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University Of Washington patents


Recent patent applications related to University Of Washington. University Of Washington is listed as an Agent/Assignee. Note: University Of Washington may have other listings under different names/spellings. We're not affiliated with University Of Washington, we're just tracking patents.

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Systems and methods for enabling user interactions with wireless tags

There is provided a system including a wireless tag reader, a first wireless antenna, a wireless tag including an integrated circuit (ic), a conductive element electronically connecting the wireless tag to the first wireless antenna, a non-transitory memory storing an executable code, a hardware processor executing the executable code to transmit an interrogation signal, receive a tag signal from the wireless tag electronically connected to the first wireless antenna in response to the interrogation signal, the tag signal including a wireless tag identification (id) uniquely identifying the wireless tag, and determine an interaction by a user with the wireless tag based on the tag signal.. . ... University Of Washington

Compositions and methods for treating toxoplasmosis, cryptosporidiosis and other apicomplexan protozoan related diseases

The present disclosure is directed to compositions and methods for inhibiting either toxoplasma gondii (t. Gondii) calcium dependent protein kinases (tgcdpks) or cryptosporidium parvum (c. ... University Of Washington

Bumped kinase inhibitor compositions and methods for treating cancer

The present disclosure is generally directed to bumped kinase inhibitor (bki) compositions and methods for treating cancer.. . ... University Of Washington

Radio frequency communication devices having backscatter and non-backscatter communication modes and hardware re-use

Backscatter communication offers the potential for significant energy savings compared to conventional wireless links such as bluetooth, zigbee, wifi, etc. However, backscatter communication requires the presence of a carrier source in the environment at an appropriate frequency. ... University Of Washington

Random access of data encoded by polynucleotides

This disclosure describes frameworks and techniques related to the random access of digital data encoded by polynucleotides. Digital data of a data file can be encoded as a series of nucleotides and one or more polynucleotide sequences can be generated that encode the digital data for the data file. ... University Of Washington

A system and method for direct-sample extremely wide band transceiver

Systems and methods for direct sample, extremely wideband transceivers are disclosed. An example transceiver includes an antenna, an n bit analog to digital converter a digital signal processor, a digital to analog converter, and an adder. ... University Of Washington

Methods and systems for performing digital measurements

Methods, devices and systems for performing digital measurements are provided.. . ... University Of Washington

Parastomal hernia support harness

Parastomal hernia support devices are disclosed herein. A parastomal hernia support device configured in accordance with embodiments of the present technology can include, for example, a support assembly including a generally rigid outer portion and a generally flexible inner portion having an aperture configured to be aligned with a stoma of the user. ... University Of Washington

Dental demineralization detection, methods and systems

Methods and systems for detecting early stage dental caries and decays are provided. In particular, in an embodiment, laser-induced autofluorescence (af) from multiple excitation wavelengths is obtained and analyzed. ... University Of Washington

Apparatuses, systems, and methods for communicating using mimo and spread spectrum coding in backscatter of ambient signals

Apparatuses, systems, ambient rf backscatter transceivers, and methods for communicating using mimo and spread spectrum coding of backscattered ambient rf signals are described. An example system may include an ambient rf backscatter transceiver that include an antenna configured to receive a backscattered ambient radio frequency (rf) signal, and a receiver coupled to the antenna. ... University Of Washington

Nuclease-mediated regulation of gene expression

The present disclosure is in the field of genome engineering, particularly targeted modification of the genome of a hematopoietic cell.. . ... University Of Washington

Mic-binding antibodies and methods of use thereof

The technology described herein relates to antibodies and/or polypeptides which bind to mic and inhibit mic shedding. Methods of using such antibodies and/or polypeptides for the treatment of cancer are also described herein.. ... University Of Washington

Methods for the prevention or treatment of heart failure

The disclosure provides methods of preventing or treating heart failure in a mammalian subject. The methods comprise administering to the subject an effective amount of an aromatic-cationic peptide to subjects in need thereof.. ... University Of Washington

Systems and methods of forming enhanced medical images

Systems and methods of producing medical images of a subject are disclosed herein. In one embodiment, structural data and vascular data are acquired from a region of interest in the subject. ... University Of Washington

08/16/18 / #20180232052

Integration of auxiliary sensors with point cloud-based haptic rendering and virtual fixtures

Apparatus and methods for generating virtual environment displays based on a group of sensors are provided. A computing device can receive first data about an environment from a first group of one or more sensors. ... University Of Washington

08/16/18 / #20180231705

Photoluminescent semiconductor nanocrystal-based luminescent solar concentrators

The present disclosure describes luminescent solar concentrators that include photoluminescent nanoparticles. The photoluminescent nanoparticles include a semiconductor nanocrystal that sensitizes the luminescence of a defect. ... University Of Washington

08/16/18 / #20180228842

Biologically relevant orthogonal cytokine/receptor pairs

Engineered orthogonal cytokine receptor/ligand pairs, and methods of use thereof, are provided.. . ... University Of Washington

08/09/18 / #20180227559

Myopia-safe video displays

In a first aspect, the present invention provides methods for creating video signals including (a) receiving an input video signal including an input red component, an input green component, and an input blue component; (b) determining (i) that a magnitude of the input red component is greater than a magnitude of the input green component and (ii) a differential between the magnitude of the input red component and the magnitude of the input green component; and (c) sending an output video signal including an output red component, an output green component, and an output blue component, where at least one of the following is true: (i) the output red component is decreased by a fractional amount relative to the input red component based on the differential; and/or (ii) the output green component is increased by a fractional amount relative to the input green component based on the differential, and the output blue component is increased by a fractional amount relative to the input blue component based on the differential.. . ... University Of Washington

08/09/18 / #20180224492

Detecting user-driven operating states of electronic devices from a single sensing point

An apparatus including a sensing device configured to be coupled to an electrical outlet is provided. The sensing device can include a data acquisition receiver configured to receive electrical noise via the electrical outlet when the sensing device is coupled to the electrical outlet. ... University Of Washington

08/09/18 / #20180221464

Immunogenic compositions, antigen screening methods, and methods of generating immune responses

An immunogenic composition is provided herein. The immunogenic compositions are used to identify and select immunogenic antigens that elicit immune responses in a subject and may be subsequently used in multi-antigen vaccine compositions against one or more diseases or conditions. ... University Of Washington

08/02/18 / #20180217158

Methods for detecting anti-he4 antibodies and methods of diagnosis and/or prognosis of conditions associated with he4-expressing cells

