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Wista Laboratories Ltd patents


Recent patent applications related to Wista Laboratories Ltd. Wista Laboratories Ltd is listed as an Agent/Assignee. Note: Wista Laboratories Ltd may have other listings under different names/spellings. We're not affiliated with Wista Laboratories Ltd, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "W" | Wista Laboratories Ltd-related inventors


Methods of chemical synthesis of diaminophenothiazinium compounds including methylthioninium chloride (mtc)

Methods of synthesizing and purifying certain 3,7-diamino-phenothiazin-5-ium compounds (referred to herein as “diaminophenothiazinium compounds”) including methythioninium chloride (mtc) (also known as methylene blue) are provided.. . ... Wista Laboratories Ltd

Methods of synthesis and/or purification of diaminophenothiazinium compounds

Disclosed are methods of synthesis and/or purification of certain 3,7-diamino-phenothiazin-5-ium compounds (“diaminophenothiazinium compounds”) including methylthioninium chloride (mtc) (methylene blue), and the resulting high purity characterized by a purity greater than 98%, and very low levels of heavy metals and organic impurities azure a, b, c and mvb. Also disclosed are methods of treatment of a tauopathy or methemoglobinemia in a patient in need thereof, comprising administering to the patient a therapeutically effective amount of the high-purity diaminophenothiazinium compound.. ... Wista Laboratories Ltd

Methods of chemical synthesis and purification of diaminophenothiazinium compounds including methylthioninium chloride (mtc)

This disclosure pertains generally to the field of chemical synthesis and purification, and more specifically to methods of synthesizing and purifying certain 3,7 diamino-phenothiazin-5-ium compounds (referred to herein as “diaminophenothiaziniumcompounds”) including methythioninium chloride (mtc) (also known as methylene blue). In one embodiment, the method comprises the steps of, in order: nitrosylation (nos); nitrosyl reduction (nr); thiosulfonic acid formation (tsaf); oxidative coupling (oc); cr(vi) reduction (cr); isolation and purification of zwitterionic intermediate (iapozi); ring closure (rc); chloride salt-formation (csf); one of: sulphide treatment (st); dimethyldithiocarbamate treatment (dt); carbonate treatment (ct); ethylenediaminetetraacetic acid treatment (edtat); organic extraction (oe); and recrystallisation (rx). ... Wista Laboratories Ltd








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