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Vilnius University patents


Recent patent applications related to Vilnius University. Vilnius University is listed as an Agent/Assignee. Note: Vilnius University may have other listings under different names/spellings. We're not affiliated with Vilnius University, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "V" | Vilnius University-related inventors


Analysis of single-stranded rna

Provided is a method for modifying a ssrna at the 3′ end, said method comprising contacting the strand with a ssrna 2′-o-methyltransferase in the presence of a co-factor, under conditions which allow for the transfer by the ssrna 2′-o-methyltransferase of a part of the co-factor onto 3′ end of the ssrna to form a modified ssrna, wherein the ssrna bears 2′-oh group at 3′ terminal nucleotide and wherein the part of the co-factor transferred comprises a reporter group or a functional group.. . ... Vilnius University

Rna-directed dna cleavage by the cas9-crrna complex

. . Isolation or in vitro assembly of the cas9-crrna complex of the streptococcus thermophilus crispr3/cas system and use for cleavage of dna bearing a nucleotide sequence complementary to the crrna and a proto-spacer adjacent motif. Methods for site-specific modification of a target dna molecule in vitro or in vivo using an rna-guided dna endonuclease comprising rna sequences and at least one of an ruvc active site motif and an hnh active site motif; for conversion of cas9 polypeptide into a nickase cleaving one strand of double-stranded dna by inactivating one of the active sites (ruvc or hnh) in the polypeptide by at least one point mutation; for assembly of active polypeptide-polyribonucleotides complex in vivo or in vitro; and for re-programming a cas9-crrna complex specificity in vitro and using a cassette containing a single repeat-spacer-repeat unit.. ... Vilnius University

Easyly deployable phased antenna for a spacecraft and system of such antennas

An antenna is made from strips of a shape-memory alloy or other resilient material acting as a spring with attached branches that constitute individual monopole antennas. In the folded state, the antenna looks like a strip roll and can be placed on a satellite. ... Vilnius University

A compact lamp

The compact lamp consists of a light source, a focusing lens, a specially shaped secondary lens with a saddle-shaped output surface, a light transmitting element, a battery holding chamber with an electrical control circuit connected to a button for control of the lamp source via a magnetic contact. Some of these elements are placed inside the lamp housing, mounted on an end of a handlebar or another suitable lighting device, and some other elements, including the battery and the magnetic control circuit, are installed inside the handlebar tube or the housing of the lighting device. ... Vilnius University

Targeted rna knockdown and knockout by type iii-a csm complexes

Methods and compositions using a crispr-cas type iiia resulting in rna gene knockdown and knockout in an animal.. . ... Vilnius University

Systems and methods for barcoding nucleic acids

The present invention generally relates to microfluidics and labeled nucleic acids. For example, certain aspects are generally directed to systems and methods for labeling nucleic acids within microfluidic droplets. ... Vilnius University

System and method for a biomimetic fluid processing

A system and method are provided for harvesting target biological substances. The system includes a substrate and a first and second channel formed in the substrate. ... Vilnius University

Programmable rna shredding by the type iii-a crispr-cas system of streptococcus thermophilus

A type iii-a crispr-cas (stcsm) complex of streptococcus thermophilus comprising crrna, csm4, and csm3 and use for cleavage of rna bearing a nucleotide sequence complementary to the crrna, in vitro or in vivo. Methods for site-specific cleavage/shredding of a target rna molecule using an rna-guided rna endonuclease comprising a minimal complex of crrna, csm4, and csm3, and methods of rna knock-down and rna knock-out are disclosed.. ... Vilnius University

Conversion of alpha-hydroxyalkylated residues in biomolecules using methyltransferases

The present invention relates to targeted conversion of alpha-hydroxyalkylated residues in biomolecules in the presence of a directing methyltransferase, namely to targeted removal of the alpha-hydroxyalkyl moieties to give unmodified residues, or targeted derivatization of the alpha-hydroxyalkyl groups by covalent coupling of non-cofactor compounds represented by formula hq-lx, wherein x represents a functional group or a reporter group attached via a linker moiety l, and qh is selected from hs—, hse—, ho—h2n—, hn3 or hcn in the presence of a directing methyltransferase. Further development of the method of targeted conversion comprises methods for targeted labeling a biomolecule and method for detecting hydroxymethylated target sites in a biomolecule according to the present invention.. ... Vilnius University

Nucleic acid production and sequence analysis

A method for producing a nucleic acid molecule from a template nucleic acid sequence and a linking unit attached to a primer, which method comprises a step of contacting the template nucleic acid sequence with a nucleic acid polymerase under conditions which allow the nucleic acid polymerase to produce the nucleic acid molecule from the primer based on the template nucleic acid sequence, wherein the linking unit is attached to a target site in the template nucleic acid sequence with a covalent linkage.. . ... Vilnius University








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