The present invention features, inter alia, compositions and methods related to the detection of he4-expressing tumor cells in a subject. The methods include detection of anti-he4 antibodies in a biological sample obtained from the subject. ... University Of Washington

07/26/18 / #20180209989

Methods for assaying palmitoyl protein thioesterase 1 and tripeptidyl peptidase activity in dried blood spots for detection of neuronal ceroid lipofuscinoses in newborns

The present disclosure provides assays for lysosomal enzymes, specifically palmitoyl protein thioesterase 1 (ppt1) and tripeptidyl peptidase 1 (tpp1), using, for example, tandem mass spectrometry. The assays involve the detection of enzymatic products obtained through the action of the lysosomal enzymes on new enzyme substrates, and can be used for quantitative enzyme activity measurements. ... University Of Washington

07/26/18 / #20180209878

Ultrasound system for shearing cellular material in a microplate

Disclosed embodiments include illustrative piezoelectric element array assemblies, methods of fabricating a piezoelectric element array assembly, and systems and methods for shearing cellular material. Given by way of non-limiting example, an illustrative piezoelectric element array assembly includes at least one piezoelectric element configured to produce ultrasound energy responsive to amplified driving pulses. ... University Of Washington

07/26/18 / #20180207006

Robust adaptable foot prosthesis

A device is provided to allow adaptation of a prosthetic or robotic foot in the medial-lateral direction, including pronation and supination of the foot using a series of articulations. Articulations are permitted in the disclosed device due to linkage systems positioned at various locations of the prosthetic foot. ... University Of Washington

07/26/18 / #20180206971

Pro-healing elastic angiogenic microporous vascular graft

Synthetic polymeric vascular grafts that promote endothelial healing and methods of their preparation and use are provided.. . ... University Of Washington

07/19/18 / #20180200172

Reagents and methods for whitening teeth

Reagents and methods for whitening teeth using biomineralizing peptides are described.. . ... University Of Washington

07/12/18 / #20180199015

Scanning laser projection display for small handheld devices

Image projection devices, high-speed fiber scanned displays and related methods for projecting an image onto a surface and interfacing with the projected image are provided. A method for projecting one or more images and obtaining feedback with an optical input-output assembly is provided. ... University Of Washington

07/12/18 / #20180193457

Compositions and methods for treatment and prevention of uropathogenic e. coli infection

Methods and antibody compositions that displace mannose from the binding pocket of fimbrial adhesin fimh of enterobacteria, including uropathogenic e. Coli, klebsiella oxytoca, or klebsiella pneumoniae, can be used to disrupt or prevent the attachment of a single layer of bacteria to a mannose-coated surface, or to disrupt or prevent the formation of a multilayer biofilm. ... University Of Washington

07/12/18 / #20180193419

Compositions, kits, and methods using interleukin-17c to promote neural growth and/or neural survival

The present disclosure provides compositions, kits, and methods of promoting neural growth and/or neural survival using il-17c. The compositions, kits, and methods can be used to promote neural growth and/or neural survival in a variety of conditions where such growth and survival is beneficial.. ... University Of Washington

07/05/18 / #20180188085

Sensing events affecting liquid flow in a liquid distribution system

By monitoring pressure transients in a liquid within a liquid distribution system using only a single sensor, events such as the opening and closing of valves at specific fixtures are readily detected. The sensor, which can readily be coupled to a faucet bib, transmits an output signal to a computing device. ... University Of Washington

07/05/18 / #20180187174

Therapeutic nuclease compositions and methods

Hybrid nuclease molecules and methods for treating an immune-related disease or disorder in a mammal, and a pharmaceutical composition for treating an immune-related disease in a mammal.. . ... University Of Washington

07/05/18 / #20180185458

Compositions and methods for treating celiac sprue disease

Disclosed herein are compositions and methods for treating celiac sprue.. . ... University Of Washington

06/28/18 / #20180183269

Energy harvesting and control for sensor node

An integrated circuit, such as included as a portion of a sensor node, can include a regulator circuit having an input coupleable to an energy harvesting transducer. The integrated circuit can include a wireless receiver circuit coupled to the regulator circuit and configured to wirelessly receive at least enough operating energy to establish operation of the sensor node without requiring the energy harvesting transducer. ... University Of Washington

06/21/18 / #20180169365

Intubating neonatal laryngeal mask airway

An intubating neonatal laryngeal mask airway includes an elongated body having a palate side and a lingual side. A cuff is coupled to an elongated body opposite a distal end of the elongated body. ... University Of Washington

06/14/18 / #20180164329

Prostate cancer-associated secreted proteins

Methods are provided for treating a subject with prostate cancer and/or diagnosing a subject at risk for prostate cancer, which can include measuring increased expression of at least two prostate cancer-related molecules in a sample obtained from a subject, including the prostate cancer-related molecules agr2, agr3, crisp3, ccl3, ceacam5, ceacam6, il24, mmp9, cxcl14, cd90, postn, and sfrp4. The methods can include administering at therapy to a subject with prostate cancer. ... University Of Washington

06/14/18 / #20180161188

Energy storage device for an exoskeleton

Disclosed herein is a leg exoskeleton configured to aid motion (e.g., walking) of a user in need thereof. In particular, the exoskeleton includes a belt configured to attach the exoskeleton to the waist of a user. ... University Of Washington

05/31/18 / #20180148488

Novel micro-dystrophins and related methods of use

Nucleotide sequences including a micro-dystrophin gene are provided. The micro-dystrophin genes may be operatively linked to a regulatory cassette. ... University Of Washington

05/24/18 / #20180142293

Methods of lowering the error rate of massively parallel dna sequencing using duplex consensus sequencing

Next generation dna sequencing promises to revolutionize clinical medicine and basic research. However, while this technology has the capacity to generate hundreds of billions of nucleotides of dna sequence in a single experiment, the error rate of approximately 1% results in hundreds of millions of sequencing mistakes. ... University Of Washington

05/17/18 / #20180137234

Computational design of self-assembling cyclic protein homo-oligomers

Described herein are polypeptides capable of self-assembling to form homo-oligomers, and methods for designing such polypeptides.. . ... University Of Washington

05/17/18 / #20180133520

Methods for characterizing nonlinear fields of a high-intensity focused ultrasound source and associated systems and devices

The present technology is directed to methods for characterizing nonlinear ultrasound fields and associated systems and devices. In several embodiments, for example, a method of calculating output of a high intensity focused ultrasound (hifu) device comprises treating a target site with a multi-element hifu array. ... University Of Washington

