfiber interface of interdigitated alkyl chains. ... University Of Utah Research Foundation

05/04/17 / #20170120078

Therapeutic ultrasound breast treatment

A therapeutic ultrasound breast treatment device (101) is disclosed. The device (101) can include a receptacle (130) to receive a breast of a patient therein. ... University Of Utah Research Foundation

04/27/17 / #20170113975

Methods of sintering dense zeta-phase tantalum carbide

A method of forming a sintered ζ-phase tantalum carbide can include assembling a particulate mixture including a tantalum hydride powder and a carbon source powder. The particulate mixture can be sintered to form a tantalum carbide having at least 70 wt. ... University Of Utah Research Foundation

04/27/17 / #20170113273

Molten salt de-oxygenation of metal powders

Methods of removing oxygen from a metal are described. In one example, a method (100) can include forming a mixture (110) including a metal, a calcium de-oxygenation agent, and a salt. ... University Of Utah Research Foundation

04/27/17 / #20170112940

Modified collagen hybridizing peptides and uses thereof

Disclosed are peptide conjugates comprising an active agent, a spacer moiety, and a peptide, wherein the peptide comprises the sequence (xaa1-xaa2-xaa3)n1-xaa4-xaa5-xaa6-(xaa7-xaa8-xaa9)n2, wherein xaa1, xaa2, xaa3, xaa4, xaa5, xaa6, xaa7, xaa8, xaa9 is glycine, proline, a modified proline or aza-glycine, and at least one of xaa1, xaa2, xaa3, xaa4, xaa5, xaa6, xaa7, xaa8, or xaa9 is aza-glycine. Disclosed are peptide conjugates comprising an active agent, a spacer moiety, and a peptide, wherein the peptide comprises the sequence (x1−y1−z1)-(x2−y2−z2)-(xn−yn−zn) (seq id no:1-39, 82), wherein n=1-41, and x, y, and z are glycine, proline, a modified proline and/or aza-glycine, and at least one of the amino acids in the sequence is aza-glycine. ... University Of Utah Research Foundation

04/20/17 / #20170110678

Dual-gate chemical field effect transistor sensor

A chemical sensing field effect transistor device is disclosed. The device can include a control gate structure interfacing a control side of a semiconductor channel region, a source region, and a drain region. ... University Of Utah Research Foundation

04/20/17 / #20170109674

Systems and methods for managing power generation resources

An optimal operating configuration for a power system may be derived from a continuous-time model of generation and ramping constraints of power generation units available within the power system. The optimal operating configuration may be leveraged to calculate a valuation metric for power generated by the power generating units. ... University Of Utah Research Foundation

04/20/17 / #20170108502

Biomarkers and methods for diagnosis of early stage pancreatic ductal adenocarcinoma

The present invention provides biomarker compositions and methods for the diagnosis and prognosis of pdac. In a particular embodiment, the invention provides methods and compositions for screening, diagnosis and prognosis of early stage, asymptomatic pdac.. ... University Of Utah Research Foundation

04/20/17 / #20170105932

Intraocular drug delivery device and associated methods

Devices, systems, and methods for delivery of an active agent from the lens capsule to a posterior segment of the eye of a subject can include an intraocular active agent delivery device including an active agent dispersed within a biodegradable active agent matrix. The active agent includes dexamethasone and the delivery device is adapted to fit within a lens capsule or ciliary sulcus of an eye. ... University Of Utah Research Foundation

04/13/17 / #20170103187

Disease therapy game technology

A video game in possession of and/or in the proximity of a patient. The patient computing system receives an indication that it is to begin a game, and executes the game using identified game parameters that are associated with the patient by a clinician as part of a disease therapy program. ... University Of Utah Research Foundation

04/13/17 / #20170102725

Systems and methods for power system management

An operating configuration for a power system during a particular time period may be derived from a net load forecast for the power system during the particular time period. The operating configuration may be based on characteristics of power generation units (pgus) available within the power system (e.g., power generators). ... University Of Utah Research Foundation

04/13/17 / #20170100375

Compositions and methods comprising 2-(acylamino)imidazoles

The present invention presents 2-(acylamino)imidazoles with therapeutic activity, including selective activity against cancer cells, and compositions comprising them. Methods of using and preparing the 2-(acylamino)imidazoles are also presented.. ... University Of Utah Research Foundation