05/03/18 / #20180119202

Proximity-enhanced nucleic acid-amplified protein detection

The present technology is related to methods and compositions for detecting, and optionally quantifying, one or more analytes of a sample using nucleic acids. In some embodiments, the methods include generating a complex of a plurality of peptides, an analyte, a first nucleic acid, and a second nucleic acid, each nucleic acid conjugated to a binder peptide. ... University Of Washington

05/03/18 / #20180117536

Ceramic proton-conducting membranes

Disclosed herein are ceramic selective membranes and methods of forming the ceramic selective membranes by forming a selective silica ceramic on a porous membrane substrate. Representative ceramic selective membranes include ion-conductive membranes (e.g., proton-conducting membranes) and gas selective membranes. ... University Of Washington

05/03/18 / #20180117535

Ceramic proton-conducting membranes

Disclosed herein are ceramic selective membranes and methods of forming the ceramic selective membranes by forming a selective silica ceramic on a porous membrane substrate. Representative ceramic selective membranes include ion-conductive membranes (e.g., proton-conducting membranes) and gas selective membranes. ... University Of Washington

05/03/18 / #20180117125

Vectors and methods for regenerative therapy

An expression vector capable of disrupting the silencing of cell cycle genes in adult cells, such as adult cardiac myocytes and other quiescent cells in terminally differentiated tissues, comprising: (a) a nucleic acid sequence encoding lysine-specific demethylase 4d (kdm4d); (b) a promoter that induces or effects overexpression of kdm4d, wherein the promoter is operably linked to the nucleic acid sequence; and (c) a regulatory element that inducibly represses the overexpression of kdm4d. The vector can be administered to a subject in a method for inducing tissue-specific hyperplasia in a mammal, including cardiomyocyte proliferation. ... University Of Washington

05/03/18 / #20180116744

Ferromagnetic shaped memory alloy nano-actuator and method of use

Nano-actuators having a helical member formed with a ferromagnetic shape memory alloy (fsma) are disclosed that are elastically deformable between a compressed state and an expanded state by the application of a magnetic field. The nano-actuators may include a ferromagnetic head portion, that may be formed from the fsma or from another material. ... University Of Washington

04/19/18 / #20180104325

Methods and compositions for activation of innate immune responses through rig-i like receptor signaling

Compositions and methods are provided that enable activation of innate immune responses through rig-i like receptor signaling. The compositions and methods incorporate synthetic nucleic acid pathogen associated molecular patterns (pamps) that comprise elements initially characterized in, and derived from, the hepatitis c virus genome.. ... University Of Washington

04/19/18 / #20180103834

Adaptive control of a fiber scanner with piezoelectric sensing

Improved systems, methods, and devices relating to optical fiber scanners are provided. In one aspect, a scanning apparatus includes an optical fiber and a piezoelectric actuator coupled to the optical fiber to deflect a distal end of the optical fiber in a scanning pattern. ... University Of Washington

04/12/18 / #20180100183

Isotachophoresis enhanced isothermal nucleic acid amplification

The present disclosure relates generally to the integration of isotachophoresis (itp) and isothermal nucleic acid amplification methods such as recombinase polymerase amplification (rpa). One aspect of the disclosure relates to a method for concentrating and amplifying a nucleic acid, the method including an isotachophoresis device, the isotachophoresis device including a porous matrix, and first and second electrodes, having a leading electrolyte, a trailing electrolyte and a set of isothermal nucleic acid amplification reaction reagents disposed in the porous matrix as described herein, and applying a voltage across the first electrode and the second electrode for a time sufficient to provide a first isotachophoresis (itp) plug comprising an amplification product of the nucleic acid, wherein the concentration of the nucleic acid is substantially higher in the first ftp plug than in the first and/or second fluids outside of the first itp plug.. ... University Of Washington

04/12/18 / #20180098955

Methods for the treatment and prevention of age-related retinal dysfunction

A method of treating or preventing age-related retinal dysfunction involves administering to a patient a pharmaceutically effective amount of a synthetic retinal derivative repeatedly over a duration of at least about 3 months. Effective synthetic retinal derivatives include 9-cis-retinyl esters, 11-cis-retinyl esters, derivatives and congeners thereof, and combinations thereof. ... University Of Washington

04/05/18 / #20180097396

Systems and methods for direct estimation of battery parameters using only charge/discharge curves

Electrochemical models for the lithium-ion battery are useful in predicting and controlling its performance. The values of the parameters in these models are vital to their accuracy. ... University Of Washington

03/29/18 / #20180090777

Ceramic proton-conducting membranes

Disclosed herein are ceramic selective membranes and methods of forming the ceramic selective membranes by forming a selective silica ceramic on a porous membrane substrate. Representative ceramic selective membranes include ion-conductive membranes (e.g., proton-conducting membranes) and gas selective membranes. ... University Of Washington

03/29/18 / #20180088308

Inverted light-sheet microscope

Devices and techniques for a light sheet microscope device are generally described. In some examples, the light sheet microscope may comprise a motorized movable stage comprising an optically clear glass plate. ... University Of Washington

03/29/18 / #20180086713

Cgas in systemic lupus erythematosus (sle)

The present invention provides therapeutic strategies for treatment of severe debilitating diseases associated with ifn-i due to cgas activation. In one aspect, the invention provides compounds of formula (i): [formula should be inserted here] and pharmaceutical uses thereof. ... University Of Washington

03/22/18 / #20180080863

Optical painting and fluorescence-activated sorting of adherent cells

The present disclosure provides a method of optically marking and sorting adherent cells. In some aspects, the method comprises: providing a plurality of adherent cells attached to a substrate, each adherent cell of the plurality of adherent cells comprising an optical marker; selectively applying light energy to a subset of the plurality of adherent cells; detaching the plurality of adherent cells from the substrate; and sorting the plurality of adherent cells.. ... University Of Washington

03/08/18 / #20180068060

Integrated system for nucleic acid-based storage of digital data

In some embodiments, systems and methods for storing and/or retrieving digital information in a nucleic acid library are provided. In some embodiments, an integrated system comprising a nucleic acid synthesis device, a nucleic acid sequencing device, a computing device, and a nucleic acid library is provided. ... University Of Washington

03/08/18 / #20180066299

Micro-and nanopatterned substrates for cell migration and uses thereof

The present invention generally relates to the field of cell growth and tissue engineering, in particular, an engineered biomimetic culture platform (bcp) that has a nanotextured and micropatterned surface that provides both chemical and mechanical cues designed to mimic the structure of the in vivo extracellular micro-environment. The bcp can be used in assays to assess the migratory behavior and/or potential of a population of cells, such as tumor cells, as well as in screening assays for diagnostic and/or prognostic purposes, or to identify agents that modify the migratory behavior or the epithelial-to-mesenchymal transition (emt) of cells. ... University Of Washington

03/08/18 / #20180066022

Compositions and methods for intravitreal delivery of polynucleotides to retinal cones

Methods and compositions are provided for intravitreally delivering a polynucleotide to cone photoreceptors. Aspects of the methods include injecting a recombinant adeno-associated virus comprising a polynucleotide of interest into the vitreous of the eye. ... University Of Washington

03/01/18 / #20180057542

Theragnostic particles

The present invention provides viral-based nanoparticles for therapeutic and diagnostic use, and methods for making and using the nanoparticles. Specifically, such nanoparticles comprise decoration-competent viral particles shells such as expanded capsids of phages, stabilized with engineered decoration proteins that have been linked to one or more compounds not naturally occurring on a wild type viral capsid.. ... University Of Washington

02/15/18 / #20180046704

Systems and methods for selection-based contextual help retrieval

Described herein are systems and methods for selection-based contextual help retrieval. One example method involves (a) receiving first-query data including contextual data, the contextual data indicating a user-interface element type, a user-interface element location, and user-interface element text; (b) determining at least one first-query response based on at least the contextual data; and (c) causing an indication of the determined at least one first-query response to be provided via an output device.. ... University Of Washington

02/15/18 / #20180043778

Electrochemical cell diagnostic systems and methods using second order and higher harmonic components

Electrochemical cell diagnostic systems and methods are described. Examples include systems having a signal generator configured to apply a stimulus having a stimulus frequency to at least one electrochemical cell. ... University Of Washington

02/15/18 / #20180043029

Stabilized polymeric carriers for therapeutic agent delivery

Polymeric carriers for the delivery of therapeutic agents and methods for making and using the same. The polymeric carriers include copolymers, diblock copolymers, polymeric architectures that include the copolymers and diblock copolymers, and particles assemblies comprising the copolymers, diblock copolymers, and polymeric architectures that include the copolymers.. ... University Of Washington

02/15/18 / #20180042473

Methods and systems for enhancing microangiography image quality

Systems and methods for enhancing quality of a flow image of a sample of a subject are provided. The method comprises acquiring a first flow image from a plurality of first omag scans of the sample, and acquiring a structure image from a second omag scan of the sample. ... University Of Washington

02/08/18 / #20180038792

Removable chromatic witness assembly, system, and method to monitor thermal events and impact events on a composite structure

There is provided a removable chromatic witness assembly, system, and method to monitor thermal events and impact events on a surface of a composite structure. The removable chromatic witness assembly has a plurality of chromatic witness geometric configurations separately coupled in an arrangement to one or more portions of a polymeric film layer. ... University Of Washington

02/08/18 / #20180037961

Primers, probes and methods for sensitive, specific detection and monitoring of hiv-1 and hcv

Primers and probes for detecting an rna virus, including hiv, hiv-1 subtypes of the m and o groups, and hcv, in a sample. The primers and probes can be used for monitoring the efficacy of anti-retroviral treatment in a subject infected with hiv and/or hcv, and for detecting acute hiv-1 infection, and/or acute hcv infection, in a subject. ... University Of Washington

02/01/18 / #20180028794

Drainage systems for excess body fluids and associated methods

Drainage systems for excess body fluids and associated methods are disclosed herein. A body fluid drainage system in accordance with an embodiment of the present technology, for example, can include a catheter that has an exterior surface, a proximal portion, and a distal portion opposite the proximal portion. ... University Of Washington

01/25/18 / #20180025791

Plasma confinement system and methods for use

. . A plasma confinement system is provided that includes a confinement chamber that includes one or more enclosures of respective helicity injectors. The one or more enclosures are coupled to ports at an outer radius of the confinement chamber. ... University Of Washington

01/18/18 / #20180016339

Soluble mic neutralizing monoclonal antibody for treating cancer

Described herein are compositions and methods relating to antibodies that bind soluble mic (smic), e.g. For the treatment of mic-positive cancers.. ... University Of Washington

01/11/18 / #20180011101

Materials and methods for detecting androgen receptor splice variants and uses thereof

The present disclosure relates to materials and methods for evaluating prostate cancer using binding entities (such as antibodies) that bind to the n-terminus and the c-terminus of androgen receptor. Prostate samples are histochemically labeled for the n-terminus and the c-terminus of androgen receptor, and a ratio between the binding of the n- and c-terminal antibodies is determined.. ... University Of Washington

01/11/18 / #20180011016

System and method for immersion flow cytometry

An immersion cytometry system (200, 250) having a primary focusing optic immersed in a fluid stream (209) containing suspended particles (212). The system includes a light source (202) configured to illuminate a sensing region in the fluid stream that includes a focus of the primary optic. ... University Of Washington

01/11/18 / #20180008671

Prolonged anti-diabetic effect of fibroblast growth factor 1 (fgf1)

Disclosed are compositions and methods for inducing sustained diabetes remission by single administration of fgf1 to the brain. The composition and methods described herein result in basal glucose clearance by using a dosage of fgf1 that is lower than that needed for systemic efficacy and is devoid of the risk of hypoglycemia and changes in body weight, food intake, hepatic glucose production, insulin secretion or insulin sensitivity.. ... University Of Washington

01/04/18 / #20180001544

Method for solid freeform fabrication

The present invention provides methods, processes, and systems for the manufacture of three-dimensional articles made of polymers using 3d printing. A layer of prepolymer is deposited on a build plate to form a powder bed. ... University Of Washington

12/28/17 / #20170370387

Active control of vortices for skin friction reduction

Systems and method for active control of stationary vortices for aerodynamic structures are disclosed herein. In one embodiment, a method for active control of vortices over a solid surface includes: generating vortices proximate to the solid surface; sensing locations of vortices by printed skin sensors; and maintaining the vortices in their fixed spanwise positions with respect to the solid surface by actuation of printed skin actuators.. ... University Of Washington

12/28/17 / #20170369892

Hormone degradable crispr-based transcription factors

Synthetic signal transduction systems are provided. The synthetic signal transduction system may be a hormone degradable crispr-based transcription factor including a nuclease null cas9 protein, a nuclear localization signal, a phytohormone degron, and a transcriptional regulation domain. ... University Of Washington