04/06/17 / #20170095501

Pharmaceutical compositions composed of low molecular weight sulfated hyaluronan

Described herein are pharmaceutical compositions composed of low molecular weight sulfated hyaluronan.. . ... University Of Utah Research Foundation

03/30/17 / #20170089908

Systems and methods for label-free detection of analytes

Disclosed are methods of detecting an analyte of interest comprising introducing a sample comprising an analyte of interest to an antibody or antibody fragment; incubating the sample and antibody or antibody fragment under conditions sufficient to allow binding of the analyte of interest to the antibody or antibody fragment; and detecting the binding of the analyte of interest to the antibody or antibody fragment using a label-free second harmonic detection system. Also disclosed are methods of screening and diagnosing using antibodies or antibody fragments and a label-free second harmonic detection system.. ... University Of Utah Research Foundation

03/23/17 / #20170081637

Development of natural killer cells and functional natural killer cell lines

The invention relates to natural killer cells and methods for the development of immortalized natural killer cells and use of the natural killer cells. A growth and culture system is described that supports increased natural killer cell development, and provides for the establishment of continuous natural killer cell lines. ... University Of Utah Research Foundation

03/16/17 / #20170071540

High aspect ratio shadow mask and a method of making and using the same

A high aspect ratio shadow mask and a method of making and using the high aspect ratio shadow mask can provide multiple conductive trace pathways along high aspect ratio electrodes. The high aspect ratio shadow mask can include a substantially planar base layer and a plurality of hollow high aspect ratio projections extending from the substantially planar base layer. ... University Of Utah Research Foundation

03/09/17 / #20170067015

Electrophysiological recording system and methods of using same

The disclosure provided herein provides systems, devices, and methods for analyzing cultured cells. Also disclosed herein are systems, devices, and methods for analyzing interactions between two different groups of cells. ... University Of Utah Research Foundation

03/09/17 / #20170065602

Compounds with trpv4 activity, compositions and associated methods thereof

Compounds, compositions and methods useful for treating ocular diseases are provided. In particular, antagonists of trpv4, their synthesis, pharmaceutical compositions thereof and methods of treating ocular diseases such as glaucoma, are disclosed.. ... University Of Utah Research Foundation

03/02/17 / #20170059567

Methods and systems for electrochemically detecting or quantifying an analyte

Methods of electrochemically detecting or quantifying an analyte by coupling a plurality of redox-active agents (e.g., guanine-rich oligonucleotides) to the analyte are disclosed. More particularly, this application discloses affinity-based methods for isolating one or more analytes from a sample and subsequently detecting or determining the concentration of the one or more analytes. ... University Of Utah Research Foundation

03/02/17 / #20170058047

Method of detecting ocular diseases and pathologic conditions and treatment of same

Methods of detecting and treating diseases and pathological conditions of the eye are disclosed. In particular a genetic variant of the htra1 gene is correlated to age related macular degeneration (amd). ... University Of Utah Research Foundation

02/23/17 / #20170051280

Methods and compositions for inhibiting retinopathy of prematurity

Disclosed are vectors and compositions comprising a pol ii promoter and an shrna wherein the shrna has a sense rna strand and an antisense rna strand, wherein the sense and the antisense rna strands form an rna duplex, and wherein the sense rna strand comprises a nucleotide sequence identical to a target sequence in stat3, vegfr, or epor. Also disclosed are methods of treating retinopathy of prematurity (rop), methods of inhibiting expression of stat3, vegfr, and epor, and methods of regulating signaling events associated with intravitreal neovascularization (ivnv).. ... University Of Utah Research Foundation

02/23/17 / #20170051075

Method of detecting ocular diseases and pathologic conditions and treatment of same

Ocular diseases affecting the macula or the vasculature of the eye affect a wide variety of individuals. In particular, age-related macular degeneration (amd) is the most common cause of irreversible vision loss in the developed world and has a significant genetic predisposition. ... University Of Utah Research Foundation

02/16/17 / #20170044618

Methods and compositions involving intrinsic genes

Disclosed are compositions and methods related intrinsic gene sets and methods and compositions related to detecting and classifying cancer.. . ... University Of Utah Research Foundation

02/16/17 / #20170042662

Tissue stabilization system

Methods and systems are provided for tissue stabilization. Some aspects include a carrier member having a length, width, and thickness, wherein the length and width are each at least two times greater than the thickness; attachment members extending from the carrier member and that engage connective tissue; and stabilizing members, each of which can couple a respective attachment member to the carrier member and is substantially positionally fixed relative to the carrier member.. ... University Of Utah Research Foundation