12/28/17 / #20170369558

Neutralizing antibodies to hiv-1 and their use

Monoclonal neutralizing antibodies are disclosed that specifically bind to the cd4 binding site of hiv-1 gp120. Monoclonal neutralizing antibodies also are disclosed that specifically bind to hiv-1 gp41. ... University Of Washington

12/28/17 / #20170367838

Devices and methods for metatarsophalangeal arthroplasty procedures

The present technology relates generally to devices and methods for arthroplasty procedures. In some embodiments, for example, a device is disclosed for use during an arthroplasty procedure of a joint of a patient, the joint extending between a first joint end of a first bone and an abutting second joint end of a second bone of the patient. ... University Of Washington

12/21/17 / #20170363648

Biosensors engineered from conditionally stable ligand-binding domains

Disclosed is a biosensor engineered to conditionally respond to the presence of specific small molecules, the biosensors including conditionally stable ligand-binding domains (lbds) which respond to the presence of specific small molecules, wherein readout of binding is provided by reporter genes or transcription factors (tfs) fused to the lbds.. . ... University Of Washington

12/21/17 / #20170362635

Muscle-specific crispr/cas9 editing of genes

Pharmaceutical compositions including a muscle-specific nuclease cassette, one or more guide rna cassettes, and a delivery system for delivery of the muscle-specific nuclease cassette and the one or more grna cassettes are provided. The pharmaceutical composition may also include a mutation-corrected dna template including a modification to be made in a target nucleic acid sequence. ... University Of Washington

12/21/17 / #20170360886

Methods for treating and preventing cardiomyopathy

Methods for treating patients having a cardiomyopathy are provided. Additionally, methods for prophylactically treating patients at risk of developing a cardiomyopathy are provided. ... University Of Washington

12/07/17 / #20170347951

Systems and methods of identifying motion of a subject

Systems and methods of identifying medical disorders in one or more subjects are disclosed herein. In one embodiment, sound is transmitted toward a subject and at least a portion of the sound reflected by the subject and is acquired as echo data. ... University Of Washington

11/30/17 / #20170342316

Nanoparticles for photovoltaic and led devices and methods of making the same

The present disclosure relates to a composition that includes a particle and a surface species, where the particle has a characteristic length between greater than zero nm and 100 nm inclusively, and the surface species is associated with a surface of the particle such that the particle maintains a crystalline form when the composition is at a temperature between −180° c. And 150° c.. ... University Of Washington

11/30/17 / #20170342126

Hla-dr binding peptides and their uses

The present invention provides hla-dr (mhc class ii) binding peptides derived from the ovarian/breast cancer associated antigens, human epidermal growth factor receptor 2 (her-2/neu), carcinoembryonic antigen (cea), insulin growth factor binding protein 2 (igfbp-2), and cyclin d1. The immunogenic peptides can be used in cancer vaccines.. ... University Of Washington

11/30/17 / #20170340390

Computer-assisted osteocutaneous free flap reconstruction

Example methods and systems to facilitate osteocutaneous free flap reconstructions are provided. One example method involves causing a surgical navigation system to display a representation of a patient undergoing surgery; receiving input data representing one or more osteotomies made during the surgery to form a defect within the patient; determining a donor site for a bone graft having a contour that corresponds to the defect within the patient using a geometric alignment algorithm to identify, as the donor site, a portion of the bone graft that virtually aligns with the defect; generating a virtual template representing the bone graft; displaying the generated virtual template representing the bone graft within the representation of the patient as a navigational guide for harvesting of the bone graft; and displaying the generated virtual template positioned into the defect within the representation as a navigational guide for reconstructing the defect using the harvested bone graft.. ... University Of Washington

11/16/17 / #20170331509

Ambient backscatter tranceivers, apparatuses, systems, and methods for communicating using backscatter of ambient rf signals

Apparatuses, systems, ambient backscatter transceivers, and methods for modulating a backscatter of an ambient rf signal are described. An example system may include an ambient backscatter transceiver comprising an antenna that is configured to receive a backscattered ambient radio frequency (rf) signal. ... University Of Washington

11/16/17 / #20170328834

Systems, devices, and methods for separating, concentrating, and/or differentiating between cells from a cell sample

Embodiments are generally related to differentiating and/or separating portions of a sample that are of interest from the remainder of the sample. Embodiments may be directed towards separating cells of interest from a cell sample. ... University Of Washington

11/16/17 / #20170327813

3d printable hydrogel materials

Hydrogel compositions including a polymer uniformly embedded with a loading agent are provided. Also provided are methods for extrusion printing hydrogel compositions to provide extruded hydrogel compositions, which can be crosslinked to provide crosslinked hydrogel structures. ... University Of Washington

11/16/17 / #20170326790

Additive manufacturing using stimuli-responsive high-performance polymers

The present invention provides high performance polymer (hpp) compositions, methods, processes, and systems for the manufacture of three-dimensional articles made of polymers using molding or 3d printing. The hpp compositions comprise a first hpp dissolved in a solvent and a second hpp present as a solid having particular particle size.. ... University Of Washington

11/09/17 / #20170323441

Filter-free devices and systems for measuring fluorescence of a microfluidic assay and associated methods of use

The present technology relates generally to devices, systems, and methods for detecting an analyte from a microfluidic assay. In some embodiments, a method for detecting the analyte includes binding an analyte and a plurality of quantum dots to a detection region of a porous membrane of a microfluidic device. ... University Of Washington

11/09/17 / #20170322229

High affinity vitamin d3 binding proteins

The present disclosure provides isolated polypeptides with vitamin d3 binding activity and methods for their use as detection agents. In another aspect, the invention provides recombinant expression vector comprising an isolated nucleic acid of the invention operably linked to a control sequence. ... University Of Washington

10/26/17 / #20170310889

Extended depth of focus for high-resolution optical image scanning

Methods and systems for acquiring and/or projecting images from and/or to a target area are provided. Such a method or system can includes an optical fiber assembly which may be driven to scan the target area in a scan pattern. ... University Of Washington

10/26/17 / #20170307313

Baffled-tube ram accelerator

A baffled ram accelerator system includes a ram accelerator tube with an inner surface and an outer surface and a plurality of baffles disposed on the inner surface. The plurality of baffles forms a sequential series of propellant chambers along the longitudinal axis of the ram accelerator tube. ... University Of Washington

10/26/17 / #20170306029

Wnt signaling agonist molecules

Wnt signaling agonist compositions and methods for their use are provided. Wnt signaling agonists of the invention comprise a frizzled binding moiety, which is fused or conjugated to an lrp5 or lrp6 binding moiety.. ... University Of Washington

10/12/17 / #20170294015

Systems and methods for quantitative assessment of microvasculature using optical coherence tomography angiography

A five-index quantitative analysis of oct angiograms is disclosed. One method of analyzing an anatomical region of interest of a subject includes acquiring vascular image data from the region of interest and generating a binary vasculature map from the vascular image data. ... University Of Washington

10/12/17 / #20170292160

Methods for diagnosing and treating eye-length related disorders

The invention provides to methods for diagnosing eye-length related disorders, including myopia. The invention also provides methods for treating and limiting eye-length related disorders, including myopia. ... University Of Washington

10/12/17 / #20170290992

Systems and methods for inhibiting heterotopic ossification

Systems and methods for mitigating the formation of heterotopic ossification lesions by delivering a neuromuscular inhibitor employ a delivery device to distribute injection of the neuromuscular inhibitor. A delivery device for delivering the neuromuscular inhibitor can include an injector body, a device body for spacing the injector body from a target delivery location, and a plurality of needles; or can include an injector guide having multiple guide holes and an injector needle for delivering the neuromuscular inhibitor via the guide holes.. ... University Of Washington

10/12/17 / #20170290986

Ampule autoinjector systems and methods

An autoinjector is described that includes an outer body, a first trigger, an output needle, and a first compartment. The first compartment is positioned within the outer body and includes (i) a main body, (ii) a first biasing member coupled to the first trigger, and (iii) a protrusion positioned at a distal end of the main body. ... University Of Washington

10/12/17 / #20170290644

Medical implant with discontinuous osseointigrative surface

A medical implant includes a base portion configured for implantation into a bone of a patient. The base portion is formed from an electrically insulating and biocompatible base material with retaining features on an outer surface of the base portion for gripping the bone in the patient and at least two discontinuous regions formed of titanium on the outer surface.. ... University Of Washington

10/05/17 / #20170283475

Cancer vaccine compositions and methods of use thereof

The present application describes compositions that include an epitope of a peptide that elicits an immune response in a subject following administration. The compositions described herein include nucleic acids. ... University Of Washington

09/28/17 / #20170276578

Expansion microscopy methods and kits

Methods and kits useful in expansion microscopy are described. In particular, the present disclosure relates to methods and kits for expanding or enlarging fixed samples of interest for microscopy by synthesizing a water-swellable compound within a fixed sample, which can be physically expanded, resulting in physical magnification of the sample. ... University Of Washington

09/28/17 / #20170275279

Specific inhibitors of methionyl-trna synthetase

The present disclosure is generally directed to compositions useful in the inhibition of metrs and methods for treating diseases that are ameliorated by the inhibition of metrs.. . ... University Of Washington

09/28/17 / #20170274046

Compositions and methods for diagnosis and treatment of neurological disease

Provided herein are methods, assays and compositions relating to the treatment of neurological diseases and disorders, particularly by modulating expression and/or activity of bif-1.. . ... University Of Washington

09/28/17 / #20170273699

Ultrasound based method and apparatus for stone detection and to facilitate clearance thereof

Described herein are methods and apparatus for detecting stones by ultrasound, in which the ultrasound reflections from a stone are preferentially selected and accentuated relative to the ultrasound reflections from blood or tissue. Also described herein are methods and apparatus for applying pushing ultrasound to in vivo stones or other objects, to facilitate the removal of such in vivo objects.. ... University Of Washington

09/28/17 / #20170273539

Phone adapter for flexible laryngoscope and rigid endoscopes

An adapter for endoscopy can operably connect camera features and light source features of a portable electronic device with a respective viewfinder and illumination element of a medical endoscope. Systems including an endoscope, adapter, and handheld electronic device with a microphone, light source, and camera can, when connected, be used to perform stroboscopic endoscopic examinations.. ... University Of Washington

09/21/17 / #20170266350

Functionalized zwitterionic and mixed charge polymers, related hydrogels, and methods for their use

Functionalized zwitterionic and mixed charge polymers and copolymers, methods for making the polymers and copolymers, hydrogels prepared from the functionalized zwitterionic and mixed charge polymers and copolymers, methods for making and using the hydrogels, and zwitterionic and mixed charge polymers and copolymers for administration for therapeutic agents.. . ... University Of Washington

09/21/17 / #20170266269

Methods of identifying antigens for vaccines

The methods, processes, and systems described herein include identifying an epitope of a peptide that may elicit an immune response in a subject. Often the methods, systems and processes may include designing and producing a composition comprising an epitope of a peptide identified using the methods or processes described herein.. ... University Of Washington

09/14/17 / #20170260328

Methods for solid freeform fabrication

The present invention provides methods, processes, and systems for the manufacture of three-dimensional articles of polymer materials using 3d printing. A syringe or an inkjet print head prints a solution of prepolymer onto a build plate. ... University Of Washington

09/07/17 / #20170254887

Systems and methods for measuring pressure distributions of acoustic beams from ultrasound sources

The present technology relates generally to receiving arrays to measure a characteristic of an acoustic beam and associated systems and methods. The receiving arrays can include elongated elements having at least one dimension, such as a length, that is larger than a width of an emitted acoustic beam and another dimension, such as a width, that is smaller than half of a characteristic wavelength of an ultrasound wave. ... University Of Washington

08/31/17 / #20170250063

Methods and devices for generating double emulsions

The present disclosure describes devices and methods capable of generating multi-phase emulsions, including double emulsion droplets in a gas phase. The present disclosure also describes interfaces for coupling a multi-phase emulsion droplet source to an analytical instrument such as a mass spectrometer. ... University Of Washington

08/31/17 / #20170249932

Confinement or movement of an object using focused ultrasound waves to generate anultrasound intensity well

A method includes transmitting a focused ultrasound wave into a medium to form (i) an ultrasound intensity well within the medium that exhibits a first range of acoustic pressure and (ii) a surrounding region of the medium that surrounds the ultrasound intensity well and exhibits a second range of acoustic pressure that exceeds the first range of acoustic pressure. The method further includes confining an object within the ultrasound intensity well. ... University Of Washington