02/09/17 / #20170035760

Galactokinase inhibitors for the treatment and prevention of associated diseases and disorders

Disclosed are inhibitors of human galactokinase of formula (1) that are useful in treating or preventing a galactokinase mediated disease or disorder, e.g., galactosemia. Also disclosed are a composition comprising a pharmaceutically acceptable carrier and at least one inhibitor of the invention, and a method of treating or preventing such disease or disorder in a mammal. ... University Of Utah Research Foundation

02/02/17 / #20170030960

Systems and methods for implementing s/sstdr measurements

. . Systems and methods which utilize spread spectrum sensing on live circuits to obtain information regarding a circuit under test are provided. In some embodiments s/sstdr testing may be utilized to obtain r, l, c and z measurements from circuit components. ... University Of Utah Research Foundation

02/02/17 / #20170030096

Elongate member reinforcement with a studded collar

An elongate member reinforcement system and associated methods are disclosed. The system can include an elongate member, a collar secured about an end portion of the elongate member, a support layer surrounding the end portion of the elongate member, and a structural filler disposed between the support layer and the end portion of the elongate member. ... University Of Utah Research Foundation

02/02/17 / #20170027503

Devices, systems, and methods for imaging and treating a selected tissue

A catheter for imaging and treating a selected tissue and method of use is provided. Imaging, and treatment assemblies may be co-located at a distal end of a single catheter. ... University Of Utah Research Foundation

02/02/17 / #20170027465

Systems and methods for characterizing the conductive properties of the heart

Electrophysiology mapping systems and methods that are used to determine longitudinal and transverse conduction velocities within myocardial tissue. The myocardial tissue can be contacted with at least three non-collinear electrodes. ... University Of Utah Research Foundation

01/26/17 / #20170021425

Production of substantially spherical metal powders

A method for producing a substantially spherical metal powder is described. A particulate source metal includes a primary particulate and has an average starting particle size. ... University Of Utah Research Foundation

01/26/17 / #20170020951

Neuropeptide analogs, compositions, and methods for treating pain

Neuropeptide analogs and compositions including neuropeptide analogs are described herein. Also provided are methods of producing and using the neuropeptide analogs and compositions including one or more neuropeptide analogs.. ... University Of Utah Research Foundation

01/26/17 / #20170020433

Fluid analysis device and associated systems and methods

A fluid analysis device including a fluid receipt chamber, a first capacitive element for measuring fluid flow into the fluid receipt chamber and a controller operatively coupled to the first capacitive element, wherein the controller is configured to measure a first capacitance of the first capacitive element.. . ... University Of Utah Research Foundation

01/12/17 / #20170010585

Methods and systems for generating a three-dimensional holographic mask

A system for surface patterning using a three dimensional holographic mask includes a light source configured to emit a light beam toward the holographic mask. The holographic mask can be formed as a topographical pattern on a transparent mask substrate. ... University Of Utah Research Foundation

01/12/17 / #20170007813

Multi-site electrode arrays and methods of making the same

A multi-site electrode array (100) can include a microneedle array and a set of electrically active sites (115). The microneedle array includes a plurality of microneedles (105) supported on a base substrate (110). ... University Of Utah Research Foundation

01/05/17 / #20170001970

Substituted benzohydrazide analogs as histone demethylase inhibitors

Benzohydrazide analogs, derivatives thereof, and related compounds, which are useful as inhibitors of lysine-specific histone demethylase, including lsd1 and lsd2; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of using the compounds and compositions to treat disorders associated with dysfunction of the lsd1 and/or lsd2.. . ... University Of Utah Research Foundation

01/05/17 / #20170000894

Compositions and methods for modifying the surface of cells and methods of use

Described herein are compounds, compositions and methods for modification of the surface of a living cell with a therapeutically relevant targeting moiety. Also described herein are methods for treating disease states, such as acute myocardial ischemia or infarction, with said compositions, in a subject.. ... University Of Utah Research Foundation








ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009



###

This listing is an abstract for educational and research purposes is only meant as a recent sample of applications filed, not a comprehensive history. Freshpatents.com is not affiliated or associated with University Of Utah Research Foundation in any way and there may be associated servicemarks. This data is also published to the public by the USPTO and available for free on their website. Note that there may be alternative spellings for University Of Utah Research Foundation with additional patents listed. Browse our Agent directory for other possible listings. Page by FreshPatents.com

###