08/31/17 / #20170248551

Inspection of structures

A method of detecting inconsistencies in a structure is presented. A pulsed laser beam is directed towards the structure. ... University Of Washington

08/31/17 / #20170247687

Error detection in sequence tag directed subassemblies of short sequencing reads

The invention provides methods for preparing dna sequencing libraries by assembling short read sequencing data into longer contiguous sequences for genome assembly, full length cdna sequencing, metagenomics, and the analysis of repetitive sequences of assembled genomes.. . ... University Of Washington

08/31/17 / #20170247419

Desmoglein 2 (dsg2) binding proteins and uses therefor

The present invention provides recombinant adenoviral compositions and methods for their use in treating disorders associated with epithelial tissues.. . ... University Of Washington

08/31/17 / #20170246805

Methods for solid freeform fabrication

The present invention provides high performance polymer (hpp) compositions, methods, processes, and systems for the manufacture of three-dimensional articles made of polymers using molding or 3d printing. The hpp compositions comprise a first hpp dissolved in a solvent and a second hpp present as a solid.. ... University Of Washington

08/31/17 / #20170246311

Peptides for binding alternatively activated macrophages

M2 macrophage-binding peptides and polymers and related methods of use are described.. . ... University Of Washington

08/24/17 / #20170240861

Human pluripotent stem cell derived endocardial endothelium

Provided herein are methods that enable the polarization of hpsc mesoderm such that closely related yet distinct cardiovascular populations can be generated efficiently without the need of post-facto enrichment.. . ... University Of Washington

08/24/17 / #20170240695

Metathesis polymerization methods

The present disclosure is directed to methods of making a polymer, including exposing a reaction mixture including a strained cyclic unsaturated monomer and an organic initiator to a stimulus to provide an activated organic initiator, whereby the activated organic initiator is effective to polymerize the strained cyclic unsaturated monomer via a 4-membered carbocyclic intermediate to provide a polymer having constitutional units derived from the strained cyclic unsaturated monomer.. . ... University Of Washington

08/17/17 / #20170234990

Pet detector scintillator arrangement with light sharing and depth of interaction estimation

A photon detector includes a sensor array of optical sensors disposed in a plane and four substantially identical scintillation crystal bars. Each optical sensor is configured to sense luminescence. ... University Of Washington

08/17/17 / #20170234849

Detection of thermal damage of composites using molecular probes

Improved methods of detecting thermal exposure are provided herein. The provided methods utilize initially dormant luminescent probes incorporated into a matrix to form a composite. ... University Of Washington

08/17/17 / #20170233722

Combinatorial photo-controlled spatial sequencing and labeling

Methods of labeling or barcoding molecules within one or more portions of a plurality of cells are provided. Kits and systems for labeling or barcoding molecules within one or more portions of a plurality of cells are also provided. ... University Of Washington

08/17/17 / #20170233426

Method for 2-sulfation of glycosides

Method for selective 2-sulfation of glycosides.. . ... University Of Washington

08/17/17 / #20170231979

Methods and compositions for treating vasomotor symptoms

The present disclosure is generally directed to compositions and methods for treating or limiting development of vasomotor symptoms in a subject.. . ... University Of Washington

08/10/17 / #20170227494

Analyte sequencing with nanopores

Provided herein are methods and systems pertaining to sequencing units of analytes using nanopores. In general, arresting constructs are used to modify an analyte such that the modified analyte pauses in the opening of a nanopore. ... University Of Washington

08/10/17 / #20170225395

Three-dimensional printed mechanoresponsive materials and related methods

The present disclosure provides additive manufacturing methods that include depositing onto a substrate a material including a blend of a mechanochromic molecule and a matrix polymer; and fusing the material to provide an article. The mechanochromic molecule has a first end and a second end and includes at least one polymer chain covalently bound to each end.. ... University Of Washington

08/03/17 / #20170218029

Polypeptides for use in self-assembling protein nanostructures

Synthetic nanostructures, polypeptides that are useful, for example, in making synthetic nanostructures, and methods for using such synthetic nanostructures are disclosed herein.. . ... University Of Washington

08/03/17 / #20170215728

Applanation tonometer

Intraocular pressure measurement devices and techniques for use therewith are generally described. In some examples the pressure measurement device may include a sleeve comprising a lower end including a first opening and an upper end. ... University Of Washington

07/27/17 / #20170211143

Methods of determining tissues and/or cell types giving rise to cell-free dna, and methods of identifying a disease or disorder using same

The present disclosure provides methods of determining one or more tissues and/or cell-types contributing to cell-free dna (“cfdna”) in a biological sample of a subject. In some embodiments, the present disclosure provides a method of identifying a disease or disorder in a subject as a function of one or more determined more tissues and/or cell-types contributing to cfdna in a biological sample from the subject.. ... University Of Washington

07/20/17 / #20170208597

Power transmission using wireless communication signals

Examples described herein include wireless transmitters configured for power transmission. Example wireless transmitters may insert power packets into wireless communications such that power harvesting circuitry may harvest sufficiently continuous power from the wireless communication signals. ... University Of Washington

07/20/17 / #20170205421

Synthetic yeast agglutination

The present invention provides methods and compositions that can be applied to screening protein-protein interaction networks, screening drug candidates that modulate protein-protein interactions for on- and off-target effects, detecting extracellular targets for which no native s. Cerevisiae receptor exists, and re-engineering yeast agglutination in order to answer biological questions about yeast speciation and ecological dynamics. ... University Of Washington

07/20/17 / #20170205318

Ultrasound system for shearing cellular material

A system for processing biological or other samples includes an array of transducer elements that are positioned to align with sample wells in a microplate. Each transducer element produces ultrasound energy that is focused towards a well of the microplate with sufficient acoustic pressure to cause inertial cavitation. ... University Of Washington

07/20/17 / #20170202950

Highly immunogenic hiv p24 sequences

The invention relates to peptides comprising part or all of a conserved element within a center-of-tree (cot) sequence derived from a family of polypeptides encoded by naturally occurring variants of hiv. The invention also relates to immunogenic compositions and vaccines comprising said peptides. ... University Of Washington

07/13/17 / #20170200033

Systems and methods for enabling user interactions with wireless tags

There is provided a system including a wireless tag reader, a first wireless antenna, a wireless tag including an integrated circuit (ic), a conductive element electronically connecting the wireless tag to the first wireless antenna, a non-transitory memory storing an executable code, a hardware processor executing the executable code to transmit an interrogation signal, receive a tag signal from the wireless tag electronically connected to the first wireless antenna in response to the interrogation signal, the tag signal including a wireless tag identification (id) uniquely identifying the wireless tag, and determine an interaction by a user with the wireless tag based on the tag signal.. . ... University Of Washington

07/13/17 / #20170199149

Nanopore-based analysis of protein characteristics

Methods for nanopore-based protein analysis are provided. The methods address the characterization of a target protein analyte, which has a dimension greater than an internal diameter of the nanopore tunnel, and which is also physically associated with a polymer. ... University Of Washington

07/13/17 / #20170198363

Compositions and methods for detection of small molecules

Compositions and methods are provided for the detection of small molecules in a cell using biosensor molecules comprising conditionally active ligand binding domains. Compositions for conditionally activating transcription based on the presence of a small molecules in a cell are further provided, together with methods of designing, producing, and expressing biosensor molecules in cells.. ... University Of Washington

07/13/17 / #20170196292

Layered materials and structures for enhanced impact absorption

A garment worn by a wearer has an exterior shell and an interior shell with various impact absorbing material between the exterior shell and the interior shell. The impact absorbing material includes multiple structures, such as rods or filaments, capable of deforming when force is applied then returning to its state prior to application of the force. ... University Of Washington

06/29/17 / #20170184543

Isotachophoretic device and methods

The present disclosure relates to devices and methods for performing isotachophoretic concentration of analytes using a porous matrix, for example, for use in diagnostic assays such as lateral flow assays. For example, the disclosure provides a method of concentrating an analyte in a sample. ... University Of Washington

06/29/17 / #20170184520

X-ray spectrometer with source entrance slit

An example spectrometer includes a crystal analyzer having a radius of curvature that defines a rowland circle and a sample stage configured to support a sample such that the sample is offset from the rowland circle. The spectrometer further includes an x-ray source aligned to emit x-rays toward the sample and an entrance slit formed within a material that is opaque to x-rays. ... University Of Washington

06/29/17 / #20170182137

Breast and ovarian cancer vaccines

The compositions described herein include an epitope of a peptide that may elicit an immune response in a subject following administration. The compositions may comprise nucleic acids. ... University Of Washington

06/22/17 / #20170180178

Apparatuses, systems, and methods for communicating using mimo and spread spectrum coding in backscatter of ambient signals

Apparatuses, systems, ambient rf backscatter transceivers, and methods for communicating using mimo and spread spectrum coding of backscattered ambient rf signals are described. An example system may include an ambient rf backscatter transceiver that include an antenna configured to receive a backscattered ambient radio frequency (rf) signal, and a receiver coupled to the antenna. ... University Of Washington

06/22/17 / #20170180075

Wireless networking communication methods, systems, and devices operable using harvested power

Example devices described herein include endpoint devices which may communicate with an access point device by modulating a channel associated with the wireless communication to encode transmit data. The channel modulation may be performed by utilizing a switch to control an impedance of an antenna at the endpoint device to either reflect or absorb wireless network communication signals received by the endpoint device. ... University Of Washington

06/22/17 / #20170176393

Composite inspection

A method of detecting material changes in a composite structure is presented. A pulsed laser beam is directed towards the composite structure comprised of a number of composite materials. ... University Of Washington

06/22/17 / #20170176322

Composite inspection

A method of detecting local material changes in a composite structure is presented. A pulsed laser beam is directed towards the composite structure comprised of a number of composite materials. ... University Of Washington

06/22/17 / #20170175174

Methods and apparatus for performing digital assays using polydisperse droplets

Methods, devices, and systems for performing digital assays are provided. In certain aspects, the methods, devices, and systems can be used for the amplification and detection of nucleic acids. ... University Of Washington

06/22/17 / #20170175136

Genomic insulator elements and uses thereof

Provided herein are methods for identifying high potency genomic insulator elements that can be used in a vector composition e.g., that are useful for preventing unwanted expression of neighboring genes, such as proto-oncogenes, when administered to a subject in need thereof. Also provided herein are methods for treating disease and methods for administering a nucleic acid to a subject using such vectors.. ... University Of Washington

06/22/17 / #20170174907

Marine coatings

Marine coatings including cationic polymers hydrolyzable to nonfouling zwitterionic polymers, coated marine surfaces, and methods for making and using the marine coatings.. . ... University Of Washington

06/22/17 / #20170173190

Gadolinium expressed lipid nanoparticles for magnetic resonance imaging

Lipid nanoparticles expressing metal ions and methods for using the compositions for magnetic resonance imaging.. . ... University Of Washington

06/22/17 / #20170173185

Globin gene therapy for treating hemoglobinopathies

The presently disclosed subject matter provides for expression cassettes that allow for expression of a globin gene or a functional portion thereof, vectors comprising thereof, and cells transduced with such expression cassettes and vectors. The presently disclosed subject matter further provides methods for treating a hemoglobinopathy in a subject comprising administering an effective amount of such transduced cells to the subject.. ... University Of Washington

06/15/17 / #20170166875

Methods relating to nucleic acid sequence editing

The technology described herein is directed to engineered endonucleases whose activity is restricted to certain phases of the cell cycle. Provided herein are compositions and methods relating to such engineered endonucleases.. ... University Of Washington

06/15/17 / #20170165259

Combined modulation of ire1

Described herein, inter alia, are combined compositions of an ire1 kinase modulating compound and an ire1 ribonuclease modulating compound and methods of using the same.. . ... University Of Washington

06/08/17 / #20170162177

Methods and systems for providing presentation security for augmented reality applications

In some embodiments, an augmented reality system is provided that provides output security. In some embodiments, an operating system of the augmented reality system provides trusted management support for presenting virtual objects from untrusted applications executing in multiple isolated processes. ... University Of Washington

06/08/17 / #20170159103

Methods and compositions for assaying the activity of one or more lysosomal enzymes

Methods and liquid compositions for assaying the activity of one or more lysosomal enzymes in a sample are provided. In some embodiments, the assay is a multiplexed assay for the activities of a plurality of lysosomal enzymes in the sample. ... University Of Washington

06/01/17 / #20170150912

Determination of tissue oxygenation in vivo

A system and method for noninvasively determining the oxygenation of a tissue, for example, a muscle, in vivo uses optical methods to optically interrogate the tissue in both a visible wavelength range and a near infrared (nir) wavelength range. The illuminating light is sculpted in intensity to approximately match the absorbance spectrum, for example, with the visible light having an intensity an order of magnitude greater than the nir light. ... University Of Washington








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